6 sofa and mod scores and its prognostic value in septic patients
Báo cáo y học: "Endothelial Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients" potx
... filtration rate; ICU: intensive care unit; IGF-1: insulin-like growth factor 1; IL -6: interleukin 6; IL-10: interleukin 10; INR: international normalized ratio; P: P -value; PCHE: pseudocholinesterase; ... survival/overall survival (black line, AUC 0 .66 8/0 .68 6) with established clinical ICU scores as APACHE II (grey line, AUC 0.541/0.598) and SAPS (dotted black line, AUC 0.807/0.7 36) patients or the subgroups ... markers of inflammation/infection (CRP, PCT), hepatic (albumin, international normalized ratio (INR)) and renal (creatinine) function at admission, suPAR remained an independent significant prognostic...
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Báo cáo khoa học: " Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: a population-based stud" pps
... overload in 178 (74%), metabolic acidosis in 87 ( 36% ), uremia in 68 (28%), hyperkalemia in 59 (25%), and toxins in (2%) The modality of renal replacement in the ICU was exclusively CRRT in 147, ... glomerular, and (4%) interstitial etiologies Toxic exposures included parenteral radiocontrast media in 107 (45%), aminoglycosides in 47 (20%) and amphotericin B in 10 (4%) The indications for institution ... difference in mortality risk between sexes for age
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Báo cáo hóa học: " Colistin: recent data on pharmacodynamics properties and clinical efficacy in critically ill patients" pot
... necessary In a patient undergoing continuous venovenous hemodiafiltration, conversion of CMS to colistin was rapid, and the terminal half-lives of CMS and colistin were 6. 8 and 7.5 h, respectively [ 16] ... resistance in MDR K pneumoniae strains Colistin’s pharmacokinetic properties The main pharmacokinetics (PK) of colistin are presented in Table Few studies have addressed the PKs of CMS and colistin in ... daily dosing of colistin on antibacterial effect and emergence of resistance: studies with Pseudomonas aeruginosa in an in vitro pharmacodynamic model J Antimicrob Chemother 2008, 61 :63 6 -64 2 Bergen...
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Báo cáo khoa học: "Discrepancies between clinical and postmortem diagnoses in critically ill patients: an observational study" pptx
... (urinary tract) In contrast, only 17 (45%) cases showed complete agreement between clinical diagnoses and postmortem findings The remaining six patients ( 16% ) had only minor additional findings ... unexpected findings, leading to a falsely high incidence of missed diagnoses However, there is evidence that clinical diagnostic certainty does not predict postmortem findings, indicating that the incidence ... survival Class III and IV discrepancies refer to minor missed diagnoses, either unrelated incidental findings or pre-existing Trends in intensive care unit and hospital postmortem examination rates...
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Báo cáo khoa học: "Outcome and prognostic factors in critically ill patients with systemic lupus erythematosus: a retrospective study" pdf
... Yes 6. 97 (0.98–49 .68 ) No 0.05 Conclusion Intracranial haemorrhage in the ICU Yes 18 .68 (1.13–307. 06) No 0.04 Concurrent septic shock Yes 77. 06 (6. 85– 866 .90) No
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Báo cáo khoa học: "Anemia, transfusion, and phlebotomy practices in critically ill patients with prolonged ICU length of stay: a cohort study" doc
... iron and erythropoietin, and weekly hemoglobin indices to day 21 Patients admitted with pre-existing diagnoses of hypothyroidism (13 patients) or vitamin B12 deficiency (four patients) were continued ... transfuseda (n = 71) P value 62 .9 ± 15.8 0. 56 Male (n [%]) 98 (63 %) 35 (59%) 50 (70%) 0.19 BMIb (kg/m2) 26. 6 ± 7.3 26. 6 ± 7.1 26. 5 ± 7.8 0.95 Surgical (%) 64 (41%) 19 (32%) 33 ( 46% ) 0.10 APACHE II ... Hemoglobin (g/dl) aExcludes 25 patients with active bleeding bBMI unavailable for three bleeding patients and 12 nonbleeding patients (five nontransfused patients and seven transfused patients) ...
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Báo cáo y học: "Longitudinal increases in mitochondrial DNA levels in blood cells are associated with survival in critically ill patients" pdf
... in a porcine model of endotoxin-induced acute lung injury Shock 19 96, 6: S23-S 26 34 Heyland DK, Dhaliwal R, Suchner U, Berger MM: Antioxidant nutrients: a systematic review of trace elements and ... 0.8 0 .6 0 .6 0.4 0.4 0.2 0.2 0.0 mtDNA/nDNA ratio 1 .6 0.0 baseline ± days baseline ± days Change in mitochondrial DNA (mtDNA)/nuclear DNA (nDNA) ratio between baseline and day (± 1) in the intensive ... survivors and non-survivors after adjusting for platelet counts, white blood cell count, and antioxidant dosing group In addition, a linear mixed model with random patient intercepts and slopes...
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Báo cáo y học: "The relationship between gastric emptying, plasma cholecystokinin, and peptide YY in critically ill patients" ppt
... Twentyfive patients (64 %) were sedated with morphine and midazolam, and 14 patients ( 36% ) with propofol Nineteen patients (48%) required inotropic support with either adrenaline or noradrenalin Acid ... baseline to t = 60 minutes and t = 120 minutes), and demographic factors (age, body mass index [BMI], Acute Physiology and Chronic Health Evaluation [APACHE] II score [41], and serum creatinine) ... therapy within 24 hours prior to the study; and a history of diabetes mellitus All patients were receiving an insulin infusion according to a standard protocol, which was designed to maintain the...
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Báo cáo y học: "Circulating angiopoietin-1 and angiopoietin-2 in critically ill patients: development and clinical application of two new immunoassays" pot
... 20 06, 34: 164 7- 165 3 24 Harbarth S, Holeckova K, Froidevaux C, Pittet D, Ricou B, Grau GE, Vadas L, Pugin J: Diagnostic value of procalcitonin, interleukin -6, and interleukin-8 in critically ill patients ... applicability in the clinical routine • In 94 ICU patients, the Ang-1 and Ang-2 concentrations correlated well with SOFA scores and could be reliably assessed during antibiotic treatment and EDD in the ... value of circulating Ang-1 and Ang-2 in this cohort of critically ill patients In an ongoing prospective trial we shall try to delineate the prognostic value of Ang-1 and Ang-2 in combination with...
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Báo cáo y học: "Hyperglycemia and acquired weakness in critically ill patients: potential mechanisms" pps
... damage and apoptosis in neurons FASEB J 2005, 19 :63 8 -64 0 Chonkar A, Hopkin R, Adeghate E, Singh J: Contraction and cation contents of skeletal soleus and EDL muscles in agematched control and diabetic ... Verwaest C, Bruyninckx F, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouillon R: Intensive insulin therapy in the critically ill patients N Engl J Med 2001, 345:1359-1 367 Van den Berghe ... in patients treated with IIT [12] These data raise several interesting questions Does acute hyperglycemia alter neurons and skeletal muscle in such a way as to produce sustained weakness in patients...
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Báo cáo y học: "Serum neutrophil gelatinase-associated lipocalin at inception of renal replacement therapy predicts survival in critically ill patients with acute kidney injury" potx
... Outcome Trial (HANDOUT), a single-center randomized controlled trial comparing standard and intensified extended dialysis therapy in patients with AKI at seven intensive care units (ICUs) of our ... Essentially, the same results were obtained in an adjusted model incorporating treatment intensity of RRT (standard vs intensified extended dialysis in the original HANDOUT trial) When visualized by ... neutrophil lipocalin (HNL) as a diagnostic tool in children with acute infections: a study of the kinetics Acta Paediatr 2005, 94 :66 1 -66 6 36 Dent CL, Ma Q, Dastrala S, Bennett M, Mitsnefes MM, Barasch...
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Báo cáo y học: "Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi-centre study" pot
... (1 164 ) 5,515 55 .6% (3, 066 ) < 0.0001 Surgical patients 1, 565 28.4% (444) 5,590 48.7% (2,722) < 0.0001 Cardiac and vascular 1, 565 26% (407) 5,590 21 .6% (1,207) 0.0003 Thoracic and respiratory 1, 565 ... medicine course Med Intensiva 2009, 33: 166 -170 Myburgh JA, Higgins A, Jovanovska A, Lipman J, Ramakrishnan N, Santamaria J: A comparison of epinephrine and norepinephrine in critically ill patients ... critically ill patients at higher risk of death Implications for clinicians These findings expand our understanding of lactate as a clinical biomarker in the ICU Relatively small changes in lactate...
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Báo cáo y học: "Early intra-intensive care unit psychological intervention promotes recovery from post traumatic stress disorders, anxiety and depression symptoms in critically ill patients" docx
... ± 1.5 0.4105 Chest 2 .6 ± 1.1 2.5 ± 1 .6 0.7911 Abdominal Extremity 1.7 ± 1.2 2.2 ± 1.4 1.7 ± 1.8 2.3 ± 1 .6 0 .60 86 0.2143 External 0.7 ± 1.2 ± 1.3 0.1 066 69 .9% (95) 76. 7% ( 56) 0.1004 AIS score (mean ... (starting during the phase when the patient is still unconscious) by promoting family-centred decision-making and supporting next of kin to choose appropriate interactions during their bedside visits ... directly by clinical psychologists and a trained and supervised staff of intensivists and nurses, whose purpose is to provide emotional support and coping strategies to conscious patients with...
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Báo cáo y học: "Sedation and renal impairment in critically ill patients: a post hoc analysis of a randomized trial" doc
... for >6 h RIFLE criteria Injury is defined as: increase in serum creatinine to >200 to 300% of baseline or urine output 12 h RIFLE criteria Failure is defined as: increase in serum ... Kidney Injury Network (AKIN) [8] The RIFLE classification was defined as follows: RIFLE criteria Risk is defined as: increase in serum creatinine of ≥ 26. 4 μmol/l (150 to 200% of baseline) or urine ... of 103 patients were included in the analysis (Figure 1) Baseline data are shown in Table Patients are comparable with respect to age, weight, APACHE II, SOFA score, S-creatinine and urine output...
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Báo cáo y học: "Serum resistin levels in critically ill patients are associated with inflammation, organ dysfunction and metabolism and may predict survival of non-septic patients" potx
... human glucose metabolism and insulin resistin, unlike the findings in murine models, is still unclear In our cohort as well as in a prior study of septic patients [9], resistin did not correlate ... hyperglycemia, and insulin resistance in several studies [14, 26, 27] In contrast, other studies could not verify these findings in insulin-resistant patients or those with type diabetes [28,29]; resistin ... resistin expression by insulin and rosiglitazone and the effects of recombinant resistin on lipid and glucose metabolism in human differentiated adipocytes J Clin Endocrinol Metab 2003, 88 :60 98 -61 06...
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Báo cáo hóa học: " Renal and neurological side effects of colistin in critically ill patients" docx
... calcineurin inhibitor, hyperbilirubinemia, and hypoalbuminemia The incidence of kidney injury increased with an increase in the number of risk factors Hypoalbuminemia also was identified as an independent ... a doubling of serum creatinine in of 12 patients (41 .6% ) treated with intravenous CMS for at least days [18] Once again, these patients had severe underlying diseases and comorbidities and all ... pathogen) and pneumonia (compared with bacteremia and abdominal infection), whereas age and proportional increase in creatinine independently predicted unfavorable infection outcome Lower mean colistin...
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Báo cáo y học: "Systematic review: The relation between nutrition and nosocomial pneumonia: randomized trials in critically ill patients" doc
... difference in pneumonia between trauma patients fed Immun-Aid (containing glutamine, arginine, omega-3-polyunsaturated fatty acids, nucleotides, and branched chain aminoacids) vs Vivonex (standard ... feeding formulae and their relation to lung infection The first compared modular tube feeds (a high protein, low fat, linoleic acid-restricted formulation enhanced with arginine, cysteine, vitamin ... those 19 patients receiving prepyloric gastric feeds and no cases were observed in the 19 patients receiving post-pyloric feeds through a jejunal tube To avoid continuous alkalinization and intragastric...
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Báo cáo y học: "Prevention and diagnosis of venous thromboembolism in critically ill patients: a Canadian survey" ppt
... particularly in pulmonary medicine [31] and VTE [32], could better inform clinical decisions and minimize the dissemination of nondiscriminating and unnecessary tests Pressing investigations in this ... heparin in this population This is not the case for trauma patients; in one landmark trial, Geerts et al identified DVT in 31% of patients randomized to receive enoxaparin compared with 44% in patients ... priorities in critical care BMJ 2000, 320:9 76- 980 Carrington M, Lachs MS, Feinstein AR: Use of methodologic standards in diagnostic test research JAMA 1995, 274 :64 565 1 Heffner JE, Feinstein D, Barbieri...
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Báo cáo khoa học: " Accidental catheter removal in critically ill patients: a prospective and observational study" doc
... 491 982 29 06 2. 96 ± 1.84 0 TD 70 98 529 7.55 ± 8.97 3. 06 0. 56 AD 65 112 7 46 11.47 ± 11.02 4. 46 0 .67 IBD 68 79 60 6 8.91 ± 11 .65 5. 06 0 .66 AD, abdominal drain; CSD, cardiac surgical drain; ETT, endotracheal ... drainage tube following cardiac surgery in 491 (49 .69 %), thoracic drain in 70 (7.08%), abdominal drain in 65 (6. 57%) and intraventricular brain drainage tube in 68 (6. 89%) Discussion Before we undertook ... ACR Incidence density of ACR1 Peripheral 257 331 2 169 8.43 ± 9.21 0.90 0.13 Jugular 61 8 69 8 4131 6. 68 ± 6. 91 11 1.57 0. 26 Subclavian 321 432 3 862 12.03 ± 12.83 1 .62 0.18 Femoral 111 147 12 16 10.95...
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