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870 893 and comparison to concentrations achieved in cancer patients at the cp 870 893 maximum tolerated dose

Báo cáo khoa học:

Báo cáo khoa học: "Ultrasound-guided central venous catheterization in cancer patients improves the success rate of cannulation and reduces mechanical complications: A prospective observational study of 1,978 consecutive catheterizations" pps

Báo cáo khoa học

... 1,978 (97.6%) of the catheters inserted The absence of pneumotorax and other major complications indicates that US guidance should be mandatory for CVC insertion in patients with cancer Background ... essential in patients with cancer, and the need for intravenous access devices for the administration of cancer therapy has increased proportionally with the increasing number of patients diagnosed ... needle is introduced into the last portion of internal jugular vein This vein was reached through the transducer placed at the point of insertion of the sternocleidomastoid muscle into the clavicular;...
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The impact of and responses to HIV/AIDS in the private security and legal services industry in South Africa potx

The impact of and responses to HIV/AIDS in the private security and legal services industry in South Africa potx

Ẩm thực

... employed and trained Training was conducted at the HSRC in Pretoria from 31 May to June 2006 Twelve trainers took part, and they represented the HSRC, the laboratory and couriers The training content ... development To identify appropriate measures and indicators, the process that was followed ensured that: international measures and indicators were replicated in the survey; additional measures and indicators ... of the entire workforce in this large, multinational mining organisation operating in the Gauteng, Limpopo and North West provinces of South Africa Further, there is growing evidence that the...
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báo cáo hóa học:

báo cáo hóa học:" Pain in cancer. An outcome research project to evaluate the epidemiology, the quality and the effects of pain treatment in cancer patients" pptx

Hóa học - Dầu khí

... conduct and supervision In order to be able to conduct and monitor the progress of the trial for the patients' safety and according to the World Medical Association Declaration of Helsinki and the ... of the eligibility and inclusion in the study, the investigator will assign treatments to patients according to the standard practice (usual care) In the case of prescription of WHO step-II and ... analgesic-drug therapy: Patient Management index (PMI), categorized in a binary variable according to negative (indicating inadequate analgesic care) and positive (conservative indicator of acceptable treatment)...
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Báo cáo toán học:

Báo cáo toán học: " [18F]CFT synthesis and binding to monoamine transporters in rat" pdf

Toán học

... proteins located in the dopaminergic nerve terminals; they regulate the synaptic concentration of dopamine in the brain Changes in the density and function of DAT in the brain are involved in many ... set of data, and in drafting the manuscript MH has contributed in the concept and design of the study, in acquiring data, in analyzing and interpreting data, and in drafting the manuscript and has ... acquiring the dosimetric data, in analyzing and interpreting this set of data, and in drafting the manuscript TG has contributed in acquiring the preclinical data, in analyzing and interpreting this...
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Báo cáo y học:

Báo cáo y học: "The ITGAV rs3738919 variant and susceptibility to rheumatoid arthritis in four Caucasian sample sets" pptx

Báo cáo khoa học

... autoimmune disease The 713 UK patients were recruited in Oxford, with informed consent from attendees at the rheumatology outpatient clinic at the Nuffield Orthopaedic Centre All fulfilled the ... transducer and activator of transcription (STAT4) [9], the tumour necrosis factor receptor-associated factor region (TRAF/C5) [7,10,11] and CD40, CCL21 and IL2RB [12,13] The integrin ανβ3 (ITGAV) ... established, with many other loci also incriminated These include the protein tyrosine phosphatase non-receptor 22 (PTPN22) gene [4,5], cytotoxic Tlymphocyte antigen (CTLA4) [6], an intergenic region...
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Báo cáo sinh học:

Báo cáo sinh học: "Nomenclature for naming loci, alleles, linkage groups and chromosomes to be used in poultry genome publications and databases" ppsx

Báo cáo khoa học

... This outline is aimed at suggesting nomenclature for use in journal publications and in the international chicken genome database (CHICKBASE) being developed at the Roslin Institute (Edinburgh), ... maintains the Linkage and diploid nature of the symbol.) phase Horizontal lines or slashes separate alleles and indicate chromosome location Loci not located on the same chromosome are separated ... CHROMOSOMAL AND PHYSICAL MAPPING NOMENCLATURE banding nomenclature was discussed at the North American Colloquium Cytogenetics and Gene Mapping held in Guelph, ON, 13-16 banding nomenclature for the...
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Báo cáo y học:

Báo cáo y học: " Pre-treatment mortality and loss-to-follow-up in HIV-1, HIV-2 and HIV-1/HIV-2 dually infected patients eligible for antiretroviral therapy in The Gambia, West Africa" doc

Báo cáo khoa học

... of patients who start and remain on treatment The aim of this analysis is to investigate pre-treatment loss to follow-up and to determine mortality rates and predictors of mortality among HIV infected ... treatments, including antiretroviral therapy, and treatment monitoring are provided free of charge and the patients also receive reimbursement of their transport cost to and from the clinic at ... dying before starting treatment among ART-eligible patients could therefore be attributed more to the operational delivery system and policies that result in delay in access to ART The finding...
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Báo cáo y học:

Báo cáo y học: "Users'''' perspectives of barriers and facilitators to implementing EHR in Canada: A study protocol" pot

Báo cáo khoa học

... provincial initiatives, to create and implement EHR [59] However, in spite of these initiatives, significant gaps remain in understanding the challenges related to developing, implementing, and ... patients and the public in general regarding an interoperable EHR have rarely been addressed and deserve specific attention EHR and patients and public participation As the role of patients in ... in implementing EHR The project is divided into two main phases that will allow: reviewing and synthesizing relevant literature on barriers and facilitators to implementing the EHR that are perceived...
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báo cáo khoa học:

báo cáo khoa học: " Implementing and evaluating a regional strategy to improve testing rates in VA patients at risk for HIV, utilizing the QUERI process as a guiding framework: QUERI Series" pptx

Báo cáo khoa học

... the HIV testing rate will be done to adjust for the covariates at patient, provider, and sub-station levels – and for clustering We have obtained information regarding all inpatient and outpatient ... notification [43] Implementation The intervention program is being put in place for one year in the primary care clinics of stations A and B in VISN 22 The three remaining stations in VISN 22 (stations ... agreed to make HIV testing a performance monitor, to support installation of the HIV Testing Clinical Reminder, and to participate as full partners in enhancing station accountability After obtaining...
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báo cáo khoa học:

báo cáo khoa học: " Users'''' perspectives of barriers and facilitators to implementing EHR in Canada: A study protocol" potx

Báo cáo khoa học

... provincial initiatives, to create and implement EHR [59] However, in spite of these initiatives, significant gaps remain in understanding the challenges related to developing, implementing, and ... patients and the public in general regarding an interoperable EHR have rarely been addressed and deserve specific attention EHR and patients and public participation As the role of patients in ... in implementing EHR The project is divided into two main phases that will allow: reviewing and synthesizing relevant literature on barriers and facilitators to implementing the EHR that are perceived...
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báo cáo khoa học:

báo cáo khoa học: " Implementing and evaluating a regional strategy to improve testing rates in VA patients at risk for HIV, utilizing the QUERI process as a guiding framework: QUERI Series" docx

Báo cáo khoa học

... the HIV testing rate will be done to adjust for the covariates at patient, provider, and sub-station levels – and for clustering We have obtained information regarding all inpatient and outpatient ... notification [43] Implementation The intervention program is being put in place for one year in the primary care clinics of stations A and B in VISN 22 The three remaining stations in VISN 22 (stations ... agreed to make HIV testing a performance monitor, to support installation of the HIV Testing Clinical Reminder, and to participate as full partners in enhancing station accountability After obtaining...
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Báo cáo y học:

Báo cáo y học: "Persistence and compliance to antidepressant treatment in patients with depression: A chart review" doc

Báo cáo khoa học

... conducted the first study that investigates persistence and compliance to antidepressants in patients with a major depressive disorder in the clinical outpatient setting Notwithstanding the limitations ... appropriate instructions to patients Elwyn et al suggested that the involvement of patients in shared decision making is one of the key components of enhancing adherence [23] Combined with the findings ... persistence and poor compliance to antidepressant treatment were found to be problematic in patients with depression in the clinical outpatient setting Porer compliance to medications in patients...
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Báo cáo y học:

Báo cáo y học: " Responses of FEV6, FVC, and FET to inhaled bronchodilator in the adult general population" ppt

Báo cáo khoa học

... Linda, CA, USA) The beginning point of measurement is the back extrapolated time zero [14,25] and the end-point at the beginning of the end-expiratory plateau In cases where the total exhalation ... population (n and FVC, to the ratio of forced expiratory volume in the The relationship a) at the baseline in in forced vital capacity (FVC) 628) second The relationship of a) individual changes in ... hypothesized that in patients with chronic airflow limitation combined with hyperinflation the potential increase of expiratory airflow due to bronchodilation may be attenuated in small airways due to airway -to- parenchymal...
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Báo cáo y học:

Báo cáo y học: "Bench-to-bedside review: Significance and interpretation of elevated troponin in septic patients" ppt

Báo cáo khoa học

... troponin T, which binds to tropomyosin and facilitates contraction; troponin I, which binds to actin and inhibits actin-myosin interactions; and troponin C, which binds to calcium ions [2,6] The ... proteins, it has been suggested that cytosolic pools of these proteins are released into the circulation after cell injury The cytosolic pool for cardiac troponin T was estimated at 6% to 8% of total ... motifs The existence of such cleavage sites explains the findings that exposure of myofibrillar proteins to active caspase results in α-actin, α-actinin and troponin T and myosin light chain cleavage...
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Báo cáo y học:

Báo cáo y học: "Violence against civilians and access to health care in North Kivu, Democratic Republic of Congo: three cross-sectional survey" docx

Báo cáo khoa học

... thresholds in our surveys, the proportion of violent death was high, reaching over 30% in the global population in two sites and 58% and 71% in the population years and over in the same sites While the ... interpretation of the study and wrote the paper; EG, YCL, and JP participated in the design of the study, analysis and interpretation of data, and revising the paper critically for substantial intellectual ... being lower than that reported in other surveys, and demonstrate that high disease-related mortality rates are not inevitable The exposure of the population to violence is also revealed in the...
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Báo cáo y học:

Báo cáo y học: "Molecular model of the outward facing state of the human P-glycoprotein (ABCB1), and comparison to a model of the human MRP5 (ABCC5)" docx

Báo cáo khoa học

... inside of the membrane, binding with high affinity to the binding site, to the outside of the membrane, binding with low affinity, and thus being expelled to the extracellular space [44] It is therefore ... (%) of the charged amino acids aspartate (D), glutamate (E), histidine (H), lysine (K), and arginine (R), and positive-negative ratios of amino acids in the ABCB1 and ABCC5 TMDs are shown in Table ... chamber that transports organic anions Substrates for these transporters bind to a binding site accessible to the intracellular side of the transporters During the translocation process the binding...
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Nghiên cứu về phát triển ngôn ngữ cho học sinh trường Tiểu học Đoàn Xá thông qua điệu ca, bài hát và trò chơi = A study on using chants, songs and games to DEVELOP LANGUAGE IN TEACHING ENGLISH TO  STUDENTS AT DOAN XA PRIMARY SCHOOL

Nghiên cứu về phát triển ngôn ngữ cho học sinh trường Tiểu học Đoàn Xá thông qua điệu ca, bài hát và trò chơi = A study on using chants, songs and games to DEVELOP LANGUAGE IN TEACHING ENGLISH TO STUDENTS AT DOAN XA PRIMARY SCHOOL

Giáo dục học

... exercises - Working together in pairs or groups, comparing and discussing their answers, or reading and reacting to one another’s written work and suggesting improvements - Working together in discussions ... personally involved in a story as they identify with the characters and try to interpret the narrative and illustrations Stories also link fantasy and imagination with the child’s real world They provide ... table The median is fairly corresponding to the mean of the two classes The final thing on the above table is the standard deviation 1.19 is the standard deviation in class 3A and 1.12 is that in...
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Teaching academic content and literacy to english learners in elementary and middle school

Teaching academic content and literacy to english learners in elementary and middle school

Anh ngữ phổ thông

... working toward something important Then anchor this word in the zoo text material by explaining how the zoo administrators were working toward something important, using the phrase like the zoo administrators ... the target word investigation, one student sketched a detective investigating a crime and wrote the following sentence: The detective led an investigation to find the stolen paintings After the ... and celebration, imagine and imagination) and then asking them what the words have in common She explained that the suffix -tion can change words from an action into a thing or idea To deepen...
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Báo cáo khoa học: Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model doc

Báo cáo khoa học: Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model doc

Báo cáo khoa học

... preferentially bind to guanines in methylated CpG sites, and UV irradiation often modifies methylated cytosines [31– 33] Thus, in cells exposed to such factors, mutations within methylated CpG sites ... posttranslational modifications (e.g phosphorylation and acetylation) that inhibit the interaction of p53 and MDM2 and can regulate its activity and location in the cell [13] Once p53 is stabilized and ... experimentally-induced A fi T mutations (at codon 139) matches the TP53 mutation reported in a urothelial carcinoma of an AAN patient in the UK [88] In urothelial tumours of BEN patients from Croatia (n...
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