2 modulation of splenocyte phenotype and function by hucbcs
Tài liệu Báo cáo khoa học: Modulation of cyclin D1 and early growth response factor-1 gene expression in interleukin-1b-treated rat smooth muscle cells by n-6 and n-3 polyunsaturated fatty acids pdf
... synthesis and hyperphosphorylation of Rb by n-3 and n-6 PUFAs Induction of cyclin D1 is one of the earliest effects of mitogenic factors leading to cell cycle re-entry, G1-phase progression, and transition ... transduction induced by PDGF [15], serotonin [16] and thromboxane [17] As Cdk2 activity is a key event of the G1-S transition, the inhibition of Cdk2 phosphorylation and activity by EPA and DHA may explain ... (Gastrointestinal Unit, University of Pennsylvania, Philadelphia, PA, USA) Isolation and culture of rat aorta SMC Vascular SMC were isolated by enzymatic digestion of the media of thoracic aortas removed...
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Báo cáo khoa học: Modulation of Ca2+ entry and plasma membrane potential by human TRPM4b pptx
... indicated by arrow; solid lines) or untreated (dashed lines) (B) Quantitative analysis of the amplitude of Ca2+ released by ionomycin (left) and the amplitude of Ca2+ entry after readdition of Ca2+ ... Modulation of Ca2+ entry by TRPM4b A R Fliegert et al B C Fig Subcellular localization and characterization of transiently expressed TRPM4bEGFP CHO, COS-7 and HEK-293 cells were grown on coverslips and ... Journal compilation ª 2006 FEBS Modulation of Ca2+ entry by TRPM4b R Fliegert et al A B Fig Ca2+ activation and localization of TRPM4b Activation of TRPM4b by Ca2+ was analyzed in patch clamp experiments...
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Báo cáo y học: "Abnormal costimulatory phenotype and function of dendritic cells before and after the onset of severe murine lupus" pot
... model of lupus To study DCs ex vivo we performed no cell selection, to avoid any loss of DC subsets We therefore stained the entire population of splenocytes and analyzed a large number of cells by ... only by themselves and by the cytokines that are provided to them in culture (Figure 6a) We found that lupus BM-DCs expressed levels of CD40 comparable to those of BALB/c and B6 BM-DCs in terms of ... CD80 and CD86 are ligands of CD28/CTLA4 and may have different functions [29]: although both CD80 and CD86 activate effector T cells, CD80 seems to be especially important for the stimulation of...
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Báo cáo sinh học: " Protection against the allergic airway inflammation depends on the modulation of spleen dendritic cell function and induction of regulatory T cells in mice" docx
... OVA-sensitization and challenge could induced the development of airway inflammation and Th2 responses and suppressed the proliferation of peripheral CD4 +and CD8+ T cells and the expression of Foxp3+ ... over-formation of allergen-specific IgE, local hyper-production of IL-4 and IL-5 and hypo-production of INF-γ, over-expression of costimulatory molecules CD11c+CD80 +and CD11c+CD86+in spleen, and finally ... sensitized and challenged with OVA * and ** stand for the p values less than 0.05 and 0.01, respectively, as compared with PBS-vaccinated mice sensitized and challenged with PBS + and ++ stand for...
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Tài liệu Báo cáo khoa học: Modulation of F0F1-ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels pptx
... phi) before and after the addition of ADP (2 mm) to WT and CYPD KO mitochondria, and calculated on the basis of steady-state titration data by catr and olgm The activities of ANT and F0F1-ATP ... guide for the care and use of laboratory animals and were approved by the Institutional Animal Care and Use Committee of Cornell University Mice were sacriced by decapitation and livers were rapidly ... mediated by the ANT caused by alterations in matrix ATP and ADP levels as a result of changes in F0F1-ATP synthase activity by kinetic modeling The rate equation of electrogenic translocation of adenine...
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Báo cáo khoa học: Modulation of aryl hydrocarbon receptor transactivation by carbaryl, a nonconventional ligand pptx
... addition of lm of a typical AhR ligand, b-naphthoavone (BNF), and increasing concentrations of carbaryl resulted in a typical inhibition curve, with an apparent IC50 of 256.3 38.2 lm (Fig and Table ... Modulation of the interaction of AhR-LBD with CBP by AhR ligands AhR activation is at least partially mediated by the recruitment of CBP to the target promoters [29] To assess the inuence of different ... requirements of the ligand binding domain of the aryl hydrocarbon receptor for high- and low-afnity ligand binding and receptor activation Mol Pharmacol 65, 416425 29 Hankinson O (2005) Role of coactivators...
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Báo cáo khoa học: Modulation of the Arabidopsis KAT1 channel by an activator of protein kinase C in Xenopus laevis oocytes potx
... g and e), which lack Ca2+-binding sites, and atypical PKCs (aPKC; f, k ⁄ i and l), which are Ca2+-insensitive and are not activated by phorbol esters [37] Both cPKCs and nPKCs are activated by ... Phosphorylation of KAT1 channel Table Percentage of current inhibition by PKC activation Current inhibition of KAT1 and its mutants by PKC activation at 32 after PMA (mean ± SEM, n = 3–6) Replacement of T303 ... residues T306 and T308 in KAT1 Modification of T306 abolished KAT1 activity in oocyte recordings, whereas modification of T308 did not cause a loss of function [21] In animal cells, one type of Ser ⁄...
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An Analysis of Small Business and Jobs by Brian Headd Office of Advocacy pot
... Administration, Office of Advocacy, from data provided by the U.S Department of Labor, Bureau of Labor Statistics, Business Employment Dynamics Firm Size Much of the preceding discussion of job creation ... U.S Small Business Administration, Office of Advocacy, from data provided by the U.S Department of Labor, Bureau of Labor Statistics, BED and U.S Department of Commerce, Census Bureau, SUSB The ... Administration, Office of Advocacy, from data provided by the U.S Department of Labor, Bureau of Labor Statistics, Job Openings and Labor Turnover Survey Figure 10 Employment turnover is declining Share of...
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Separation of acetic acid and water by distillation effect of calcium chloride addition
... nature of the salt; amount of salt; pH of the solution from which the salt is applied; solvent for the cellulose acetate in solution; degree of hydrolysis of cellulose acetate; and the amounts of ... measure of the increase in viscosity of cellulose acetate caused by the presence of certain salts A procedure for the measurement of the salt effect has been developed The influence of salts ... because of the lack of available data on the boiling points of solutions of calcium chloride in glacial acetic acid CONCLUSIONS The results confirm the observation of Quartaroli (9) that the by the...
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báo cáo hóa học:" Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations" pdf
... on day and DC phenotype and function, as well as signs of apoptosis were characterized as described below Evaluation of DC apoptosis induced by chemotherapeutics Drug-induced apoptosis of DCs ... Figure tions Chemomodulation of phenotype of human DCs by antineoplastic chemotherapeutic agents in low noncytotoxic concentraChemomodulation of phenotype of human DCs by antineoplastic chemotherapeutic ... noncytotoxic concentrations of chemotherapeutic agents Phenotype of control and drug-treated DCs was analyzed by the expression of HLA-DR, CD83, CD80, CD86, CD40, and CD1a molecules The results...
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Báo cáo hóa học: " Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke" ppt
... 7, day 14 and day 28 by counting the number of foot faults in the left and right forelimbs The sum of foot faults (SOFFF) in the forelimbs is defined as the number of faults of right and left ... differentiation of forelimb foot faults (DOFFF) is the difference between the number of faults for the right and left forelimbs SOFFF and DOFFF were used as an index of motor deficit CSF aspiration 80 μL of ... of 95°C for 15 s, 60°C for min, and finally 95°C for 15 s, 60°C to 95°C for 30 s, and 95°C for 15 s Quantification of the gene of interest was accomplished by measuring the threshold cycles and...
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Báo cáo sinh học: " High Chromosome Number in hematological cancer cell lines is a Negative Predictor of Response to the inhibition of Aurora B and C by GSK1070916" potx
... Aurora inhibition by GSK1070916 Expression profiles of Aurora A, B, and C were evaluated in terms of response to Aurora inhibition and no association was observed (p-value = 0.79 and 0.96 respectively, ... cycle and response studies CM participated in the design of the study and performed the statistical analysis YD, MAH, CM conceived of the study, and participated in its design and coordination and ... Predictor of Response to the inhibition of Aurora B and C by GSK1070916 Journal of Translational Medicine 2011 9:110 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient...
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Báo cáo sinh học: " Inhibition of Henipavirus fusion and infection by heptad-derived peptides of the Nipah virus fusion glycoprotein" doc
... HeV and NiV infection of both Vero (Fig 5A and 5B) and PCI 13 (Fig 5C and 5D) cell cultures over a range of concentrations of the cappedNiV FC2 peptide In all cases significant inhibition of HeV ... Figure Inhibition of Hendra virus and Nipah virus infection by N-terminal and C-terminal pegylated heptad peptides Inhibition of Hendra virus and Nipah virus infection by N-terminal and C-terminal ... dissemination in the future because of availability; ease of production and dissemination; and potential for high morbidity and mortality and major health impact All of the above reasons illustrate...
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báo cáo hóa học: " Modulation of spinal cord synaptic activity by tumor necrosis factor alpha in a model of peripheral neuropathy" potx
... Modulation of spinal cord synaptic activity by tumor necrosis factor α in a model of peripheral neuropathy Diana Spicarova, Vladimir Nerandzic and Jiri Palecek Department of Functional Morphology, ... Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic Authors: Diana Spicarova, Ph.D Department of Functional Morphology, Institute of Physiology vvi, Academy of ... Coexpression of TNFR1 and TRPV1 receptor mRNA [42] and colocalization of TNFR1 and TRPV1 immunoreactivity [43] was reported in subsets of DRG neurons TNFα enhanced the sensitivity of cultured...
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o cáo hóa học:" High Chromosome Number in hematological cancer cell lines is a Negative Predictor of Response to the inhibition of Aurora B and C by GSK1070916" ppt
... Aurora inhibition by GSK1070916 Expression profiles of Aurora A, B, and C were evaluated in terms of response to Aurora inhibition and no association was observed (p-value = 0.79 and 0.96 respectively, ... cycle and response studies CM participated in the design of the study and performed the statistical analysis YD, MAH, CM conceived of the study, and participated in its design and coordination and ... Predictor of Response to the inhibition of Aurora B and C by GSK1070916 Journal of Translational Medicine 2011 9:110 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient...
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báo cáo hóa học:" Inhibition of Henipavirus fusion and infection by heptad-derived peptides of the Nipah virus fusion glycoprotein" doc
... HeV and NiV infection of both Vero (Fig 5A and 5B) and PCI 13 (Fig 5C and 5D) cell cultures over a range of concentrations of the cappedNiV FC2 peptide In all cases significant inhibition of HeV ... Figure Inhibition of Hendra virus and Nipah virus infection by N-terminal and C-terminal pegylated heptad peptides Inhibition of Hendra virus and Nipah virus infection by N-terminal and C-terminal ... dissemination in the future because of availability; ease of production and dissemination; and potential for high morbidity and mortality and major health impact All of the above reasons illustrate...
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Báo cáo hóa học: " Characteristics of functionalized nanohydroxyapatite and internalization by human epithelial cell" pdf
... USA) Page of and europium nitrate Eu(NO3) was added dropwisely into ammonium dibasic phosphate (NH ) HPO and arginine solution, and then were completely stirring and the mole ratio of Ca/P should ... until completion At the end of the experiment, the solids were collected by centrifugation (10,000 rpm/min) and filtration and then were washed thoroughly by using ethanol and deionized water The ... with a p value of less than 0.05 Results and discussion Synthesis of Arg-Eu-HAP Figure shows the TEM image of hydrothermal synthesized Arg-Eu-HAP, it can be perceived that Page of unfunctionalized...
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The Modulation of Optical Property and its Correlation with Microstructures of ZnO Nanowires ppt
... process of ZnO can be interpreted by energy band theory of semiconductor [11] When the photo energy of UV light exceeds or is equal to the band gap of ZnO crystal, some electrons in the valence band ... emission And by decreasing the diameter, the ratio of surface area to volume increased, which can favor a high level of surface and sub-surface oxygen vacancies [46] Thus, in this case, the amount of ... the existence of oxygen vacancies A structural model of hexagonal ZnO is shown in Fig 6b, in which the structure is constituted by packing of Zn atoms (red) and O atoms (blue) layer by layer in...
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The Project Gutenberg eBook, The Struggles of Brown, Jones, and Robinson, by Anthony Trollope ppt
... their coronet, their ermine, their robe of state, their cap of maintenance, their wand of office, their noli me tangere But stars and garters, caps and wands, and all other noli me tangeres, are ... DREAM THE STRUGGLES OF BROWN, JONES, AND ROBINSON CHAPTER I PREFACE BY ONE OF THE FIRM It will be observed by the literary and commercial world that, in this transaction, the name of the really responsible ... Click to ENLARGE THE STRUGGLES OF BROWN, JONES, AND ROBINSON: BY ONE OF THE FIRM EDITED BY ANTHONY TROLLOPE AUTHOR OF "FRAMLEY PARSONAGE," "THE LAST CHRONICLE OF BARSET," &c &c REPRINTED FROM...
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