allergic contact dermatitis in humans experimental and quantitative aspects
Báo cáo y học: "Maternal allergic contact dermatitis causes increased asthma risk in offspring" pdf
... Th2-skewed allergic state might similarly increase asthma susceptibility in offspring In the current study we tested this hypothesis by inducing ACD in mothers using Th1 or Th2 inducing skin irritants ... (Luminex, Austin, TX) according to the manufacturer's instructions Standards and internal controls were added for each cytokine and diluted in serum-like medium Raw data were analyzed using Masterplex ... ACD and offspring susceptibility to OVA-induced asthma Maternal ACD and offspring susceptibility to OVA-induced asthma Following the suboptimal protocol, an increase in mononuclear and eosinophilic...
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The Elizabethan Parish in its Ecclesiastical and Financial Aspects ppt
... laid down in the injunctions and articles they were sworn to observe, was the keeping in repair of the church fabric and its appurtenances, as well as the procuring and the maintaining in good ... and directs the Wardens of the Stationers to stay certain persons from the printing of primers and psalters in English and Latin, for which printing one Seres had obtained a monopoly C.R Rivington, ... chapter); the finding of clerk and sexton; the care of the poor; maintaining of the local roads and bridges; purchasing and repair of parish armor, and mustering of parish contingents; contributions...
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EPILEPSY IN CHILDREN – CLINICAL AND SOCIAL ASPECTS pptx
... corticotrophin releasing hormone (CRH) (15, 16) Experimental and clinical evidence exists for early microglial activation and inflammatory cytokine production in the developing brain in both hypoxia/ischemia ... neuropsychological 22 Epilepsy in Children – Clinical and Social Aspects problems These findings in our study provide further support for the integral involvement of the prefrontal cortex in CSWS Acknowledgment ... ranging in age from to 12 years Clinical indications for MR imaging were suspected speech delay, brain trauma, brain tumor, short stature and migraine, which turned out to be neurologically and...
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Báo cáo y học: "Cartilage-specific autoimmunity in animal models and clinical aspects in patients – focus on relapsing polychondritis" ppsx
... production in RP patients [15,16] Surprisingly, a more prominent response was seen for CIX and CXI in a patient presenting a fatal tracheomalacia, indicating CIX and CXI rather than CII as being involved ... dominating symptom is inflammation in the peripheral joints characterized by redness, swelling and pain, which mimic the symptoms of arthritis in RP patients In the majority of the rodent strains, ... have not yet been investigated in RP patients Adjuvants and oils can induce arthritis in many rat strains [33–36] and auricular chondritis in Wistar rats [21] Finally, in FH and Wistar rats, chondritis...
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Báo cáo y học: "Quantitative expression of osteopontin in nasal mucosa of patients with allergic rhinitis: effects of pollen exposure and nasal glucocorticoid treatment" pdf
... gland (Figure 1B) endothelial cells In most cells, the most prominent staining was observed in the nuclei The most intense staining was observed in epithelial and endothelial cells, but also in ... osteopontin in nasal biopsies Representative pictures of immunostaining for osteopontin in nasal biopsies of allergic rhinitis patients (peak-season, placebo treated) (×400) in epithelium (A) and glands ... 0.82) Discussion There is an increased scientific interest in the putative role of OPN in several diseases, including asthma, allergy and rhinosinusitis [7,10,14,15] In the current study, we have...
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Báo cáo y học: "Effect of Acute Administration of an Herbal Preparation on Blood Pressure and Heart Rate in Humans"
... treatment ingestion After eating, an increase in heart rate occurred in all three treatment groups The increase in heart rate does not coincide with the pharmacokinetics including blood levels and ... GJ Coronary spasm and thrombosis in a bodybuilder using a nutritional supplement containing synephrine, octopamine, tyramine and caffeine So African Med J 2008; 98: 372-373 Sander LC, Putzbach ... receptor binding It is well known that, in general, binding to α-adrenergic receptors results in vasoconstriction, with increased cardiovascular contractility and increased heart rate occurring in response...
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An experimental investigation on hydrogen fuel injection in intake port and manifold with different EGR rates
... for the injector opening Based on the preset timing and duration the injector was opened for injection and closed after injection The injection timing and injection duration was varied within the ... by times in port injection and times in manifold injection however there is an increase in smoke by 36 % in port injection and 44 % in manifold injection The CO emission is found to be increases ... ratios In order to minimize the possibility of flashback occurrence, the injection timing of the hydrogen injection was fixed in coordination with the intake valve opening timing Hydrogen used in...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 17)
... sampling until injection to GC, and from the standard solution to a test specimen) In principle, the sampling, extraction and GC analysis should be made at low temperature, in a gastight state and ... mg/mL), and kept airtightly in a refrigerator A 5-µL volume of the above solution is placed using a microsyringe in a glass vial containing mL of dimethyl sulfoxide (DMSO), capped airtightly and ... nitrite inhalant in rat and human blood: application for pharmacokinetic investigations J Chromatogr B 734:83–89 11) Kielbasa W, Fung HL (2000) Pharmacokinetics of a model organic nitrite inhalant and...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 67)
... eye mucosa and the skin results in its poisoning In the murder terrorism with VX taking place in Osaka, Japan, 1994, VX was sprayed on the back of the neck of the victim using a syringe (the exposure ... metabolism and decomposition in human bodies The detection limits of DAEMS in serum are about 50 ng/mL in the scan mode and about ng/mL in the SIM mode > Figure 2.3 shows a TIC, mass chromatograms and ... resulting acetonitrile layer is transferred to another test tube To the remaining aqueous phase, mL acetonitrile is again added, shaken and centrifuged The acetonitrile layers obtained are combined,...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 20)
... 11-nor-9-carboxy-∆9tetrahydrocannabinol in urine J Anal Toxicol 8:255–259 13) Foltz RL, McGinnis KM, Chinn DM (1983) Quantitative measurement of ∆9-tetrahydrocannabinol and two major metabolites in physiological specimens using ... factory worker was killed by being caught in a machine during working with it The concentrations of ∆9-THC-11-oic acid measured by GC/MS were 78 and 12 ng/mL in urine and blood, respectively; 0.7 ... ME, Sadler BM, Brine D et al (1983) Metabolism, disposition, and kinetics of delta-9-tetrahydrocannabinol in men and women Clin Pharmacol Ther 34:352–363 2) Agurell S, Halldin M, Lindgren J-E et...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 21)
... Main metabolic pathways of morphine, heroin and codeine The thick and thin arrows show the main and minor metabolic pathways, respectively ⊡ Figure 3.1 196 Morphine and its analogues GC and ... morphine Trends Neurosci 23:436–442 205 206 Morphine and its analogues 8) Matsubara K, Fukushima S, Akane A et al (1992) Increased urinary morphine, codeine and tetrahydropapaveroline in Parkinsonian ... Poppy seed ingestion and opiates urinalysis: a closer look J Anal Toxicol 14:308–310 10) Hasegawa M, Maseda C, Kagawa M et al (1992) Morphine and codeine being contained in poppy seeds and poppy...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 70)
... In > Table 5.1, clinical symptoms according to the concentrations of methemoglobin are presented ⊡ Table 5.1 Clinical symptoms appearing according to methemoglobin concentrations Methemoglobin ... Cyanosis in infants caused by nitrates in well water JAMA 257:2788–2792 12) Fan AM, Steinberg VE (1996) Health implications of nitrate and nitrite in drinking water: an update on methemoglobinemia ... containing nitrate salt can be considered However, a form or a product containing nitrate ingested could not be specified in the present poisoning case Notes a) When nitrite is present in blood,...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 71 and End)
... determination of methemoglobin in blood containing carboxyhemoglobin Forensic Sci Int 17:177–184 7) Sato K (1983) A method for determination of methemoglobin in blood containing carboxyhemoglobin ... Microdetermination of oxyhemoglobin, methemoglobin and sulfhemoglobin in a single sample of blood J Biol Chem 126:655–662 2) Leahy T, Smith R (1960) Notes on methemoglobin determination Clin Chem ... is read using cuvette A as reference, and this reading is A1 After allowing cuvette D to stand for 10 min, the absorbance at 630 nm is read using cuvette C as reference, and this reading is A3...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 22)
... suggesting a relatively short period between the times of his ingestion and death In addition, the ratios of cocaine to BE in blood and in the brain, and the brain-to-blood ratios of cocaine and ... 10.6 on average for urine sampled 0–8 h after the inhalation The ratios increased according to the increase in time interval between the inhalation and samplings [13–15] In the present case, the ... EL et al (1977) Cocaine and benzoylecgonine excretion in humans J Forensic Sci 22:697–707 15) Amber J (1985) The urinary excretion of cocaine and metabolites in humans: a kinetic analysis of published...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 23)
... two autopsy cases of pentazocine poisoning, its concentrations were 9.2 and 3.3 µg/mL in blood, 43 and 34 µg/g in the liver, and not detectable and 4.5 µg/mL in urine, respectively [12] The blood ... retention times of 3–7 and 7–8 min, respectively The amount of pentazocine and IS spiked into mL of blank whole blood or urine was equally 50 ng ⊡ Figure 5.2 222 Pentazocine Pentazocine In two autopsy ... pentazocine in blood The recovery of pentazocine using the Sep-Pak C18 cartridge was close to 100 % for both whole blood and urine [8] In this method, dextromethorphan is used as IS; the drug is being...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 24)
... (ed) (1992) Standard Methods of Chemical Analysis in Poisoning – With Commentary – Nanzando, Tokyo, p 43 and p 151 (in Japanese) 3) Cody JT (2000) Hallucinogens In: Bogusz MJ (ed) Handbook of Analytical ... center were 0.5–1.9 ng/mL in blood and 0.2–7.7 ng/mL in urine [4] References 1) Tu AT (1999) Principle of Toxicology – Science of Poisons – Jiho Inc., Tokyo, pp 108–109 (in Japanese) 2) The Pharmaceutical ... to contain LSD, the drug is extracted by adding % tartaric acid aqueous solution and by shaking it for This procedure is repeated six times and the tartarate extract solutions are combined After...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 25)
... determination of amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine, 3,4-methylenedioxymethamphetamine, and 3,4-methylenedioxyethylamphetamine in urine by solid-phase extraction and GC-MS: ... from the Greek and Latin origins; “en”, “gen” and “tactus” mean “within”, “produce” and “touch”, respectively Therefore, the word means “to produce a touching within” [1] b) MDA, MDMA and MDEA are ... catecholamine (including serotonin) release and blockade of reuptake resulting in cardiac and central nervous system effects [15] The effects of MDMA vary depending on its doses, frequency and duration...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 26)
... Medical 243 244 Phencyclidine Center At admission, he stared straight ahead, following commands but not responding verbally; the levels of serum creatinin kinase and aspartate aminotransferase were ... (GABA), and also a potent inhibitory neurotransmitter [2] GHB has a distinct presynaptic receptor in the brain [3], and is an agonist of GABAB receptors [4–8] GHB was first synthesized in 1960 and ... dichloromethane containing cyclized GHB is more than 100 µL in the vial, the proportion of dichloromethane gas, being contained in the headspace vapor to be injected after heating, becomes too high;...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 27) ppt
... Poisoning due to psychotropic agents Adverse Drug React Acute Poisoning Rev 4:83–126 3) Geraut A, Kintz P, Traqui A et al (1994) Toxicological findings in a fatality involving chlorpromazine Bull Int ... distinct peaks However, peaks of perazine, prochlorperazine, thiethylperazine and perphenazine were small and also interfered with by impurity peaks; low concentrations of these compounds in human ... following LC/MS becomes very useful LC/MS analysis [8] See [8] Reagents and their preparation i Reagents Prochlorperazine, trifluoperazine, perphenazine, fluphenazine, propericiazine and thioridazine...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 28) pptx
... and dyskinesia of the face, appeared Thus, diphenhydramine was injected into her intravenously; she recovered days after admission For the male baby, similar treatments, such as intravenous injection ... (1995) Simultaneous determination of haloperidol and its neurotoxic metabolite in plasma and brain tissue from schizophrenic patients treated with haloperidol using HPLC and solidphase extraction ... procedure i–v described in the GC/MS analysis section is followed for a urine or blood specimen to obtain a residue containing butyrophenones The residue is dissolved in 0.1 mL of the mobile...
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