2 morphology of breast cancer at its earliest phase
Báo cáo sinh học: " Tumor escape and progression of HER-2/neu negative breast cancer under immune pressure" potx
... potentially negative effects of some immune responses in breast cancer Matkowski and Sheu both showed in cohorts of 88 and 24 patients with operable breast cancer, respectively, that relapse or ... HER-2/neu negative or positive breast cancers Peripheral blood T cells were isolated from patients with HER-2/neu positive (patients #7, 13, 14) or HER-2/neu negative (all other patients) breast cancers ... http://www.translational-medicine.com/content/9/1/35 Results Detection of HER-2/neu-specific IFN-g positive T cell responses in HER-2/neu negative breast cancer patients Of 12 patients with HER-2/neu negative...
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báo cáo hóa học:" Tumor escape and progression of HER-2/neu negative breast cancer under immune pressure" pdf
... potentially negative effects of some immune responses in breast cancer Matkowski and Sheu both showed in cohorts of 88 and 24 patients with operable breast cancer, respectively, that relapse or ... HER-2/neu negative or positive breast cancers Peripheral blood T cells were isolated from patients with HER-2/neu positive (patients #7, 13, 14) or HER-2/neu negative (all other patients) breast cancers ... http://www.translational-medicine.com/content/9/1/35 Results Detection of HER-2/neu-specific IFN-g positive T cell responses in HER-2/neu negative breast cancer patients Of 12 patients with HER-2/neu negative...
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Báo cáo khoa học: "Comparison of immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) assessment for Her-2 status in breast cancer" ppsx
... value of p53 and c-erb B-2 immunostaining is overrated for patients with lymph node negative breast carcinoma: a multivariate analysis of prognostic factors in 613 patients with a follow-up of 14-30 ... a cohort of 6556 breast cancer tissues Clin Breast Cancer 2004, 5(1):63-9 Dybdal N, Leiberman G, Anderson S: Determination of HER2 gene amplification by fluorescence in situ hybridization and ... Slamon DJ: Evaluation of clinical outcomes according to HER2 detection by fluorescence in situ hybridization in women with metastatic breast cancer treated with trastuzumab Clin Breast Cancer 2005,...
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báo cáo khoa học: "Sustained complete remission of human epidermal growth factor receptor 2-positive metastatic breast cancer in the liver during long-term trastuzumab (Herceptin) maintenance therapy in a woman: a case report" docx
... specific traits of a patient, will influence whether a patient achieves long-lasting remission on maintenance trastuzumab therapy We also speculate that the specific localization of breast cancer ... receptor 2; MBC: metastatic breast cancer Authors’ contributions JS collected and analyzed the data of the study and wrote the manuscript AD collected the data of the patient, and NT conceived ... therapy in human breast cancer Nat Clin Pract Oncol 2006, 3:269-280 Bernard-Marty C, Cardoso F, Piccart MJ: Facts and controversies in systemic treatment of metastatic breast cancer Oncologist...
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Tài liệu Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study pdf
... of at least 10 years; 4) had a breast examination that demonstrated no clinical evidence of cancer; 5) had a mammogram within 180 days before randomization that showed no evidence of breast cancer; ... population, rates of invasive breast cancer were calculated for several subgroups of women When age, history of LCIS, history of atypical hyperplasia, and levels of predicted risk of breast cancer ... mammographic and pathologic examination Therefore, she was not at risk for development Fig Example of a breast cancer risk profile NSABP סNational Surgical Adjuvant Breast and of breast cancer and...
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Mammography and Beyond: Developing Technologies for the Early Detection of Breast Cancer pptx
... Development of displays and workstation design for improved image interpretation Discovery of molecular profiles toward goal of precise molecular diagnosis of cancer Breast cancer is one of eight cancers ... stages of breast cancer A thorough annual physical breast examination and monthly breast self-examination can often detect tumors that are smaller than those found in the absence of such examinations, ... 22” Watercolor and ink http:/www.breastcancerfund.org/gallery_6.html Art Rage Us The Art and Outrage of Breast Cancer National Academy of Sciences National Academy of Engineering Institute of...
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Management of breast cancer in women: A national clinical guideline ppt
... treatment of breast cancer Clinical practice guidelines for the care and treatment of breast cancer: 14 The role of hormone replacement therapy in women with a previous diagnosis of breast cancer ... PJ.Validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30) as a measure of psychosocial function in Breast cancer patients Eur J Cancer ... in 17% of unirradiated or inadequately irradiated patients (17 of 102), compared with 2% of 56 irradiated patients.78 In another series, the risk of supraclavicular failure was 13% (six of 46)...
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Factors infl uencing the risk of breast cancer – established and emerging ppt
... for breast cancer, and as effect modifiers of the association of fat intake and risk of breast cancer Cancer Causes Control, 8, pp49-56 18 Collaborative Group on Hormonal Factors in Breast Cancer ... protective role of pregnancy in breast cancer Breast Cancer Res., 7(3), pp131-42 20 Collaborative Group on Hormonal Factors in Breast Cancer (2002b) Breast cancer and breastfeeding: collaborative reanalysis ... Risk of breast cancer in relation to lifetime alcohol consumption J Natl Cancer Inst., 87, pp923-929 35 Cancer Research UK (2007) About breast cancer: Breast cancer risks and causes http://www.cancerhelp.org.uk/help/default.asp?page=3285...
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Mouse models of breast cancer metastasis: Anna Fantozzi and Gerhard Christofori pdf
... MT2994 primary breast cancer cells has shown that the expression of osteopontin was associated with a constitutive activation of Page of 11 (page number not for citation purposes) Breast Cancer Research ... spreading of cancer cells to local lymph nodes via the lymphatics in human breast cancer Another important aspect to the understanding of breast cancer metastasis is the role of different subpopulations ... Relation of number of positive axillary nodes to the prognosis of patients with primary breast cancer An NSABP update Cancer 1983, 52:1551-1557 Chambers AF, Groom AC, MacDonald IC: Dissemination...
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Detection of breast cancer cells using targeted magnetic nanoparticles and ultra-sensitive magnetic field sensors potx
... characterization data RSL participated in experiment design and data interpretation ERF participated in experiment design, breast phantom measurements, calculations of source locations, data interpretation, ... implying that the saturation magnetization (M s ) is 81 J/T per kg [Fe O ], which is slightly lower than the saturation magnetization of bulk magnetite (92 J/T per kg) These data further imply that the ... then incubated in goat anti-mouse Hathaway et al Breast Cancer Research 2011, 13:R108 http:/ /breast- cancer- research.com/content/13/5/R108 IgG conjugated to Alexa 488 (Invitrogen Corporation) (diluted...
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Guidelines for the early detection and screening of breast cancer ppt
... Mediterranean Atord Modjtabai Professor of Pathology United States of America WHO Library Cataloguing in Publication Data Khatib, Oussama M.N Guidelines for the early detection and screening of breast cancer ... implementation of the guidelines Vacat page Epidemiology of breast cancer Global overview Breast cancer represents 10% of all cancers diagnosed worldwide annually and constituted 22% of all new cancers ... most common cancer in women The incidence of breast cancer in women in high-income countries in 2000 was at least twice that of any other cancer, similar to the incidence of cancer of the cervix...
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Guidelines for management of breast cancer ppt
... invasive breast cancer 23 Chapter Management of metastatic disease Staging of metastatic or recurrent breast cancer The staging evaluation of women presenting with metastatic or recurrent breast cancer ... in breast cancer (Figures 11–16) Figure 11 Phyllodes tumour of the breast 36 Guidelines for management of breast cancer Figure 12 Bilateral breast cancer Management of special problems in breast ... node-negative breast cancer Treatment policy 21 Figure Adjuvant therapy for node-positive breast cancer 22 Guidelines for management of breast cancer Definitions for response evaluation of primary...
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Reducing the Risk of Breast Cancer With Medicine: A Guide for Women potx
... screening for breast cancer It also does not cover treatments for women who already have breast cancer Risk of Breast Cancer Most women will never get breast cancer A woman’s risk of breast cancer ... breast cancer Having radiation treatment at a young age also raises the risk Learning About Breast Cancer Breast cancer is a malignant (muh-LIG-nent) tumor that starts with cells in the breast ... negative cancer It is not as common, but it is harder to treat n Raloxifene and tamoxifen reduce the risk of breast cancers that have estrogen receptors n They not reduce the risk of breast cancers...
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báo cáo hóa học:" BMP-2 signaling in ovarian cancer and its association with poor prognosis" pot
... Smad6, Snail or Wnt5a Relative fold change expression was the ratio of treated cells to that of non-treated cells Values are the mean +/- SEM of duplicate wells from at least two independent ... shown a role of BMP-2 in invasion of lung, prostate, breast cancer cells and BMP-4 in ovarian cancer [21,40,41] To confirm the role of BMP-2 in the metastatic process of ovarian cancer cells, ... proliferation of ovarian cancer cell lines We examined whether BMP-2 affects cellular proliferation of ovarian cancer cells As seen in Figure 4A, BMP-2 decreased the cellular proliferation rate of...
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báo cáo hóa học: " Experimental a-particle radioimmunotherapy of breast cancer using 227Th-labeled p-benzyl-DOTAtrastuzumab" pptx
... administration of NaCl (a) or 600 kBq/kg 227Th-trastuzumab (b) showing islands of haemopoetic cells composed of blood cells in various stages of maturation (arrow a), a great population of nucleated ... suspect that localization in bone would give a high contribution to bone marrow toxicity, but clinical studies of 223Ra have shown that it is well tolerated by breast and prostate cancer patients ... fraction of mice, which is defined as the fraction of mice that did not have to be sacrificed due to tumor diameter above 20 mm Page of 12 Evaluation of toxicity Toxicity was evaluated in all treatment...
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Automated identification of breast cancer using higher order spectra
... during my periods of leave LIST OF FIGURES Pages Figure 1.1: Anatomy of a Breast Figure 1.2: Anatomy of the Breast Figure 1.3: Benign Breast Image 14 Figure 1.4: Tumour on Left Breast 14 Figure ... the breastbone, and in many other parts of the body The lymph nodes trap bacteria, cancer cells, or other harmful substances [11] Figure 1.2: Anatomy of the Breast Breast cancer is a cancer that ... of dealing with this situation Because the breast is composed of identical tissues in males and females, breast cancer can also occur in males Incidences of breast cancer in men are approximately...
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báo cáo khoa học: "Surgical perspectives from a prospective, nonrandomized, multicenter study of breast conserving surgery and adjuvant electronic brachytherapy for the treatment of breast cancer" pps
... One-year data are available on 36 patients, with a median duration of follow up of 394 days Table Patient Demographics at Baseline Treated Patients Ineligible Patients P-Value Number of Patients ... recommendation (91% of patients) followed closely by a shortened radiation treatment time (86%) and delivery of radiation to a smaller area of the body (77%) Twelve of the patients (27%) indicated that ... rate with a steeper fall off of dose over distance [20] In prospective studies of balloon-based APBI that enrolled patients prior to surgical implantation of the balloon applicator, approximately...
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Báo cáo khoa học: "Recent advances in the surgical care of breast cancer patients" pps
... different type of organization for the treatment of breast cancer This change will be driven not much from mandatory requirements, but by the willingness of more sophisticated breast cancer patients ... false-negative cases A recent meta-analysis of 69 trials found the rate of false negatives to be about 7% of the node-positive patients [138] Much of what is known today regarding SLN biopsy in breast ... completion of lymphadenectomy [174] Recurrent Breast Cancer Approximately 10% of breast cancer patients are expected to experience an ipsilateral recurrence 10 to 15 years after their initial treatment...
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Báo cáo khoa học: "Androgen receptor status predicts response to chemotherapy, not risk of breast cancer in Indian women" doc
... risk of breast cancer associated with allele lengths of 26 CAG repeats or greater [23] On similar lines Giguere et al (2001) examined the inverse association of CAG repeat length on breast cancer ... role for AR in breast cancer outcome, AR potently inhibited ERa transactivation activity and 17b-estradiol-stimulated growth of breast cancer cells Transfection of MDA-MB-231 breast cancer cells ... domain of the AR indicated that the latter is both necessary and sufficient for inhibition of ERa signalling By binding to a subset of EREs, the AR can prevent activation of target genes that mediate...
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Báo cáo khoa học: "Ruptured gallbladder as the first presentation of breast cancer" docx
... A, Pouillart P: Infiltrating lobular carcinoma of the breast Clinicopathologic analysis of 975 cases with reference to data on conservative therapy and metastatic patterns Cancer 1996, 77(1):113-20 ... first case of breast cancer initially presenting as a gallbladder perforation We postulate that the rupture may be the result of increased pressure in the gallbladder due to obstruction of the cystic ... suspicious of cancer was subsequently discovered in the right breast and a 2.9 cm diameter lymph node was palpable in the ipsilateral axilla The patient had been unaware of these lumps Post-operative...
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