... Comparison of NMR spectra of SAIL and UL At3g16450.1 Although the concentration ofthe SAIL protein was lower than that ofthe UL protein by a factor of three (SAIL, 0.2 mm; UL, 0.6 mm), the NMR ... Thus each ofthe two domains of At3g16450.1 adopts a lectin fold The orientation ofthe N-terminal domain relative to the C-terminal domain could not be defined owing to the absence of inter-domain ... from internal dynamics of these residues on the intermediate time scale for chemical shifts As a result, these are the least well-defined regions ofthe N-terminal domain The C-terminal domain...
... constants ofthe 15N nucleus ofthe distal NO and ofthe 14N nucleus ofthe proximal His ofthe GmHO-1 complex are closer to those ofthe rHO-1 complex than to those ofthe SynHO-1 complex Thus, ... ofthe heme pocket of GmHO-1 might be associated with the smaller values of Kazide for GmHO-1 and SynHO-1, and with the ferric character ofthe heme The Kimidazole values ofthe three kinds of ... against the concentration of azide of each solution The intersection point corresponding to the mole fraction of 0.5 ofthe respective forms gives the amount of azide necessary to attain the equilibrium,...
... correspond to the portion ofthe peptide crossing the membrane, whereas Shao et al [13] reported evidence that the peptide is located entirely on the outside ofthe micelles, in contact with the negatively ... to those ofthe lipid phase ofthe membrane, which promotes the formation of short-range H-bonds inducing helical structures The structural characterization of a monomeric, soluble form of Ab-(1–42) ... only to shed some light on the steps involved in the fibrillogenesis, but, most of all, to evaluate the role of Ab-(1–42) in the interaction with the membrane The structure of Ab-(1–42) found in aqueous...
... rotation ofthe monomers in individual dimers In the center there is a schematic ofthe mutual relationship ofthe monomers, in selected members ofthe family, as indicated by the twist angle ofthe ... nonarchaeal IMPases The superposition ofthe second subunit ofthe MJ0109 structure (1G0H) after superposition ofthe first subunit requires a rotation of 15° along the longest axis ofthe dimer in ... one ofthe intermediates between the human IMPase and FBPase dimer organization In the surrounding panels, clockwise, starting at the top left, are the structure ofthe tetrameric TM1415, the...
... antiparallel b-sheet in the center ofthe domain with the active site ofthe enzyme on one side and the Rieske center on the other side ofthe sheet (Fig 3) Covering one side ofthe sheet are two FEBS ... 20 A from the center ofthe funnel, they form the base ofthe b subunit (Fig 3) The last four residues in the C-terminal coil (residues 171–174) are deeply anchored inside the core ofthe conical ... catalytic domains ofthe a subunit In the heterohexamer, the Rieske domain interacts with the base ofthe adjacent b subunit and the catalytic domain ofthe adjacent a subunit Most ofthe ab interactions...
... side ofthe helix while the hydrophobic side chains of Leu42, Ile46 are on the other (Fig 7II) This helical conformation is not integrally conserved in the 20 structures as the average rmsd ofthe ... data The thickness ofthe bar for the sequential NOE data is related to the approximate intensity ofthe NOE (strong, medium and weak NOEs) Table Long range NOEs, allowing the formation ofthe ... consequence ofthe presence of TFE on the structure of Vpr is the tertiary structure may open up However, the NMR solution structure ofthe short fragment (13– 33)Vpr has been determined in presence of...
... STRUCTURE OFTHE NEW TOEIC TEST NEW TOEIC TEST SERIES Section Part Task No of Time Max score 45 mins 495 Questions 10 Question – Response ... candle: đèn cầy ; roof: mái nhà 91 measure: đo đạc 92 traffic: giao thông 93 Be operating: vận hành 94 file: tài liệu 95 Be mopping = be sweeping: quét 96 microphone: mi-cro; on the stage: sân khấu; ... Bottle (of water): chai (nước) 102 be feeding: cho ăn 103 Be sipping: nhấm nháp ngụm 104 Business card = name card: danh thiếp 105 Be folding: gập lại 106 Be pointing: (dùng tay) into the distance...
... in their homing position Each process blocked in the course of task execution relies on the other processes for removal ofthe barrier Essentially, the proof in question is a demonstration ofthe ... they are called the P-operation and the V-operation A process, "Q" say, that performs the operation " P (sem)" decreases the value ofthe semaphore called "sem" by If the resulting value ofthe ... the value ofthe semaphore called "sem" by If the resulting value ofthe semaphore concerned is positive, the V-operation in question has no further effect; if, however, the resulting value of...
... the long-term effects ofthe crash on the purchasing power ofthe currency of Country T to the immediate, more severe short-term effects ofthe crash on the purchasing power ofthe currency of ... economic theory to predict the most likely date ofthe next crash in Country T C comparing the total number of shares sold during the worst days ofthe crash in Country T to the total number of shares ... as the temperature ofthe air blown on the window increases D The warm air from the defrosting vent for the front windshield cools rapidly as it dissipates throughout the rest ofthe car E The...
... of Microsoft Corporation in the U.S.A and/or other countries The names of actual companies and products mentioned herein may be the trademarks of their respective owners Module 1: Overview of ... topic does not provide a lot of detail because these topics are not the focus ofthe course Languages in the NET Framework Mention that C# is the premier language ofthe NET Platform, and that ... Platform List the main elements ofthe NET Platform Describe the NET Framework and its components Explain the language support in the NET Framework 2 Module 1: Overview ofthe Microsoft NET Platform...
... NE2 of His31, bound to the metal, in the company of a water oxygen, from the apical positions The manga˚ nese was only 0.06 A out ofthe equatorial plane (Table 3) The angles around the metal cofactor ... [26] These findings lead to the hypothesis that Fe-bound ApeSOD mimics the product-inhibited form and the shift of Tyr39 suppresses the release ofthe peroxide product This may be one ofthe reasons ... inhibition ofthe binding ofthe superoxide substrate and the other to product inhibition by hydrogen peroxide There are two mechanisms proposed for the reaction cycle of Mn ⁄ Fe-SOD: the 5-6-5...
... to the intensification ofthe sovereign debt crisis in the euro area The pricing of risk in the repo market has become more dependent on the geographic origin of both the counterparty and the ... Avenue avoids the problems of having to define ex ante the scope of activity to be separated or prohibited Against the backdrop ofthe ongoing financial crisis and the fragility ofthe financial ... entity by the funds ofthe deposit bank, and hence limit the liability of taxpayer and the deposit insurance system; 3) avoid the excessive allocation of lending from the deposit bank to other financial...
... to the residue in the midpoint ofthe respective loop, as shown in Fig To the east ofthe active site the 37- and 60-loops border the S2¢ pocket ofthe proteinase The observed differences in the ... below) The southern boundary ofthe active site cleft of DESC1 is formed by the 145 autolysis loop The backbone of this loop differs markedly from the other serine proteinases, making the active ... that the most similar regions of these proteinases mediate interaction ofthe two b-barrels, formation ofthe catalytic machinery and structures required for binding ofthe main chain ofthe substrate...
... gray indicates the C-terminal part The dimer’s formation is established by the incorporation ofthe b8-strand of one monomer into a b-sheet ofthe other monomer The position ofthe zinc ion is ... rmsd of 1.0 A for the Ca atoms Thus, the movement ofthe a2 helix accounts for 23% ofthe rmsd value (i.e for approximately one quarter ofthe structural difference between the enzymes) These ... and determines the shape ofthe active site entry (e) The structure ofthe active site is essentially identical with the active sites ofthe MshB and LpxC proteins The conservation of catalytically...
... whereas binding of a minimum of m Mn2+ ions forms the inactive complex The sizes ofthe active and inactive fractions are the result of competitive metal binding to RNA The values of n and m are ... protected The Cr.LSU pattern is distinct in that the rst three nucleotides of P7, and the 3Â-half of J8 7, are not protected The rst three nucleotides of P7 are part ofthe G binding site, as are the ... further at GMP < 20 lm These data extend the above result, and support the conclusion that Mn2+ affects mainly the correct folding ofthe ribozyme The FEBS Journal 273 (2006) 26312644 ê 2006 The...
... confirming that the mutation of Tyr186 to Phe186 does not grossly perturb the overall framework ofthe enzyme or the active site The active sites ofthe enzymes are shown in stick format with the sigmaA ... bond in close proximity ofthe N5 atom A putative flipping motion ofthe progesterone molecule along an axis parallel to the FMN plane aligns the C1-C2 with the 4666 plane ofthe isoalloxazine ring ... re-oxidation ofthe flavin and the formation ofthe hydride-Meisenheimer complex of TNT (C) As for panel B except the spectral changes are recorded over an extended time period and show degradation of the...
... one-turn helix on the other face It is thought that the two inner strands ofthe b-sheet lie within the major groove ofthe DNA and that a hydrophobic pocket formed by the side chains of Y123 and I125 ... [18] The structure ofthe helical coil a2/a3 allows us to interpret the consequences ofthe six mutations As P153(152) and G162(161) are buried in the protein core, replacement of each of these ... cluster in these two regions Knowledge ofthe structure of a larger portion of MeCP2 including the transcriptional repression domain would resolve these speculations and clarify the role ofthe helical...
... biosynthesis of Escherichia coli Fig The complete chemical structure ofthe carbohydrate backbone ofthe LPS from Acinetobacter baumannii strain ATCC 19606 Ó FEBS 2002 [26,27] Then, the biosynthesis ... E2, and F1 and E4 The signals ofthe anomeric carbons in Kdo residues were assigned on the basis ofthe intraresidual correlations between H-3eq and C-2 The a-con®guration ofthe Kdo residues ... by the chemical shifts of their H-3ax, signals (1.7±2.3 p.p.m.) [22,23]; however, the chemical shifts of H-3ax, of C were interchanged The chemical shifts of protons H-3, H-4, H-5, and H-6 of...