... LJ: The hypothalamic- pituitary- adrenal stress axis in fibromyalgia and chronic fatigue syndrome [review] Z Rheumatol 1998, 57:67-71 40 Tsigos C, Chrousos GP: Hypothalamic- pituitary- adrenal axis, ... Wilder RL: Hypothalamic- pituitary- adrenal axis perturbations in patients with fibromyalgia Arthritis Rheum 1994, 11:1583-1592 27 Griep EN, Boersma JW, de Kloet ER: Altered reactivity of the hypothalamic- pituitary- adrenal ... cortisol levels in patients with fibromyalgia in this study It may also explain both low morning cortisol in patients with CFS and the lack of abnormalities of hormones of the HPG axis in this study...
... activation of the hypothalamic- pituitary- adrenal axis in patients with chronic fatigue syndrome J Clin Endocrinol Metab 1991, 73:1224-1234 Di GA, Hudson M, Jerjes W, Cleare AJ: 24-hour pituitary and ... steady state of the HPA axis Simulation results show the bistability in the HPA axis; a long stress forces the HPA axis to an alternate steady state (Figure 6) The HPA axis secreted cortisol in ... hormone correlates in early life: a key to HPA -axis dysregulation and normalisation Stress 2005, 8:47-57 Jacobson L: Hypothalamic- pituitary- adrenocortical axis regulation Endocrinol Metab Clin North...
... transporters in hypothalamic feedback regulation in critically ill patients is currently unknown Several mechanisms have been proposed for the suppression of the hypothalamus -pituitary- thyroid (HPT) axis ... upregulate hypothalamic D2 expression and activity [6-9] Alternatively, decreased inactivation of T3 and T4 by the type III iodothyronine deiodinase (D3) could also lead to higher hypothalamic ... which is known to artefactually alter the free fraction of thyroid hormones in the samples [23] D2 and D3 activity The complete hypothalamic block of five control animals and six prolonged ill...
... http://www.jbiomedsci.com/content/17/1/16 results indicate that administration of NaVP in pregnant mice can result in various cardiac abnormalities in fetal hearts, which is likely associated with an inhibition of histone deacetylase ... cardiac abnormality rate in the group treated with NaPV on gestation day (D7)(Table 1) Cardiac abnormalities in fetal mice exposed to NaVP showed a dose-dependent pattern with the highest rate ... examination of cardiac sections from both treated and control groups indicated that the cardiac abnormalities were characterized primarily by interventricular septal defects and by atrial septal...
... status of ARF patients using the Stewart–Figge methodology and demonstrated several features First, critically ill patients with ARF were typically acidemic compared with control patients (Fig ... critically ill patients with ARF to improve fluid overload, uremia, and acid–base disorders The use of RRT and adjustments in the replacement solutions administered to acidotic critically ill patients ... Third, in these patients there was also a marked failure to alter the apparent SID to achieve a degree of metabolic compensation (Fig 3) Despite this finding, half of the ARF patients had an...
... as exhibited by patients with chronic obstructive pulmonary disease Broad clinical experience with the application of lung protective strategies of mechanical ventilation in patients with acute ... however, as commonly occurs in mechanically ventilated patients, the effect of sodium bicarbonate may be to lower arterial pH, as was seen in patients ventilated with a lung protective strategy ... hemodynamics in 12 patients with ARDS in whom permissive hypercapnea was induced with a target CO2 of 80 mmHg Hypercapnea had the following effects on hemodynamics in control patients, in whom...
... difference Isolated abnormalities in strong ion difference and total concentration of weak acid (ATOT) From Stewart’s equations, four simple rules can be derived concerning isolated abnormalities in ... in Table illustrate an important Stewart principle Metabolic acid–base disturbances arise from abnormalities in SID and ATOT, either or both However, to quantify metabolic acid–base status at ... Acid–base effects come about 205 Critical Care April 2005 Vol No Morgan Table Rules for isolated abnormalities in strong ion difference (SID) and total concentration of weak acid (ATOT) SID/ATOT...
... Pediatric ICU patients 540 samples (282 patients) Pediatric ICU post-cardiac surgery 150 samples (44 patients) [15] Pediatric ICU, patients only with acid–base measurements 255 patients 69 (27%) ... 46 patients 42 (91%) 33 (72%) – M 39 (85%) – M 29 (63%) – M N/A [21] Adult ICU with met acidosis 50 patients 50 (100%) 49 (98%) – M,T 31 (62%) – M,T 40 (80%)– M,T N/A [28] Adult ICU with 851 patients ... specifically, there is no agreement on how to classify patients with metabolic acidosis Figure In a retrospective review of 851 ICU patients, we classified patients into categories representing the predominant...
... Results Patients There were ninety-two ICU admissions with a diagnosis of septic shock during the study period Forty patients were excluded from the study: three patients were HIV-positive, 18 patients ... admission to the ICU All the patients who died did so before day 14 The characteristics of the study patients are summarised in Table Surviving and nonsurviving patients with septic shock show ... characterised the abnormalities of the T cell compartment in septic shock and explore its clinical significance During the first 28 days of follow up circulating T lymphocytes of 52 patients with...
... excluded 211 patients who refused to participate in the study, 203 patients due to terminal illness, and another 29 patients who were receiving corticosteroid treatment Of the remaining 1,105 patients, ... Table 1: Characteristics of patients in normoglycaemia and hyperglycaemia group at initiation of follow-up All patients (N = 1,029) Patients with hyperglycaemia (N = 360) Patients without hyperglycaemia ... discharge in 76 patients in the hyperglycaemia group which led to their exclusion from the follow-up decreasing hyperglycaemia group to 360 patients The follow-up was thus initiated for 1,029 patients; ...
... GBM patients with p value of 0.86 Discussion In this study, we found that a higher percentage of PBMCs expressed p-STAT-3 in glioma patients than in healthy donors Compared to healthy donors, patients ... blood specimens from the surgical patients were obtained intraoperatively at which time all patients routinely receive dexamethasone Within this group, were patients with both the highest and ... http://www.translational-medicine.com/content/7/1/92 Figure patients Expression of p-STAT-3 is enhanced in PBMCs from glioma Expression of p-STAT-3 is enhanced in PBMCs from glioma patients PBMCs were isolated from blood...
... mir-103 (Assay n 4373158), hsa- mir-107 (Assay n 4373154) DM1 patients and control subjects have been included in this study Values of DM1 patients were compared to the medium value of control subjects ... OptiQuant image analysis software (Packard) showing miR/U6 ratios DM1 patients and controls We included in this experiment only DM1 patients showing a significant over-expression of miR-206 (DM1-1 ... http://www.translational-medicine.com/content/8/1/48 Page of Table 1: Pathohistological features of each DM1 specimens Patients Sex Muscle Lysosomal activity* Muscle pathohistological aspects DM1-1 M VL xxxx atrophy...
... IFNa2b The identification of predictive markers would permit selection of patients likely to benefit and would enable the 66% of patients unlikely to benefit to avoid the attendant toxicity The immunotherapies ... adjuvant therapy with HDI In a substudy of a large randomized trial of HDI in patients with stage IIB/III melanoma, 26% of 200 patients developed antithyroid antibodies or other autoimmune manifestations ... Additionally, in a phase I study of 19 patients receiving anti-CTLA-4 monoclonal antibody with multiple melanoma peptides and Montanide ISA 51, three of four (75%) patients with the CTLA-4 allele JO...
... breast cancer patients after primary treatment The EQ-5D was able to detect improvements and deteriorations in health and could discriminate between patients with no change in health and patients ... [10] Patients in the trial were all female, treated for breast cancer with curative intent, and had no concomitant tumors or comorbidity requiring hospital visits There were no age restrictions Patients ... the responsiveness of the EQ-5D, patients who had had their twelve months follow-up were eligible The EQ-5D and the disease-specific EORTC QLQ-C30 were sent to patients at home two weeks after...
... exoskeleton robot ARMin II Axis 1: Vertical shoulder rotation, Axis 2: Horizontal shoulder rotation, Axis 3: Internal/external shoulder rotation, Axis 4: Elbow flexion/extension, Axis 5: Pro/supination ... therapy, the WMFT scores of patients 1, and increased by +1.00, +0.5, and +0.86 points, respectively Patients and slightly diminished at follow-up Nevertheless, these three patients achieved significant ... Table None of the patients reported any adverse effects from robot-mediated therapy In contrast, patients and described reduced hardening and pain of their neck and shoulder muscles Patients 1, and...
... 0.05 in three patients (# 2,5,10) and P < 0.01 in four patients (# 1,4,6,9; Table 1) Since the quality of the blood-brain barrier has not been determined in this cohort of head-injured patients, ... of the study on CHI patients, the mean IL-18 concentrations in ventricular CSF collected up to 14 days after trauma were significantly higher than in control lumbar CSF from patients undergoing ... cerebrospinal fluid samples were significantly elevated in 50% of all head-injured patients, compared to controls (patients #1,2,3,4,6; Table 1) Elevated intracranial TNF levels after traumatic brain...
... cardiovascular, muscular skeletal, thermoregulatory and endocrine systems In some cases, menstrual abnormalities can be explained by low estrogen levels caused by a deficit in energy intake and expenditure...
... population Patients were solicited for enrollment from across Virginia, but focused on the Richmond and Tidewater areas of Virginia Patients aged 16 years and older were eligible for enrollment Patients ... SCD patients, comparison groups from published reports representing three different cohorts of patients with chronic diseases including asthma [17], cystic fibrosis [18] and hemodialysis [19] patients ... HRQOL that was equal to or poorer than patients with other significant chronic conditions in many domains Similar to patients with SCD, until somewhat recently, patients with cystic fibrosis rarely...
... obtained on all patients SDF measurements were obtained for 11 patients SDF measurements could not be obtained for all patients due to technical difficulties or safety concerns (i.e., some patients ... variables for individual patients from before and after transfusion A Recovery slopes for individual patients from before and after transfusion for full sample B NIRVO2 for individual patients from before ... deterioration in oxygen consumption in patients with preserved baseline oxygen consumption Prospective studies in ICU patients showed a higher mortality rate in patients receiving RBCs than in those...
... number of patients at serious level is low, accounting for 1.1%, the patients at extremely serious level: 0.2% Anemias extend of the researched patients before ARV treatment: 53.4% patients have ... treating services to AIDS patients in outpatient clinics for adults in studying location 3.1.2.1 Characteristics of studied patients before intervention 32.6% of AIDS patients at the age of 20-29, ... Nghe An) 0.7 patients change their regimen because of treatment failure Chart 3.7: Result of management for the researched AIDS patients After 12 months treatment ARV, the percentage of patients...