2 residual tumor resection after chemotherapy for metastatic disease in patients with nonseminomatous germ cell tumors
Báo cáo y học: "Disease-modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: a case control study" doc
... tests were performed using the SPSS 12.0 software package for Windows (SPSS Inc., Chicago, IL, USA) Results Rheumatoid arthritis patients with and without cardiovascular disease The baseline characteristics ... remained present when variables of severity were included in the analyses Conclusion RA patients who are being treated with DMARDs, especially MTX, have a reduced risk for CVD in comparison with ... suppression of inflammation, which results in a decreased risk for CVD Competing interests Mechanisms by which DMARD use could influence the risk for CVD are poorly investigated HCQ is reported to influence...
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Báo cáo khoa học: " Accelerated high-dose radiotherapy alone or combined with either concomitant or sequential chemotherapy; treatments of choice in patients with Non-Small Cell Lung Cancer" pps
... interval for 131 patients treated with Distant-metastasis free interval for 131 patients treated with accelerated high-dose radiotherapy with or without chemotherapy Figure with sequential chemotherapy ... and in three patients the reason for interruption was not clear In patients the OTT was between 43 and 57 days, in two patients the treatment was interrupted because of oesophagitis, in three patients ... A total of 131 patients was treated with high-dose radiotherapy with or without chemotherapy In 56 cases the radiotherapy was combined with concomitant cisplatin and in 26 cases with courses of...
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Báo cáo hóa học: " Mutation or loss of Wilms’ tumor gene 1 (WT1) are not major reasons for immune escape in patients with AML receiving WT1 peptide vaccination" ppt
... specific T cells raised by vaccination, the reactivity of CD3+CD8+ T cells against WT1 126-134 peptide loaded cells was measured by intracellular IFN-g and/or TNF-a cytokine staining In of 10 patients ... binding, T cell recognition or proteasomal processing Therefore, mutation analysis was performed in both samples obtained before vaccination and during progression However, no mutation leading ... and for exclusion of dead cells the LIVE/ DEAD Fixable Violet Dead Cell Stain Kit (Molecular Probes) was used For detection of WT1 expression in leukemic blasts extracellular staining was done with...
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Báo cáo y học: "Changes of uterine blood flow after vaginal radical trachelectomy (VRT) in patients with early-stage uterine invasive cervical cancer"
... undergone vaginal RT with pelvic lymphadenectomy after delivery 3-D CT scanning was also performed in a woman with normal uterus after the delivery for the assessment of an intra-abdominal disease, ... Daily vaginal disinfection with popidone iodine, bed rest, and administration of ritodrine and an ulinastatin vaginal suppository were continued as a new follow-up modality for pregnant patients ... CT imaging of a patient with normal uterus after the delivery A: Ascending branch of right uterine artery B: Ascending branch of left uterine artery C: Descending branch of right uterine artery...
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Báo cáo sinh học: "Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib" potx
... levels declined markedly at all time points in patients with high VEGF-C concentrations at baseline, with little change in patients with low baseline VEGF-C This finding is consistent with the ... and that inhibition of this receptor may result in improved clinical outcome in a subset of patients with this disease, following treatment with sunitinib In support of the proposed role for the ... reduction from baseline in median levels of each marker was seen in patients with disease control at this time point, compared with little change in those without disease control For sVEGFR-3, the...
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Báo cáo hóa học: " Robot-aided therapy for upper limbs in patients with stroke-related lesions. Brief report of a clinical experience" ppt
... functionality for all subjects The sample had a baseline FM in line with other studies (Table 3) [10,22,23] and so was the increase in FM score (Lindmark and Hamrin) [10,22,23] All subjects showed excellent ... examination included subjects in a stable disease stage Our results are in accordance with those of Bosecker 2010, who studied 111 individuals with chronic impairment caused by stroke and trained with ... therapy with physiotherapy in the treatment of stroke patients Clin Rehabil 2009, 23:217-28 Lauretani F, Saccavini M, Zaccaria B, Agosti M, Zampolini M, Franceschini M: Rehabilitation in patients...
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báo cáo hóa học:" Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib" pot
... levels declined markedly at all time points in patients with high VEGF-C concentrations at baseline, with little change in patients with low baseline VEGF-C This finding is consistent with the ... and that inhibition of this receptor may result in improved clinical outcome in a subset of patients with this disease, following treatment with sunitinib In support of the proposed role for the ... reduction from baseline in median levels of each marker was seen in patients with disease control at this time point, compared with little change in those without disease control For sVEGFR-3, the...
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Báo cáo khoa học: "Radio-induced malignancies after breast cancer postoperative radiotherapy in patients with Li-Fraumeni syndrome" docx
... thyroid carcinoma had developed inside the irradiated volumes in 3/8 patients Experimental data highlighted the role of ionizing radiation stress in human cells harboring heterozygous germ- line p53 ... lumpectomy including a sentinel lymph node biopsy and chemotherapy with traztuzumab The p53 mutation had been diagnosed during chemotherapy Postoperative radiotherapy had therefore been cancelled ... type of germline p53 mutation for each patient The majority of the mutations were missense mutations resulting in abnormal protein function Patients and had a splicing mutation The splicing mutation...
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Báo cáo y học: "Impact of concomitant aortic regurgitation on long-term outcome after surgical aortic valve replacement in patients with severe aortic stenosis" potx
... preoperatively and 12 months after AVR in patients with AS alone in comparison with patients with AS+AR, but at 104 months LVMi was similar between the groups Mean LVEF remained unchanged in both groups throughout ... LV hypertrophy in patients with AS and coexisting significant AR, in relation to patients with isolated AS, was also noted in earlier reports [5,6] There is ongoing controversy with respect to ... patients in AS group did not have postoperative decrease in LV volume indices, whereas patients in AS+AR group experienced decrease in LV volume indices at 12 months, which was evident also after...
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báo cáo khoa học: "The importance of organizational characteristics for improving outcomes in patients with chronic disease: a systematic review of congestive heart failure" pdf
... guidance for how to approach disseminating research findings into routine care The CAS framework suggests that local contexts and local interactions between individuals are critical considerations in ... congruent with the nature of the disease or diseases of the patients being cared for Diseases may mediate the way that interventions influence a patient’s care The level of complexity of different diseases, ... review of interventions to improve outcomes for patients with Type diabetes, expanding the data regarding the importance of considering health care settings as CAS beyond a single chronic disease...
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Implementing electronic clinical reminders for lipid management in patients with ischemic heart disease in the veterans health administration: QUERI Series doc
... organizations for treating patients with IHD and called for lowering LDL-c to 100 mg/dL or less in patients with known IHD [8-10] However, research has indicated that veterans receiving primary care in ... practice guidelines for a variety of conditions and in a range of settings, but even after intervention, these studies find wide variation in guideline adherence and fail to find any specific interventions ... a dialog box with options for treatment including check boxes for direct ordering of medications (e.g., statins) In both cases, providers have the option of checking a box indicating that the...
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Báo cáo y học: " Prolonged-release melatonin versus placebo for benzodiazepine discontinuation in patients with schizop" pdf
... benzodiazepine withdrawal in schizophrenia patients We hypothesize that adding melatonin will accelerate the rate of benzodiazepine tapering off and therefore will result in reduced benzodiazepine dose ... number Blinding Trial participants as well as trial staff are blinded to the allocated treatment The blinding will be maintained by using matching placebo, and an independent unit to perform the ... directly illustrating the distribution of benzodiazepine dose in patients with schizophrenia after going through a discontinuation trial is not available in the literature In the following we apply...
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báo cáo khoa học: " Implementing electronic clinical reminders for lipid management in patients with ischemic heart disease in the veterans health administration: QUERI Series" ppsx
... organizations for treating patients with IHD and called for lowering LDL-c to 100 mg/dL or less in patients with known IHD [8-10] However, research has indicated that veterans receiving primary care in ... practice guidelines for a variety of conditions and in a range of settings, but even after intervention, these studies find wide variation in guideline adherence and fail to find any specific interventions ... a dialog box with options for treatment including check boxes for direct ordering of medications (e.g., statins) In both cases, providers have the option of checking a box indicating that the...
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Báo cáo y học: " Changes in body weight, body composition and cardiovascular risk factors after long-term nutritional intervention in patients with severe mental illness: an observational study" docx
... in weight and metabolic parameters during treatment with antipsychotics and metformin: the data inform as to potential guideline development? A systematic review of clinical studies Int J Clin ... (SD) Within-subject paired t-tests compared initial vs end point measures for subjects that completed the mo intervention Comparisons between completers and drop-outs were performed using independent ... nutritional intervention is effective in decreasing adiposity and metabolic parameters in patients with severe mental illness Previous lifestyle interventions have clearly reported weight loss in patients...
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Báo cáo y học: "The Nordic maintenance care program: what are the indications for maintenance care in patients with low back pain" pot
... relating to the indications for the use of MC For example, within this definition, it was considered unsuitable to offer MC to patients with no previous history of back problems at all, whereas patients ... 2), the information provided was not sufficiently succinct for a clear cut decision, and therefore"mainstream” answers were based on the remaining questions Page of and for the last working week ... For this scenario, the research team expected the majority to reply"no” (Table 2) Maintenance care in patients with monthly episodes of LBP but with different outcomes Information collected in...
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Báo cáo y học: "Efficacy of positive end-expiratory pressure titration after the alveolar recruitment manoeuvre in patients with acute respiratory distress syndrom" potx
... disconnected (incidentally or for bronchoscope) or if FiO2 requirement was increasing again in the patient, who showed initial improvement of oxygenation by ARM If the weaning trial was performed within ... reasonable approach to determining the appropriate level of PEEP requires maintaining PEEP-induced reopening of atelectatic areas and avoiding PEEP-induced lung overinflation Higher than traditional ... During the ARM, all patients were sedated and paralysed by continuous infusion of midazolam-ketamine and vecuronium bromide No changes were made in the doses of inotropic agents or fluid infusion...
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Báo cáo y học: " Formation of translational risk score based on correlation coefficients as an alternative to Cox regression models for predicting outcome in patients with NSCLC" doc
... (1-specificity) rates of the introduced formula applied to patients with non-small cell lung carcinoma: theoretical reference line of no discrimination, thin continuous; ROCs using T-, N-, M-status, ... staining pattern inside the stroma Positive signals were confined to macrophages, while the tumours themselves were not stained; comparable staining patterns were evident in squamous cell carcinoma ... Modelling 2011, 8:28 http://www.tbiomed.com/content/8/1/28 Inserting the realizations of the variables for any patient resulted in an individual ISIR score, with large values for ISIR indicating...
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Báo cáo y học: " Comparison of two non-bronchoscopic methods for evaluating inflammation in patients with acute hypoxaemic respiratory failure" doc
... and mini-BAL sampling techniques, indicating that these procedures cannot be used interchangeably for studying the lung inflammatory response in patients with acute hypoxaemic lung injury Introduction ... for the protein content (8 patients with ALI/ARDS without thick secretions and patients with ACLE) and in 15 patients for PMN percentage determination (9 patients with ALI/ARDS without thick ... s-Cath and mini-BAL were obtained early in the course of ALI/ARDS and ACLE (within one hour of intubation for the s-Cath and four hours for the mini-BAL) mini-BAL Mini-BAL was performed by means...
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báo cáo hóa học:" Randomized phase II study with two gemcitabine- and docetaxel-based combinations as first-line chemotherapy for metastatic non-small cell lung cancer" docx
... of vinorelbine and cisplatin versus vindesine and cisplatin ver- 15 16 sus vinorelbine alone in advanced non small cell lung cancer: results of a European multicenter trial including 612 patients ... Dose-finding, pharmacokinetic and phase II study of docetaxel in combination with gemcitabine in patients with inoperable non-small cell lung cancer Lung Cancer 2001, 33:277-287 Publish with Bio ... to platinum-related toxicity (e.g patients with pre-existing renal disease or neurotoxicity) Further studies are now needed to evaluate gemcitabine – docetaxel in combination with emerging molecular...
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Báo cáo toán học: "MAINTENANCE HORMONAL TREATMENT IMPROVES PROGRESSION FREE SURVIVAL AFTER A FIRST LINE CHEMOTHERAPY IN PATIENTS WITH METASTATIC BREAST CANCER" docx
... of first-line chemotherapy (anthracycline- and/or taxane-containing regimen versus other); previous line of hormonotherapy administered in metastatic setting before the first-line chemotherapy ... Prognostic factors in metastatic breast cancer patients obtaining objective response or disease stabilization after first-line chemotherapy with epirubicin Evidence for a positive effect of maintenance ... maintenance therapy for patients with metastatic breast cancer in complete remission following induction treatment J Clin Oncol 1998; 16 (5): 1669-1676 French Epirubicinn Study Group Epirubicin-based...
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