After studying this chapter you will be able to understand: The anatomy of a neuron; the mechanisms of impulse transmission in a neuron; the process that leads to release of neurotransmitters, and what happens at the synapse; how the vertebrate brain integrates information, which leads to an appropriate response; different regions of the brain have different functions.
Trang 11 Contrast the functions of B cells and T cells.
2 What are memory cells?3 How do vaccines work?
Trang 21 Draw and label the parts of a neuron.
2 Describe saltatory conduction.
Trang 31. What happens at the synapse?
2. Choose 1 neurotransmitter Describe its action.
3. What is the role of the following structures in the human brain?
a) Brainstem
b) Cerebellum
c) Cerebrum
Trang 4Chapters 48 & 49
Trang 5 The anatomy of a neuron.
The mechanisms of impulse transmission in a neuron.
The process that leads to release of neurotransmitters, and what happens at the synapse.
How the vertebrate brain integrates information, which leads to an
appropriate response.
Trang 6 Central nervous system (CNS) = brain + spinal cord
Peripheral nervous system (PNS) = nerves throughout body
Sensory receptors: collect info
Sensory neurons: body CNS
Motor neurons: CNS body (muscles, glands)
Interneurons: connect sensory & motor neurons
Nerves = bundles of neurons
Trang 13 cell body: contains nucleus & organelles
dendrites: receive incoming messages
axons: transmit messages away to other cells
myelin sheath: fatty insulation covering
axon, speeds up nerve impulses
synapse: junction between 2 neurons
neurotransmitter: chemical messengers
sent across synapse
Glia: cells that support neurons
Trang 18 Resting potential: membrane potential at rest; polarized
Na+ outside, K+ inside cell
Voltage-gated Na+ channel = CLOSED
Trang 25Chemicals released from vesicles by exocytosis into
synaptic cleft
Diffuse across synapse
Bind to receptors on neurons, muscle cells, or gland cells
Broken down by enzymes or taken back up into surrounding cells
Types of neurotransmitters:
Excitatory: speed up impulses by causing depolarization of postsynaptic membrane
Inhibitory: slow impulses by causing
Trang 27 Acetylcholine (ACh): stimulates muscles, memory formation, learning
Epinephrine: (adrenaline) fight-or-flight
Norepinephrine: fight-or-flight
Dopamine: reward, pleasure (“high”)
Loss of dopamine Parkinson’s Disease
Serotonin: well-being, happiness
Low levels Depression
GABA: inhibitory NT
Trang 30 Simple, automatic response to a stimulus
Trang 34• Forebrain cerebrum• Midbrain brainstem
• Hindbrain
Trang 35StructureFunction
Cerebrum
•Information processing (learning, emotion, memory, perception,
voluntary movement)
•Right & Left cerebral hemispheres•Corpus callosum: connect
hemispheres
Brainstem
*Oldest evolutionary part*
•Basic, autonomic survival behaviors
•Medulla oblongata –breathing, heart
& blood vessel activity, digestion, swallowing, vomiting
•Transfer info between PNS & CNS
Cerebellum
Trang 36StructureFunction
Cerebrum
•Information processing (learning, emotion, memory, perception,
voluntary movement)
•Right & Left cerebral hemispheres
•Corpus callosum: connect
hemispheres
Brainstem
*Oldest evolutionary part*
•Basic, autonomic survival behaviors
•Medulla oblongata –breathing, heart
& blood vessel activity, digestion, swallowing, vomiting
•Transfer info between PNS & CNS
Cerebellum
•Coordinate movement & balance•Motor skill learning
Trang 37StructureFunction
Cerebrum
•Information processing (learning, emotion, memory, perception,
voluntary movement)
•Right & Left cerebral hemispheres
•Corpus callosum: connect
hemispheres
Brainstem
*Oldest evolutionary part*
•Basic, autonomic survival behaviors
•Medulla oblongata –breathing, heart
& blood vessel activity, digestion, swallowing, vomiting
•Transfer info between PNS & CNS
Cerebellum
•Coordinate movement & balance•Motor skill learning
Trang 38StructureFunction
Cerebrum
•Information processing (learning, emotion, memory, perception,
voluntary movement)
•Right & Left cerebral hemispheres
•Corpus callosum: connect
hemispheres
Brainstem
*Oldest evolutionary part*
•Basic, autonomic survival behaviors
•Medulla oblongata –breathing, heart
& blood vessel activity, digestion, swallowing, vomiting
•Transfer info between PNS & CNS
Cerebellum
•Coordinate movement & balance•Motor skill learning