4—retrieve objects of function type in the oradev schema
Báo cáo khoa học: Essential roles of lipoyl domains in the activated function and control of pyruvate dehydrogenase kinases and phosphatase isoform 1 pot
... domain E3BP domains: L3, N-terminal lipoyl domain; B, E3 binding domain; I, inner domain which associates with the inner domain of E2 Dotted connections indicate binding interactions to the catalytic ... association involves the ATP-using C-terminal domains interacting near the base of that side of the wedge outside; the N-terminal domains form the outside of the wedges The wedge pockets have ... by an insulinactivated pathway [2] Impaired functioning in insulininduced down-regulation of PDK4 (due to lack of insulin or insensitivity to insulin) deleteriously leads to overexpression of PDK4...
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Báo cáo Y học: The expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis doc
... protein and the mRNA were faint Effects of inhibitors of cGCS and GR on primary cultured testicular cells To investigate the contribution of de novo synthesis and the recycling of GSH to the intracellular ... protein metabolism in these cells Histone is rich in the basic amino acids, lysine and arginine, but contains no cysteine Protamine, which is replaced for hitstone via transit proteins during ... level of GR in the epithelia of the epididymis (Fig 1) As the epididymis is rich in sulfoxidase, the oxidation of sulfhydryls in the sperm head and tail would be mediated by this enzyme in a specific...
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Báo cáo khóa học: The structure–function relationship in the clostripain family of peptidases potx
... mechanisms [42,44] The study of the effect of pH on enzyme inactivation allows the calculation of the pKa of the His176 side chain involved in the inactivation reaction The rate of inactivation exhibited ... nitrogen atoms of the backbone of the residue preceding the catalytic Cys The conservation of this interaction is suggestive of its Fig The nal model of the clostripain catalytic domain The ribbon ... for details) in smaller face The model is of the cleaved clostripain lacking the internal nonapeptide The nal residue of the resultant a-chain, Arg181, and the rst residue of the b-chain, Ala191,...
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Báo cáo hóa học: " Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients" docx
... size In order to gain better insights about the role of miRNAs in DM1, Page of we have also analyzed the muscular expression of the miR-103 and miR-107 CTG-repeat binding miRNAs A combination of ... to the chronic pathology observed in the mdx diaphragm by repressing expression of genes that otherwise would serve a compensatory function, limiting the severity of the disease, as in the hindlimb ... miR-107 to the 3'UTR of the DMPK expanded mRNAs could therefore affects the stoichiometry of free to bound CTG-repeat binding miRNAs, or otherwise disrupt the CTG-repeat binding miRNA function in DM1...
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Báo cáo sinh học: " Improvement of cardiac contractile function by peptide-based inhibition of NF-B in the utrophin/dystrophin-deficient murine model of muscular dystrophy" potx
... blocks and used for the following staining procedures Page of 10 For viewing of gross histology, sections were fixed in 100% ethanol and then stained with hematoxylin and eosin using standard procedures ... efficacy of the NBD peptide in cardiac muscles of dko treated mice Both NF-B DNA binding activity, as well as nuclear levels of the p65 subunit of NF-B were elevated in the dko heart In general, ... contractile dysfunction in dko mice occurs through the inhibition of the NF-B signaling pathway Lastly, we investigated whether NBD treatment of dko mice resulted in an improvement in cardiac histopathological...
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Báo cáo hóa học: " Contribution of cysteine residues in the extracellular domain of the F protein of human respiratory syncytial virus to its function" docx
... glycosylation These findings are intriguing given that these three cysteine residues are absolutely conserved not only in the F proteins of other Pneumovirinae, but also in the F proteins of the Paramyxovirinae ... of the individual cysteine residues in the extracellular domain in protein expression and cell fusion of the HRSV F protein and represents the first analysis of the contribution of the cysteine ... To determine the contribution of the individual cysteine residues in the extracellular domain (ECD) to its functions, a panel of mutations in which each cysteine residue in the ECD of the HRSV...
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báo cáo hóa học:" Improvement of cardiac contractile function by peptide-based inhibition of NF-B in the utrophin/dystrophin-deficient murine model of muscular dystrophy" doc
... blocks and used for the following staining procedures Page of 10 For viewing of gross histology, sections were fixed in 100% ethanol and then stained with hematoxylin and eosin using standard procedures ... efficacy of the NBD peptide in cardiac muscles of dko treated mice Both NF-B DNA binding activity, as well as nuclear levels of the p65 subunit of NF-B were elevated in the dko heart In general, ... contractile dysfunction in dko mice occurs through the inhibition of the NF-B signaling pathway Lastly, we investigated whether NBD treatment of dko mice resulted in an improvement in cardiac histopathological...
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everyone is a customer a proven method for measuring the value of every relationship in the era of collaborati phần 4 ppt
... encourage win-win thinking, as the required levels of trust and cooperation will not grow if one or both parties seeks to take advantage of the other That kind of win-lose attitude inevitably ... homework, learning about the quantities of perishables moving about the world and the amount of business they could potentially represent to FedEx She then approached the company with the following value ... include both free agents and major consulting firms, so Chris and Joe understand they can’t win customers by offering the lowest price, nor can they afford the kind of marketing and advertising...
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Primary Care of Musculoskeletal Problems in the Outpatient Setting - part 4 pot
... of the floor of the snuffbox All these landmarks are noted in Figure 7.8 The examination in SLLD is positive for discomfort in the snuffbox and pain in the midportion of the wrist Follow the ... over the median nerve at the wrist (Figure 7.5) A positive test (Tinel’s sign) is the production of tingling on the palmer surface of the thumb, index finger, and a portion of the middle finger ... finger Test the strength of the thenar muscles by assessing the ability of the thumb to move toward the little finger against resistance (Figure 7.6) Placing the wrists together in maximum flexion...
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Báo cáo y học: " Loss of function mutation in toll-like receptor-4 does not offer protection against obesity and insulin resistance induced by a diet high in trans fat in miceg" pdf
... the TLR4 Further, we hypothesize that a loss of function mutation in TLR4 may protect against high TF diet-induced inflammation and insulin resistance in mice Therefore, the objective of this current ... hyperinsulinemia, and inflammation in response to diet high in saturated fat [23] Although, we did not observe the blunting of TF dietinduced weight gain, hyperinsulinemina, and hyperglycemia in ... exacerbated in the presence of loss of function mutation in TLR4 Furthermore, our results indicate that TLR4 independent pathways may be involved in TF-diet-induced obesity, hyperglycemia, hyperinsulinemia,...
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Báo cáo y học: "Loss of function mutation in toll-like receptor-4 does not offer protection against obesity and insulin resistance induced by a diet high in trans fat in mice" docx
... the TLR4 Further, we hypothesize that a loss of function mutation in TLR4 may protect against high TF diet-induced inflammation and insulin resistance in mice Therefore, the objective of this current ... hyperinsulinemia, and inflammation in response to diet high in saturated fat [23] Although, we did not observe the blunting of TF dietinduced weight gain, hyperinsulinemina, and hyperglycemia in ... exacerbated in the presence of loss of function mutation in TLR4 Furthermore, our results indicate that TLR4 independent pathways may be involved in TF-diet-induced obesity, hyperglycemia, hyperinsulinemia,...
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Care of Musculoskeletal Problems in the Outpatient Setting - part 4 docx
... of the floor of the snuffbox All these landmarks are noted in Figure 7.8 The examination in SLLD is positive for discomfort in the snuffbox and pain in the midportion of the wrist Follow the ... over the median nerve at the wrist (Figure 7.5) A positive test (Tinel’s sign) is the production of tingling on the palmer surface of the thumb, index finger, and a portion of the middle finger ... finger Test the strength of the thenar muscles by assessing the ability of the thumb to move toward the little finger against resistance (Figure 7.6) Placing the wrists together in maximum flexion...
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Treatment of Osteoarthritic Change in the Hip - part 4 docx
... According to the preoperative planning, ARO with 20° varus position was expected to result in more than 34% of the ratio of the intact articular in both the joints The osteotomy was carried out in ... high level of activities in 2, degenerative change in 2, and challenging procedure in because of the young age of the patient Discussion Several kinds of procedures for joint preservation of femoral ... determined according to the radiographic classification of the Japanese Investigation Committee, was type B for hips, type C-1 for 20, and type C-2 for 32 hips The clinical results of steroid-induced...
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Báo cáo y học: "Enhanced effector function of cytotoxic cells in the induced sputum of COPD patients" doc
... changes in the airway The first step of assessing the potential importance of these cells in the inflammatory process would be to assess their numbers and function within the airways Therefore, in ... this study we have extended the findings of our previous study to investigate, within induced sputum, the number and cytotoxic function of the three main classes of human killer cells; CD8 + ... although the measurement may have included two other types of killer cells (namely NK and NKT-like cells) as these can also express CD8 on the cell surface Information on the functional phenotypes of...
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Báo cáo y học: " Effects of cigarette smoke on endothelial function of pulmonary arteries in the guinea pig" ppsx
... the effect of contraction to NE by including it in the model The significance of the independent factors was assessed by the common ANOVA F-test using the type- 3 sum of squares The adequacy of ... that in non-smokers and COPD patients, thereby indicating that endothelial dysfunction is present at the origin of the disease [2] The impairment of endothelial function results from changes in the ... funding support and contributed in the analysis of the data JAB conceived the study, raised funding support, participated in the design and implementation of the study, and in the revision of the...
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Identification of factors involved in the maintenance of embryonic stem cell self renewal and pluripotency 4
... the C-terminus of Lefty2 was chosen instead of the N-terminus because tagging at N-terminus may result in the V5 tag being cleaved off during LEFTY2 processing and secretion The insert was amplified ... for the entire duration of the experiment The E14 cells were fed daily with medium containing fresh Activin A 4.14.2 Inhibition of Nodal/Activin signaling To abolish/diminish Nodal/Activin signaling, ... overexpression The expression of the Nodal transgene was suppressed in the presence of 1µg/ml doxycyclin (Clontech,UK.) Hence to activate Nodal induction, the drug was removed from the cells by changing the...
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Seafood Supply Chain Quality Management: The Shrimp Supply Chain Quality Improvement Perspective of Seafood Companies in the Mekong Delta, Vietnam
... of Vietnam and the South of Vietnam The structure of Vietnam’s SFC organization The supply chain quality management of interviewed SFCs The fish chain in the Netherlands The shrimp chain in the ... (CDS), the Faculty of Economics of the University of Groningen in the Netherlands, and the School of Economics and Business Administration (SEBA) of Cantho University in Vietnam Numerous institutions, ... crucial Among the chain actors, the role of the SFC is vital – not only in ensuring the quality of the final product, but also in SFC’s material suppliers In order to control the quality of the supplier’s...
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LINH DAM NEW TOWN - SOLUTION FOR THE HIGH-DENSITY DEVELOPMENT OF NEW SETTLEMENTS IN THE SOUTH-WEST OF HANOI
... the central area for the purpose of resettlement Generally, getting along with the rapid expansion, the east bank of the Red River exhibited the beginnings of urbanization The south-west of the ... components: Bac Linh Dam (North of Linh Dam), Linh Dam peninsula in the middle and Linh Dam expansion (South of Linh Dam) The success of the project has set the stage for a series of New Towns that ... tropical climate Among these, the outstanding point is the area of highstorey apartments and office buildings in the center of Linh Dam peninsula, surrounding by low-storey buildings, parks, open...
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LINH DAM NEW TOWN - SOLUTION FOR THE HIGH-DENSITY DEVELOPMENT OF NEW SETTLEMENTS IN THE SOUTH-WEST OF HANOI
... nặng nhọc với mức thu nhập thấp, kéo theo điều kiện sống mức tối thiểu, tạm bợ khu nhà trọ rẻ tiền với điều kiện sinh hoạt an ninh không đảm bảo Đời sống tinh thần lao động hạn chế Họ thấy cô ... làm việc chợ lao động thuê trọ theo ngày (đêm), lại thuê nhà theo tháng Có khoảng 22,86% nữ lao động tự phải sống nơi có điều kiện sinh hoạt không đảm bảo, vệ sinh; 40,95% không sử dụng nước ... vật chất, tinh thần lao động nghèo nàn Họ thường tiêu tiết kiệm cho khoản chi phí sinh hoạt thiết yếu Có 22,86% nữ lao động tự phải sống nơi có điều kiện sinh hoạt thiếu thốn, vệ sinh Họ thường...
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Genotoxicity of 255 chemicals in the Salmonella microsome test (Ames test) and 8-hydroxyguanine (8-OH-Gua) assay for the detection of carcinogens
... Identification of C8-modified deoxyinosine and N2- and C8-modified deoxyguanosine as major products of the in vivo reaction of N-hydroxy-6-aminochrysene with DNA and the formation of the adducts in isolated ... recommend the Ames test using these sensitive strains (especially YG1041 and/or YG1042) in combination with the standard tester strains (TA98 and TA100 series), in order to detect the mutagenicity of ... ogttST::Cmr) strain (deficient in O6-methylguanine DNA methyltransferase) sensitive to alkylating chemicals These strains were kindly supplied by Dr T Nohmi of the National Institute of Health Sciences...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25