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Nghiên cứu tiến hành nhằm tổng kết thông tin về các phản ứng phản vệ được ghi nhận từ các báo cáo tự nguyện trong cơ sở dữ liệu cảnh giác dược tại Việt Nam từ năm 2010-2019.
Trung tâm DI&ADR Quốc gia - Tài liệu chia sẻ CANHGIACDUOC.ORG.VN facebook CANHGIACDUOC AI : LEKETNAP THANG 11 SO 2020 A A A TONG HQI Y HOC VI~T NAM VIETNAM MEDICAL ASSOCIATION 68A Ba Tri~u - Hoan Kie'm - Ha NQi;Tel: 024-39431866 Email: tapchiyhocvietnam@gmail.com; Webslte: tonghoiyhoc.vn _ - - MUCLUC • • T~p CHi Y HQC VII;T NAM T~P 496 - THANG 11 - so - 2020 VIETNAM MEDICAL JOURNAL N02- NOVEMBER - 2020 anh gia vai tro nQisoi bunq chan doan va dieu tr] vet thu'dng tanq rang Evaluation the role of laparoscopic in diagnostic and treatment of holow viscus perforation wounds Nguy~n Hoang Linh, Huynh Kim Khang, Ng_uy~nDuc Vd, Duong Van Hai, Nguyen Cong Minh Phl:lc hoi cong rang ora sua sau va Ion bang chup Zirconia co san Treatment anterior crown with pre-fabricated Zirconia Nguy~n Anh DU'O'ng,Vo Truong NhU'Ngoc, Ngo Van Toan Thl/c tranq hoat dQng tiem phong benh dai t9i tinh Gia Lai, giai dean 2015 - 2019 Situation of rabies vaccination in Gia Lai province, 2015-2019 Nguy~n Van Chuyen, Nguy~n Van Khai, Nguy~n Th] Minh Ngoc B~c diem lam sang va ket qua dieu tr! nQisoi cam rnau mOi bang dong di~n l:linical characteristicsand endoscopicelectrocauterytreatment outcomesof epistaxis Nghien cuu bao che vien nen Fexofenadin hydroclorid phan tan nhanh de tang hi~u qua dieu tr] vlem mOid! ung Preparation and evaluation of Fexofenadinehydrochloride rapid dispersible tablets to increasethe effectiveness for treatment of allergic rhinitis Vii Van Tu~n, Nguy~n Van B~ch Nghien cuu cai thien dQon d!nh thudc tlern Rotundin sulfat de tang tac dl,mgan than Study on improving stability of Rotundine sulfate injection to increase sedative effect 13 Ha Phuong Thao, Trin Thi Mai 16 20 Nguy~n Thi Ha, Nguy~n Van B~ch Ket qua bu'ocdau nQisoi bl:lngdieu tr! vet thu'dng cd hoanh The initial result of laparoscopictreatment diaphragm wounds 26 Nguy~n Hoang Linh, Huynh Kim Khang, Nguy~n Du-cVii, DU'ongVan Hai, Nguy~n Cong Minh Nghien cuu d~c diem lam sang va c~n lam sang cua b~nh nhan viem gan B m9n tfnh 31 du'Q'cdi'eutr! bang thuac Tenofovir l:linical characteristics of chronic hepatitis B cured by Tenofovir Da Thi Quynh, Vii Van Nga, Bid Thi Thu Hoai Banh gia rai lo~n chuyen hoa cald - phospho - PTH b~nh nhan 19Cmau chu ky t9i a 35 Khoath~n Tiet ni~u - L9Cmau, B~nh vi~n Huu Nghi Evaluating the metabolism trouble in dialysis patients at neuphrourology - dialysis department, Huu Nghi Hopital Trinh Thi Thanh H~ng, Nguy~n Van Tin, Nguy~n Th~ Anh 10 Khao sat sl/ tuan thu dieu tri Tenofovir tren b~nh nhan viem gan B m~n tfnh Investigation of Tenofovir treatment adherence in chronJchepatitis B patients 39 Vii Van Nga, Do Thj Quynh, Vii Thj ThO'm, Le Thj Di~m HAng, Bui Thj Thu Hoai 11 O'ng dl:lng ky thu~t multiplex PCRphat hi~n cac gen mcr-1, mcr-2 va mcr-5 khang colistin cac chung Escherichiacoli phan I~p tu cac trang tr9i ga Ha Nam Application of the multiplex PCRtechnology for detection of colistin resistant mcr-1, mcr-2 and mcr-5 genes in the Escherichiacoli strains isolated from the chicken farms in Ha Nam a a 43 Hoang Thi }\1aiHU'O'ng,Hoang Thj An Ha, Vii Nhi Ha, Hoang Thj L~an, Phung The Khang, Ph~m Duy Thai, Trin Huy Hoang a 12 Banh qia tlnh tranq nhiem virus viem qan B, C b~nh nhan 19Cmau chu ky t9i khoa Th~n tiet ni~u-19Cmau, B~nh vi~n Huu Nghi Infection with hepatitis Band C virus in dinalysis patients at the nephrology-dialysis department, Huu Nqhi Hospital , Nguy~n Van Tin, Trinh Thi• Thanh x Han!! Hoan!! Manh Tron!! • X I Nguyen Le Hoa, Nguyen The Anh 48 Trung tâm DI&ADR Quốc gia - Tài liệu chia sẻ CANHGIACDUOC.ORG.VN facebook CANHGIACDUOC - - - - - _ 13 Thl/c tranq kern khoanq hoa men rang ham Ion - rang ctra nhorn h9Csinh 12-15 51 tuoi t~i tinh Binh Dlnh narn 2019-2020 The current situation of molar incisor hypomineralistaton in group of 12-15 years old students in Binh Dinh province in 2019-2020 _ 14 Mqt so d~c diem dkh te Nguy~n Phuc Minh, Vo Truong NhU'NgQc hoc cac ca tu vong benh dai tai tinh Sdn La (2015 - 2019) 55 Some epidemiologicalcharacteristicsof human rabiesin Son La province (2015 - 2019) Nguy~n Van Chuyen, Nguy~n Van Ba, Hoang Th] Thuan 15 Thay dOi tham my m~t nha voi ph§u thuat phoi hop dich chuyen tien ham va tao 59 Simulataneuos premaxilla osteotomy and genioplasty on the attractiveness of patients with convex face facial profile DB Tuin Ngoc, But Huu Phurrc, ve Hang Lie~, Hoang Tuin Anh 16 So sanh ke't qua dieu tr] dom nau anh sang cua Laser nano giay Q-Switched Nd: YAG 63 532 nm va Laser pico giay nd: YAG532 nm Q-Switched double frequency Nd:YAG 532-nm nanosecond Laser vs double frequency Nd:YAG532-nm picosecond laser for the treatment of solar lentigines Pham Thj Mai Trinh, Le Hfru Doanh, ve Thai Ha 17 B~c diem di can h~ch bach huvet vung co ung thu bieu ma tuyen giap bi~t hoa 68 Characteristics of cervical lymph node metastasisin differentiated thyroid cancer Nguy~n Van Nam, TrAn Xuan BQ Vii Anh Hai, Le Thi Tuy~t Nhung 18 Mqt so d~c diem lam sang va c~n lam sang cua rang ham seraham tren co b~nh 1'1 71 ho~i tU mqt nhom b~nh nhan den kham t~i B~nh vi~n Rang Ham M~t Trung L(dng Ha Nqi nam 2019 Clinical and radiographic evaluation of primary upper molars with necrotic pulp of young patients at Hanoi National Hospital of odonto-stomatology Le NgQcDi~p, VOTruong Nhu NgQc, Ph~m Hoang Tuin, Nguy~n Thi Van Anh 19 Mqt so d~c diem dich t~ h9Cvi khuan Rickettsia Mien sac Vi~t Nam 75 Epidemiological characteristics of Rickettsia in North Vietnam LuO'ngThi HAng Nhung, Nguy~n Vii Trung, Le Thi HQi, Ma Thi Huyin 20 Thl/c tr~ng tai n~n thL(dng tfch cua tre nh~p khoa cap cuu t~i B~nh vi~n Nhi Trung L(dngtU' 7/2019 - 6/2020 Situation of children's injury admitted the emergency department at viet nam National Children's Hospital from 7/2019 - 6/2020 79 Nguy~n Thi Huyin Sam, Truong Thi Mai HAng 21 Banh gia ket qua ph§u thu~t dieu tri h~p dqng m~ch canh ngoai S9 t~i B~nh vi~n Da khoa Dong Nai Results of extracranial carotid artery endarterectomy in Dong Nai Province Hospital 82 Tr~n Quy~t Ti~n, Nguy~n Anh Diing 22 Hi~u qua rna hinh phl:1Choi chuc nang dl/a vao cQngdong cho ngL(Oikhuyet t~t v~n dQngt~i huy~n Thong Nhat tinh Dong Nai The effectiveness of community-based rehabilitation for people with mobility disabilities in thong nhat district Dong Nai Province 86 Nguy~n HAng Quang, Nguy~n Xuan Bai, Ph~m Van TrQng 23 Ket qua ph§u thu~t nQisoi cat rUQtthLtaqua dL(ongam d~o The results of laparoscopic appendectomy through vaginal route DB Tit Thanh, Tr~n Binh Giang 90 Trung tâm DI&ADR Quốc gia - Tài liệu chia sẻ CANHGIACDUOC.ORG.VN facebook CANHGIACDUOC hlnh cam 24 Kha nang cung ung dich vu cham soc tre so sinh tal Trung tam Y te huyen Kim Boi, tinh Hoa Binh, narn 2019 Infant care service delivery providing at Kim Boi District health center in Hoa Binh Province in 2019 93 25 Cck yeu to dlj bao ket cue d benh nhan dQt quy thleu rnau nao cec bQ cap tfnh du''c 97 dieu tr] tai tu'oi mau bang lay huyet khoi cd hoc ket hop d~t stent cap ciru thuoc tuan hoan nao truce Outcome forecast factors in patient with acute ischemic stroke received reperfusin treatment using mechanical thromboembolism combined with anterior cerebral circulation emergency stent Nguy~n Van Huy, Mai Duy Ton, Le HAng Trung Dito Vi~t Phuong, Vii Dang LU'U,Tdn Anh Tu~n bunq va mQt yeu to nguy co benh nhan n~ng nh~p vi~n 26 Tinh hinh tang ap luc khoa Hoi sire Tfch cue Intra-abdominal hypertension and some risk factors in patients who admitted to the intensive care unit 102 D~ng Th] Huong, Dao Xuan CO' 27 Hoi tu'dng quan giG'a ap luc nQi SQva diem glassgow d b~nh nhan xuat huyet nao dau Correlation between the intrcranial pressure and glassgow score in patients with brain hemorrhage for the first days Le Thi Bich Thiiy, ~guy~n 105 Van ChU'O'llg 28 KhilO sat cac yeu to lien quan den muc dQ n~ng cua b~nh gan nhiem ma khong ru''u 109 Related factors of severe nonalcoholic fatty liver disease Vo Duy Thong, D6 Duc Minh 29 Tinh tr~mg trCing qua huyet ap Iu'u dQng d b~nh nhan IQcth~n Dipper pattern on ambulatory blood pressure monitoring in the hemolysis patients 113 Chau Huu HAu, Nguy~n Minh Tri 30 KhilO sat ta du'Q'cdong kho cho cong thl)'C bao che thuoc tiem dong kho liposome amphotericin B Investigation lyophilized excipients for the preparation formulation of liposomal amphotericin B for lyophilized injection 117 Nguy~n Tu~n Quang, Ph~m Thi Minh Hu~, Nguy~n Thai SO'll 31 HQt so yeu to lien quan toi thai gian dieu trl cua ngu'ai b~nh viem loet giac mi;lc Factors related to treatment duration in patients with corneal ulcer 120 D~ng Thi Hai Hit, Ph~m HAng Van 32 Banh gia hi~u qua kiem soat ho hap cua phu'dng phap thong khf ap Iljc du'dng ngat quang dau trung tam ket h'p ngoi;li vi ph§u thu~t ti;lo hinh khf quan Evaluate the effectiveness of airway management using distal tracheal intubation and intermittent positive pressure ventilation for tracheal resection and reconstruction surgery Dinh Thi Thu Trang, Nguy~n Minh Ly, Cong Quy~t Thing, TAng Xuan Hung 33 Thljc tri;lng dam bao thuoc thong qua hinh thuc dau thau ti;li B~nh vi~n Quan Y 105 tlt nam 2015 - 2018 Current situation of drug security through drug bidding at 105th military hospital from 2015 to 2018 HACanhH~u, Nguy~n Minh Chinh, Hoang Hai, Nguy~n CAm Van, Vii NgQcMai 123 128 Trung tâm DI&ADR Quốc gia - Tài liệu chia sẻ CANHGIACDUOC.ORG.VN facebook CANHGIACDUOC Nguy~n QuAc Ti~n, Nguy~n Quang T,!, Nguy~n Dang Vtmg, Pham Hai Thanh, Nguy~n Huu Thing 132 35 136 36 139 aa 37 38 142 145 ve 39 40 41 42 Da 43 44 149 153 157 160 " 164 168 Trung tâm DI&ADR Quốc gia - Tài liệu chia sẻ CANHGIACDUOC.ORG.VN facebook CANHGIACDUOC cuu d~c diem lal}l sang due the thuv tinh sau chan thu'dng va mQt so yeu to tien hrono thi nrc sau ohau thuat dieu tri Clinical characteristics and prognostic factors for visual outcome of traumatic cataract Pham Phuong Dung, Th§m Truong Khanh Van 8anh gia ket qua phuc hoi chuc nang nh~n tmrc cho benh nhan chan thu'dng S9 nao tal B~nhvi~n Phuc hoi Chuc nang Ha NQinarn 2019 - 2020 Functional cognitive assessmentof the patient after traumatic brain injury Phan Thi Ki~u Loan, Ph~m Van Minh Banh gia hi~u qua phuc hoi chirc nang thang bang tren ngu'oi benh nhoi rnau nao t1;li B~nhvi~n Lao khoa Trung u'dng Assessment the effectiveness of balance rehabilitation for patients after cerebral infarction at National Geriatric Hospital Thi HUiYDgMinh, Cao Minh Chau B~c diem lam sang va c~n lam sang cua benh nhan tnrot dot song don tang khuyet eo Clinical and subclinical of patients with one-level lumbar spondylolisthesis Tdn HBng Vinh, Nguy~n Van Thach, Vii Van Hoe Khao sat chi so FIB-4 dl,( doan gian tinh mach thirc quan d b~nh nhan xd gan co chu'ang Investigation apri indicator to predict esophageal varices in cirrhosis patients with ascites Duy Thong, HAThi Van Anh Thl/c tranq ngu'oi khuyet t~t v~n dQng va phuc hoi chirc nang cho ngu'oi khuyet t~t v~n dQngdl/a vao cQngdong tc;lihuy~n Thong Nhat tinh Dong Nai The current situation and community-based rehabilitation for people with mobility disabilities in Thong Nhat district Dong Nai Province Nguy~n HAng Quang, Nguy~n Xuan Bai, Ph~m Van TrQng Danh gia chat 1u'Q'ng khOitieu (au quatrlnh baoquanva moi lien quan giO'acu'ong dQhuynh quang vai doi song cua tieu cau du'Q'csan xua'tbang phu'dngphap buffy coat Assessment the quality of platelets during storage period and the colleration between the fluorescence intesity and the lifetime of platelets produced by buffy coat method Nguy~n Thj Lan, Luu Thj Thu Phuong,Tr§n Van Tinh, Nguyin Dac Thao, Tr§n Thj Thanh Tam Nhu cau cham soc dai hc;lncua ngu'oi cao tuoi d mQt so xa thuQc huy~n Soc Sdn, Ha NQinam 2018 - 2019 tong-term care need of elders in some wards in SocSon district, Ha Noi in 2018 - 2019 Nguyin Thi Thu Huy~n, Ph~m Le Tuin Phau thu~t ung thu'tuyen giap d ngu'Oib~nh Basedowtc;IiB~nhvi~n NQitiet Trung u'dng Thyroid cancer surgery in patients with Basedowdisease at the National Hospital of endocrinology ' , Ph~m Quyet Thang, Tran NgQc Luong Thanh Cong, Truong Quang Huy Banh gia cau truc vi the va dQ ben cua ma van tim lQ'nsau bao quan Ic;lnhsau Evaluation of the microstructure and tensile strength of the cryopreserved porcine heart valve Cu Thj Bich Thuy, Ngo Duy Thin, Duong Cong Nguyen, Le Thj HAng Nhung, M§u Van Cal!h Kinh nghi~m bu'ac dau sU'dl,lng du'ong lIlo it xam Ian qua md ngl/c phai ph§u thu~t thay van hai 113 tc;liB~nh vi~n ChQ'Ray Early experience of minimal invasive surgery by the right thoracotomy in mitral valve replacement at the cardiac surgery deparment of Cho Ray Hospital Lam Tri~u Phat, TrAn Quy~t Ti~n 34 Nghien 46 47 48 49 50 5! 52 53 54 55 2011- 2014 Applying experimental laparoscopic appendectomy throu~h vaginal route on pig D6 Tat Thanh, Trin Blnh Giang Kha nang cung lIng dich vu cham soc SlICkhoe so sinh tal cac Tram Y te xa, huy~n Kim BOi,tinh Hoa Blnh, nam 2019 Ability to provide neonatal medical health care services at commune healthcare stations at Kim Boi Provine, Hoa Binh District, 2019 Nguy~n Qu6c Ti~n, Nguy~n Quang Tu, Nguy~n Dang Vu'ng, Pham Hai Thanh, Nguy~n Hfru Thi~g Banh gia ket qua phau thuat cat amidan bang dao Ligasure The evaluation results of tonsillectomy method with Ligasure Nguy~n Phuong Thao, Nguy~n Quang Trung Nghil~nClIUsir thay doi the tfch the chai tren hinh anh c9n9 hu'ang tir a benh nhan nghi~n ruou Research on change in volumes of corpus callosum on magnetic resonance imaging of the alcoholic patient Le Phi Dlili, Nguyen Thi Sinh, Tran Ngoc Anh, D~ng Ti~n Truong B~c diem lam sang, chan doan hinh anh b~nh Iy d!ch nao vo nen S9 sau chan thu'dng S9nao t~i B~nh vi~n Vi~t £)lIC «;Iinical characteristics and imaging evaluation of cerebrospinal liquid leak (csf) caused by skull base fracture post traumatic injury in Viet Duc Hospital _ Ngo Manh Hung, TrAn Blnh Ngoc, Nguyjn Duc Dong Banh gia tinh tranq nhiem khuan b~nh vi~n a b~nh nhan du'qc dieu tr! ECMOt~i B~nhvi~n B~ch Mai Evaluate hospital associated infections in patients who were on ECMOat Bach Mai Hospital Trin Duc Trung, Dao Xuan CO' C.c3c yeu to anh huang ket qua dieu tr! viem loet d~ day ta trang helicobacter pylori du'dng tfnh bang phac thuoc Amoxicilin, Levofloxancin, PPI t~i B~nh vi~n Trung U:dnaThai Nauven Clinical factors influencing the efficacy of H.pylori eradication of triple therpy (Amoxicilin, Levofloxancin, PPI) in Thai Nguyen General Hospital Ngo Duc hQ'P, Duong HAng Thai, Nguy~n Thj Thu Huy~n Tinh hinh nhi~m nam Malasseziatren benh nhan viem da cd dia tai Benh vien Da Ii~u Trung u'dng Malassezla infection in patient with atopic dermatitis at National Hospital dermatology and venerology Nguy~n Van Hi~u, Trin CAm Van, Phlilm 'fhi Minh Phuong Banh gia ket qua hoax~ tri dong thai tjen phauungthu' bieurna thl/c quan 1/3 giO'adu'Oi Assessment of the rusults of preoperative chemoradiotherapy for esophageal cancer Phlilm Quang Anh, VO Van Xuan Banh gia d9C tfnh ban tru'ang di ~n tren h~ t~o huyet cua vien nang ClIng Fucolen sau bao che tren d9n9 v~t thl/c nghi~m Examines the semi-chronic toxicities of Fucolenon experimental animals Trin Thanh Huong, TrAn Van Thuin, Vii Mlilnh TuAn, Nguy@n Van Khiem, Dao Van Tu, Nguy~n Ti~n Quang Nh~n xet ket qua sau tuan dieu tr! Esomeprazoletrong viem diil day khang kern theo loet a tre nhi~m Helicobacter Pylori tiili B~nhvi~n Nhi Trung u'dng Assesment of treatment result with esomeprazole after weeks for non- ulcer gastritiS combined Helicobacter Pylori infection in vietnam national Hospital'SChildr~n DilO Thj Ngoan, Phan Thj Hien 173 176 179 182 185 188 193 197 201 205 210 Trung tâm DI&ADR Quốc gia - Tài liệu chia sẻ CANHGIACDUOC.ORG.VN facebook CANHGIACDUOC 45 U'ng dunq thuc nqhlern phau thuat n9i soi qua duang am dao tren lon giai doan 56 B~c diem lam sang c~n lam sang va thai gian song them khang benh ung thir bieu 214 ma tuyen che nhay de day giai doan II, III Clinical characteristics and complementary examination, disease free survival and some factor affect disease survival of mucious gastric cancer stage II-III Nguy~n Thi H~ng, Trinh Le Huy, Le Van Thimh 57 B~c diem lam sang va m9t so yeu to lien quan den b~nh vlem da dau tal B~nh vi~n 218 Truong Th] Thanh Huong, Nguy~n Huu Sau, Trin cim Van 58 B~c diem lam sang va nhu cau cham soc dieu du'ong dau cua ngu'ai benh 221 c6 h9i chung cai nrou Clinical characteristics and needs for care in the first day of of patients with alcohol withdrawal syndrome DB Thi Hoa, Nguy~n Doan Phuong, Le Thi Thu Ha, Nguy~n Th] Hila, Pham Xuan Thing 59 Ket qua sam ph§u thuat teo ruot non bam sinh tal B~nh vi~n HO'unqhl Vi~t Duc giai 225 doan 2017 - 2019 Results of surgical treatment for jejunoileal atresia in infant at Viet Duc University Hospital from 2017 to 2019 Chu Minh Phuc, Nguy~n Vi~t Hoa, Vii Hang Tuan 60 Bi~u qua dieu tri cua colchcin may day man tfnh til phat 229 Colchicine in the treatment vietnamese patient with chronic spontaneous urticaria Ngo Th] Minh Nguy~t, Pham Thj Lan 61 Banh gia ket qua dieu tr] Erlotinib bu'ac m9t tren benh nhan ung thu' phoi khang te 233 bim nho giai dOe;!niv c6 d9t bien EGFR Assessment treatment outcome of first-line Erlotinib in patients with advanced EGFR mutation-positive non-small-cell lung cancer Nghiem TrAn VU'Q'Ilg,Nguy~n Ti~n Quang, Le Thi Y~n 62 Trai nghi~m cua giang vien ve chu'dngtrlnh giao dl,lcdieu du'ong dy'a vao nang h!c 237 Perceived experiences of nurse educators in a competency - ba.sed nursing curriculum: a qualitative descriptive study Nguy~n Thi HAng Anh, Ph~m Thi Thuy Dung 63 Thl/c tre;!ngtiem chung day du va dung lich cua tre em du'ai tuoi t9i huy~n Tr9m 241 Tau, tinh Yen Bai nam 2019 The fully and scheduled immunized situation among under 1-year-old children in Tram Tau district, Yen Bai province in 2019 Cao Bach, LQCThi Mai, Le Thi Thanh Xuan 64 Ket qua dieu tri soi ni~u quan 1/3 du'ai bangTamsulosinti;li B~nhvi~n De;!ihQcY Ha N9i 245 Results of therapy of therapy of under 1/3 by Tamsulosin treatment in Hospital University of Hanoi Trinh Anh Tu§n, Vii Nguy~n Khai Ca 65 Gia tri cua tY I~ dau nang noan (FORT)vai ket qua kfch thfch buang trung Use of follicular output rate (FORT)to predict ovarian stimulation outcome 248 Ph,m Thi Anh, Nguy~n Lien PhU'ong, LU'UQuynh HU'ong, HA Sy Hung 66 Khao sat cau truc vi the tinh machtinh cua nhO'nqbenh nhan qian tinh mi;lchtinh Evaluating the microstructure of veinous walls in patients with varicocele Nguy~n Hoai Bic, Dinh Van Toan, Ph,m ThuAn M,nh, Hoang Long 252 Trung tâm DI&ADR Quốc gia - Tài liệu chia sẻ CANHGIACDUOC.ORG.VN facebook CANHGIACDUOC Da Ii~u Trung u'dng Clinical manifestations and several factors relating to seborrheic dermatitis in National Hospital of Dermatology and Venereology 67 Hi~u qua khU'te bao mang nqoel tim bo bang Sodium Dodecy Sulfate Decellularized effect and extracellular structure of bovine pericardium after treatment with Sodium Dodecy Sulfate 256 Nguy~n Van Hoang, Ngo Duy Thin, Miu Van Canh i.e Thi HAng Nhung, Le Phu Tai, Nguy~n Cdng Long 69 Khao sat tinh tri;!ngnhiemkhuantiet ni~u benh nhantrong thang aau saughepth~n Investigationof the urinary tract infections in kidney transplant recipents in the first months after transplantation in bach mai hospital 263 Hoang Thi Nhan, Mai Thi Hiin, Nguy~n Thi Hmrng 70 Hi~u qua cua phu'dng thirc AVAPS0 benh nhan dac diem lam sang, can lam s,~ngv~ c~u'cDang t~on~ kh.iyh~i (1 benh nhan xo cl1ng bl h~ thong, LUi;lnan tien Sly hoc, f>ai hoc Y Ha NQi, N S Goh et al., 2008, Interstitial lung disease in systemic sclerosis: a simple staging system, Am J RespirCrit Care Med, 177, 11, 1248-54 , ,? A' sa TONG KET CAC BAO CAO LIEN QUAN DEN PHAN VE TRONG CO' ,nCr LIEU BAo cAo TU' NGUYEN VIET NAM GIAI DOAN 2010-2019 Truong Th] Mint, Nguy~n Phuong Thuy\ Nguy~n Hoang Anh2, D~ng Bieh Vi~t2,Cao Thj Thu Huy~n2, Nguy~n Hoang Anh', , Vii Dlnh Hoa2, Nguy~n Van Dinh3 T6MTAT Nghien oru du'gc tien hanh nham tong ket thong tin ve cac phan ung phan v~ du'gc ghi nh~n tlt cac bao cao tlj nguy~n cd so dO'Ii~u canh giac du'dc t~i Vi~t Nam tlt nam 2010 den 2019 Cac bao cao tv' nguy~n du'gc sang IQ.cdu cac thong tin yeu cau cho qua trinh danh gia phim ung theo tieu chuan dinh tru'ck f>~cdiem cua hOi;ltdQng bao cao, d~c diem cua thuoc nghi ngo va phim ung phim v~ du'gc ghi nh~n cling voi t~o.ng tin ve tri ti;li ddn vi dieu tri du'gc tong ket va mo ta Ket qua cho thay phan v~ chiem 13,7% so bao cao tv' nguy~n ADR ti;li Vi~t Nam f>dn vi bao cao chu yeu thuQc khoi cong I~p (94,5%) Du'qc 59 la doi tu'gng bao cao phan v~ nhieu nhat (41,4%) Co 81,8% bao cao ghi nh~n thong tin khai thac tien sU' di ung co 1,6% b~nh nhan co tien sU'di ((ng voi thuoc nghi ngo va 2,0% b~nh nhan co tien su di U'ngthuoc cling nhom vOi thuoc nghi n90 Khang sinh cephalosporinva carbapenem (51,5% tong so bao cao phan v~), khang sinh penicilin (9,5%), thuDc can quang (5,3°~o),N~,!\IDs t5,oo/~}la ~hO'n~nhom}h~§c du'gc bao cao nhlE:~u nhat Cac tn~u chl1ng bien nhat cua phan v~ la tren tuan hoan ~75,2%}, ho hap (74,6%), da/niem mi;lc (55,6%) Co 38,4% tru'ong hgp co bieu hi~n hi;l huyet ap nghiem trQng, 67,9% tru'ong hqp du'gc can bQy te danh gia la nghiem trQng va co 1,6% tru'ong hgp t(t vong Corticoid (72,7%) va adrenalin (68,2%) la thuDCdu'gc su dl,mg bien xu ) Tfllt7ng Cao Dang DI.I(fc 7W Hai Dl.ldng 2Trung tam DI&ADR QG, Trl.lt7ng D~i h9C DI.I(fc Ha N9i 3Mnh v$n Quifc te'Vinmec Times City, D9i t'9C VinUniversity Chiu trach nhi~m chinh: Tru'dng Thi Man Email: vudinhhoa@gmail.com Ngay nh~n bai: 24.9.2020 Ngay phan bi~n khoa hQc: 30.10.2020 Ngay duy~t bai: 11.11.2020 nhat de xU'tri phan v~ Ket qua nghien ciru cung cap thong tin can thiet cho hoat dQng theo doi va xU' tri phan v~ ti;li cac don vi dieu tri cung nhu' gqi y cho cac giai phap can thi~p cua cac cac cd quan quan Iy doi voi bien cO'y khoa nghiem trQng Til' khoa: phan ung phan v~, bao cao ADR, ti Ie bao cao, xII tri phan v~, adrenalin SUMMARY ANAPHYLACTIC REACTIONS IN SPONTANEOUS REPORTING DATABASE OF VIETNAM FROM 2010 TO 2019 The current study analyses information of anaphylatic reactions (AR) based on spontaneous reports to National Pharmacovigilance Center from 2010 to 2019 Individual Case Safety Report (ICSR) were screened for essential information and the AR was assessed followed a prespecified criteria The characteristic of reporting activity, suspected medications and reported reactions were summarized and described The reported AR were in 13,7% of spontaneous ICSR in Vietnam The public sector had major contribution, accounting for 94.5% Pharmacists were most active reporters contributing to 41,4% of ICSR.The history of allergy was reported in 81,8% of cases Of those, allergic to suspected medications or allergiC to medications which might cross reactivity with the suspected one were 1,6%· and 2,0% respectively The leading suspected medications were cephalosporins and carbapenems (51,5%), penicilin (9,5%), contrast media agents (5,3%) and NSAIDs (5,O%) The manifestations of RA occurred mainly in cardiovascular, repiratory and subcutaneous systems with prevalence of 75,2%, 74,6% and 55,6%, respectively} Severe hypotension was reported in 38,4% of cases Servere reactions have been identified by reporters in 67,9% of reports, and the fatality rate was of 1,6% Adrenalin and corticoid were 323 Trung tâm DI&ADR Quốc gia - Tài liệu chia sẻ CANHGIACDUOC.ORG.VN facebook CANHGIACDUOC TAP CHi Y HOC VIET NAM TAp 496 - THANG 11 - MEDICAL JOURNAL used to manage AR in 72,7% and 68,2% of patients, respectively), This study provides information for the management of anaphylatic reactions in healthcare centers and suggests for the intervention of authority, Keywords: Anaphylactic reaction, ADR report, reportingproportion,anaphylaxismanagement,adrenalin I £>AT VAN £>E v '" '"' Philn v~ la mQt phan ((ng di ((ng toan than, cap tinh xily sau tiep xuc voi di nguyen Day du'qc coi la mQt nhG'ngphan ((ng nguy hiem nhat tren lam sang thai gian khoi phat nhanh, c6 the gay t(( vong va khong the dl/ doan du'qc Trong cac nguon dG' Ii~u ve philn v~, bao cilO tl/ nguy~n ve philn ((ng co hc;licua thuoc (ADR) du'qc coi la n~uon thong tin quan trQng giup danh gia d~c diem cGng nhu' sl/ hinh tin hi~u philn v~ Ti;!i Vi~t Nam, theo nghien c((u cua Le Thi Thuy Linh, so Iu'qng bao cao philn v~ giai dOc;ln2010-2014 ta 2.161 ca, chiem 10,55% tong so bao cao ADR [2] Trong giai dOc;ln20102016, Nguyen Khac DGng va cQng sl/ ghi nh~n 55 bao cao philn v~ gU1ve Trung tam DI&ADR QUocgia la 4.873 ca, chiem 13,2% tong so bao cao ADR [4], co 111 ca t(( vong (chiem 82% so Iu'qng ca t(( vong nam cua toan bQcd so dG'Ii~u ADR), b~o cao lien quan den philn v~ chi chiem 0,9% tong so bao cao cd so dG' li~u bao cao ADR toan cau cua To ch((c Y te the gioi (Vigilyze) [5], Xuat phat tu thl/c te tren, nghien c((u du'qc thl/c hi~n nham tong ket d~c diem bao cao lien quan den philn ve cd so dG' li~u bao cao tl/ nguy~n Vi~t Na'm giai dOc;ln2010-2019 de h~ tr$1cong tac bao cao, x(( tri, dl/ phang va giilm thieu nguy co cua philn v~ 11.001TlIQNG VA PHlfO'NG PHAp NGHIENc(J'u D61tu'dng nghien cuu Tat cil cac bao cao tl/ nguy~j, ve philn ((ng co hc;licua thuoc (bao cao ADR) can bQ y te tren phc;lmvi cil nu'oc gU1ve Trung tam DI&ADR QUoc gia giai doan 2010-2019 'Du'a vao tieu chuan chan doan cac tru'ong hdp 'philn v~ du'qc quy dinh Thong tu' si/2017/TT-BYT [1], cac bao cao philn v~ du'qc du'a vao nghien c((u neu thea man dieu ki~n sau: - £)u'qc can bQy te me til la soc philn v~ ho~c philO ((ng philn v~ - ADRxuat hi~n yang tinh,tu Ian dung thu5c cu5i cung va co it nhat mQt bieu hi~n tren h~ cd quan da/niem mc;lc-hohaptieu hoa-tim mc;lchho~c co bieu hi~n hi;!huyet ap nghiem trQng 324 N°2 • NOVEMBER· 2020 Tieuchuanloai tnn Cac bao cao ADRthieu thong tin ve thucc 'nghi ngo va bieu hi~n ADR Phu'dng phap nghh1!ncuu Mo ta thong qua hoi cuu cac tru'ong hop phan v~ du'qc bao cao ve Trung tam DI&,ADRQuoc gia giai doan 2010-2019 voi cac chi tieu: So IWng, tY I~ bao cao phan v~ cd so dG'Ii~u theo nam: thong tin hanh chinh ghi nhan tu bao cao phan v~; D~c diem b~nh nhan ghi nhan bao cao phan v~; D~C diem cua thucc nghi ngo gay phan v~; D~c diem cua phan v~, cach xU' tri va ket qua sau xU'tri Nhom thuoc c~a cac hOc;ltchat nghi ngo gay phan v~ du'qc phan 10c;li dl/a tren cd so phan 10c;li rna ATC) Thai gian tiem tang xuat hi~n philn v~, bieu hi~n cua philn tren cac h~ cd quan (phan 10i;!itheo Hu'ong dan WHO - ADR Terminology 2012) [6], m((c dQ nghiem trQng cua cac tru'ong hdp philn v~ phan 10c;li theo Brown [3] va Hu'ong d§n QUocgia ve Cilnh giac Du'qc xU' Iy dU' Ii~u Toan bQ dG' Ii~u du'qc nh~p, xU' 1'1'tren phan mem Microsoft Office Excel 2016 va SPSS22.0 Cac bien du'qc thong ke theo tan suat va tY I~ phan tram tu 1~ III KET QuA NGHIEN CU'U Tu 73447 bao cao tl/ nguy~n Iu'utrG'ti;!i trung tam 01 & ADR Quoc gia giai dOc;ln2010-2019, sau 10i;li1971 bao cao, co 10027 bao cao philn v~ da du'qc du'a vao nghien c((u Sc) Iu'qng, tV I~ bao cao phim v~ thf!o nam 20 2500 18 16 ,,po 2000 > c 14 -III 'i "E 1500 12 10 -III u o 1000 -III ~ :!!' ?: 500 0 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 56 bao ,ao ph"n v~ _ TV I~ vOl t6ng so baD cao nghlen c(I'U(%) Hinh 1:So'lutlng va tY I~ bao caophan v~ theo tung nam So Iu'qng bao cao philO v~ tang aan qua cac nam tlt 155 bao cao (nam 2010) len 2235 bao cao nam 2019 (hinh 1) T'1 I~ bao cao philn v~ tren tong 55 bao cao ADR cua tung nam dao dQng khoilng 9,1%-17,3% quanh gia tri trung binh la 13,7% D~c diem cua ho~t dQng bao cao Ddn vi bao cao chu yeu thuQc khoi cong I~p (94,5%) Trung tâm DI&ADR Quốc gia - Tài liệu chia sẻ CANHGIACDUOC.ORG.VN facebook CANHGIACDUOC VIETNAM TAP CHi Y HOC VIET NAM TAp 496 - THANG 11 - Bang 1:S~c diem thong tin hanh chinh ghi nhan tv bao cao phan ve A • , , • A TYI~ Thong tin himh ehinh ghi Solu'qng (%) nh~n tit bao efto phim v~ ~c phim v~ (n = 10027' Oan vi bao e,ao Benh vien tuyen'Trung u'dng B~nh vi~n tuyen tinh/thanh Benh vien tuyen quan/huyen Benh vien tu' nhan Be'nh vien nganh Tru'ong f)ai hoc Y Du'dc 122 4493 44,8 3317 552 241 196 33,1 55 2,4 2,0 tuan - thanq > thang 329 414 19,2 3,0 35 3301 4153 1923 296 354 Thai gian bao eao 2631 < tuan 3688 3640 2 0,7 I 26,2 36,8 36,3 v~ Phim v~ du'