Stent MULTI LINK Phụ liệu PGS TS Võ Thành Nhân ĐH Y Dược – BV Chợ Rẫy TpHCM Only Bare Metal Stents Indicated for AMI Abbott Vascular continues the MULTI-LINK clinical heritage as the only company to offer BMS with FDA and CE AMI indication AMI Indicated 1995 MULTI-LINK Market Leader Now MULTI-LINK DUET Market Leader MULTI-LINK TRISTAR Market Leader MULTI-LINK TETRA Market Leader MULTI-LINK PENTA Market Leader MULTI-LINK ZETA Market Leader MULTI-LINK VISION Market Leader MULTI-LINK FDA and CE AMI indication for ML DUET, ML TRISTAR, ML TETRA, ML PENTA, ML ZETA, ML VISION MULTI-LINK stent CE marked and indicated for AMI MULTI-LINK is neither approved nor available for sale in the U.S Market leader claims based on market share data on file at Abbott Vascular as of September 2009 Images on file at Abbott Vascular ©2010 Abbott Vascular Confidential Internal use only Not to AP2931768-INTRev A (02/20) be reproduced, distributed, or excerpted Information contained ML8 APAC Train-the-Trainer Presentation herein for distribution outside the U.S and outside Japan Illustrations are artists’ renditions Not to be further reproduced, distributed or excerpted Internal use only For use in OUS geographies only Summary: Clinically Proven MULTI-LINK Design Built on generations of market-leading MULTI-LINK stents1 • Over million MULTI-LINK stents implanted2 Trusted Cobalt Chromium technology with 11 studies and over 11,000 patients • Built on the most clinically studied and widely used BMS, MULTI-LINK VISION Only bare metal stents indicated for AMI • Only company to offer BMS with FDA and CE AMI Indication3 Market leader claims based on market share data on file at Abbott Vascular as of September 2009 Includes MULTI-LINK, ML DUET, ML TRISTAR, ML TETRA, ML PENTA, ML ZETA, ML MINI VISION, ML VISION, XIENCE V and PROMUS Data on file at Abbott Vascular FDA and CE AMI indication for ML DUET, ML TRISTAR, ML TETRA, ML PENTA, ML ZETA, ML VISION MULTI-LINK stent CE marked and indicated for AMI MULTI-LINK is neither approved nor available for sale in the U.S Images on file at Abbott Vascular ©2010 Abbott Vascular Confidential Internal use only AP2931768-INTRev A (02/20) Not to be reproduced, distributed, or excerpted ML8 APAC Train-the-Trainer Presentation Information contained herein for distribution outside the U.S and outside Japan Illustrations are artists’ renditions Not to be further reproduced, distributed or excerpted Internal use only For use in OUS geographies only XIENCE PRIME CINE Dr Marquez VUMC, The Netherlands Case Description • SVG t-graft to OM • Lesion just proximal to anastomosis • Treatment: Place stent at lesion and anatomosis site and into distal portion of OM • Stent: 2.5 x 18 mm XIENCE PRIME Result • Excellent Conformability! • Restored distal flow and preserved proximal flow to OM AP2931768-INTRev A (02/20) ML8 APAC Train-the-Trainer Presentation ©2010 Abbott Vascular Confidential Internal use only Not to be reproduced, distributed, or excerpted Information contained herein for distribution outside the U.S and outside Japan Illustrations are artists’ renditions Not to be further reproduced, distributed or excerpted Internal use only For use in OUS geographies only EMEA Post Market Evaluation • 30 sites • 11 countries PME Success Stories Austria Customer Feedback • “Excellent deliverability” – France • “Stent goes in as butter” – Italy • “Compared to Driver, significantly better!” Poland In a patient with a lesion in the Mid LAD (3,0x12mm) and Prox LAD (3,5x23mm), Dr C Wolf decided to go for direct stenting to feel the "resistance" with MULTI-LINK But surprise, surprise there was nothing to feel He now wants MULTI-LINK consignment stock in his cath lab That's a big success because they kicked out Vision for Driver last year!! Poland Tartu University Hospital, Estonia ©2010 Abbott Vascular Confidential Internal use only Not to AP2931768-INTRev A (02/20) be reproduced, distributed, or excerpted Information contained ML8 APAC Train-the-Trainer Presentation herein for distribution outside the U.S and outside Japan Illustrations are artists’ renditions Dr Marcin Swierad treated three very challenging lesions (LM, OM, mid LAD) All the cases he compared to the Driver as significantly better !!! He said that he especially liked the pushability and short deflation time Not to be further reproduced, distributed or excerpted Internal use only For use in OUS geographies only Advanced MULTI-LINK Stent Design MULTI-LINK Enhancement for Deliverability MULTI-LINK Proximal End Ring Link Corrugated Ring Pattern Thin Struts Cobalt Chromium MULTI-LINK VISION Proven Features Taller NonLinear Link Longer Cell Length MULTI-LINK Enhancements MULTI-LINK MULTI-LINK VISION ©2010 Abbott Vascular Confidential Internal use only Not to be Not to be further reproduced, distributed reproduced, distributed, or excerpted Information contained AP2931768-INTRev A (02/20) or excerpted Internal use only For use herein for distribution outside the U.S and outside Japan ML8 APAC Train-the-Trainer Presentation in OUS geographies only Illustrations are artists’ renditions Advanced MULTI-LINK Stent Design MULTI-LINK Enhancement for Deliverability Taller Non-Linear Link for Flexibility and Conformability Taller non-linear link adds improved flexibility and conformability Body Ring Longer cell length = improved flexibility and better stent retention MULTI-LINK MULTI-LINK VISION ML VISION MULTI-LINK ©2010 Abbott Vascular Confidential Internal use only Not to Not to be further reproduced, distributed AP2931768-INTRev A (02/20) be reproduced, distributed, or excerpted Information or excerpted Internal use only For use ML8 APAC Train-the-Trainer Presentation contained herein for distribution outside the U.S and outside in OUS geographies only Japan Illustrations are artists’ renditions Advanced MULTI-LINK Stent Design MULTI-LINK VISION Proven Features Proven Features • 0.0032” thin struts for rapid reendothelialization • Trusted cobalt chromium stent alloy for biocompatibility, radial strength and radiopacity • 3-link, corrugated ring and link design for: • Conformability and flexibility • Uniform scaffolding • Reduced tissue prolapse • Strut apposition • Complete support on a bend Images on file at Abbott Vascular AP2931768-INTRev A (02/20) ML8 APAC Train-the-Trainer Presentation Not to be further reproduced, distributed ©2010 Abbott or excerpted Internal use only For use Vascular Confidential in OUS geographies only Internal use only Not to be reproduced, Corrugated Ring Design: Less Injury 32% Less injury with MULTI-LINK (corrugated ring) design 70% % Denuded Endothelium Palmaz-Schatz (slotted tube) MULTI-LINK (corrugated ring) 60% 50% 40% 30% 20% 63% 32% Reduction PalmazSchatz 43% (slotted tube) MULTI-LINK (corrugated ring) 10% 0% P