acids mitochondrial function and the modulation of butyrate induction of cell maturation
Báo cáo khoa học: Altered expression of tumor protein D52 regulates apoptosis and migration of prostate cancer cells potx
... epithelial cells express TPD52 predominantly and that it may play a role in the development of the epithelial cell phenotype [13] Its expression is controlled by androgens in LNCaP cells [9] The ... Dysregulation of TPD52 affects the proliferation rate of LNCaP cells First, we studied whether overexpression or downregulation of TPD52 influences the proliferation rate of LNCaP cells To determine the ... initiate apoptosis The activation of caspases-3 and -9 taken together with the loss of mitochondrial membrane potential suggests that downregulation of TPD52 leads to activation of the intrinsic pathway...
- 11
- 444
- 0
ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 1 pps
... understanding of the anatomy and function of the ear and the auditory nervous system, and it discusses the cause and treatment of hearing disorders Most books on hearing focus either on the anatomy ... perception of the function of the cochlea The best description of the function of outer hair cells is that they act as “motors” that counteract the frictional losses of energy in the cochlea ... accumulated about the function of the cochlea than of any other sensory organ C H A P T E R Anatomy of the Ear ABSTRACT 10 The ear consists of the outer ear, the middle ear and the inner ear The outer...
- 33
- 398
- 1
ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 2 ppsx
... at the entrance of the ear canal compared with the sound pressure that is measured in the place of the head The effect of the head on the sound at the entrance of the ear canal is related to the ... that of the basilar membrane and that the deflection of the stereocilia of inner hair cells, that is the basis for excitation of auditory nerve fibers, is not a direct function of the motion of the ... remarkable in the light of the FIGURE 2.12 (A) Average displacements of the umbo, the head of the stapes and the lenticular process of the incus (B) The lever ratio at 124 dB SPL at the tympanic...
- 33
- 374
- 0
ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 4 potx
... in the ventral parts of the MGB of the thalamus, the nonclassical sensory pathways use the dorsal and medial division of the MGB as relay (Fig 5.10) [122] These divisions of the MGB receive their ... is the difference in the arrival time and the difference in the intensity of sounds at the two ears, both factors being a function of the azimuth The time between the arrival of sounds at the ... Activation of a cell therefore depends both on the activity in the fibers that impinge on a cell and on the efficacy of the synapses that connect the fibers to the cells Plastic changes consist of establishment...
- 33
- 738
- 0
ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 6 pot
... The caudal portion of the floor of the lateral recess is the (dorsal) surface of the dorsal cochlear nucleus and the rostral portion of the floor of the lateral recess is the dorsal surface of ... difference between the latency of the N1 of the AP and that of the response from the intracranial portion of the auditory nerve is the travel time in the auditory nerve from the ear to the recording ... the latency of the first peak in the dipole and the length is the relative strength of the dipoles Note the short distance between the two first dipoles (peak I and II of the ABR) and the third...
- 33
- 393
- 0
ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 7 pot
... and standard error of the mean are shown as a function of the intensity of the noise The TTS was measured 20 s after the end of the exposure In this study the noise exposure consisted of a band ... elevation of the reflex threshold of an average of dB The individual variation is large 4.2 Functional Importance of the Acoustic Middle-ear Reflex Many hypotheses about the functional importance of the ... basis of the elevation of the hearing threshold in disorders of the middle ear and the cochlea but the effect on the function of the nervous system may affect speech discrimination Impairment of speech...
- 33
- 464
- 0
ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 8 docx
... role of outer hair cells, that is to increase the sensitivity and frequency selectivity of the ear (cf Chapter 3) The widening of the tuning of the basilar membrane broadens the “slices” of the ... the sensitivity and the frequency selectivity of the ear and that it is the inner hair cells that transduce the motion of the basilar membrane 223 and control the discharge pattern of auditory nerve ... spectrum The amount of acquired hearing loss depends not only on the intensity of the noise and the duration of exposure but also on the character of the noise (frequency spectrum and time pattern) The...
- 33
- 381
- 0
ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 9 pdf
... of recruitment of loudness is the ear, most often the cochlea, but absence of function of the acoustic middle-ear reflex can also cause an abnormal growth of the sensation of loudness above the ... corresponding to the F1 frequency and the other corresponding to the frequency of F2 The rate of the impulses is that of F0 for voiced sounds, and a quasi-random rate (average of 100 pps) for ... determined on the basis of the output of 16 band-pass filters The output of the six band-pass filters with the largest amplitudes is coded in the impulses that are applied to the electrodes in the cochlea...
- 33
- 460
- 0
báo cáo hóa học:" Comparative study of 64Cu/NOTA-[D-Tyr6,beta-Ala11,Thi13,Nle14]BBN(6-14) monomer and dimers for prostate cancer PET imaging" potx
... influx of the radiotracer from the blood At h after the injection of 64Cu/NOTA-monomer, the radiotracer was still in the form of its parent in the blood suggesting that the increased uptake of the ... electroplating and 64Culabeling BF participated in the conception and design of the study LeR participated in the coordination of the study and reviewed the manuscript GB conceived of the study, ... explaining the results observed at the pancreas for the dimer The receptor binding of one BBN(6-14) unit will significantly enhance the local concentration of the other BBN(6-14) unit in the vicinity of...
- 28
- 298
- 0
báo cáo khoa học: "Control of prostate cancer associated with withdrawal of a supplement containing folic acid, L-methyltetrahydrofolate and vitamin B12: a case report" pps
... Ingestion of large amounts of FA affects the intra-cellular mix of folate vitamers from methyl-THF to non-methyl-THF [11,12] Lucock and Yates [12] and others have proposed that the intra-cellular ... balance between the use of methylene-THF for DNA-T rather than for methionine synthesis may depend on the presence of both the MTHFR 677T polymorphism and high serum levels of FA They noted that ... copies of the MTHFR (TT) allele are present in about 10% of the US population The concentrations of B vitamins and the presence of various coenzyme polymorphisms eventually affect gene expression and...
- 7
- 507
- 0
EFFECTS OF CHOLINE KINASE ACTIVITY ON PHOSPHOLIPID METABOLISM AND MALIGNANT PHENOTYPE OF PROSTATE CANCER CELLS
... growth medium of the cells It therefore appears that the two pathways, phosphorylation and oxidation of choline, are both augmented in the course of malignant transformation of mammary cells (Katz-Brull ... (C) and the fourth (D) strands of this β-sheet is an α-helix that forms the interface stabilizing the protein as a dimer (helix 2) Amino acids belonging to the region connecting the third β-strand ... order of activation of the ternary complex by free Mg2+ The release of phosphocholine occurred prior to that of ADP- Mg2+ Thus, the overall rate of reaction was probably limited by the release of...
- 121
- 176
- 0
Tài liệu Transmission and Pathogenesis of Tuberculosis docx
... places other than the lungs, including the larynx, the lymph nodes, the pleura, the brain, the kidneys, or the bones and joints In HIV-infected persons, extrapulmonary TB disease is often accompanied ... case of TB The process of LTBI begins when extracellular bacilli are ingested by macrophages and presented to other white blood cells This triggers the immune response in which white blood cells ... infectious TB The longer the duration of exposure, the higher the risk for transmission Frequency of exposure to infectious person The more frequent the exposure, the higher the risk for transmission...
- 26
- 578
- 0
Tài liệu Báo cáo khoa học: SREBPs: physiology and pathophysiology of the SREBP family ppt
... Physiology and pathophysiology of the SREBP family H Shimano at G1 [19] In particular, p21 is a direct target of SREBP [20] The role of SREBP-1a in the regulation of cell growth and the cell cycle ... problems SREBP as the global lipid regulator SREBP-1a is highly expressed in growing cells, and it activates the synthesis of a variety of lipids, such as fatty acids, triglycerides, and phospholipids, ... H Shimano Physiology and pathophysiology of the SREBP family SREBP-1c and lipogenesis The SREBP family consists of three isoforms: SREBP1a, SREBP-1c, and SREBP-2 Each isoform has a different...
- 6
- 574
- 1
ANATOMY, PHYSIOLOGY, AND PATHOPHYSIOLOGY FOR ALLIED HEALTH pot
... between the sphenoid bone and the nasal bones They also form part of the floor of the cranium Ear ossicles are the smallest bones of the body They are the malleus, incus, and stapes and are in the ... Bones of the Shoulders, Arms, and Hands The bones of the shoulders are called pectoral girdles and include clavicles and scapulae They function to attach the arm to the trunk of the body The clavicles ... Disorders of the Endocrine System 135 Chapter 11: Special Senses 139 The Nose and the Sense of Smell 140 The Tongue and the Sense of Taste 140 The Eye and the Sense of Sight 140 Educating the Patient/Eye...
- 241
- 1,077
- 1
THE BIOLOGY, PHYSIOLOGY AND SOCIOLOGY OF REPRODUCTION ALSO SEXUAL HYGIENE WITH SPECIAL REFERENCE TO THE MALE docx
... the company of his young lady friend—through the pressure of her hand upon his arm, the lithe, graceful movement of body and limbs, the smile, the light in the eye and the soft voice All of these ... muscle and glands and the consumption of the cell substances of these tissues results in the development of the nerve, muscle [34 ]and gland cells into a condition larger, better equipped and more ... Summary of Principles 24 a The propagation of offspring and the protection and support of the young and defenseless, always involve sacrifice on the part 24 of the parents and the stronger members of...
- 100
- 424
- 0
Lung cancer - The diagnosis and treatment of lung cancer pdf
... summary of the evidence on which the guidance is based is provided in the full guideline (see Section 5) The development of this guideline for England and Wales coincided with the review by the Scottish ... of the symptoms at presentation, the time between onset of symptoms and presentation, the stage at presentation and the reasons for delay in presentation 4.2 Chemotherapy for NSCLC 4.2.1 Further ... examine the duration of follow-up and whether regular routine follow-up is better than symptom-led follow-up in terms of survival, symptom control and quality of life 4.5.2 The impact of the time...
- 41
- 470
- 0
A TREATISE ON ANATOMY, PHYSIOLOGY, AND HYGIENE DESIGNED FOR COLLEGES, ACADEMIES, AND FAMILIES potx
... For these reasons, the study of the structure of the human system, and the laws of the different organs, are subjects of interest to all, the young and the old, the learned and the unlearned, the ... parts: 1st The bones of the Head 2d The bones of the Trunk 3d The bones of the Upper Extremities 4th The bones of the Lower Extremities 75 The bones of the HEAD are divided into those of the Skull, ... view in the study of physiology, is the invigoration and improvement of the corporeal powers and functions, the preservation of health, and the prevention of disease.” The design of the following...
- 568
- 442
- 0
Guidelines for the early detection and screening of breast cancer ppt
... be the focus of family life The impact of breast cancer is therefore profound on both the woman diagnosed with the disease and her family Their fear and anxiety over the eventual outcome of the ... the strengths of the family, offers community and other normal forms of support during the most difficult stages of the illness, and assists the family in making the journey in a productive and ... the stages of treatment, the services offered and available, and the course of treatment and recuperation expected As important, is educating the woman and her family in the early detection of...
- 57
- 489
- 0
INTENSIVE LIFESTYLE CHANGES MAY AFFECT THE PROGRESSION OF PROSTATE CANCER docx
... lignans and other substances, are protective of normal cells The significant correlation between degree of changes in diet and lifestyle and degree of change in PSA and LNCaP cell growth adds to the ... strength of evidence While the evidence linking the effects of diet and lifestyle on the development and progression of prostate cancer is not conclusive, it is hardly meager A wide body of evidence ... States and either the primary or secondary cause of death of most men with prostate cancer, and obesity is of widespread concern In earlier randomized controlled trials we found that these changes...
- 6
- 629
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25