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9 roles of o fucosyltransferase 1 and o linked fucose in notch receptor function

The roles of histone deacetylases 1 and 2 in hepatocellular carcinoma

The roles of histone deacetylases 1 and 2 in hepatocellular carcinoma

Cao đẳng - Đại học

... functions of HDAC1 and 18 1 .9. 1 Redundancy of HDAC1 and HDAC2 functions 18 1 .9. 2 Distinct functions of HDAC1 and HDAC2 19 1. 10 Inhibition of HDAC 20 1. 11 Biological ... 5.5 Role of enzyme activity in function of HDAC1 and 11 8 5.5 .1 Synergistic reduction of HDAC activity after HDAC1 and knockdown 11 8 Effect of knocking down HDAC1 and on colony formation is ... specificity and efficiency of HDAC1 and HDAC2 knockdown 71 Figure 4 .9 Knockdown of protein expression of HDAC1 or /and HDAC2 in HEP3B, HEPG2, PLC5, and HCT 116 cells 73 Figure 4 .10 Effect of knocking down...
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Báo cáo khoa học: Roles of prolactin-releasing peptide and RFamide related peptides in the control of stress and food intake potx

Báo cáo khoa học: Roles of prolactin-releasing peptide and RFamide related peptides in the control of stress and food intake potx

Báo cáo khoa học

... ( 19 9 1) Brain oxytocin receptor antagonism blunts the effects of anorexigenic treatments in rats: evidence for central oxytocin inhibition of food intake Endocrinology 1 29, 785– 7 91 18 Blevins ... Potent action of RFamide-related peptide-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion Endocrinology 1 49, 5 811 –58 21 Kadokawa ... serotonin play major roles in the control of food intake and stress responses The physiological functions of these receptors expressed in RFRP neurons remain to be determined PrRP and RFRPs in...
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báo cáo khoa học:

báo cáo khoa học: " Roles of arabidopsis WRKY18, WRKY40 and WRKY60 transcription factors in plant responses to abscisic acid and abiotic stress" doc

Báo cáo khoa học

... transfer using the NIH ImageJ1. 41 program Cloning, expression, purification of recombinant proteins and the EMSA Cloning, expression in E coli and purification of recombinant WRKY 18 and 40 proteins ... responses Figure 10 Proposed model for involvement of WRKY18, WRKY40 and WRKY60 in ABA responses ABA induction of WRKY18 and WRKY40 leads to increase in WRKY18 and WRKY40 proteins that form both ... before transfer to 23°C for germination and growth For tests of the ABA effect on germination, seeds were plated directly onto media containing various concentrations of ABA For testing root elongation...
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Báo cáo Y học: Structural and serological relatedness of the O-antigens of Proteus penneri 1 and 4 from a novel Proteus serogroup O72 pptx

Báo cáo Y học: Structural and serological relatedness of the O-antigens of Proteus penneri 1 and 4 from a novel Proteus serogroup O72 pptx

Báo cáo khoa học

... indole negative or as Proteus vulgaris biogroup J Clin Microbiol 15 , 1 097 11 02 List 11 ( 19 8 3) Validation of the publication of new names and new combinations previously e€ectively published outside ... penneri O- antigen glucosylation and O- acetylation are postpolymerization modi®cations [22] Serological studies Lipopolysaccharides from 38 strains of P penneri and 65 strains from 49 O- serogroups of ... for pyranose rings Org Magn Reson 13 , 417 ±4 29 19 Bock, K & Pedersen, C ( 19 7 4) A study of 13 CH coupling constants in hexopyranoses J Chem Soc Perkin Trans 2, 293 ± 297 20 Lipkind, G.M., Shashkov,...
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báo cáo khoa học:

báo cáo khoa học: " FCR (Fludarabine, Cyclophosphamide, Rituximab) regimen followed by 90yttrium ibritumomab tiuxetan consolidation for the treatment of relapsed grades 1 and 2 follicular lymphoma: a report of 9 cases" pot

Báo cáo khoa học

... responding to FCR regimen and consolidated with 90 Y-RIT obtained a significant high rate of response with 10 0% of CR and acceptable toxicity After a median observation period of 34 months 6 /9 ... received cycles of FCR: fludarabine at a dose of 25 mg/m2 i.v on days to 3; cyclophosphamide at a dose of gr/m2 i.v on day and rituximab Page of at a dose of 375 mg/m2 was given on day of each cycle ... number was between 10 0 × 1 09/ L and 1 49 × 1 09/ L, not to exceed a total of 1. 184 MBq administered as a slow i.v push over 10 minutes (Figure 1) Assessments All patients included in the analysis were...
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Tài liệu Báo cáo khoa học: Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin-induced cell detachment and apoptosis docx

Tài liệu Báo cáo khoa học: Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin-induced cell detachment and apoptosis docx

Báo cáo khoa học

... characterization of the kringle fragment of human plasminogen J Biol Chem 256, 11 166 11 1 71 Cummings HS & Castellino FJ ( 19 8 5) A monoclonal antibody to the epsilon-aminocaproic acid binding site on the kringle ... 265, 610 4– 611 1 19 Tulinsky A, Park CH, Mao B & Llinas M ( 19 8 8) Lysine ⁄ fibrin binding sites of kringles modeled after the structure of kringle of prothrombin Proteins 3, 85 96 20 Thorsen S ( 19 7 5) ... the binding of antifibrinolytic amino acids to various plasminogens Arch Biochem Biophys 15 1, 19 4 – 19 9 Castellino FJ, Brockway WJ, Thomas JK, Liano HT & Rawitch AB ( 19 7 3) Rotational diffusion analysis...
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Tài liệu Báo cáo khoa học: Proton transfer in the oxidative half-reaction of pentaerythritol tetranitrate reductase Structure of the reduced enzyme-progesterone complex and the roles of residues Tyr186, His181 and His184 pdf

Tài liệu Báo cáo khoa học: Proton transfer in the oxidative half-reaction of pentaerythritol tetranitrate reductase Structure of the reduced enzyme-progesterone complex and the roles of residues Tyr186, His181 and His184 pdf

Báo cáo khoa học

... Reaction of morphinone reductase with 2-cyclohexen -1- one and 1- nitrocyclohexene: proton donation, ligand binding, and the role of residues Histidine 18 6 and Asparagine 1 89 J Biol Chem 280, 10 695 – 10 7 09 ... Barsukov I & Scrutton NS (2005) Reaction of morphinone reductase with 2-cyclohexen -1- one and 1- nitrocyclohexene: proton donation, ligand binding and the role of residues His186 and Asn -1 89 J Biol ... (gradient of 15 15 0 mm NaCl contained in L buffer A) to obtain pure protein Redox potentiometry, ligand binding and stopped-flow kinetic analyses Redox titrations and the determination of redox potential...
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Tài liệu Báo cáo Y học: Binding of gelsolin domain 2 to actin An actin interface distinct from that of gelsolin domain 1 and from ADF/cofilin pptx

Tài liệu Báo cáo Y học: Binding of gelsolin domain 2 to actin An actin interface distinct from that of gelsolin domain 1 and from ADF/cofilin pptx

Báo cáo khoa học

... Hawkins, M., Pope, B & Way, M ( 19 9 1) Role of actin-binding proteins in cytoskeletal dynamics Biochem Soc Trans 19 , 10 16 10 20 43 Southwick, F.S ( 19 9 5) Gain -of- function mutations conferring actin-severing ... the complex by V8 protease or on cross-linking of the 1 59 19 3 peptide to actin after digestion by thrombin Digestion of actin by V8 protease gives two major fragments [ 19 ] of 31 and 16 kDa (1 –225 ... reported in Fig 8A indicate that only peptide 1 19 13 2 interacted with a Kd of 2 .9 mM The binding of the 1 19 13 2 peptide was confirmed in solution To perform such an experiment gelsolin 1 59 19 3 ...
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Báo cáo khoa học: Respective roles of the catalytic domains and C-terminal tail peptides in the oligomerization and secretory trafficking of human acetylcholinesterase and butyrylcholinesterase potx

Báo cáo khoa học: Respective roles of the catalytic domains and C-terminal tail peptides in the oligomerization and secretory trafficking of human acetylcholinesterase and butyrylcholinesterase potx

Báo cáo khoa học

... also formed homotetramers However, introduction of a cysteine at the homologous position in Bb (Bb19C) only produced approximately 30% of tetramers, and this proportion was not significantly increased ... FG ( 19 8 8) Sequential activation of butyrylcholinesterase in rostral half somites and acetylcholinesterase in motoneurones and myotomes preceding growth of motor axons Development 10 2, 387– 396 ... approximately mm acetylthiocholine The rates of hydrolysis of acetylthiocholine and butyrylthiocholine (at mm) by BChE were approximately 14 % and 24% of the rate of hydrolysis of acetylthiocholine...
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Báo cáo khoa học: Inhibitors of protein phosphatase 1 and 2A decrease the level of tubulin carboxypeptidase activity associated with microtubules pptx

Báo cáo khoa học: Inhibitors of protein phosphatase 1 and 2A decrease the level of tubulin carboxypeptidase activity associated with microtubules pptx

Báo cáo khoa học

... Capability of tubulin and microtubules to incorporate and to release tyrosine and phenylalanine and the effect of the incorporation of these amino acids on tubulin assembly J Neurochem 31, 205– 210 Arce, ... phosphorylation/dephosphorylation events are clearly involved in association of carboxypeptidase with microtubules in living cells Phosphorylation/dephosphorylation of tubulin carboxypeptidase (or an intermediary ... ( 19 8 8) Post-transla˜ tional tyrosination/detyrosination of tubulin and microtubules Mol Neurobiol 2, 13 3 15 3 Hallak, M.E., Rodriguez, J.A., Barra, H.S & Caputto, R ( 19 7 7) Release of tyrosine from...
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báo cáo hóa học:

báo cáo hóa học:" Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a" pot

Hóa học - Dầu khí

... 0.00 016 6 C19orf 59 chromosome 19 open reading frame 59 (C19orf 59) 3.33 0. 01 39 ZFYVE 21 zinc finger, FYVE domain containing 21 (ZFYVE 21) 3.32 0.00362 CCR1 chemokine (C-C motif) receptor (CCR1) 3 .14 0.000335 ... 89, 954 13 1,558 ± 35, 298 21. 0 ± 13 .0 61. 1 ± 7.5 473 .1 ± 2 39 11 .1 ± 6.5 10 ,467,524 ± 7, 793 , 493 1, 672 ± 854 93 .5 ± 27.8 1, 1 81 ± 1 0 91 8,4 21 ± 2,684 93 0 , 91 6 ± 650,0 21 527, 593 ± 45 ,14 17 338 ± 330 1 09. 0 ... ARL10 ADP-ribosylation factor-like 10 (ARL10) 2. 79 6.80 × 10 -3 RPS28 ribosomal protein S28 (RPS28) 2.76 1. 28 × 10 -4 C15orf 29 chromosome 15 open reading frame 29 (C15orf 29) 2.76 9. 34 × 10 -3 C20orf 19 9 ...
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Báo cáo sinh học:

Báo cáo sinh học: "Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study" pptx

Hóa học - Dầu khí

... al Journal of Translational Medicine 2 011 , 9: 23 http://www.translational-medicine.com/content /9/ 1/ 23 Page of Time-course of sFlt -1 and VEGF-A expression in FN At the time of fever onset no statistical ... determinant of sepsis morbidity and mortality J Exp Med 2006, 203 :14 47 -14 58 Page of 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 Shapiro N, Schuetz P, Yano K, Sorasaki M, Parikh SM, Jones AE, ... maintain endothelial barrier in patients of the latter group In animal models of sepsis, overexpression of sFlt -1 was capable to completely block the barrier-breaking effects of VEGF-A and to...
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báo cáo hóa học:

báo cáo hóa học:" Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study" pdf

Hóa học - Dầu khí

... al Journal of Translational Medicine 2 011 , 9: 23 http://www.translational-medicine.com/content /9/ 1/ 23 Page of Time-course of sFlt -1 and VEGF-A expression in FN At the time of fever onset no statistical ... determinant of sepsis morbidity and mortality J Exp Med 2006, 203 :14 47 -14 58 Page of 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 Shapiro N, Schuetz P, Yano K, Sorasaki M, Parikh SM, Jones AE, ... maintain endothelial barrier in patients of the latter group In animal models of sepsis, overexpression of sFlt -1 was capable to completely block the barrier-breaking effects of VEGF-A and to...
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Báo cáo toán học:

Báo cáo toán học: "Graphs Associated with Codes of Covering Radius 1 and Minimum Distance 2" ppsx

Báo cáo khoa học

... number of colours of G and the size and number of connected components of Gα cannot be any larger than that of G or Gα Now we are ready for the proof of Theorem P1 The vertices of G and words of ... columns and the symbols in L corresponds to permuting the symbols in each of the positions in C; permutation on the set {row, column, symbol} corresponds the electronic journal of combinatorics 15 ... G Cohen, I Honkala, S Litsyn, and A Lobstein Covering Codes North Holland, 19 9 7 [3] C J Colbourn, J H Dinitz, and I M Wanless Handbook of combinatorial designs, chapter Latin Squares, pages 13 5 15 1...
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Báo cáo y học:

Báo cáo y học: "Regulation of pathogenic IL-17 responses in collagen-induced arthritis: roles of endogenous interferon-gamma and IL-4" pot

Báo cáo khoa học

... Miossec P: The combination of tumor necrosis factor alpha blockade with interleukin -1 and interleukin -17 blockade is more effective for controlling synovial inflammation and bone resorption in ... ex vivo model Arthritis Rheum 20 01, 44 :1 293 -13 03 Page 13 of 15 (page number not for citation purposes) Arthritis Research & Therapy 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Vol 11 No Sarkar ... signals modulate trafficking of Th17 cells to the joint, either by altering expression of chemokines by cells of the synovium or expression of chemokine receptors by T cells Once in the joint, Th17...
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Báo cáo y học:

Báo cáo y học: " Molecular characterization of genome segments 1 and 3 encoding two capsid proteins of Antheraea mylitta cytoplasmic polyhedrosis virus" pps

Báo cáo khoa học

... 7 :18 1 http://www.virologyj.com/content/7 /1/ 1 81 Page 11 of 11 40 Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye ... both forward and reverse directions S1 consisted of 3852 nucleotides with one long ORF of 3735 nucleotides and could encode a protein of 12 45 amino acids with molecular mass of ~14 1 kDa (p1 41) Thirty ... shown in parenthesis Chakrabarti et al Virology Journal 2 010 , 7 :18 1 http://www.virologyj.com/content/7 /1/ 1 81 Page of 11 Analysis of recombinant AmCPV S1 and S3 encoded proteins expressed in E coli...
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Báo cáo y học:

Báo cáo y học: "Transcriptional regulation of matrix metalloproteinase-1 and collagen 1A2 explains the anti-fibrotic effect exerted by proteasome inhibition in human dermal fibroblasts" docx

Báo cáo khoa học

... in binding of SP1, but not Page of 14 of AP2, to the promoter region of COL1A2 in response to TGF-β (Figure 2c) Thus, the coordinated increase in COL1A1 and COL1A2 gene transcription in response ... Page of 14 Figure Proteasome inhibition abolishes the increased binding of SP1 to COL1A2 but not of AP2 to COL1A1 promoter induced by TGF-β (a) Schematic representation of the COL1A1 and COL1A2 ... proximal AP -1 binding site of the MMP -1 promoter On the other hand, we have shown that inhibition of SP1 binding to the promoter of COL1A2 correlates with decreased COL1A2 transcription in both...
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Báo cáo khoa học:

Báo cáo khoa học: " Herpes simplex virus type 1 and normal protein permeability in the lungs of critically ill patients: a case of low pathogenicity" docx

Báo cáo khoa học

... directly to the microbiology laboratory or placed in viral transport medium (Copan Diagnostics Inc., Corona, CA, USA) For isolation of HSV -1, specimens were inoculated using standard procedures in triplicate ... characteristics, and outcome in immunocompromised and nonimmunocompromised hosts Am J Med 19 9 3, 94 : 293 3 Klainer AS, Oud L, Randazzo J, Freiheiter J, Bisaccia E, Gerhard H: Herpes simplex virus involvement of ... lungs, or by the presence of giant cells or nuclear inclusion bodies on cytology or biopsy of the lower respiratory tract [3,5 ,9, 10 ,18 ] Indeed, Tuxen and coworkers [4] observed that prophylactic...
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Báo cáo y học:

Báo cáo y học: "High systemic levels of interleukin-10, interleukin22 and C-reactive protein in Indian patients are associated with low in vitro replication of HIV-1 subtype C viruses" docx

Báo cáo khoa học

... Interleukin 10 blocks HIV replication in macrophages by inhibiting the autocrine loop of tumor necrosis factor alpha and interleukin induction of virus AIDS Res Hum Retroviruses 19 9 4, 10 :1 19 9 -12 06 ... sequencing and were shown to belong to HIV-1C, the subtype predominant in 99 % of infections in India [ 39] Thirty isolates were also subtyped in the pro and gag genomic regions and shown to belong to ... infection (MOI) of 0.0 01 and monitoring for p24 production over a period of 12 days post-infection (p.i.) The virus stock was diluted to obtain a MOI of 0.0 01 IU/PBMC, based on the TCID50 (IU/ml) of...
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Báo cáo y học:

Báo cáo y học: "The roles of binding site arrangement and combinatorial targeting in microRNA repression of gene expression" ppt

Báo cáo khoa học

... nucleobase, nucleoside, nucleotide and nucleic acid metabolism 51 30 . 91 5.55E -12 Biological Process Homophilic cell adhesion 15 9. 09 1. 82E -11 Biological Process Transcription 51 30 . 91 1 .96 E -11 Biological ... binding protein KIAA02 61 40 NM_ 015 045 Kiaa02 61 RNF38 40 NM_0227 81 Ring finger protein 38 BAZ2A 39 NM_ 013 4 49 Bromodomain adjacent to zinc finger domain, 2A CBFA2T3 39 NM _17 593 1 Core-binding factor, ... Biological Process Regulation of cellular metabolism 54 32.73 9. 26E -11 Biological Process Nervous system development 23 13 .94 1. 49E -10 Biological Process Regulation of metabolism 54 32.73 1. 71E -10 ...
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