07 e3710 long acting ppi as new approach for the treatment of unmet medical needs for gerd
Báo cáo y học: "Nebulised heparin: a new approach to the treatment of acute lung injury" pdf
... ‘standard’ care has to be defined in detail in such situations, and rigorous control of physiological variables as well as therapeutic modalities is of the outmost importance [9] The use of treatment ... administration as rapidly as necessary? How can dosage of the drug be titrated to achieve maximal local effects without the risk of systemic complications? What is the adequate duration of this therapy? ... work remains to be done The following questions need to be answered As the pro-coagulant state in the alveolar space begins in the early phases of ALI, how can it be assessed in order to initiate...
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Báo cáo khoa học: "Constituent-Based Morphological Parsing: A New Approach to the Problem of Word-Recognition" pdf
... suffixes as far as the phonology is concerned (i.e., they undergo Vowel Harmony with the word to which they attach) are separate words from the point of view of the syntax For instance, the auxiliary ... well-formed Also exemplary of the division of duty between the morphophonological parser and the syntactic parser is the dual status of subcategorization in Warlpiri For example, the ergative case ... constituency The task of the morphophonological parser is to f'md out where the word boundaries are and then where the morphemes are It receives as input a stream of segments and a parallel stream of suprasegmental...
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Part i organic reactions in non conventional solvents part II new approach to the formation of bishomoallylic alcohols synthesis of (r) sulcatol
... Application of Mannich bases and their derivatives in medicine Hence, the versatility of the Mannich reaction, along with the remarkable possibilities of exploiting the reactivity of Mannich bases in ... although the diastereoselectivities of the Mannich product were consistently high, the ratios of the Mannich product to the aldol side product varied The percentage of the Mannich product increased ... advances in the syntheses of Mannich bases, these being the development of extremely mild reactions conditions and the effective control of regio- and stereoselectivity.1,2,4 Modern versions of the Mannich...
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Báo cáo khoa học: "A Memory-Based Approach to the Treatment of Serial Verb Construction in Combinatory Categorial Grammar" pdf
... SVCs: the series of V1 to V3 and the series of V4 to V5 , because they not share their tenses The directional verb p©j ‘go’ performs as an adverb identi fying the outward direction of the action ... determine the grammatical function (subject or object) of arbitrary np’s in (13) from the directionality (the subject on the left and the object on the right) With these reasons, I therefore adapted the ... and the gap denoted in the forms 2d and 3d , c c respectively For example, the syntactic category 2< 3> s has a filler of type np on the left side and np np a gap of type np on the right side The...
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Báo cáo y học: " Chemokine blockade: a new era in the treatment of rheumatoid arthritis" ppsx
... to the site of infection), and the potential of inhibiting the migration of cells that are able to produce an array of proinflammatory cytokines at the site of inflammation The identification of ... time Therefore, initial proof -of- principle studies followed by well controlled studies of sufficient duration will be essential to realise the potential of chemokine blockade for the treatment of ... into the overlapping and distinct effects of chemokines and their receptors Furthermore, animal models can be used to assess the role of several pathogenic factors at various stages of disease,...
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Báo cáo y học: "A second-generation autologous chondrocyte implantation approach to the treatment of focal articular cartilage defects" ppsx
... details on the fabrication protocol of the tissueengineered cartilage graft For example, the exact cell density per volume of the construct was not given, and neither were details of the pre-surgery ... System, the Lysholm Score, the Knee Injury and Osteoarthritis Outcome Score, and the current health assessment form (36-item Short Form) of the International Knee Documentation Committee, as well as ... integration between the neo-cartilage and the surrounding host articular cartilage tissue A critical feature of the technology is the use of a gel carrier for the seeded cells to perfuse into the threedimensional...
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Báo cáo khoa học: A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles pdf
... was performed to further enhance the specificity of the antibody The antibody was preincubated with different concentrations of CatE and CatD, before a standard ELISA was performed to detect the ... previous assays, because specificity of detection was not only based on the peptide sequence but was markedly increased by the use of a monospecific antibody used to deplete CatE This type of assay ... immobilization was performed as described by the manufacturer The antiserum was applied to the column at 0.5 mLÆmin)1 and recycled overnight The column was washed with 20 column volumes of NaCl ⁄ Pi...
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Báo cáo khoa học: "A New Approach to the Mechanical Syntactic Analysis of Russian" ppt
... shall regard the tallies for the hindsight entries and the multiplicity of the printed meanings as a measure of the “goodness of fit” of our version ILLUSTRATION The chart given on the next pages ... temporary profile TP are revised—in the light of the SC—to form the Selected Profile (SP) The status flag v furnishes clues for the subsequent revision of the clause number C, and the syntactical ... integration determines the bounds of each phrase New predictions for the foresights are culled from three sources: a The temporary profile, TP, of the next string If the TP indicates that a new clause is...
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Báo cáo khoa học: The competitor-introduced Gc recruitment system, a new approach for screening affinity-enhanced proteins doc
... attached to the plasma membrane, and completely interrupted the migration of Gccyto towards the plasma membrane when the affinity constant of the competitor was equal to or greater than that of the membrane-associated ... excess amount of BFG2Z18-WT as the original affinity molecule, while the other contained a minor amount of FC3-2 as the affinity-enhanced target mutant and an excess amount of FC2-2 as the original ... used as shown in Table The screening efficiency was defined as the ratio of target cells that were obtained on the selection plate divided by the initial ratio of target cells These values were assessed...
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coats & schauberger - nature as teacher - new principles in the working of nature (1998)
... senses are in the end but cries in the wilderness Moving as it does in the realm of the phenomenal, the mind is unable to perceive the nature of the thing as such and therefore, as Kant says, ... together that their fins stuck out of the water There it was again? The dark shadow of the eagle and the miniature maelstrom The eagle had one of the largest salmon in its clutches and sailed off ... and foremost in the collapse of the so-called Law of the Conservation of Energy and consequently the Law of Gravity and all other dogma lose any rational or practical basis The solid, liquid, gaseous,...
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Báo cáo khoa học nông nghiệp " POST HARVEST MANAGEMENT AND NEW APPROACH FOR SUPPLY CHAIN SYSTEM OF CABBAGE AND WATER MELON " doc
... publication 2009/06 Bautista O and E.B Esguerra, 2 007 Postharvest technology for Southeast Asian perishable Crops edition, University of the Philippines Los Banos ... Participants have to long- term strategic vision to change conventional methods to meet the increasing demand of consumers - Recognize their dependence on each other and willing to work together to define ... treatment for cabbage Spoilage (%) after days Control 19.0 Alum 15% 3.4 Lime The table shows that saturated lime can control effectively the diseases Spoilage in alum treatment (3.4%) also was...
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Báo cáo hóa học: " A New Approach for Estimation of Instantaneous Mean Frequency of a Time-Varying Signal" doc
... frequency, then the IF need not be a frequency that appears in the spectrum of the signal If the IF is interpreted as the derivative of the phase, then the IF can extend beyond the spectral range of the ... M of the TF atoms, and the other is to check the energy of the residue RM x(t) A very high value of M and a very small value for the residual energy will decompose the signal completely at the ... because they are constructed on the basis of the properties of the signal being analyzed As mentioned before, a method for constructing a positive distribution using the spectrogram as a priori...
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Báo cáo lâm nghiệp: "New insights in the recognition of the European ash species Fraxinus excelsior L. and Fraxinus angustifolia Vahl as useful tools for forest management" pdf
... microsatellite-derived marker Then we assessed the utility of two of them, together with germination tests of intact untreated seeds and embryo/seed length ratios measurements, for distinguishing between these two ... performed using the BLAST algorithm at http://www.ncbi.nlm.nih.gov (National Center for Biotechnology Information), with programs blastn, tblastn and tblastx New primers were redefined on the ... only 16.32% of the observed variation (Fig 1) The populations from the zone of sympatry were distributed between the two groups, and the population of St-Dyé (S5) was a good example of a mixed...
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Báo cáo toán học: "A New Approach to the Dyson Coefficients" doc
... x2 xn x1 x2 xn This completes the proof Now we are ready to prove Theorem 1.2 Without loss of generality, we may assume r = and s = in Theorem 1.2 A new approach to Theorem 1.2 By (2.4) we have ... In recent years, there has been increasing interest in evaluating the coefficients of monomials M : = n xbi , where n bi = 0, in the Dyson product Based on Good’s i=1 i i=1 proof, Kadell [6] gave ... Academic Press, New York, 1975, pp 191–224 [2] F.J Dyson, Statistical theory of the energy levels of complex systems I, J Math Phys (1962), 140–156 [3] I.M Gessel and G Xin, A short proof of the Zeilberger-Bressoud...
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Báo cáo y học: "A new approach for the large-scale generation of mature dendritic cells from adherent PBMC using roller bottle technology" ppt
... maturation (Fig 2) The viability of the harvested mature DC from the roller bottles and static flasks was also assessed using 7-AAD staining of the cells prior to FACS analysis In both cases, the CD83+ ... phenotype of DC compared between the roller bottles and static flask system The numbers in the dot plots indicate the percentage of cells out of the total population of floating cells having the indicated ... roller bottles as in the static flasks Initially, this was a surprise to us, considering the dogma in the field that has emerged with the use of static culture flasks to generate DC for over 15...
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báo cáo khoa học: " Worry as a window into the lives of people who use injection drugs: a factor analysis approach" pot
... of variance accounted for by each factor) was constructed The point at which the slope of the plot changes from a rapid to a slow decline is the cut-off for the number of factors to be retained ... worry as the recognition of risk As such consideration of what people worry about has the potential to provide important "windows" into their lives by identifying the risks and challenges they ... an eigenvalue of 5.14 The second factor featured an eigenvalue of 2.02, while the third factor had an eigenvalue of 0.97 Further, there was not enough evidence to reject the hypothesis that factors...
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optimization of protein and rna detection methodologies and a new approach for manipulating protein activity in living cells
... expected, the contrast is linearly proportional to the amount of tetracysteine-GFP in the cell The slope of the linear regression of contrast versus the tetracysteine-GFP concentration normalizes for ... concentrations of BAL Moving the tetracysteine to the C-terminus of GFP had little effect on the overall contrast of HRW#KTF, and modestly improved the contrast of FLN#MEP (c) Contrast of GFP (green), ... resistance for both ReAsH and FlAsH (Fig 1.3c), while demonstrating little preference for either biarsenical and confirming the weaker dithiol resistance of ReAsH as compared to FlAsH1 Upon ReAsH labeling,...
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a new approach to the global asymptotic stability problem in a delay lotka voltrra differential equation
... applications of Theorem 4.1 for some cases when the eventually boundedness of the solutions of equation (2.1) is guaranteed by explicit conditions THEOREM 4.2 Assume that the conditions of Theorem ... is complete In the above theorem, all of the conditions are explicit except the assumption on the even- tually boundedness of the solutions of equation (2.1) In the following theorems, we give ... limsupt-++w so(t) Then for any solution for the solutions (2.6) N : [t-l(O), 00 ) -+ R+ of equation lim supN(t) t-++co (2.11, one has ? < -B’ (2.7) In the proof of the above theorem, we need the following...
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Performance management a new approach for driving business results
... the performance of Army officers was evaluated, with a focus on assessing officer ability.2 These efforts marked the first large-scale use of judgmental assessment Performance Management: A New ... Representing their Constituency Share Information Serve as a Conduit for Convincing Others about the Merits of the New System Pilot Test the System Components Realistically Assess the Organization’s ... Primer on Performance Management of the type of performance that is associated with different effectiveness levels Behavior-based performance measures improved • The BARS rating format was an important...
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Báo cáo y học: "Endoscopic Facet Debridement for the treatment of facet arthritic pain – a novel new technique
... median period of pain relief being months The range of relief for the radiofrequency group was from zero days to 16 months for all 26 patients who underwent the radiofrequency procedure Of the 14 patients ... 100% relief of their pain in 86% of the patients with a median relief period of months The range of relief varied from zero days to up to 13 months for the facet injection group None of the lumbar ... should be incapable of re-innervating the joint In this study we investigate the long- term efficacy of facet debridement for the treatment of chronic back pain originating in the facet joint MATERIALS...
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