a powerful experimental system to study cell biology in live animals by intravital microscopy
Báo cáo khoa học: Trypanosoma brucei: a model micro-organism to study eukaryotic phospholipid biosynthesis docx
... but experimental evidence is lacking Interestingly, all kinetoplastid CTs are unusual fusion proteins in having a cytidylyltransferase domain fused to a CDP-alcohol phosphatidyltransferase domain ... exchange with PE involving PS synthase-2 [37] Preliminary findings in our laboratory using RNAi against a candidate gene encoding PS synthase-2 indicate that PS formation is essential for parasite ... human disorder caused by a defect in the enzyme tafazzin, which is involved in CL acyl chain remodelling in mammalian cells (reviewed in [77]) In contrast to their low abundance in eukaryotic cells,...
- 12
- 391
- 0
báo cáo hóa học: " A refined in vitro model to study inflammatory responses in organotypic membrane culture of postnatal rat hippocampal slices" potx
... well to pro and anti-inflammatory stimuli during the culture Next, we wanted to see if either proinflammatory histone deacetylase inhibitor TSA or anti-inflammatory NF-κB inhibitor helenalin could ... Sanz O, Acarin L, Gonzalez B, Castellano B: NF-kappaB and IkappaBalpha expression following traumatic brain injury to the immature rat brain J Neurosci Res 2002, 67:772-780 Hawiger J: Innate immunity ... goat anti-rabbit Alexa Fluor 488 secondary antibody (Molecular Probes) to GFAP and 1:500 diluted biotinylated rabbit anti-goat secondary (Vector BA-5000; Burlingame, CA, USA) followed by tertiary...
- 15
- 345
- 0
Báo cáo lâm nghiệp: "A decision support system to simulate and compare silvicultural scenarios for pure even-aged larch stands" doc
... rotation (45 years) and thinnings that are designed so as to maintain a constant and relatively low basal area after each cycle (15 m3 ha−1 ) The rotation of scenario is fixed to 60 years As for ... mean MOE is calculated by weighting MOEi on the basis of ring area [13] The abovementioned indicators are calculated for each scenario and the evaluations are stored in a payoff matrix SCENARIO ... scenario 3, the thinnings are designed to lead to a fixed remaining stand basal area which in this case is variable from cycle to cycle and is calculated to optimize the biodiversity indicator...
- 9
- 343
- 0
báo cáo khoa học: " A randomized controlled trial to prevent glycemic relapse in longitudinal diabetes care: Study protocol (NCT00362193)" pdf
... disparity of care between the large trials and a primary care office is largely due to the difference in resources available in the typical medical office Practical, sustainable ways of maintaining ... relapse Glycemic relapse is defined as a HbA1c greater than 8% and an increase by 1% point from baseline The primary analysis will be based on intention to treat Study Setting Telephonic intervention ... compared to a control group[38] To minimize relapse after alcohol treatment, Marlatt recommends a behavioral maintenance package consisting of identification of high-risk situations, training in...
- 9
- 361
- 0
Báo cáo khoa học: " Application of a population-based severity scoring system to individual patients results in frequent misclassification" doc
... even invariable information such as age was incorrectly abstracted or assigned to the incorrect interval that determines the score for that parameter, and that for many parameters an incorrect value ... with a summary clinical abstract, which was assumed to contain all the relevant clinical and time-line information In the clinical environment such information is frequently intimately interwoven ... calculated by Clinical Research Associates and Research Coordinators involved in a large randomized placebo-controlled critical care clinical trial We examined the effects of these scoring error rates...
- 8
- 241
- 0
Báo cáo y học: "Adoptive transfer of splenocytes to study cell-mediated immune responses in hepatitis C infection using HCV transgenic mice" pptx
... 23 Hiramatsu N, Hayashi N, Katayama K, Mochizuki K, Kawanishi Y, Kasahara A, Fusamoto H, Kamada T: Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis ... hepatitis C Hepatology 1994, 19:1354-1359 24 Mita E, Hayashi N, Iio S, Takehara T, Hijioka T, Kasahara A, Fusamoto H, Kamada T: Role of Fas ligand in apoptosis induced by hepatitis C virus infection ... Hiramatsu N, Hayashi N, Haruna Y, Kasahara A, Fusamoto H, Mori C, Fuke I, Okayama H, Kamada T: Immunohistochemical detection of hepatitis C virus-infected hepatocytes in chronic liver disease...
- 13
- 365
- 0
Báo cáo y học: " Does a new polyomavirus contribute to Merkel cell carcinoma" pot
... originbinding and helicase domains These facilitate viral replication by binding to cellular replication proteins, including Hsc70 (HSPA8), DNA polymerase, primase, topoisomerase I, and RPA (Figure ... were intact, replication initiated at an integrated origin could lead to genomic instability and cell death Indeed, in permissive cells transformed by SV40, the large T antigen is often mutated ... References Heath M, Jaimes N, Lemos B, Mostaghimi A, Wang LC, Penas PF, Nghiem P: Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features J Am Acad Dermatol...
- 4
- 247
- 0
Knowledge based expert system to minimise environmental pollution in Malaysian construction sites
... pp.237-246 Ibrahiem Abdul razak Al-Hadu PhD candidate in Civil Engineering, Universiti Tenaga Nasional, Kajang, Selangor, Malaysia His educational background in civil engineering/ water resources and environmental ... E-mail address: ibrahiem.moadmawi.ak@gmail.com Lariyah Mohd Sidek Associate Professor, Universiti Tenaga Nasional, Kajang, Selangor, Malaysia Her educational background in civil engineering/ water ... environmental management Mr Ibrahiem’s major field of study in hydrology/ urban stormwater quality management Mr Ibrahiem has earned his Mater in civil engineering from University Kebangsaan Malaysia...
- 10
- 472
- 0
Báo cáo khoa học: "A multi-staged approach to identifying complex events in textual data" ppt
... types of financial transactions they are most related to Paragraphs that did not fall into a category of interest were classified as “other” The annotated paragraphs were divided into random 4x4 ... leading us to investigate visual ways to define queries that go beyond the paragraph and span many texts over many years Finally, we are hoping to conduct user studies to validate our fundamental ... users indicate whether the paragraph is to be treated as a positive or a negative example of the category they are elaborating In our preliminary studies, we were able to achieve the peak performance...
- 4
- 404
- 0
Báo cáo khoa học: Identification of sodium salicylate as an hsp inducer using a simple screening system for stress response modulators in mammalian cells pptx
... effect mediated by suppression of the production of in ammatory mediators by inhibition of cyclooxygenase and nuclear factor-kappa B activation [9,10] In addition to the anti -in ammatory effects, ... various mammalian cells Enhancement of thermoresistance of cells by SA Upon exposure to a sublethal heat treatment, mammalian cells acquire transient resistance to a subsequent heat shock that would ... Alzheimer’s, polyglutamine and Parkinson’s disease are though to be caused by an accumulation of protein aggregates in the brain [24], and Hsps such as Hsp70 and Hsp40 are shown to suppress the toxicity...
- 8
- 470
- 0
A Decade Of Aid To The Health Sector In Somalia 2000-2009 docx
... and inefficient Innovative systems to be er link local authorities to national and international partners need to be identified (such as creation of a Health System Analysis Team, as advocated by ... Aid Financing Total health sector aid financing to Somalia grew from US$23 million in 2000 to US$103 million in 2009 (Table 4.1), almost a fivefold increase in 10 years Data show an increasing trend ... increases in ODA; 10 fragile states have seen lower ODA levels in 2008 in real terms compared with 2000 (Angola, Equatorial Guinea, Eritrea, Guinea, Guinea-Bissau, Papua New Guinea, São Tomé and Príncipe,...
- 68
- 486
- 0
Báo cáo khoa học: Targeted disruption of one of the importin a family members leads to female functional incompetence in delivery docx
... 34 Tanaka N, Espey LL, Stacy S & Okamura H (1992) Epostane and indomethacin actions on ovarian kallikrein and plasminogen activator activities during ovulation in the gonadotropin-primed immature ... blotting apparatus (Horizblot; ATTO, Tokyo, Japan) Molecular mass markers (Precision Plus Protein Standards; Bio-Rad Laboratories, Hercules, CA, USA; Magic Mark XP, Invitrogen, Carlsbad, CA, USA) ... intraperitoneally injected with IU of PMSG (Serotropin; ASKA Pharmaceutical, Tokyo, Japan), and induced to ovulate after 48 h with IU of hCG (Gonatropin; ASKA Pharmaceutical) Thirteen hours after...
- 12
- 346
- 0
A systems-based approach to assessing leadership styles in engineers
... Text Mining Text mining is an “area within data mining that focuses on data from textual sources” (Feldman, 2003; Ye, 2003) Text mining is a large subfield of data mining It is an area that has developed ... learning It makes generalizations by “producing reasonable outputs for inputs not encountered during training or learning” (Haykin, 1999) A Backpropagation network is capable of adapting to its ... training backpropagation is to achieve a balance between the ability to respond correctly to the input patterns that are used for training and the ability to give reasonable responses to input that...
- 183
- 331
- 0
báo cáo sinh học:" Development of a quality assurance handbook to improve educational courses in Africa" docx
... medical training institution in Ghana, in addition to having it reviewed by independent experts in higher education The principles outlined in the handbook help to provide a regulatory framework to ... Medicine is involved in delivering off-site higher-educational programmes to health care workers in Africa Our colleagues at one of these sites, a teaching hospital in Kumasi, Ghana, West Africa, ... clearly defined penalties for plagiarism and collusion Quality assurance of approval and review processes Aim To maintain the academic quality of courses and ensure that courses remain relevant in the...
- 5
- 488
- 0
Báo cáo hóa học: " Pyrosequencing of 16S rRNA gene amplicons to study the microbiota in the gastrointestinal tract of carp (Cyprinus carpio L.)" doc
... Cyanobacteria Actinobacteria Chlamydiales Bacteria Simkaniaceae Parachlamydiaceae Fusobacteriales Fusobacteriaceae Opitutae Verrucomicrobia Verrucomicrobiaceae Spartobacteria Sphingobacteriales ... Brachymonas Diaphorobacter Variovorax uncultured Comamonadaceae Aeromonas Shewanella Gammaproteobacteria B38 Gammaproteobacteria aaa3 4a1 0 Pseudospirillum Acinetobacter Aquicella Legionella Listonella ... Brocadia anammoxidans Candidatus Brocadia fulgida Candidatus Jettenia Candidatus Kuenenia Phycisphaerae OM190 Planctomycetes Asahi BRW2 Planctomycetes BD7 11 Planctomycetes vadinHA49 Phycisphaerae...
- 9
- 463
- 0
Báo cáo hóa học: " Research Article A Dual Decomposition Approach to Partial Crosstalk Cancelation in a Multiuser DMT-xDSL Environment" docx
... the average capacity increase for allocating less or equal crosstalk cancellation taps than rs is set to zero, (ii) the average capacity increase for allocating more crosstalk cancellation taps ... the average capacity increases per allocated crosstalk cancellation tap For each of K tones the capacity increase has to be calculated for all N − crosstalk cancellation configurations To be able ... be allocated to that user In order to this, the average benefit of adding a crosstalk cancellation tap for that user is increased by a factor ωn A larger weight leads to more crosstalk cancellation...
- 11
- 400
- 0
Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 1) ppt
... creating ES cell lines that are genetically identical to the patient It may also be possible to derive pluripotent stem cells from spermatogonia in the adult human testis, providing another strategy ... differentiating them into nonhematopoietic phenotypes are largely lacking The quantity of cells from any single source can also be limiting Organ-specific multipotent stem cells are already somewhat ... brain), and somatic stem cells capable of generating cell types specific for the target rather than the donor organ (e.g., bone marrow mesenchymal stem cells for cardiac repair) (Chap 66) ES cells...
- 5
- 456
- 0
Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 2) pps
... cell delivery is not yet clear, and various experimental studies have employed intramyocardial, transendocardial, intravenous, and intracoronary injections In experimental myocardial infarction, ... Bone marrow stem cells in particular have been examined in clinical trials of human ischemic heart disease These have largely been small, nonrandomized studies that typically combine cell treatment ... them to "home" into the damaged tissue; (2) in vitro differentiation of stem cells followed by transplantation into a damaged organ—e.g., pancreatic islet cells could be generated from stem cells...
- 5
- 316
- 0
Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 3) pot
... abortuses are an alternative, and a clinical trial of fetal neural stem cells in Batten disease is commencing Transdifferentiation of bone marrow and adipose stem cells into neural stem cells, and ... Multipotential stem cells also reside within gastric glands and intestinal crypts Thus, hepatic, pancreatic, and/or gastrointestinal precursor cells may be candidates for cell- based therapy of diabetes ... the pancreas, liver, and gastrointestinal tract are all derived from the anterior endoderm, and transdifferentiation of the pancreas to liver and vice versa has been observed in certain pathologic...
- 5
- 365
- 0
Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 4) pot
... organ Imaging techniques are needed to visualize stem cells in vivo after transplantation into humans Fortunately, stem cells can be engineered before transplantation to contain contrast agents ... extraordinary, and disorders such as myocardial infarction, diabetes, Parkinson's disease and many others are attractive targets However, such stem cell based therapies are at a very early stage ... coadministration of scaffolding, artificial extracellular matrix, and/or growth factors to orchestrate differentiation of stem cells and their organization into appropriate constituents...
- 5
- 311
- 0
Tìm thêm: xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose