... for single marker analysis Statistical significance was assumed at p < 0.05 Statistical power (1-β) was calculated using binominal power calculation The power calculation for the -173 SNP and the ... analyzed separately as well as analyzed as a haplotype Especially inthe sub group of patients ≤60 years old and in patients with non-abdominal and non-pulmonary sepsis focus the association with poor ... polymorphism with inflammatory bowel disease in Chinese Han population Cytokine 2008, 41:44-47 Hizawa N, Yamaguchi E, Takahashi D, Nishihira J, Nishimura M: Functional polymorphisms inthe promoter...
... rs3738919 ina first sample of French Caucasian families, the same trend in replication sample 2, and again a significant association in replication sample (European Caucasian families) Finally, ... neither significant association nor linkage between SNP1 and RA in sample For SNP2, we observed a significant association for the C allele and a strong trend for a RA linkage (AFBAC, RA index cases ... disease Sample Sample (Table 1) contained the DNA from 265 European Caucasian unrelated trio families withthe same characteristics as sample 1, except for a shorter mean disease duration and a different...
... understanding in an education context is concerned with productive and valid knowledge acquisition A process that is challenging and stimulating is crucial to creating and maintaining a community ... GARRISON, ANDERSON, AND ARCHER An awareness of the critical thinking and inquiry dynamic is an essential metacognitive ability that encourages students to approach a problem strategically and actively ... possible so that teaching presence can be established and expectations can be communicated and negotiated These are but a few obvious examples of establishing appropriate teaching presence ina higher...
... between the stands inthe whole NFR and inthe Jablunkov Pass The humus layer is less acid in beech stands, but this is not the case inthe mineral soil The organic layer under beech also has a substantially ... ICP-AES as the technique of detection (Zbíral 1994) Methods of statistical analysis Exploratory statistical analysis involves the examination of mean values, coefficients of variation, maximum and ... upper-most mineral mineral mineral forest floor Horizon forest floor in comparison withthe remaining area of NFR The spatial distinctness of distribution of this element inthe Jablunkov Pass is confirmed...
... (height and maximal diameter of the trees) variables at the adult and sub-adult stage and a PCA analysis leading to two axes related to potential size and heliophily The three groups are fast growing ... N and SLA, and decreases with increasing C and LD (Tab II) It has been suggested that including additional traits related to water relations (e.g leaf conductance to water vapour) in these approaches ... species inthe glasshouse (Tab I) For more details on data collecting protocol, see Bonal et al [7] 2.5 Statistical analyses Statistical analyses were performed using SAS programs (SASInstitute, Cary,...
... coordinated the statistical analysis YM, TY and YK performed GPI ELISA TH participated in clinical assessment TS participated inthe full design and coordination of the study, and DG, SI and AT participated ... RA patients and healthy individuals P < 0.05 was considered statistically significant Results Our ELISA assay is highly specific because we used recombinant bacterial human GPI and native rabbit ... Pharmaceuticals, Osaka, Japan) was used for saturation (30 at 37°C) After two washes, sera (diluted 1/50) were added and the plates were incubated for 12 hours at 4°C After washing, alkaline phosphatase...
... stromal metaplasia Acta Otolaryngol 2004, 124:870-873 Sugai T, Oikawa M, Uesugi N, Habano W, Jiao YF, Nakamura S, Hatakeyama S, Suhara M, Hatafuku K: Esophageal squamous cell carcinoma characterized ... formation Pathol Int 2000, 50:910-913 Kijima Y, Umekita Y, Yoshinaka H, Owaki T, Sakamoto A, Yashida H, Aikou T: A case of breast carcinoma with cartilaginous and osseous metaplasia Breast Cancer 2006, ... carcinomas, such as laryngeal cancer [20], esophageal cancer [21,22], colon cancer [23-25], lung cancer [26], and breast cancer [27] The histogenesis of the osseous and/or cartilaginous metaplasia...
... polyarthritis, Rheumatoid arthritis, Insulin Resistance factor, Early inflammatory Introduction Cardiovascular disease (CVD) remains the leading cause of death in patients with inflammatory polyarthritis ... (Table 1) Factors associated with insulin resistance In an age and gender adjusted linear regression analysis, HOMA-IR was significantly associated witha number of established cardiovascular and ... TF isthe previous project lead and was involved in coordinating and supervising data collection, analysis and manuscript writing SV isthe project lead and has coordinated and supervised data...
... far In general, an association between a specific disease and an allele can be interpreted either as a causal relation or as a linkage disequilibrium between the allele and a nearby gene or a ... carina, two scans of the lower zones at cm and cm below the carina, and one at the level of the carina Scanning parameters were 1.0mm collimation, 137 kVp, 220 mA, 1.0 second scanning time, and ... statistical significance was defined as p < 0.05/k, where k isthe number of parameters for the Bonferroni correction in each set of comparisons The data were analysed withthe Statistical Package...
... stage IIIB colon carcinoma patients by clinicopathological parameters with univariate and multivariate analysis Clinicopaothological characteristics N (n = 104) 5-year survival Kaplan-Meier analysis ... Monzani E, Facchetti F, Galmozzi E, Corsini E, Benetti A, Cavazzin C, Gritti A, Piccinini A, Porro D, Santinami M, Invernici G, Parati E, Alessandri G, La Porta CA: Melanoma contains CD133 and ABCG2 ... cancer nest; (B): 5% CD133+ cells inthe cancer nest; (C) and (D): the staining of CD133 on the luminal surface and the basal surface of cancer cells; (E): the staining of CD133 on budding cancer...
... Cyclooxygenase-2 expression in advanced nasopharyngeal carcinoma -a prognostic evaluation and correlation with hypoxia inducible factor-1alpha and vascular endothelial growth factor Oral Oncol 2007, ... Weak staining for COX-2 ×200 C: Moderate staining for COX-2 ×200 D: Strong staining for COX-2 ×200 patients without COX-2 analysis data (the balance of the 221 patients), there was no significant ... Hruban R, Visavanathan K, Goggins M: Tumour COX-2 expression and prognosis of patients with resectable pancreatic cancer Cancer Biol Ther 2007, 6:1569-75 Nozoe T, Ezaki T, Kabashima A, Baba H, Maehara...
... expression data are available inthe GEO database under the ID GSE1073 Each array was print-tip normalized (mean normalized as a function of spot intensity) using the SMA package of the R statistics ... the ratio of transcipts in strain i compared to the reference pool, u isthe average ratio across all strains, Vi isthe effect of strain i on the transcript ratio, and ei isthe error An analysis ... an analysis of variance using the model yi = u + Vi + ViMj + ei where yi isthe ratio of transcipts in strain i compared to the reference pool, u isthe average ratio across all strains, Vi is...
... Stéphane Lecrom and Alexandra Louis for technical help, Fiona Francis for critical reading of the manuscript and Yoichiro Nakatani and Shinichi Morishita for providing medaka TSS mapping data This ... probably a determinant of the energetically more favorable smooth versus kinked bending of the DNA [10]; and an arginine side-chain is located inthe minor groove of all histone-DNA binding sites ... CpG islands separate transcription start sites with and without the 10-bp RR periodic signal (a, b) The 9,622 TSSs associated witha CpG island show a clear periodic signal (a) that translates into...
... hidetaji@staff.kanazawa-u.ac.jp HF: hfujita@mail.kanazawa-u.ac.jp IN: nino@staff.kanazawa-u.ac.jp TF: tphuji@staff.kanazawa-u.ac.jp TO: ohtat@staff.kanazawa-u.ac.jp pg Abstract Background: Adiponectin ... Mawatari H, Nozaki Y, Fujita K, Yoneda M, Inamori M, Nakajima N, Wada K, Nagashima Y, Nakagama H, Uozaki H, Fukayama M, Nakajima A Expression of adiponectin receptors, AdipoR1 and AdipoR2, in ... Kihara S, Sakai N, Nakajima T, Hasegawa K, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Hanafusa T, Matsuzawa Y Plasma concentrations of a novel, adipose-specific protein, adiponectin, in...
... emerging role of signal transducers and activators of transcription in cancer Nature Clin Pract Oncol 2005, 2:315-324 29 Mantovani A, Allavena P, Sica A, Balkwill F: Cancer-related inflammation Nature ... P-STAT3, (C) weak nuclear staining of STAT3, (D) weak nuclear staining of P-STAT3, (E) strong nuclear staining of STAT3, (F) strong nuclear staining of P-STAT3 Table Relationship between the STAT3 ... OS (data not shown) as reported in other studies, which confirmed our data is reliable A forward stepwise multivariate Cox model analysis, incorporating the above factors, demonstrated that the...
... course of their disease, and inoculated into the animals both at diagnosis and at relapse However, the calculation of engraftment and growth rate was based on the initially obtained sample Out ... characteristics of the leukemic blasts Competing interests ried out research data and statistics analysis and drafted the manuscript XG participated in animal experiments AJ participated in patient ... mice and inoculated into fresh animals witha similar cell dose and method used as for the first passage To determine the dissemination of human leukemia cells into distal organs of the animals,...
... Hematoxylin and Eosin (H&E) staining and mean linear intercept analysis SIRT1 deacetylase activity assay SIRT1 activity was assayed using a deacetylase colorimetric activity assay kit according ... Duquaine D, Brook RD, Aguinaldo JG, Fayad ZA, Fuster V, Lippmann M, Chen LC, Rajagopalan S: Long-term air pollution exposure and acceleration of atherosclerosis and vascular inflammation in an animal ... pentobarbital (50 mg/kg, intraperitoneally) and paralyzed with pancuronium (0.5 mg/kg, intraperitoneally) A tracheotomy was performed and an 18-guage cannula was inserted mm into an anterior nick in the...
... Hematoxylin and Eosin (H&E) staining and mean linear intercept analysis SIRT1 deacetylase activity assay SIRT1 activity was assayed using a deacetylase colorimetric activity assay kit according ... Duquaine D, Brook RD, Aguinaldo JG, Fayad ZA, Fuster V, Lippmann M, Chen LC, Rajagopalan S: Long-term air pollution exposure and acceleration of atherosclerosis and vascular inflammation in an animal ... pentobarbital (50 mg/kg, intraperitoneally) and paralyzed with pancuronium (0.5 mg/kg, intraperitoneally) A tracheotomy was performed and an 18-guage cannula was inserted mm into an anterior nick in the...