CHUI Hễ HP T BO 1) Nng lng gii phúng t cỏc liờn kt giu nng lng l: a) 6,6 cal/mol b) 6,6 Kcal/mol c) 66 cal/mol d) C cõu trờn u sai 2) Vai trũ s phosphoryl húa v kh phosphoryl l: a) Tớch tr, chuyn v s dng nng lng b) Hot húa cỏc cht c) Hot húa cỏc cht enzym d) C cõu trờn u ỳng 3) Trong chui hụ hp t bo ATP c to v trớ quỏ trỡnh chuyn hydro v in t t NADH,H+ ti oxy l: a) NAD-FAD; Cytb-Cytc; Cyta3 1/2O2 b) SH2-NAD; Cytb-Cytc; Cyta3 1/2O2 c) NAD-FAD; CoQ-Cytb; Cyta3 1/2O2 d) FAD-CoQ; Cytb-Cytc; Cyta3 1/2O2 a) b) c) d) 4) Vai trũ ca chu trỡnh Krebs l: Oxy húa pyruvate t s phõn gii glucose thnh CO2 v H2O Oxy húa acetyl CoA t s phõn gii cỏc acid bộo Cung cp cỏc tin cht cho quỏ trỡnh sinh tng hp C cõu trờn u ỳng HểA HC CHUYN HểA PROTID H3C CH COOH CH2 H3C NH2 5) OH H2C laứ coõng thửực cuỷa : COOH CH2 NH2 6) H3C S H2C laứ coõng thửực cuỷa : H2C NH2 7) NH2 (CH2)3 H C CH2 laứ coõng thửực cuỷa : COOH NH2 8) H2 C CH laứ coõng thửực cuỷa : COOH NH2 9) H2 C HN H C laứ coõng thửực cuỷa COOH NH2 NH laứ coõng thửực cuỷa : 10) HN 11) COOH CH NH H C H C OH NH2 COOH laứ coõng thửực cuỷa HOOC 12) H C H C OH NH2 COOH laứ coõng thửực cuỷa H3C CH H C H C OH NH2 COOH H3C 13) laứ coõng thửực cuỷa 14) 5-oxy Lysin l : a- acid amin khụng gp phõn t protein b- acid amin him gp phõn t protein c- acid amin thng gp phõn t protein d- acid imin 15) 4-hydroxy Prolin l : a- acid amin khụng gp phõn t protein b- acid amin him gp phõn t protein c- acid amin thng gp phõn t protein d- a, b, c u sai 16) Cỏc acid amin sau cú ng phõn lp th : a- Threonin v Isoleucin b- Threonin v Leucin c- Leucin v Isoleucin d- a, b, c u sai 17) Tyrosin, Tryptophan v Phenylalanin hp thu mnh vựng bc súng no ? 18) Nhng acid amin no cụng thc cú cha lu hunh? 19) Tp hp acid amin no vi gc R cú cha nhúm OH 20) Tp hp acid amin no sau õy vi gc R chui hydrocarbon no 21) Phn ng Edman (Phenylisothiocyanat) c s dng : 22) Phn ng Sanger (2,4 dinitrofluorobenzen) c s dng : 23) Phn ng gia acid amin v formaldehyd c Sorensen ng dg 24) Phn ng Ninhydrin dựng : 25) Liờn kt disulfur l : 26) Phn ng Biuret dựng : 27) Peptid : a- l nhng protid gm t n vi chc acid amin ni vi bi cỏc liờn kt peptid b- cú cỏc pHi riờng bit cho tng cht c- cho phn ng vi thuc th Milon d- a, b, c u ỳng 28) Glutathion l mt peptid gm acid amin : 29) c im ca peptide hormone Insulin 30) c im Casein ca sa? 31) protein n gin? 32) Mt protein c gi l bin tớnh no? 33) Carboxypeptidase khụng hot ng nu acid amin tn cựng l? 34) Quỏ trỡnh hp thu ca cỏc L- acid amin qua thnh rut : 35) Quỏ trỡnh kh amin ca acid amin c th ng vt bao gi cng l : 36) Trong chu trỡnh urờ phn ng to carbamyl phosphat xy : 37) Trong chu trỡnh urờ, acid aspartic gi vai trũ: 38) S tng hp glutamin c th cn : 39) chim v loi bũ sỏt: a NH3 c tng hp thnh acid uric v o thi b NH3 c o thi trc tip vo mụi trng c NH3 c tng hp ure ri o thi d NH3 c dựng tng hp cỏc mui NH4+ o thi 40) Pepsin c hiu vi nhng liờn kt peptid? 41) Trong chu trỡnh urờ, arginin c thy phõn di tỏc dng ca arginase thnh: 42) Tp hp cỏc acid amin no l cỏc acid amin cn thit 43) Tp hp cỏc acid amin no l cỏc acid amin trung tớnh 44) Tp hp cỏc acid amin no l cỏc acid amin acid 45) Tp hp cỏc acid amin no l cỏc acid amin kim 46) Tp hp cỏc acid amin no l cỏc acid amin mch vũng 47) Tp hp cỏc acid amin no l cỏc acid amin cú gc R phõn cc 48) Tp hp cỏc acid amin no l cỏc acid amin cú gc R phõn cc 49) Chn phỏt biu ỳng nht a Diiodo tyrosin l dn xut ca tyrosin b Diiodo tyrosin l acid him gp phõn t protein c Diiodo tyrosin cú globulin ca tuyn giỏp d a, b v c u ỳng 50) Cỏc acid amin cu to ca phõn t protein u cu dng 51) Cỏc acid amin u cú ph hp thu vựng 52) mụi trng cú pH= 3,9 cỏc acid amin s tớch in nh sau a acid aspartic cú pHi= 2,77 s tớch in dng b acid glutamic cú pHi= 3,12 s tớch in dng c alanin cú pHi= 6,02 s tớch in õm d a, b,c u sai 53) mụi trng cú pH= 6,8 cỏc acid amin s tớch in nh sau a cỏc acid amin cú pHi nh hn 6,8 s tớch in õm b cỏc acid amin cú pHi ln hn 6,8 s tớch in dng c a v b u ỳng d a v b u sai 54) mụi trng cú pH= pHi thỡ acid amin s nh th no? 55) Phn ng gia aldehyd v acid amin xy trờn nhúm chc 56) Phn ng gia HNO2 v acid amin xy trờn nhúm chc 57) Phn ng gia thuc th ninhydrin v acid amin xy trờn nhúm chc 58) Pepsin thy phõn cỏc liờn kt peptid? 59) Trypsin thy phõn cỏc liờn kt peptid? 60) Chymotrypsin thy phõn cỏc liờn kt peptid? 61) Aminopeptidase thy phõn liờn kt peptid? 62) Carboxypeptidase thy phõn liờn kt peptid? 63) Cỏc catepsin c cha bo quan no? 64) Phn ỳng kh amin-oxy húa cỏc acid amin chu s xỳc tỏc ca 65) Coenzym ca cỏc transaminase l 66) Hai loi transaminase hot ng mnh v ph bin c th l 67) Trong trng hp viờm gan cp tớnh vi rut thỡ a GOT tng nhiu hn GPT b GPT tng nhiu hn GOT c C hai GOT v GPT u tng cao d a,b, c u sai 68) Trong trng hp nhụi mỏu c tim thi a GOT tng nhiu hn GPT b GPT tng nhiu hn GOT c C hai GOT v GPT u tng cao d a,b, c u sai 69) Chn phỏt biu ỳng a Phn ln cỏc acid amin u c kh amin- oxy húa giỏn tip qua cỏc transaminase cựng vi a -cetoglutaric vaứ glutamat dehydrogenase b Phn ln cỏc acid amin u c kh amin- oxy húa trc tip qua cỏc transaminase c Phn ln cỏc acid amin u c kh amin- oxy húa trc tip qua cỏc dehydrogenase d a,b c u sai 70) GABA cú tỏc ng 71) c im ca Glutamin 72) S to thnh Carbamyl phosphat chu trỡnh ure xy 73) Ornitin carbamyl tranferase xỳc tỏc phn ng 74) Arginosuccinat synthetase xỳc tỏc phn ng 75) Arginosuccinat lyase xỳc tỏc phn ng chuyn arginosuccinat thnh 76) Arginase xỳc tỏc phn ng thy phõn arginin thnh 77) Trong chu trỡnh urờ tng hp mt phõn t urờ cn 78) Giai on v ca chu trỡnh urờ xy 79) a b c d 80) a b c d Cỏc bnh v gan lm tng nng urờ mỏu gim nng urờ mỏu khụng thay i nng urờ mỏu tng nng urờ nc tiu Viờm thn lm tng nng urờ mỏu gim nng urờ mỏu khụng thay i nng urờ mỏu tng nng urờ nc tiu 81) Tp hp cỏc acid amin no l cỏc acid amin cn thit 82) c im Arginin ? 83) Acid amin khụng cn thit ?