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3 phát huy sức mạnh đại đoàn kết toàn dân tộc kết hợp sức mạnh dân tộc với sức mạnh thời đại trong bối cảnh hiện nay

Báo cáo khoa học:

Báo cáo khoa học: " Enhancement of radiosensitivity in human glioblastoma cells by the DNA N-mustard alkylating agent BO-1051 through augmented and sustained DNA damage response" potx

Báo cáo khoa học

... supported by research grants from National Science Council(NSC 97 -31 11-B-075-001-MY3, NSC99-2811-B-016-007-MY3, 98- 232 0-B-075-003MY3), Taipei Veterans General Hospital (V97B1-006, E1-008, F-001), ... and nitrosoureas for the treatment of malignant glioma after surgery N Engl J Med 1980, 30 3( 23) : 132 3- 132 9 Stupp R, Dietrich PY, Ostermann Kraljevic S, Pica A, Maillard I, Maeder P, Meuli R, Janzer ... of DNA minor groovetargeted aniline mustard analogues of pibenzimol (Hoechst 33 258) J Med Chem 1994, 37 (25): 433 8- 434 5 Gourdie TA, Valu KK, Gravatt GL, Boritzki TJ, Baguley BC, Wakelin LP, Wilson...
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báo cáo hóa học:

báo cáo hóa học:" Effects of alpha-calcitonin gene-related peptide on osteoprotegerin and receptor activator of nuclear factor-B ligand expression in MG-63 osteoblastlike cells exposed to polyethylene particles" doc

Hóa học - Dầu khí

... 0.82 ± 0. 03 0.82 ± 0. 03 0.75 ± 0.04 0. 73 ± 0.02 0.72 ± 0.04 0. 73 ± 0. 03 48 h 0.82 ± 0.04 0.81 ± 0.04 0.82 ± 0.02 0.80 ± 0.04 0.71 ± 0.02 0.71 ± 0.05 0.71 ± 0. 03 0.71 ± 0.04 72 h 0.81 ± 0. 03 0.80 ... Gynecol 2006, 45 :30 7 -31 2 30 Dempsey PW, Doyle SE, He JQ, Cheng G: The signaling adaptors and pathways activated by TNF superfamily Cytokine Growth Factor Rev 20 03, 14:1 93- 209 31 Rakshit DS, Ly ... Orthopaedic Surgery and Research 2010, 5: 83 http://www.josr-online.com/content/5/1/ 83 bone matrix that stimulate osteoblasts to promote or inhibit bone formation [32 ,33 ] This may have an impact on the...
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báo cáo hóa học:

báo cáo hóa học:" Effects of alpha-calcitonin gene-related peptide on osteoprotegerin and receptor activator of nuclear factor-B ligand expression in MG-63 osteoblastlike cells exposed to polyethylene particles" pot

Hóa học - Dầu khí

... 0.82 ± 0. 03 0.82 ± 0. 03 0.75 ± 0.04 0. 73 ± 0.02 0.72 ± 0.04 0. 73 ± 0. 03 48 h 0.82 ± 0.04 0.81 ± 0.04 0.82 ± 0.02 0.80 ± 0.04 0.71 ± 0.02 0.71 ± 0.05 0.71 ± 0. 03 0.71 ± 0.04 72 h 0.81 ± 0. 03 0.80 ... Gynecol 2006, 45 :30 7 -31 2 30 Dempsey PW, Doyle SE, He JQ, Cheng G: The signaling adaptors and pathways activated by TNF superfamily Cytokine Growth Factor Rev 20 03, 14:1 93- 209 31 Rakshit DS, Ly ... Orthopaedic Surgery and Research 2010, 5: 83 http://www.josr-online.com/content/5/1/ 83 bone matrix that stimulate osteoblasts to promote or inhibit bone formation [32 ,33 ] This may have an impact on the...
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Báo cáo khoa học:

Báo cáo khoa học: "Increased betulinic acid induced cytotoxicity and radiosensitivity in glioma cells under hypoxic conditions" pptx

Báo cáo khoa học

... migration [%] 100 80 60 40 20 U251MG U343MG B DMSO μM BA 10μM BA U251MG U343MG Figure Effects of BA on cell migration of glioma cells Migration rates of U251MG and U343MG cells treated with BA analyzed ... http://www.ro-journal.com/content/6/1/111 Page of clonogenic survival [%] 120 100 U251MG 80 U343MG 60 40 20 0 10 20 30 betulinic acid [μM] Figure Cytotoxicity in U251MG and U343MG cell lines after treatment with BA Both glioma cell ... (p = 0. 03) in U251MG cells and 87% (p = 0.15) or 82% (p = 0.07) in U343MG cells, respectively Under hypoxic conditions, an increased reduction in survival to 30 % (p = 0.01) or 9% (p = 0. 03) and...
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báo cáo khoa học:

báo cáo khoa học: "Adenovirus-mediated delivery of bFGF small interfering RNA reduces STAT3 phosphorylation and induces the depolarization of mitochondria and apoptosis in glioma cells U251" pdf

Báo cáo khoa học

... activities of basic fibroblast growth factor: potentiation of low-serum 25 26 27 28 29 30 31 32 33 34 35 36 37 38 growth mediated by natural or chimeric nuclear localization signals Mol Biol Cell ... 2004, 23: 330 8 -33 16 21 Ren W, Duan Y, Yang Y, Ji Y, Chen F: Down-regulation of Stat3 induces apoptosis of human glioma cell: a potential method to treat brain cancer Neurol Res 2008, 30 :297 -30 1 22 ... mouse model Oncogene 2004, 23: 330 8 -33 16 Lee H, Herrmann A, Deng JH: Persistently activated STAT3 maintains constitutive NF-kB activity in tumors Cancer Cell 2009, 15:2 83- 2 93 Brantley EC, Benveniste...
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molecular merchanisms underlying inhibitory effect of fuciodan on cytokine-induced inflammation in glioma cells

molecular merchanisms underlying inhibitory effect of fuciodan on cytokine-induced inflammation in glioma cells

Tiến sĩ

... regulates IFN-γ – induced JAK/STAT and p38 phosphorylation differently in C6 glioma cells and RAW264.7 macrophages ························· 72 iii 3. 3 Involvement of p38 and JAK/STAT in IFN-γ – induced ... astrocytoma cell line U3 73- MG, and mouse macrophage cell line Raw264.7 were purchased from the American Type Culture Collection (Manassas, VA, USA) C6 cells, SH-SY5Y cells, and U3 73- MG were cultured ... ································································ 36 12 Cell transfection and RNA interference ·························································· 38 13 Statistical analysis ··························································································...
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Báo cáo khoa học:

Báo cáo khoa học: "Molecular analysis of hprt mutation in B6C3F1 mice exposed to ozone alone and combined treatment of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate for 32 and 52 weeks" ppsx

Báo cáo khoa học

... with 4(N-methyl-N-nitrosamino)-1- (3- pyridyl)-1-butanone and dibutyl phthalate enhanced ozone-induced genotoxicity in B6C3F1 38 5 mice Mutagenesis 2002, 17, 33 1 -33 6 22 Koren HS, Devlin RB, Graham ... Interact 1981, 34 , 233 - 238 11 Gray TJ, Beamand JA Effect of some phthalate esters and other testicular toxins on primary cultures of testicular cells Food Chem Toxicol 1984, 22, 1 23- 131 12 Harris ... µl of hprt-specific 5' primer (10 mM: 5GGC TTC CTC CTC AGA CCG CT -3) and 3' primer (10 mM: 5-GGC AAC ATC AAC AGG ACT CC -3) , 0 .3 µl of Taq DNA polymerase (5 U/µl) (Takara, Japan), and 22.7 µl of...
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Báo cáo khoa học:

Báo cáo khoa học: " Effect of dihydrotestosterone on mouse embryonic stem cells exposed to H2O2-induced oxidative stress" pdf

Báo cáo khoa học

... 2006, 33 , 211-220 32 Hausburg MA, Dekrey GK, Salmen JJ, Palic MR, Gardiner CS Effects of paraquat on development of preimplantation embryos in vivo and in vitro Reprod Toxicol 2005, 20, 239 -246 33 ... Cells 2004, 6, 38 6 -39 1 17 Cobb MH, Goldsmith EJ How MAP kinases are regulated J Biol Chem 1995, 270, 148 43- 14846 18 Cochrane CG Cellular injury by oxidants Am J Med 1991, 91, 23S -30 S 19 Du J, Daniels ... on cell survival Biochem J 1998, 33 3, 291 -30 0 59 Ward PA, Warren JS, Johnson KJ Oxygen radicals, inflammation, and tissue injury Free Radic Biol Med 1988, 5, 4 03- 408 60 Wolf R, Schönfelder G,...
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Báo cáo khoa học:

Báo cáo khoa học: " Induction of oxidative stress and lipid peroxidation in rats chronically exposed to cypermethrin through dermal application" pps

Báo cáo khoa học

... of the superoxide anion radical in the autoxidation of pyrogallol and a 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 convenient assay for superoxide dismutase Eur J Biochem 1974, 47, 469-474 ... 0.021b 0. 035 ± 0.004a 0.026 ± 0.009c 0. 031 ± 0.006a 0.015 ± 0.012c 0.028 ± 0.004a 0.014 ± 0.010c 3. 35 ± 0 .37 c 8.60 ± 0.55a 2. 93 ± 0.19c 5.50 ± 0.23a 2.71 ± 0.11c 8.75 ± 0.45a 2.59 ± 0.23c a a b ... (nmol.mL ) LPO (nmol of MDA 1 .35 ± 0 .31 a −1 −1 gm Hb h ) 30 days 35 .52 ± 6.18b Control 60 days 14. 53 ± 2.23a 45.25 ± 7.24b Control 19. 23 ± 2.64a 90 days Control 59.51 ± 13. 27b 19.42 ± 2.65a 120 days...
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Enhancement of tolerance development to morphine in rats prenatally exposed to morphine, methadone, and buprenorphine docx

Enhancement of tolerance development to morphine in rats prenatally exposed to morphine, methadone, and buprenorphine docx

Báo cáo khoa học

... 148.1 ± 2.7 132 .3 ± 4.2** 121 .3 ± 3. 3*** 136 .4 ± 3. 7* Body weight of the offspring at birth (g) 6.8 ± 0.1 ± 0.1 6.6 ± 0.1 6.9 ± 0.1 Body weight of the offspring on day (g) 14.7 ± 0 .3 16 .3 ± 0.5* ... Neuropsychopharmacol Biol Psychiatry 20 03, 27 :38 1 -39 3 33 Zagon IS, McLaughlin PJ: Enhanced sensitivity to methadone in adult rats perinatally exposed to methadone Life Sci 1981, 29:1 137 -1142 34 He L, Kim J, Ou C, ... 0 .3 9.8 ± 0 .3 10.2 ± 0 .3 Fatality (%) 0.69 ± 0 .33 0 7.1 ± 2 .38 ** Fatality occurred in the offspring (%) (P2-P10) 0.21 ± 0.14 0.56 ± 0.56 12.14 ± 7.02* Body weight increase in the dams (g) (E3-E20)...
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Báo cáo y học:

Báo cáo y học: " A single dose of DNA vaccine based on conserved H5N1 subtype proteins provides protection against lethal H5N1 challenge in mice pre-exposed to H1N1 influenza virus" ppt

Báo cáo khoa học

... inactivated split-virus Page of 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 influenza A (H5N1) vaccine in infants and children Vaccine 2008, 26: 638 3- 639 1 Treanor JJ, Campbell JD, Zangwill ... National 9 73 Project (2010CB 530 301), European Union Project (SSPE-CT-2006-44405), National Natural Science Foundation of China (30 9726 23) , National Key Technology R&D Program of China (2006BAD06A 03) , ... M1 DNA NP + M1 DNAs Pre-exposed to H1N1 Not done 22 .3 ± 1.15a, Unimmunized control 17.0 ± 1.0 b b Not done 12.7 ± 1.15a, 13. 3 ± 0.57a, b b 9 .33 ± 0.57 § Mice were grouped and treated as described...
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Báo cáo y học:

Báo cáo y học: " Effect of recombinant IL-10 on cultured fetal rat alveolar type II cells exposed to 65%-hyperoxia" pps

Báo cáo khoa học

... http://respiratory-research.com/content/12/1/68 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 basis for the predisposition to chronic lung inflammation in preterm newborns Pediatr Res 1996, 39 :966-975 Kwong KY, ... cells by 66% after 24 h and 36 h of hyperoxia (24 h-untreated = 5.74 ± 1.85 vs 24 h-treated = 2.06 ± 0 .39 ; p < 0.01; 36 huntreated = 9.47 ± 3. 17 vs 36 h-treated = 3. 30 ± 0.56; p < 0.01) (Figure ... 24 h of hyperoxia (untreated = 37 .0 ± 5.99 vs treated = 30 .8 ± 3. 56; p < 0.05) and by 27% after 36 h of hyperoxia (untreated = 54.5 ± 2 .30 vs treated = 39 .8 ± 3. 84; p < 0.01) respectively, when...
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Báo cáo y học:

Báo cáo y học: "Isoniazid prophylaxis differently modulates T-cell responses to RD1-epitopes in contacts recently exposed to Mycobacterium tuberculosis: a pilot study" pdf

Báo cáo khoa học

... Total N.44 35 .5 (17) 49 (60) 21 16 (66) 52 (66) 30 26 (59) 26 (66) (34 ) (33 ) (100) (25) 13 (54) 11 (46) 11 (46) (89) (11) (11) 30 (68) 14 (32 ) 18 (41) (16) (33 ) (50) (20) (80) (29) (37 .) (33 ) (11) ... (100) (100) (100) (100) 14.2 ± 3. 4 31 .4 ± 2.5 16.4 ± 5.1 11.8 ± 3. 8 6.1 ± 17.1 ± 4.5 33 ± 3. 4 12 .3 ± 4.4 8.9 ± 3. 2 2.2 ± 0.5 17.5 ± 4.6 29 .3 ± 4.5 16 .3 ± 6.7 13. 5 ± 6.1 4.6 ± Ns Ns Ns Ns Ns Ns ... (100) (100) (100) (100) 9.9 ± 4 .3 27.4 ± 3. 1 21.1 ± 5.2 16.1 ± 4.5 7.5 ± 3. 3 8.6 ± 4.1 21.4 ± 4.9 19.5 ± 7.2 16 .3 ± 7.2 7.0 ± 4.7 12.1 ± 6.5 23. 5 ± 3. 8 20.2 ± 6.1 7 .3 ± 2.2 5.7 ± Ns Ns Ns Ns Ns...
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Báo cáo y học:

Báo cáo y học: "Modulation of the transcription regulatory program in yeast cells committed to sporulation" ppt

Báo cáo khoa học

... cerevisiae Proc Natl Acad Sci USA 2002, 99:15 530 -15 535 Briza P, Bogengruber E, Thur A, Rutzler M, Munsterkotter M, Dawes 25 26 27 28 29 30 31 32 33 34 35 36 Genome Biology 2006, 7:R20 information ... Analysis of the kar3 meiotic arrest in Saccharomyces cerevisiae Cell Cycle 2004, 3: 3 63- 371 Cohen-Fix O: Meiosis: polo, FEAR and the art of dividing reductionally Curr Biol 20 03, 13: R6 03- R605 Lee BH, ... GEO [59] and are accessible through GEO Series accession numbers: GSE3814, GSE3815, GSE3816, GSE3817, GSE3818, GSE3819 and GSE3820 [57,58] (see also Additional data file 4) Calculating the correlation...
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báo cáo khoa học:

báo cáo khoa học: "Osthole induces G2/M arrest and apoptosis in lung cancer A549 cells by modulating PI3K/Akt pathway" pptx

Báo cáo khoa học

... activation [33 ] In our study, we evaluated the effect of Osthole on the PI3K/Akt Xu et al Journal of Experimental & Clinical Cancer Research 2011, 30 :33 http://www.jeccr.com/content /30 /1 /33 pathways ... of solid tumours Nature 2005, 435 :677-81 Xu et al Journal of Experimental & Clinical Cancer Research 2011, 30 :33 http://www.jeccr.com/content /30 /1 /33 Page of 30 Thees S, Hubbard GB, Winckler ... buffer(20 mM Xu et al Journal of Experimental & Clinical Cancer Research 2011, 30 :33 http://www.jeccr.com/content /30 /1 /33 Page of HEPES, pH 7.9, 20% glycerol, 200 mM KCl, 0.5 mM EDTA, 0.5% NP40,...
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Báo cáo y học:

Báo cáo y học: "Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R." pps

Báo cáo khoa học

... p-Chk1-S345 γ-H2AX-S 139 Vpr β-actin B 10 11 12 13 G1/S G2/M 0h G1 Time S 5h S G1 8h G2 11 h Mock 30 60 90 120 150 30 Vpr HU Cell number Channels (FL2-A) 30 60 90 120 150 30 Channels (FL2-A) 30 60 ... Virology 2001, 287 :35 9 -37 0 34 Goh WC, Manel N, Emerman M: The human immunodeficiency virus Vpr protein binds Cdc25C: implications for G2 arrest Virology 2004, 31 8 :33 7 -34 9 35 Murakami H, Nurse ... 90 120 150 30 60 60 90 120 Channels (FL2-A) 120 150 30 Channels (FL2-A) 60 90 90 120 150 30 60 Channels (FL2-A) Channels (FL2-A) 150 30 60 90 120 150 30 60 Channels (FL2-A) 120 1500 30 Channels...
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Báo cáo y học:

Báo cáo y học: "Cell Cycle Arrest by a Natural Product via G2/M Checkpoint"

Y học thưởng thức

... on the protein expression of p21, p 53 and 14 -3- 3σ Actin was used as the internal control Control 0.25% 0.5% 1% 2.5% 5% 10% MW kDa p 53 53 Actin 43 14 -3- 3σ 30 p21 21 ... 2.7 2.9 4.0 4.7 5.0 5.0 p 53 Disscussion 0.8 2.5 3. 0 3. 4 5.0 14 .3 p21 Cell cycle checkpoints are important control 1.0 1.5 1.2 2.0 2.4 3. 3 14 -3- 3 mechanisms that ensure the proper execution of ... and 14 -3- 3 sigma negatively regulates cell cycle progression JBC 2000; 275: 231 06- 231 12 24 Urano T, Saito T, Tsukui T, Fujita M, Hosoi T, Muramatsu M, Ouchi Y, Inoue S Efp targets 14 -3- 3 sigma...
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Báo cáo Y học: Early growth response-1 gene (Egr-1 ) promoter induction by ionizing radiation in U87 malignant glioma cells in vitro pot

Báo cáo Y học: Early growth response-1 gene (Egr-1 ) promoter induction by ionizing radiation in U87 malignant glioma cells in vitro pot

Báo cáo khoa học

... Cell 76, 1025±1 037 35 Wilhelm, D., van Dam, H., Herr, I., Baumann, B., Herrlich, P & Angel, P (1995) Both ATF-2 and c-Jun are phosphorylated by Ó FEBS 2002 36 37 38 39 40 41 42 43 44 45 stress-activated ... mainly triggered by ultraviolet light (UV-C) [34 36 ], ionizing radiation (reviewed in [37 ]), proin¯ammatory cytokines [30 ,31 ] and DNA damaging agents [37 ], whereas the Raf/ERK pathway is preferentially ... phosphorylated target proteins, i.e ERK1/2 (T202/Y204), SAPK/JNK (T1 83/ Y185), p38MAPK/SAPK2 (T180/Y182), ATF-2 (T71), c-Jun (S 73) and CREB (S 133 ) phosphospeci®c rabbit polyclonal Ig was applied Phosphorylation-state-indepen-...
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báo cáo hóa học:

báo cáo hóa học:" Drugs targeting the mitochondrial pore act as citotoxic and cytostatic agents in temozolomide-resistant glioma cells" pptx

Hóa học - Dầu khí

... mitochondrial cell death protein BNIP3 Oncogene 2005, 24:980–91 http://www.translational-medicine.com/content/7/1/ 13 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 Fulda S, Jeremias ... apoptosis signaling by retinoid CD 437 J Biol Chem 20 03, 278 :33 422 35 Kim HJ and Lotan R: Identification of protein modulation by the synthetic retinoid CD 437 in lung carcinoma cells using high ... for two minutes, 30 cycles including 95°C for 30 seconds, 57°C for 45 seconds, 72°C for 30 seconds For EGFR amplification: 95°C for two minutes, 32 cycles including 95°C for 30 seconds, 55°C...
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Báo cáo sinh học:

Báo cáo sinh học: " G0/G1 arrest and apoptosis induced by SARS-CoV 3b protein in transfected cells" pot

Điện - Điện tử

... 104 104 1 03 10 10 102 100 1000 7. 43% 102 101 100 0. 63% 7-AAD 48h GFP 31 .57% 1 03 2 .39 % 7-AAD 10 0.49% 101 7.94% 100 104 Annexin V PE DNA Content EGFP expression 32 .17% 104 Annexin V PE p3b/EGFP-N1 ... coronavirus Science 20 03, 30 0: 139 9-1404 Oh JC, Jeong DL, Kim IK, Oh SH: Activation of calcium signaling by hepatitis B virus-X protein in liver cells Exp Mol Med 20 03, 35 :30 1 -30 9 Nakamichi K, Matsumoto ... 32 .17% 104 Annexin V PE p3b/EGFP-N1 (-) p3b/EGFP-N1 (+) b 104 GFP 101 101 0 1000 100 1. 73% 102 102 101 0.75% 1 03 0.29% 7-AAD 102 10 0.48% 1 03 7-AAD 32 .40% 1 03 48h 104 104 1.24% 10 104 DNA Content...
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