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Chapter 012 Drugs, Microbes, Host - The Elements of Chemotherapy Multiple Choice Questions Substances that are naturally produced by certain microorganisms that can inhibit or destroy other microorganisms are called A Antibioti cs B Narrow-spectrum drugs C Semi-synthetic drugs D Synthetic drugs E Broad-spectrum drugs Antimicrobials effective against a wide variety of microbial types are termed A Antibioti cs B Narrow-spectrum drugs C Semisynthetic drugs D Synthetic drugs E Broad-spectrum drugs Antibiotics are derived from all the following except A Penicilliu m B Bacillu s C Staphylococc us D Streptomyc es E Cephalosporiu m Important characteristics of antimicrobial drugs include A Low toxicity for human tissues B High toxicity against microbial cells C Do not cause serious side effects in humans D Stable and soluble in body tissues and fluids E All of the choices are correct Each of the following are true of antimicrobial therapeutic drugs except A Non-toxic to host B Easily broken down by host C Easily administered D Limited capacity to elicit resistance E Nonallergen ic The use of a drug to prevent imminent infection is called A Competitive inhibition B Synergis m C Prebiotic s D Prophylax is E Lantibioti cs The use of any chemical in the treatment, relief or prophylaxis of a disease is called A Prophylax is B Chemothera py C Selective toxicity D Nephrotoxici ty E Synergis m Pe nic illi ns an d ce ph al os po rin s A B C D E Se lec tiv e to xic ity ref er s to A B C D E 10 Ea ch of th e fol lo wi ng eff ec t cel l wa lls ex ce pt A B C D E :1 13 Id en tif yt wo ol de nd ne we nti mi cr ob ial st ta ct by in hi bit in g pr ot ei n sy nt he sis Le ar ni ng Ob je cti ve :1 13 Id en tif yt wo ol de nd tw o ne we nti mi cr ob ial st ta ct by in hi bit in g pr ot ei n sy nt he sis Le ar ni ng Ob je cti ve :1 14 Ex pl n ho w dr ug st ar ge tin gf oli c ac id sy nt he sis wo rk Le ar ni ng Ob je cti ve :1 15 Id en tif yt he ce llu lar tar ge to fq ui no lo ne s an d na m e ex a m pl es Le ar ni ng Ob je cti ve :1 16 Na m e dr ug st tt ar ge tt he ce llu lar m e m br an e Le ar ni ng Ob je cti ve :1 17 Di sc us s ho w tre at m en to fb io fl m inf ec tio ns di ffe rs th an th at of no nbi ofl m inf ec tio ns Le ar ni ng Ob je cti ve :1 18 Na m e m n ca te go rie s of an tif un ga la ge nt s an d pr ov id e on e ex a m pl e of ea ch Le ar ni ng Ob je cti ve :1 18 Na m et he m n ca te go rie s of an tif un ga la ge nt s an d pr ov id e on e ex a m pl e of ea ch Le ar ni ng Ob je cti ve :1 19 Na m e an tipr ot oz oa ld ru gs an d an tihe lm int hi c dr ug s Le ar ni ng Ob je cti ve :1 20 Lis tt he m aj or m od es of ac tio ns of an tivir al dr ug s Le ar ni ng Ob je cti ve :1 20 Lis tt he thr ee m aj or m od es of ac tio ns of an tivir al dr ug s Le ar ni ng Ob je cti ve :1 21 Di sc us s po ssi bl e wa ys th at mi cr ob es ac qu ire an ti mi cr ob ial re sis ta nc e Le ar ni ng Ob je cti ve :1 21 Di sc us st hr ee po ssi bl e wa ys th at mi cr ob es ac qu ire an ti mi cr ob ial re sis ta nc e Le ar ni ng Ob je cti ve :1 22 Lis t5 ce llu lar or str uc tu ral m ec nis m st t mi cr ob es us et or esi st an ti mi cr ob ial s Le ar ni ng Ob je cti ve :1 23 Di sc us s at le as t4 no ve la nti mi cr ob ial str at eg ies th at ar e un de ri nv es tig ati on Le ar ni ng Ob je cti ve :1 24 Di sti ng uis h be tw ee n dr ug to xic ity an d all er gi cr ea cti on st o dr ug s Le ar ni ng Ob je cti ve :1 25 Ex pl n w ta su pe rinf ec tio ni s an d ho wi to cc ur s Le ar ni ng Ob je cti ve :1 26 De sc rib e m et ho ds for te sti ng an ti mi cr ob ial su sc ep tib ilit y Le ar ni ng Ob je cti ve :1 27 De fn et he pe uti ci nd ex an di de nti fy w he th er a hi gh or al ow in de xi s pr ef er ab le Le ar ni ng Ob je cti ve :1 27 De fn et he pe uti ci nd ex an di de nti fy w he th er a hi gh or lo wi nd ex is pr ef er ab le Le ar ni ng Ob je cti ve :1 De fn e m et ab oli c an al og di sc us si ts rel ev an ce to an ti mi cr ob ial ac tio n Le ar ni ng Ob je cti ve :a nd id en tif y w hi ch mi cr ob es th ey ar e eff ec tiv e ag ns t Le ar ni ng Ob je cti ve :a nd w he re th ey ar ef ou nd Le ar ni ng Ou tc o m e: 12 Di sti ng uis h be tw ee n dr ug to xic ity an d all er gi cr ea cti on st o dr ug s ... t in hi bit D NA sy nt he sis ? A B C D E 16 Su lfo na mi de s A B C D E 17 Su lfa dr ug s wo rk on A B C D E 18 Su lfo na mi de s ar e an al og s of PA BA an d, as a re sul t, th... Important characteristics of antimicrobial drugs include A Low toxicity for human tissues B High toxicity against microbial cells C Do not cause serious side effects in humans D Stable and soluble... of any chemical in the treatment, relief or prophylaxis of a disease is called A Prophylax is B Chemothera py C Selective toxicity D Nephrotoxici ty E Synergis m Pe nic illi ns an d ce ph al