... supported by research grants from National Science Council(NSC 97 -31 11-B-075-001-MY3, NSC99-2811-B-016-007-MY3, 98- 232 0-B-075-003MY3), Taipei Veterans General Hospital (V97B1-006, E1-008, F-001), ... and nitrosoureas for the treatment of malignant glioma after surgery N Engl J Med 1980, 30 3( 23) : 132 3- 132 9 Stupp R, Dietrich PY, Ostermann Kraljevic S, Pica A, Maillard I, Maeder P, Meuli R, Janzer ... of DNA minor groovetargeted aniline mustard analogues of pibenzimol (Hoechst 33 258) J Med Chem 1994, 37 (25): 433 8- 434 5 Gourdie TA, Valu KK, Gravatt GL, Boritzki TJ, Baguley BC, Wakelin LP, Wilson...
... migration [%] 100 80 60 40 20 U251MG U343MG B DMSO μM BA 10μM BA U251MG U343MG Figure Effects of BA on cell migration of glioma cells Migration rates of U251MG and U343MG cells treated with BA analyzed ... http://www.ro-journal.com/content/6/1/111 Page of clonogenic survival [%] 120 100 U251MG 80 U343MG 60 40 20 0 10 20 30 betulinic acid [μM] Figure Cytotoxicity in U251MG and U343MG cell lines after treatment with BA Both glioma cell ... (p = 0. 03) in U251MG cells and 87% (p = 0.15) or 82% (p = 0.07) in U343MG cells, respectively Under hypoxic conditions, an increased reduction in survival to 30 % (p = 0.01) or 9% (p = 0. 03) and...
... regulates IFN-γ – induced JAK/STAT and p38 phosphorylation differently in C6 glioma cells and RAW264.7 macrophages ························· 72 iii 3.3 Involvement of p38 and JAK/STAT in IFN-γ – induced ... astrocytoma cell line U3 73- MG, and mouse macrophage cell line Raw264.7 were purchased from the American Type Culture Collection (Manassas, VA, USA) C6 cells, SH-SY5Y cells, and U3 73- MG were cultured ... ································································ 36 12 Cell transfection and RNA interference ·························································· 38 13 Statistical analysis ··························································································...
... inactivated split-virus Page of 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 influenza A (H5N1) vaccine in infants and children Vaccine 2008, 26: 638 3- 639 1 Treanor JJ, Campbell JD, Zangwill ... National 9 73 Project (2010CB 530 301), European Union Project (SSPE-CT-2006-44405), National Natural Science Foundation of China (30 9726 23) , National Key Technology R&D Program of China (2006BAD06A 03) , ... M1 DNA NP + M1 DNAs Pre-exposed to H1N1 Not done 22 .3 ± 1.15a, Unimmunized control 17.0 ± 1.0 b b Not done 12.7 ± 1.15a, 13. 3 ± 0.57a, b b 9 .33 ± 0.57 § Mice were grouped and treated as described...
... cerevisiae Proc Natl Acad Sci USA 2002, 99:15 530 -15 535 Briza P, Bogengruber E, Thur A, Rutzler M, Munsterkotter M, Dawes 25 26 27 28 29 30 31 32 33 34 35 36 Genome Biology 2006, 7:R20 information ... Analysis of the kar3 meiotic arrest in Saccharomyces cerevisiae Cell Cycle 2004, 3: 3 63- 371 Cohen-Fix O: Meiosis: polo, FEAR and the art of dividing reductionally Curr Biol 20 03, 13: R6 03- R605 Lee BH, ... GEO [59] and are accessible through GEO Series accession numbers: GSE3814, GSE3815, GSE3816, GSE3817, GSE3818, GSE3819 and GSE3820 [57,58] (see also Additional data file 4) Calculating the correlation...
... activation [33 ] In our study, we evaluated the effect of Osthole on the PI3K/Akt Xu et al Journal of Experimental & Clinical Cancer Research 2011, 30 :33 http://www.jeccr.com/content /30 /1 /33 pathways ... of solid tumours Nature 2005, 435 :677-81 Xu et al Journal of Experimental & Clinical Cancer Research 2011, 30 :33 http://www.jeccr.com/content /30 /1 /33 Page of 30 Thees S, Hubbard GB, Winckler ... buffer(20 mM Xu et al Journal of Experimental & Clinical Cancer Research 2011, 30 :33 http://www.jeccr.com/content /30 /1 /33 Page of HEPES, pH 7.9, 20% glycerol, 200 mM KCl, 0.5 mM EDTA, 0.5% NP40,...
... on the protein expression of p21, p 53 and 14 -3- 3σ Actin was used as the internal control Control 0.25% 0.5% 1% 2.5% 5% 10% MW kDa p 53 53 Actin 43 14 -3- 3σ 30 p21 21 ... 2.7 2.9 4.0 4.7 5.0 5.0 p 53 Disscussion 0.8 2.5 3. 0 3. 4 5.0 14 .3 p21 Cell cycle checkpoints are important control 1.0 1.5 1.2 2.0 2.4 3.3 14 -3- 3 mechanisms that ensure the proper execution of ... and 14 -3- 3 sigma negatively regulates cell cycle progression JBC 2000; 275: 231 06- 231 12 24 Urano T, Saito T, Tsukui T, Fujita M, Hosoi T, Muramatsu M, Ouchi Y, Inoue S Efp targets 14 -3- 3 sigma...
... mitochondrial cell death protein BNIP3 Oncogene 2005, 24:980–91 http://www.translational-medicine.com/content/7/1/ 13 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 Fulda S, Jeremias ... apoptosis signaling by retinoid CD 437 J Biol Chem 20 03, 278 :33 422 35 Kim HJ and Lotan R: Identification of protein modulation by the synthetic retinoid CD 437 in lung carcinoma cells using high ... for two minutes, 30 cycles including 95°C for 30 seconds, 57°C for 45 seconds, 72°C for 30 seconds For EGFR amplification: 95°C for two minutes, 32 cycles including 95°C for 30 seconds, 55°C...