adjuvant online review of evidence concerning its validity and other considerations relating to its use in the nhs
EVALUATION OF THE LEAN APPROACH TO BUSINESS MANAGEMENT AND ITS USE IN THE PUBLIC SECTOR
... ability to engage in Lean and continuous improvement • Chapter 8, Summary of Research Findings, draws together the key findings in order to present the success factors and barriers in implementing ... order to both place the remaining findings into context and to help identify and define Lean for the public sector A Descriptions of Lean 3.3 Of all the organizations involved in the case study work, ... recognized the Lean thinking origins of the improvement work “While the methodology has its roots in Lean, in the end, perhaps because of its ‘Lean and mean’ connotations, the phrase used to describe the...
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Examination Guidelines for Patent Applications relating to Biotechnological Inventions in the Intellectual Property Office
... Kirin-Amgen Inc and others v Hoechst Marion Roussel Ltd and others [2005] RPC (House of Lords) Kirin-Amgen Inc and others v Transkaryotic Therapies Inc and others [2003] RPC (Court of Appeal) International ... step in the light of judgments of the UK courts and decisions of the EPO Boards of Appeal as they relate to biotechnology in particular, and by their relevance to a specific step of the Windsurfing/ ... Kirin-Amgen Inc and others v Hoechst Marion Roussel Ltd and others [2005] RPC (HoL) Kirin-Amgen Inc and others v Transkaryotic Therapies Inc and others [2003] RPC (CoA) Population Diagnostics Inc...
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Astrology, Psychology, and The Four Elements An Energy Approach to Astrology & Its Use in the Counseling Arts_1 pptx
... people.) The faculty of intuition, on the other hand, Dffirent Approaches to Knowledge t9 reveals to the individual an immediate insight into, and perception of, the workings of the whole system being ... degree of insight into the workings of the four elements, and also to the many friends and students who have encouraged my writing and teaching Finally, we appreciate the permission of the following ... most meaningful development, one which assists them in becoming human, in relating to others, in being a person (p 52) approach to One of the few drawbacks of the humanistic to maintain an open,...
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Astrology, Psychology, and The Four Elements An Energy Approach to Astrology & Its Use in the Counseling Arts_2 pdf
... Language of Energy Key Concepts and Deftnitions A key to the understanding of all astrology is within the reach of anyone who truly understands the meaning of the following definitions: The PLANETS indicate ... impact of life's demands In order to this, the earth signs naturally need to get their feet in the mud once in a while, to get closeto nature, and to tune in on the power of growth in trees and ... exercising moderately, and getting sufficient rest In other words, by consciously accepting the limitations of the physical world, they can master it and make use of the sustaining power of the...
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Báo cáo y học: "ncreased serum HO-1 in hemophagocytic syndrome and adult-onset Still''''s disease: use in the differential diagnosis of hyperferritinemia" docx
... and their subsequent infiltration into other organs, accounting in part for the systemic clinical symptoms of these diseases [20] In response to various stresses, HO-1 is strongly expressed in ... activity during the clinical course in patients with HPS and ASD We next examined the relation between the serum HO-1 level and other laboratory parameters in the patients with HPS and ASD Because serum ... hematological malignancy, including non-Hodgkin's lymphoma, multiple myeloma, and acute myeloid leukemia, in three; and ASD and viral infection in the others The patients having more than two lineages...
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What is the impact of microfinance on poor people? a sysTemaTic review of evidence from sub-saharan africa pptx
... The impact of microfinance on the incomes of the poor b The impact of microfinance on wider poverty/ wealth of the poor c impact of microfinance on other non-financial The outcomes for the ... confounding factors at the I sampling stage but took steps to account for their influence in the analysis, the study was judged to be of medium quality and included in the in- depth review in the review ... symptom of the failure of micro-credit and not its success There is the potential for clients to remain in a cycle of borrowing or saving, investing in the future, increasing income, repaying...
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Báo cáo khoa học: Characterization of a membrane-bound angiotensin-converting enzyme isoform in crayfish testis and evidence for its release into the seminal fluid ppt
... spermatozoids, whereas the spermatogonia exhibit very faint staining only (Fig 4D) The thickness of the staining is the result of the morphology of spermatozoid in Astacus Indeed, the spermatozoid ... the lung, myocardium, liver, intestine and testis, as well as in the epithelial cells of the kidney and intestine [3] Its role in the regulation of the renin– angiotensin–aldosterone system has ... respectively In mammals, gACE was shown to be anchored in the cytoplasmic membrane of spermatozoids and to be released in the epididymal fluid during the transit of the sperm in the epididymis...
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báo cáo hóa học:"Differences in resistance mutations among HIV-1 non-subtype B infections: a systematic review of evidence (1996–2008)" pptx
... limited our review to RT and PR inhibitors and did not examine other drug classes currently in clinical use Our review is subject to reporting and publication bias We evaluated publications in the English ... variation so as to inform on the optimal use of limited ARV options in most of the world Better recording of clinical factors and longer follow up of patients will be required to determine whether novel ... located in different geographical areas This might improve the appropriateness of selection of certain drugs over others in the context of second-line or third-line therapeutic options In order to...
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Báo cáo hóa học: " Research Article A Review of Signal Subspace Speech Enhancement and Its Application to Noise Robust Speech Recognition potx
... the MV estimator—including its generalisation to the TDC estimator and the SDC estimator proved to give the best results However, the difference in performance with the optimal estimator remains ... is provided by the SDC estimator Here, the estimate is found by minimising the signal distortion subject to constraints on the energy of the projections of the residual noise onto the signal subspace ... variance Given the rank p of the clean speech, the MV estimate HMV is the best approximation of the original matrix Hs that can be obtained by making linear combinations of the columns of Hx : HMV...
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Báo cáo y học: "Chinese translation of strengths and difficulties questionnaire requires urgent review before field trials for validity and reliability" ppsx
... work in the Chinese population There is an urgent need to review the translation of the Chinese SDQ version before more studies use it in the field A more complete set of Chinese SDQ versions in ... Examples and explanation of these major differences and concerns are included in Table An online search on 12 June 2008, involving PsycINFO 1806, Ovid MEDLINE(R) 1996, CINAHL 1982 and EMBASE 1996 using ... because the wording matches more closely than the other English versions [2] It is available in traditional form of Chinese writing, commonly used in Hong Kong and Taiwan Chinese communities in...
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Cadmium Removal by the Hydroponic Culture of Giant Reed (Arundo donax) and Its Concentration in the Plant
... The plant body including rhizomes was plowed up, and transferred to the Institute of Industrial Science, the University of Tokyo Prior to laboratory experiments, the giant reed was cultured in ... liquid pump To avoid the direct effects on the removal of cadmium and phosphorus by parts other than the rhizome, the water level of the cultivation pot was kept lower than the top of the rhizome ... indicated that the GSH and subsequently produced phytochelatins affect the neutralization of toxic effects of cadmium that accumulated in the giant reed, which is similar to those of other gramineous...
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Expansion and its realization in the short story “the law of life” by jack london
... clause extends the meaning of another by adding something new to it’ Basically, there are two categories: addition (one clause adds to the meaning of another) and variation (one clause changes the ... for choosing the topic, the aims of the study, the methodology, the scope, and the design of the study Part B, the main part of the thesis, consists of three chapters Chapter 1, entitled Theoretical ... “was sitting”, “worked”, “listened”, “hated”… At the beginning of the story, the main character was introduced “an old Indian named Koskoosh” and the story is told from the point of view of this...
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Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx
... partitioning of the protein into an aggregated state The effect of copper binding on the secondary structure was determined using CD in the far UV To prepare proteins without Cu2+, part of each protein ... study the ability of stefin B to bind copper was assessed We used isothermal titration Copper binds to cystatin B calorimetry to monitor the binding event at pH and pH It was found that the protein ... understanding what causes the loss of appropriate metal binding might be crucial for the understanding of the role of amyloidogenic proteins in a number of neurodegenerative disorders Copper binds to...
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Tài liệu Báo cáo khoa học: Inorganic pyrophosphatase in the roundworm Ascaris and its role in the development and molting process of the larval stage parasites doc
... information concerning the kinetics and properties of the enzyme More strikingly, we show a novel role of the PPase enzyme in the development and molting process of A suum larvae in vitro constructed in ... PPases in the hypodermal cells of sectioned adult worms in immunohistochemical staining), and that the inhibition of PPasecatalyzed PPi hydrolysis by these inhibitors, is likely to prevent the synthesis ... important that the hypodermis of the body wall, which synthesizes components of the cuticle, may offer a useful target for studies into the mechanism of the development and molting process in the roundworms...
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Báo cáo khoa học: Interaction between catalytically inactive calpain and calpastatin Evidence for its occurrence in stimulated cells docx
... addition of E64, a synthetic inhibitor of calpain, did not modify the intensity of the signal observed in the presence of Ca2+ alone The increase in the mAb-binding capacity of calpain observed in these ... conformation, and that these can be monitored by evaluating the intensity of the light signal generated by the binding of mAb 56.3 To perform these investigations, the two preferential ligands of calpain, ... calpastatin becomes freely diffuse in the cytosol and only traces of aggregates remain located in the perinuclear region Thus, the increased availability of calpastatin, occurring in conditions of...
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Báo cáo khoa học: Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress pdf
... clarified in detail and could play a key role in the detoxification processes In this study we examined the role of Bcp2 in order to increase the knowledge of the enzymatic activity involved in the ... Furthermore, we report the cloning, the expression and the characterization of the recombinant protein rBcp2 in order to shed light on its role in the detoxification process and on its catalytic mechanism ... thioredoxin) In typical 2-Cys, Sp at the N terminus and SR at the C terminus belong to different subunits and condense to form an intersubunit disulfide bond; in atypical 2-Cys, Sp at the N terminus and...
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Báo cáo Y học: Functional expression of human liver cytosolic b-glucosidase in Pichia pastoris Insights into its role in the metabolism of dietary glucosides ppt
... combination of XhoI and BamHI, and subsequently the cDNA insert was puri®ed using the Qiaquick PCR puri®cation kit and ligated into the XhoI and BamHI sites of the pHIL-S1 vector, in phase with the ... following gradients were used: incubations containing arbutin or salicin as substrate; 100% C initial, increasing D to 20% (10 min), 50% (15 min), 100% (5 min), held at 100% (5 min); cyanodin glycosides; ... potent inhibitor of reCBG (Fig 3) Incubation of reCBG (0.35 lM ®nal concentration) in the presence of and lM inhibitor reduced the b-glucosidase activity in a time-dependent manner; 36 and 70% of the...
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Báo cáo khoa học: The first cytochrome P450 in ferns Evidence for its involvement in phytoecdysteroid biosynthesis in Polypodium vulgare doc
... on the dose of E applied to the calli and the incubation time This showed that levels of P450 protein measured by CO-binding spectra increased as a linear function of the E amount applied to the ... E to 20E biotransformation ratio was observed, and a high degree of inhibition for the other P450 inhibitors tested at a single dose was also determined In addition, 20E causes inhibition of ... presence of P450 The amount of protein was determined using the Bradford procedure with bovine serum albumin as a standard [42] The protein concentration of partially or total purified P450 protein...
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Báo cáo khoa học: Characterization of Trypanosoma brucei PEX14 and its role in the import of glycosomal matrix proteins pptx
... mislocalization of all three enzymes in these cells clearly shows the involvement of PEX14 in the targeting of PTS-1, PTS-2 and I-PTS proteins to the glycosome To further analyse the effect of the destruction ... N-terminal domain of the polypeptide of each of these organisms is followed by a stretch of hydrophobic amino acids that is presumably involved in the protein’s anchoring to the membrane Also in ... identified in yeast) PEX17 Several other peroxins are involved in the subsequent steps of the import The import of matrix proteins seems to involve a cascade of interactions between the cargo-loaded...
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The review of biomass pyrolysis oil properties and upgrading research
... Leahy and Dr Witold Kwapinski His PhD work involves studies of pyrolysis and second generation biorefining for the processing of carbohydrate waste materials and lignocellulose biomass to produce ... pressure) for the bio-refining process of wastes and biomass An analysis of the products formed as the parameters are varied will lead to an awareness of the transformation mechanisms involved DATE: ... About The Presenter Fergus holds an honours degree in Industrial Chemistry from the University of Limerick and is currently pursuing a PhD in the University His supervisors are Prof Michael...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25