... research andclinical purpose in order to determine the global functional outcomeof speech and voice after the treatment ofheadandneckcancer It allows quantifying the intelligibility also in severely ... rating, less than one point with respect to the regression line (see Figures and 4) Discussion During and after therapy of malignant diseases of the headand neck, communication skills are of ... extents of speech disorder (dysglossia) and voice disorder (dysphonia) after the treatment for headandneckcancer Speech Disorders in Patients with Oral Cancer Dysglossia often occurs in patients...
... radiathion therapy inheadandneck cancers: an update HeadandNeck 2007, 29:387-400 Popovtzer A, Eisbruch A: Advances in radiation therapy ofheadandneckcancer Expert Rev Anticancer Ther 2008, ... extent of tumour shown by imaging, including all involved (positive) lymph nodes MRI, andin few cases FDG-PET, were used in the delineation of GTV On the basis of the primary tumour size and involved ... 45 headandneck patients confirmed the findings of good dosimetric results andof toxicity, as well as the reliability and efficacy of the RapidArc modality as anticipated in dosimetric investigations...
... Hunter KD, Parkinson EK, Harrison PR: Profiling early headandneckcancer Nat Rev Cancer 2005, 5:127-135 Marur S, Forastiere AA: Headandneck cancer: changing epidemiology, diagnosis, and treatment ... ataxia-telangiectasia-mutated (ATM) improved radiosensitivity in rodent headandneckcancer models [14-16] In addition, superior imaging inheadandneck cancers resulted from the use of superparamagnetic iron oxide nanoparticles, ... References Tobias JS: Cancerof the headandneck Bmj 1994, 308:961-966 Amir Z, Kwan SY, Landes D, Feber T, Williams SA: Diagnostic delays inheadandneck cancers Eur J Cancer Care (Engl) 1999,...
... NHS National Institute for Clinical Excellence Guidance on Cancer Services Improving Outcomes inHeadandNeck Cancers The Manual Improving Outcomes inHeadandNeck Cancers Cancer service ... patients with headandneckcancer One of the striking characteristics ofheadandneckcancer services is the range of clinicians involved in its treatment and care, together with a variety of different ... responsible for 17% of cases ofheadandneckcancer All are relatively rare, the least rare being cancers of the salivary glands and cancers of the nasal cavity, middle ear and accessory sinuses (Table...
... Cummings B, Dawson L, Keller A, Kim J, Ringash J, Yu E, Hendler A, Waldron J: Intraobserver and interobserver variability in GTV delineation on FDG-PET-CT images ofheadandneck cancers Int ... might be useful in assigning dose intensification during IMRT Of course, the medical significance of including these additional data in the original treatment plan on final patient outcome is yet ... Variability of gross tumor volume delineation in head- and- neckcancer using CT and PET/CT fusion Int J Radiat Oncol Biol Phys 2006, 65:726-732 Black QC, Grills IS, Kestin LL, Wong CY, Wong JW, Martinez...
... http://www.ro-journal.com/content/6/1/1 Page of 25 Chao KSC, Gokhan O, Wade LT: Toxicity profile of intensity-modulated radiation therapy for headandneck carcinoma and potential role of amifostine Seminars in oncology 2003, ... Definitive Radiotherapy for Locally Advanced Head- and- NeckCancer International Journal of Radiation Oncology*Biology*Physics 2009, 73:410-415 Cooper J, Fleming ID, editors, HD: HeadandNeckCancer ... structures not involved by tumor and not at risk of subclinical disease In addition, in a previous evaluation of our hypopharynx-larynx patient cohort [22] treated with IMRT using midline sparing as...
... Urba S, Lin A, Schipper MJ, Wolf GT: Recurrences near base of skull after IMRT for head- and- neck cancer: implications for target delineation in high neckand for parotid gland sparing Int J Radiat ... Martel MK, Paulino A, Ship JA, Eisbruch A: Patterns of local-regional recurrence following parotidsparing conformal and segmental intensity-modulated radiotherapy for headandneckcancer Int J Radiat ... Low DA: Patterns of failure in patients receiving definitive and postoperative IMRT for head- and- neckcancer Int J Radiat Oncol Biol Phys 2003, 55:312-321 Puri DR, Chou W, Lee N: Intensity-modulated...
... anticancer therapy, with a broad range of inhibitors currently under investigation [3] Promising preclinical studies have prompted the development ofclinical trials testing EGFR inhibitors as singleagent ... Her-2, Her-3, and Her-4) These receptors are composed of an extra-cellular ligand-binding domain, a hydrophobic transmembrane segment, and an intracellular tyrosine kinase domain Binding to EGFR ... carcinoma of the headandneckCancer 1996, 78:1284-1292 Baumann M, Krause M: Targeting the epidermal growth factor receptor in radiotherapy: radiobiological mechanisms, preclinical and clinical...
... Boussin G, Daly N: Combined postoperative radiotherapy and weekly cisplatin infusion for locally advanced squamous cell carcinoma of the headand neck: preliminary report of a randomized trial Int ... has been defined by contouring the anatomic region of the initial primary and nodal GTV, considering the preoperative diagnostics and the clinicaland histological findings The PTV1 includes the ... regularly in our joint clinics at the Department ofHeadandNeck Surgery or Head, Neckand Maxillofacial Surgery Further follow up visits were scheduled every – months in the first years, – monthly in...
... of NeuroEngineering and Rehabilitation 2008, 5:30 Introduction The oscillations of head, trunk and pelvis during level walking are the result of a compass gait [1] If seen by an observer moving ... levels Discussion The aim of this paper was to assess differences in the ability of young and elderly women to maintain head stability during waking by controlling the head accelerations To this ... processing of the vestibular system signals, and for the consequent controlof equilibrium [2-4] In able-bodied individuals, both the lumbar and the cervical hinges play an important role in determining...
... A, Boffetta P, Winkelman R, Garfinkel L: Tobacco smoking, alcohol drinking, andcancerof the oral cavity and oropharynx among U.S veterans Cancer 1993, 72:1369-1375 Lagiou P, Georgila C, Minaki ... inheadandneckcancer patients who achieved locoregional controlHeadNeck 2000, 22:680-686 27 Alvi A, Johnson JT: Development of distant metastasis after treatment of advanced-stage headand ... locoregionally controlled headandneck cancers They found N-stage, T-stage and the localization of the tumor at hypopharynx or supraglottis to be variables increasing the incidence of DM on multivariate...
... approach in a set of 79 headandneckcancer patients We observed that RIA values increased with radiation Table Toxicity observed in 79 HeadandNeckcancer patients dose (0, 1, and Gy) and fitted ... the intraindividual and interindividual variations were determined in the four healthy donors andin the 79 patients Intraindividual variation for healthy donors was always lower than interindividual ... role in predicting radiation induced toxicity Methods Seventy nine consecutive patients with histological confirmed cell carcinoma ofheadand neck, diagnosed and treated in our institution and...
... against infection and invading connective tissue There are still very few studies applying the methods of tissue engineering to produce tracheal replacements and to examine these in vitro andin ... rates of stenosis and necrosis, of anastomotic insufficiencies, and a lack of mucociliary clearance At the end of the 1990s and the beginning of 2000, biodegradable stents were introduced in reconstructive ... complications leading to a termination of these trials were local infections and insufficiencies of anastomosis in 12 of the animals and extensive stenoses accompanied by respiratory insufficiency in seven...
... difference of antibodies used for staining or method of assessment for determination of Her3 status So far, there are no standardized methods of Her3 staining and scoring, our findings suggest ... value of c-erbB2 and other markers in patients treated with chemotherapy for recurrent headandneckcancerHeadNeck 2000, 22:599-608 33 Werkmeister R, Brandt B, Joos U: Clinical relevance of erbB-1 ... intensity and “continuity” of staining of the cell membrane[17] For quantification of Her3 staining, we scored two compartments of the cell - the cell membrane, using the same scoring system...
... difference of antibodies used for staining or method of assessment for determination of Her3 status So far, there are no standardized methods of Her3 staining and scoring, our findings suggest ... value of c-erbB2 and other markers in patients treated with chemotherapy for recurrent headandneckcancerHeadNeck 2000, 22:599-608 33 Werkmeister R, Brandt B, Joos U: Clinical relevance of erbB-1 ... intensity and “continuity” of staining of the cell membrane[17] For quantification of Her3 staining, we scored two compartments of the cell - the cell membrane, using the same scoring system...
... of the intima layer of transplant and recipient veins HSP70 expression is decreased by conventional radiation in the intima layer of arteries and the media layer of arteries and veins Anticancer ... coherence between high levels of HSP70 expression and the prevention of thickening of the intima layer of arteries and the media layer of vein from Funding The article processing charges are funded ... Reconstruction of complex radiationinduced injuries using free-tissue transfer J Reconstr Microsurg 1998, 14:337-40 Coleman IL: Management of radiation-induced soft-tissue injury to the headandneck Clin...
... regarding chemotherapy regimens and participated in manuscript writing DGF and QL performed dysphagia data collection including TNE and FEES, and delineation of swallowing structures KN and JC ... for headandneck carcinoma Oncologist 2007, 12:565-8 Rosenthal DI, Lewin JS, Eisbruch A: Prevention and treatment of dysphagia and aspiration after chemoradiation for headandneckcancer J Clin ... with headandneckcancerHeadNeck 2000, 22:474-82 Stenson KM, MacCracken E, List M, Haraf DJ, Brockstein B, Weichselbaum R, Vokes EE: Swallowing function in patients with headandneck cancer...
... irradiation of the neckand the oro- and nasopharynx Pretreatment evaluation consisted of a complete history and physical examination including endoscopy in unresectable cancers and detailed surgical and ... Schneider C, Nüsslin F, Damen EMF: A comparison of forward and inverse treatment planning for intensity-modulated radiotherapy ofheadandneckcancer Radiother Oncol 2003, 69:251-258 Page of (page number ... Robbins KT, Clayman G, Levine PA, Medina J, Sessions R, Shaha A, Som P, Wolf GT, the Committee for HeadandNeck Surgery and Oncology, American Academy of Otolaryngology -Head andNeck Surgery: Neck...
... Westin T, Kaasa S: Quality of life inheadandneckcancer patients: validation of the European Organization for Research and Treatment ofCancer Quality of Life Questionnaire-H&N35 J Clin Oncol ... European Organization for Research and Treatment ofCancer QLQC30: a quality -of- life instrument for use in international clinical trials in oncology J Natl Cancer Inst 1993, 85:365-376 Bjordal K, ... conception of the study and revised the manuscript critically WB made the analysis and interpretation of the data, and has been involved in drafting the manuscript CT participated in the design of the...
... scan findings 0* 1* 1* 1* * 1* * Bone graft lost/normal bone scan findings clinical course lost of skin/bone graft lost of skin/bone graft lost of skin/bone graft lost of skin/bone graft lost of ... clinical monitoring (92% and 75% respectively) When comparing retrospectively the three monitoring schemes, i.e clinical monitoring alone, bone scans alone andclinicaland bone scan monitoring together, ... because of thrombosis of the vein providing the skin pedicle Bone scintigraphy was normal (score 2) and the ensuing clinical course was uncomplicated Revision surgery was performed within the...