absorption distribution metabolism and excretion of drugs in neonates and young infants
Báo cáo khoa học: "Disposition kinetics and urinary excretion of ciprofloxacin in goats following single intravenous administration" doc
... Pharmacokinetics of ciprofloxacin in cow calves Indian J Anim Sci 1997, 67, 505-506 18 Kunin CM Clinical pharmacology of the new penicillins The importance of serum protein binding in determining ... a single administration of [14C] ciprofloxacin in albino rats and rhesus monkeys Drug Res 1986, 36, 1496-1502 Singh K, Srivastava AK Pharmacokinetics and urinary excretion of ciprofloxacin in ... extent of protein binding was determined in vitro using an equilibrium dialyzing technique as described by Kunin [18] To estimate the protein binding of ciprofloxacin, the drug was dissolved in 0.06...
- 5
- 343
- 0
Báo cáo y học: "Measuring effectiveness of drugs in observational databanks: promises and perils" pdf
... analyses of long-term effectiveness using observational research databases The Food and Drug Administration of the USA has introduced a requirement for post-marketing surveillance of newer drugs including ... long way in improving the use of databanks Many of the problems with observational studies can be minimized with careful planning in advance of the study Ideally the subjects in longitudinal databanks ... Read JL: Auranofin therapy and quality of life in patients with rheumatoid arthritis Results of a multicenter trial Am J Med 1986, 81: 565-578 Pincus T: Limitations of randomized clinical trials...
- 4
- 225
- 0
Trends in Social Media of US in Marketing to young customers and its effect pot
... lectures, discuss, and talking things through The aural preference includes talking aloud than debating and arguing to other people They get information through saying their idea and sharing it to someone ... perspective, warning that the speed of response of SNS and its constant interactivity are great demands on time and resources and that the level of preparedness of professionals implementing these tools ... Porter (2010) explained Zufryden’s model of marketing planning in their study of ‘Effectiveness of Official Websites Versus Online Promotional Contest’ and highlight that advertising increases awareness,...
- 88
- 508
- 0
Báo cáo y học: " G-CSF and IL-8 for early diagnosis of sepsis in neonates and critically ill children – safety and cost effectiveness of a new laboratory prediction model: study protocol of a randomized controlled trial [ISRCTN91123847]" pps
... including differential and plasma levels of C-reactive protein Routine surveillance for ventilator-associated pneumonia comprises microbiological examination of the tracheal aspirate, including ... error under 5% and a power of 80% is 2300 The expected follow up rate is in excess of 90% Because the unit of randomization is days and not individuals, an unknown intracluster (intraday) correlation ... the hypothesis that routine surveillance by determination of cytokine levels in plasma and tracheal aspirates will allow safe discontinuation of antibiotic therapy within 24 hours if the proposed...
- 8
- 407
- 0
Distribution of secretory phopholipase group XIIA in the CNS and its role in lipid metabolism and cognition
... hippocampus including CA1-3 fields, dentate gyrus and brainstem (Shirai and Ito, 2004) The significance of PLA2 in maintaining membrane lipid homeostasis of the brain is evident in all these ... neurotransmitters like glutamate, acetylcholine, dopamine and norepinephrine During signal transduction, the movement of calcium ions into the axon terminals induces the docking of neurotransmitter filled vesicles ... inflammation is initiated in the astrocytes and microglia cells The activation of microglia cells during inflammation would stimulate the release of proinflammatory cytokines such as interleukin-1 and tumour...
- 134
- 321
- 0
Tài liệu Báo cáo khoa học: Abstract Integration of Metabolism and Survival PP-1 The metabolic switch in liver methionine metabolism pptx
... Ca2+-saturated and apocalmodulin with sphingosine, sphingosine-1-phosphate and ceramide, in vitro binding assays were carried out Changes in fluorescence of the tyrosine residues of calmodulin as well as of ... simplest sphingolipids, including sphingosine, sphingosine-1-phosphate and ceramide, besides being structural components of biological membranes and intermediates of sphingolipid metabolism, ... sphingosine-1-phosphate and sphingosylphosphorylcholine can mobilize calcium from internal sources, that sphingosine kinase binds to and is possibly regulated by calmodulin, and that sphingosine...
- 291
- 612
- 0
Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States pdf
... regarding PrEP in discordant couples who wish to conceive Discussion includes information on counseling, laboratory testing, and monitoring of individuals on PrEP and importance of reporting uninfected ... NICHD-HPTN 040 study and concerns regarding use of lopinavir/ritonavir in neonates o Addition of new pharmacokinetic data on nevirapine in preterm infants • Initial Postnatal Management of the HIV-Exposed ... considerations, including availability and cost of ARV drugs, accessibility of facilities for safe intravenous infusions during labor, and local recommendations regarding breastfeeding by HIV-infected...
- 235
- 1,501
- 0
Doctor of Philosophy in Mathematics Linear and Non-linear Operators, and The Distribution of Zeros of Entire Functions
... one of the following conditions holds: (1) f and g have interlacing zeros with form (i) or (iv) in Definition 22 and the leading coefficients of f and g are of the same sign, or (2) f and g have interlacing ... lie in a convex region K containing the origin, and if all the zeros of g(z) lie in (−1, 0), then the zeros of h(z) also lie in K (iii) If the zeros of f (z) lie in (−a, a) and the zeros of g(z) ... real zeros [66] Investigating the zeros of functions such as ξ(z) in (1.1) is a part of the theory of the location and distribution of zeros of entire functions ∞ For a sequence of real numbers...
- 104
- 494
- 0
Báo cáo khoa học: The intrinsic structure of glucose transporter isoforms Glut1 and Glut3 regulates their differential distribution to detergent-resistant membrane domains in nonpolarized mammalian cells potx
... contains amino acids 1–10 of Glut3, amino acids 13–271 of Glut1, and amino acids 291–496 of Glut3 Chimera B also contains amino acids 1–290 of Glut3, amino acids 272–450 of Glut1, and amino acids ... using 30 lL of lipofectamine diluted in 70 lL of Opti-MEM (Gibco-BRL) and lg of Glut ⁄ pCMV plus lg of GFP diluted in 100 lL of supplemental Opti-MEM in 100 mm dishes Cells were incubated in ... C-terminal tail of Glut3 contains a targeting motif directing the trafficking of basolateral-sorting Glut1 to the apical cell surface in MDCK cells [24] Recently, two proteins binding to the C-terminus...
- 11
- 440
- 0
Báo cáo khoa học: Increased glucose metabolism and ATP level in brain tissue of Huntington’s disease transgenic mice pdf
... bobbing, head tilting and circling The levels of the endogenous (wild-type) huntingtin protein and the transgene product were examined by western blotting using anti-huntingtin serum raised against ... immunostaining and of the number of nuclear inclusions detected by ubiquitin and huntingtin immunostaining ), none; +, mild ⁄ occasional; ++, moderate; +++, severe ⁄ many HD-3, Huntington diseased ... substrate of this reaction to be increased in HD In extracts of the posterior brain region of control and HD mice in the presence of excess ATP, NAD+, inorganic phosphate and glucose, we determined...
- 16
- 454
- 0
catalyst design optimal distribution of catalyst in pellets, reactors, and membranes
... Arthur J Schmitt Professor in the Department of Chemical Engineering at the University of Notre Dame CAMBRIDGE SERIES IN CHEMICAL ENGINEERING Series Editor: Arvind Varma, University of Notre Dame ... species in multiple reaction systems In the case of membrane reactors additional performance indexes (e.g product purity) become of interest In deactivating systems, other indexes incorporating the ... Liang-Shih Fan and Chao Zhu, Principles of Gas-Solid Flows Hasan Orbey and Stanley I Sandler, Modeling Vapor-Liquid Equilibria: Cubic Equations of State and Their Mixing Rules T Michael Duncan and Jeffrey...
- 240
- 425
- 0
báo cáo sinh học:" The distribution and transitions of physicians in Japan: a 1974–2004 retrospective cohort study" pot
... Possible impact of changes in initial clinical training system Japan introduced a new clinical training system in 2004, and this will probably affect physicians' career choices in the future Before ... satisfied [13,14] and more inclined to change jobs [15] In Japan, HPs' working conditions, in terms of working hours, job stress and risk of lawsuits, are generally more intense than those of OPs Therefore, ... and Information Department, Ministry of Health, Labour and Welfare: Survey of Medical Practices Tokyo 2006 [in Japanese] Campbell JC, Ikegami N: The Art of Balance in Health Policy: Maintaining...
- 10
- 588
- 0
Scientific report: "The awareness of people about the risks of plant protection drugs in vegetable production: case studies in Hanoi and Thai Binh" ppsx
... was conducted in Dang Xa, Le Chi communes in Hanoi city and Thai Giang and Thuy Son in Thai Binh province Hanoi city is a major vegetable-producing region, whereas, Thai Binh province is representative ... working nearby and consumers much depend on behaviors of applicators in using pesticides The largest number 94 of respondents in all three groups perceiving of applicator pesticide risks indicates ... spraying during the last cropping season There were 46% of them in Hanoi city and 65% of those in Thai Binh province reported directly suffered from pesticide risks (Table 4) The situation of the...
- 13
- 372
- 0
Báo cáo khoa học: "Distribution of trkA in cerebral cortex and diencephalon of the mongolian gerbil after birth" docx
... age and was found in similar locations to that in brains of other kinds of murine and rat TrkA immunoreactivities were observed in newborn rat piriform cortex sections These observations indicate ... Visualization of immunobinding was carried out with DAB solution (0.04% diaminobenzidine and 0.05% H2O2 in PBS) After staining the sections were mounted on silane-coated slides (3-amino propyltriethoxy ... dictates the biological activity of NGF The biological effects of NGF are mediated via high-affinity receptor gp140trk that binds NGF and has intrinsic tyrosine protein kinase activity [14] Taken together,...
- 5
- 280
- 0
Báo cáo khoa học: "Disposition kinetics and urinary excretion of cefpirome after intravenous injection in buffalo calves" doc
... pihsralohcS tireM ytisrevinU a fo mrof eht ni ytisrevinU secneicS laminA dna yranireteV veD dagnA uruG morf deviecer ecnatsissa laicnanif eht segdelwonkca ylud rohtua roines ehT stnemgdelwonkcA ... elirets ni deraperp saw noisnepsus a dna ,h 42 rof Co73 ta oN muidem no derutluc erew smsinagro tset ehT msinagro tset eht sa )937 CCTM( gnisu ]2[ euqinhcet yassaoib lacigoloiborcim dradnats a yb ... rednu aera ;CUA ,noitartnecnoc yrotibihni muminim ;CIM :etontooF ss ,B aera snegohtap lamina nommoc tsniaga emoripfec fo noitartnecnoc yrotibihni muminim eht si ∝)nim(pC dna ,lavretni egasod eht...
- 5
- 374
- 0
Báo cáo y học: "Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureu" pot
... changes in amino acid metabolism became apparent from the flux changes for modes 35 and 154 Enzymes involved in energy and amino acid metabolism change their activity after administration of IQ-143 ... (reactions in Tables S2 and S3 in Additional file 1) of metabolism in staphylococci systematically included all pathways for which gene expression data pointed to major changes (Tables and 2) in individual ... oppositely regulated in the two strains For example, mode 122 (involving several transporter proteins for choline, carnithin and betaine) is up-regulated in S aureus but down-regulated in S epidermidis...
- 18
- 338
- 0
Báo cáo khoa hoc:" Biodegradable Nanoparticles are Excellent Vehicle for Site Directed in-vivo Delivery of Drugs and Vaccines" pptx
... Vehicle for Site Directed in- vivo Delivery of Drugs and Vaccines Anil Mahapatro1 and Dinesh K Singh2* Bioengineering Program & Department of Industrial and Manufacturing Engineering, Wichita State University, ... number of biomolecules, drugs, genes and vaccines to the site of interest in- vivo During the 1980’s and 1990’s several drug delivery systems were developed to improve the efficiency of drugs and minimize ... nanoparticles and chemical binding of the drug to the polymer can be accomplished using incorporation/adsorption techniques The amount of drugs bound to NPs and the type of interaction –between drugs and...
- 34
- 269
- 0
Báo cáo y học: " There has been a lack of investigation into the spatial distribution and clustering of suicide in Australia, where the population density is lower than " pot
... University of Technology for their input into this study Author details School of Public Health, and Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, ... level in Queensland It indicates that central Queensland, far north (part of Peninsula of Cape York), north-western areas (coastal areas of Gulf of Carpentaria), part of western, part of southern, ... study examined the spatial distribution of suicide in Queensland by gender and age Male suicides accounted for 80% of total suicide cases and 47% of total suicides were young adults In general,...
- 10
- 356
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25