— implications on disease phenotype and response to treatment
báo cáo hóa học:" Impact of HIV-1 viral subtype on disease progression and response to antiretroviral therapy" pot
... College London School of Medicine at Guy’s, King’s College and St Thomas’ hospitals, Weston Education Centre, 10 Cutcombe Road, London, SE5 9RJ, UK 2Health Protection Agency London, London South ... across different subtypes Conclusions There is now a clear consensus that there is a similar rate of progression and response to HAART for subtype B and the non-B subtypes, A and C, but that subtype ... study were to compare the rate of disease progression, based on rate of CD4 decline prior to ART, and the initial and subsequent virological response to ART in an ethnically diverse population in...
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Báo cáo y học: "Serum levels of autoantibodies against C-reactive protein correlate with renal disease activity and response to therapy in lupus nephritis" pps
... indices of renal disease activity and chronicity, today offers the best possibility to estimate renal disease and its response to therapy Biopsy is costly and is associated with considerable risks ... Authors' contributions CS contributed to the original idea, laboratory work, interpretation of data and manuscript writing AZ contributed to patient characterization, acquisition of data and statistics ... levels and chronic Table Renal BILAG response and the C1q/anti-CRP status demonstrated BILAG response
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Báo cáo hóa học: "Comparison of anti-CD3 and anti-CD28-coated beads with soluble anti-CD3 for expanding human T cells: Differing impact on CD8 T cell phenotype and responsiveness to restimulation" pot
... Isolation Kits purchased from Miltenyi Biotech Monitoring T cell division and early expansion using CFSE labeled cells To monitor cells division and expansion during the early days after stimulation, ... intracellular IFNg or TNFa in response to PMA/A23187 stimulation (Figure 5) T cell response to restimulation On occasion, the number of cells generated by one cycle of T cell expansion may be insufficient ... expanding poorly 3), in the absence of CD57 expression, or rapid intracellular cytokine production in response to restimulation, we suggest these cells evolve towards a phenotype analogous to...
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Báo cáo khoa học: " The effects of ectomycorrhizal status on carbon dioxide assimilation capacity, water-use efficiency and response to transplanting in seedlings of Pseudotsuga menziesii (Mirb) Franco" docx
... concentration (C calcu) i lations were performed in order to assess whether differences for A between treatments and A changes in response to transplanting were due to chloroplastic or to stomatal factors ... in treatments TtP and Tt took place only from d 11, and recovery of g was also observed in treatment LI alterations in the photosynthetic demand for CO while the supply function (related to stomatal ... and strain used as mycobiont and ii), that there may be a discrepancy between effects of mycorrhizae on stem elongation on the one hand and on diameter and weight growth on the other Tyminska et...
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Báo cáo y học: "The anti-cyclic citrullinated peptide response in tuberculosis patients is not citrulline-dependent and sensitive to treatment" ppsx
... symptoms, sicca symptoms, spontaneous abortion, history of thrombosis, and familial history of autoimmune diseases All the patients were tested for HIV, hepatitis B and C Data on the resistance of the ... healthy control sera with citrullinated and corresponding arginine-containing peptides Figure Reactivity of TB and healthy control sera with citrullinated and corresponding arginine-containing ... detection in at least a subset of infectious and other inflammatory diseases should be performed by using a combination of citrullinated and the corresponding non-citrullinated antigens Abbreviations...
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Báo cáo khoa học: "RAGE: Exacting a toll on the host in response to polymicrobial sepsis and Listeria monocytogenes" pps
... signaling systems that stimulate hyperinflammatory responses (Figure 1) In conclusion, in polymicrobial sepsis and in response to L monocytogenes, genetic deletion of RAGE is remarkably protective RAGE ... Listeria infection, the innate response is critical for early bacterial clearance and host survival The adaptive response instead is required for controlling chronic, but not acute, infection since ... al.: Receptor for advanced glycation endproducts (RAGE) regulates sepsis but not the adaptive immune response J Clin Invest 2004, 113:1641-1650 Pamer EG: Immune responses to Listeria monocytogenes...
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A study of bloating symptomatology, the role of gastrointestinal transit and the response to treatment with the 5 HT4 receptor agonist in patients with bloating predominant irritable bowel syndrome
... psychological treatment in IBS A randomized, controlled trial of IBS patients with long-standing symptoms and no response to conventional medical treatment found psychotherapy superior to medical treatment ... spontaneously induced contractions of the colon in rat leads to 18 activation of the locus coeruleus in the pons, an area closely connected to pain and emotional centers in the brain (Svensson, ... to serotonin 5-HT4 receptors are located on intrinsic primary afferent neurons, cholinergic interneurones that activate excitatory and inhibitory neurons involved in the peristaltic reflex, and...
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Tài liệu Preparedness and Response to a Mass Casualty Event Resulting from Terrorist Use of Explosives pdf
... motivated and act in ways that transcend usual organizational confines, enabling them to successfully confront challenges and barriers in communication, organization and response, standards of care, and ... scale and scope Extensive discussion and planning support linear activation and should be reserved until after the response Time constraints The response to a TUE-MCE requires rapid intervention and ... meta-leaders successfully confront challenges and barriers in communication, organizational response, standards of care, and surge capacity Meta-leaders build and maintain relationships and establish clear...
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Research on Intrusion Detection and Response: A Survey pdf
... produce and consume intrusion-related information” Where CIDF and IDAR respectively stand for “Common Intrusion Detection Framework” and “Intrusion Detection Analysis and Response Considering ... intrusions The passive IDS is only responsible for monitoring the system and to inform the administrator once an intrusion occurs or to produce an advance warning The response concept is related to ... IEEE A Zhong and C F Jia, “Study on the applications of hidden markov models to computer intrusion detection,” in Proceedings of Fifth World Congress on Intelligent Control and Automation WCICA,...
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Individual Preparedness and Response to Chemical, Radiological, Nuclear, and Biological Terrorist Attacks - A Quick Guide potx
... information and updates on RAND’s ongoing research on terrorism, please visit: http://www.rand.org/terrorism_area/ PREPARATORY ACTIONS Gain understanding of what will be required to accomplish response ... information and updates on RAND’s ongoing research on terrorism, please visit: http://www.rand.org/terrorism_area/ PREPARATORY ACTIONS Gain understanding of what will be required to accomplish response ... information and updates on RAND’s ongoing research on terrorism, please visit: http://www.rand.org/terrorism_area/ PREPARATORY ACTIONS Gain understanding of what will be required to accomplish response...
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Báo cáo sinh học: "The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil" pdf
... the potential to execute necrosis in response to treatments with glycolytic inhibitors In contrast, the bioenergetic signature directly correlates with the apoptotic response to 5-FU treatment Overall, ... activation of necrosis by metabolic catastrophe in response to treatment with these metabolic inhibitors In contrast, treatment of cells with 5-FU only marginally affected cellular ATP concentrations ... induction of apoptosis in response to 5-FU treatment Importantly, this induction of apoptosis following 5-FU treatment appears to be more pronounced in cells that rely less heavily on glycolysis...
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báo cáo hóa học:" The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil" ppt
... the potential to execute necrosis in response to treatments with glycolytic inhibitors In contrast, the bioenergetic signature directly correlates with the apoptotic response to 5-FU treatment Overall, ... activation of necrosis by metabolic catastrophe in response to treatment with these metabolic inhibitors In contrast, treatment of cells with 5-FU only marginally affected cellular ATP concentrations ... induction of apoptosis in response to 5-FU treatment Importantly, this induction of apoptosis following 5-FU treatment appears to be more pronounced in cells that rely less heavily on glycolysis...
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Báo cáo y học: "Differential expression, function and response to inflammatory stimuli of 11β-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation" pps
... response to cytokine treatment Instead, striking variations in expression were observed for the enzyme 11β-HSD1, which exhibited cell-specific and cytokine-specific variations in expression and ... expression and function are also subject to significant tissue-specific variations Differential expression of 11β-HSD1 did not appear to be due to underlying inflammatory disease in donor RA ... resolution, persistence and treatment of inflammation Conclusion Stromal cells play a pivotal role in normal, physiological inflammation and persistent inflammatory disease by expressing factors...
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Báo cáo y học: "Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-α, Oncostatin M and response to biologic therapies" ppt
... turnover was also demonstrated by increased MMP-2 and MMP-9 activity in response to IL-17A stimulation Mild proteoglycan depletion was observed in response to IL-17A stimulation visualised by loss ... Furthermore increased expression of pro-MMP-9 and both the pro and active forms of MMP-2 were demonstrated in response to IL17A stimulation (Figure 4d) Regulation of IL-17A expression by biologic therapy ... microtome sections were mounted on Superfrost slides and fixed in acetone for 10 minutes The sections were then washed and blocked with × casein for 30 minutes The sections were then washed and...
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báo cáo khoa học: " Effects of DNMT1 silencing on malignant phenotype and methylated gene expression in cervical cancer cells" pdf
... development of new and effective strategy in cervical treatment Conclusions In conclusion, our study demonstrates that DNMT1 silencing could suppress proliferation and induce apoptosis of Hela and Siha ... demethylation Hela and Siha cells were transfected with siRNA and treated with 1.0 μM 5az-dC (Sigma) respectively, and harvested at 72 h after incubation Genomic DNA was extracted and randomly sheared to ... length of 0.2-1.0 kb by sonication Dilution buffer and 60 μl Protein G Magnetic Bead suspension were added into the fragmented DNA and allowed for more than 10 of incubation DNA was then incubated...
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Báo cáo y học: "Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment" potx
... regulation of interferon (IFN) response genes upon tumor necrosis factor (TNF) blockade and clinical response to treatment Figure Differential regulation of interferon (IFN) response genes upon tumor ... necrosis factor (TNF) blockade and clinical response to treatment Patients were divided into two groups (ratio < and ratio > 1) on the basis of their IFN response upon TNF blockade and compared ... clinical response to treatment Finally, we investigated whether the treatment- induced changes in type I IFN response gene expression levels were associated with clinical response to treatment...
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Báo cáo y học: " Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy" pot
... variation that contributes to inter-individual differences in susceptibility to common diseases To address this question, we surveyed variation in six conserved non-coding elements in the Th2 cytokine ... disease risk, and to provide a model for understanding the role of non-coding variation on gene function and disease susceptibility Page of 12 (page number not for citation purposes) Respiratory Research ... atopic phenotypes Thus, in the Hutterites, variation in the IL13 gene is strongly associated with total serum IgE and allergic sensitization to mold allergens, and to a lesser extent to cockroach...
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Báo cáo y học: " Cough in adult cystic fibrosis: diagnosis and response to fundoplication" ppt
... vital component, patients with chronic cough frequently fail to respond to full acid suppression with proton pump inhibitors (PPI) and H2 blockers In the treatment of resistant chronic cough, ... spirometry and exacerbation rate as defined by an event Table 1: Medical treatment Class of drug Proton pump inhibitor BD + H2-receptor antagonists (Ranitidine) nocte Dopamine receptor antagonist (Metoclopramide, ... insufficiency continues to be major cause of morbidity and mortality.[1] The main respiratory manifestations include chronic bacterial colonisation, cough, bronchiectasis, haemoptysis, emphysema, and pneumothorax...
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Báo cáo y học: " Cost analysis of an integrated disease surveillance and response system: case of Burkina Faso, Eritrea, and Ma" pot
... investigation and verification accounted for only 2% to 18% of total IDSR cost However, primary health care centers spent 8% to 67% of the total IDSR resources on detection and treatment of disease ... analysis and feedback Response activities include field investigation and laboratory confirmation of suspected cases and treatment of confirmed cases In Burkina Faso, laboratory and treatment costs ... in lowand-middle income countries in 2001 were from communicable and parasitic diseases and maternal and nutritional conditions [1,2] In addition, the economic cost in terms of prevention, treatment, ...
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Báo cáo y học: "Association between inflammatory mediators and response to inhaled nitric oxide in a model of endotoxin-induced lung injury" docx
... et al appears to be a condition associated with blunted response to INO [7] and nonresponse to INO occurs in about one-third of patients with ARDS [8] Mechanisms of nonresponse to nitric oxide ... hours that switched from response to nonresponse, with lower ET-1 concentrations when no longer responding to INO A continuous endotoxin infusion may have led to further responders since endothelin ... Inflammatory response to endotoxin There was no difference in the endotoxin concentration in plasma at hours between responders and nonresponders, but the rapid decrease in endotoxin concentration...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25