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DEPRESSIVE SYMPTOMS AND RELATED FACTORS OF THE GENERAL MEDICAL STUDENT AT HAI PHONG UNIVERSITY OF MEDICINE AND PHARMACY IN 2016

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`MINISTRY OF HEALTH MINISTRY OF EDUCATION AND TRAINING HAI PHONG UNIERSITY OF MEDICINE AND PHARMACY NGUYEN THI MO DEPRESSIVE SYMPTOMS AND RELATED FACTORS OF THE GENERAL MEDICAL STUDENT AT HAI PHONG UNIVERSITY OF MEDICINE AND PHARMACY IN 2016 GRADUATE THESIS OF PREVENTIVE MEDICINE DOCTOR HAI PHONG 6/2016 `MINISTRY OF HEALTH MINISTRY OF EDUCATION AND TRAINING HAI PHONG UNIERSITY OF MEDICINE AND PHARMACY NGUYEN THI MO DEPRESSIVE SYMPTOMS AND RELATED FACTORS OF THE GENERAL MEDICAL STUDENT AT HAI PHONG UNIVERSITY OF MEDICINE AND PHARMACY IN 2016 Majors: Preventive Medicine Doctor Code : GRADUATE THESIS OF PREVENTIVE MEDICINE DORTOR Thesis Advisors: Master Nguyen Thi Minh Ngoc Master Nguyen Thi Thu Thao HAI PHONG 6/2016 DECLARATION I am sure that this graduate thesis is my own study; all investigated data and researching results which are actually honest and logical, have never been published in other research projects NGUYEN THI MO ACKNOWLEDGMENT I would like to express my sincere gratitude: The Rector Board and Department of Undergraduate Education, Hai Phong University of Medicine and Pharmacy The Chairmen Board and lecturers of the Department of Public Health at Hai Phong University of Medicine and Pharmacy dedicatedly instructed me to study and complete my thesis Meanwhile, the training University department assists me to collect accurate and reliable data particularly I would like to express my faithful thanks to Master Nguyen Thi Minh Ngoc and Nguyen Thi Thu Thao, who spent a lot of their time on instructing me for my thesis I sincerely thank Mr Ha Van Truong, the lecturer at the Ha Truong English center guided, instructed and prompted me in English language My family and friends always encourage and support me to study and complete my thesis Hai Phong, 25/5/2016 Author Nguyen Thi Mo ABBREVIATIONS CES-D C.I WHO The center for epidemiologic studies depression scale Confidence interval The World Health Organization CONTENT INTRODUCTION .1 CHAPTER .3 Literature review .3 1.1 Concepts of depression .3 1.3 Risk factors and consequences of depression in medical students 11 1.4 Depression measurement 14 CHAPTER .17 METHODOLOGY .17 2.1 Study subjects 17 2.2 Study location 17 2.3 Study time 17 2.4 Methodology .17 2.5 Data processing and analysis 21 2.6 Ethical study .22 CHAPTER .23 RESULT 23 3.1 Description of general characteristics 23 3.2 Students have depressive symptoms based on the CES-D scale 26 3.3 Depressive symptoms and related factors 29 DISCUSSION 38 4.1 The general characteristics and depressive symptom of the study subjects 38 4.2 Related factors to depressive symptoms of general medical students at Hai Phong University of Medicine and Pharmacy, 2015 – 2016 .42 CONCLUSION 53 RECOMMENDATION 55 REFERENCES QUESTIONNAIRE Part C: Stressful life events 10 LIST OF TABLE Table 2.1: Distribution of the sample size in grade Table 2.2: Variables and index measurement Table 3.1: Distribution of subject by religion and year in course Table 3.2: Distribution of subject by parents’ education Table 3.3: Distribution of subject by current residence Table 3.4: Positive signs according to the CES-D Table 3.5: Difficulty in communication signs based on the CES-D Table 3.6: Depressed signs based on the CES-D Table 3.7: Active selves signs according to the CES-D Table 3.8: The relationship between depressive symptom and grade Table 3.9: The relationship between depressive symptom and gender Table 3.10: The relationship between depressive symptom and religion Table 3.11: The relationship between depressive symptom and current 19 20 25 27 28 29 29 30 31 33 34 34 35 residence Table 3.12: The relationship between depressive symptom and parents’ 36 marital status Table 3.13: The relationship between depressive symptom and family 38 residence Table 3.14: The relationship between friends, society and depressive 38 symptom Table 3.15: The relationship between the family factors and depressive 40 symptom Table 3.16: The relationship between depressive symptom and 41 interpersonal sources Table 3.17: The relationship between the study- related factors and 42 depressive symptom LIST OF FIGURES Figure 1.1: Proposed model of causes and consequences of student 15 distress Figure 3.1: Distribution of subject by gender Figure 3.2: Distribution of subject by ethnicity and course Figure 3.3: Distribution of subject by family residence Figure 3.4: Percentage of depressive symptom among the students 25 26 27 32 INTRODUCTION Depression is now becoming one of the most serious mental health issues and social problems in many countries and trending to increase in the next 20 years [31] Depressive symptoms are widely distributed in the population and disrupt people’s normal life According to World Health Organization (2012), depression is a significant contributor to the global burden of disease with an estimated 350 million people in all communities across the world affected [37] Moreover, every year, approximately 5% of the world population have depression [36] WHO predicts that by 2020 depression will be the second cause of loss of working second in the world [37] Depression results from a complex interaction of social psychological and biological factors Especially, when long-lasting and with moderate or severe intensity, depression can lead to lead to more stress and dysfunction, worsen the affected person’s life situation At its worst, depression can lead to suicide Within about million cases die per year in the world, the suicide is the second leading cause of death in the 15-29 age-group [37] However, in Vietnam, a scientific awareness about depression is still limited "Feeling sad" has been seen as a normal shape of mood, not to be considered as criteria for evaluating early signs of depression The early evaluation of depressive signs is an extremely important thing to prevent the occurrence as well as to have effective treatment process for depression So far there have been few types of research on depressive symptoms in Vietnamese people as well as students, especially on medical students Students have to experience numerous challenges including exploring or developing their identity, navigating the transition from a state of 55 RECOMMENDATION According to the obtained research results, we propose a number of recommendations designed in order to limit the depressive symptom in students at the university as followings: - A range of discussion activities on experience and scientific learning methods to help student avoid stress and fatigue should be increasingly held throughout joining to studying club such as English clubs, French clubs , participating in extracurricular activities such as sports, dance sports club, guitar club Besides, chatting with friends and relatives is required for keeping psychological state balanced in stressful learning process - The extracurricular activities, psychological seminar are of necessity for the guidance on preventing depression from students, especially for freshmen enrolling at the university - Psychological counseling room in the school is critical to help students have difficulties in learn and in their personal life - In order to detect early depressive symptom in the student, it is necessary to carry on regular psychological tests - More research on each student form specialized in the particular problems should be taken place to find out solution of students' depression REFERENCES Vietnamese Nguyễn Thị Thiên Ân (2009), Biểu bệnh trầm cảm bệnh nhân độ tuổi từ 18-45 điều trị Bệnh viện tâm thần Đà Nẵng từ tháng 10/08-3/09, Khoá luận tốt nghiệp ngành Tâm lý học, Đại học sư phạm - Đại học Đà Nẵng Bộ Y tế, Đại học Y Dược Hải Phịng (2014), Thơng báo tuyển sinh đại học, http://hpmu.edu.vn/hpmu/news/Dai-Hoc-32/Thong-bao-tuyen-sinh-Daihoc-421/, truy cập ngày 24/5/2015 Bộ Y tế, Tổng cục thống kê, UNICEF, WHO (2009), “Điều tra quốc gia Vị thành niên niên Việt Nam Lần thứ 2” Nguyễn Thanh Cao (2011), Thực trạng trầm cảm số yếu tố nguy đến trầm cảm người trưởng thành phường sông Cần,thị xã Bắc Kan năm 2011 đề xuất số giải pháp, Luận án chuyên khoa cấp II chuyên ngành Y tế công cộng, Đại học Y Dược Thái Nguyên Nguyễn Thanh Hương, Lê Vũ Anh, Michael Dunne (2007), “Giá trị độ tin cậy hai thang trầm cảm lo âu sử dụng nghiên cứu cộng đồng với đối tượng vị thành niên” Tạp chí Y tế cơng cộng, 25 (7), tr 25-31 Nguyễn Thị Bích Liên (2011), Nguy trầm cảm số khối sinh viên đa khoa trường Đại học Y Hà Nội năm 2010 -2011 số yếu tố liên quan, Khoá luận tốt nghiệp, Đại học Y Hà Nội Nguyễn Văn Siêm (2010), Nghiên cứu dịch tễ học lâm sàng rối loạn trầm cảm xã đồng sông Hồng, Báo cáo y học, Bệnh viện tâm thần trung ương Trần Bình Thắng, Võ Văn Thắng, Micheal P Dunne, Trần Quỳnh Anh (2013), “Trầm cảm, ý định tự sát lo âu sinh viên y khoa miền trung Việt Nam: tỷ lệ yếu tố liên quan”, Tạp chí Y học thực hành, (880), tr 216-20 Nguyễn Viết Thiêm (1993), Đặc điểm trạng thái trầm cảm lâm sàng tâm thần học ngày nay, Các chuyên đề tâm thần học, Hà Nội, tr 63-70 10 Nguyễn Minh Tuấn (2002), “Các rối loạn tâm thần chẩn đoán điều trị”, Nhà xuất Y học, Hà Nội, tr 78-87 11 Báo điện tử (2015), Báo động sinh viên Y khoa bị trầm cảm, có ý nghĩ tự tử gia tăng, http://dantri.com.vn/suc-khoe/bao-dong-sinh-vien-y-khoa-bitram-cam-co-y-nghi-tu-tu-gia-tang-1421703618.htm, truy cập ngày 24/11/2015 English 12 Ahmed K.Ibrahim, Shona J Kelly, Clive E Adams (2013), “A systematic review of students of depression prevalence in university students”, Journal of psychiatric research, 47 (3), pp 391-400 13 Baldassin S, et al (2008), “The characteristics of depressive symptoms in medical students during medical education and training: a cross-sectional study”, BMC Med Educ, 8, pp 60 14 Caleb J Othieno (2014), “Depression among university students in Kenya: prevalence and sociodemographic correlated”, Journal of affective disorders, 165, pp 120-125 15 Deboral Goebert, et al (2009), “Depressive symptoms in Medical students and residents: A multischool study”, Academic Medicine, Vol 84, No 16 Dr Michelle Fuck (2005), “Child and adolescent mental health policies and plans”, Mental Health Policy and Service Guidance Package, World Health Organization, Geneva 17 Dr Sudhir Khandelwal, Dr AKMN Chowdhury (2011), “Conquering depression”, Regional Office for South East Asia, World Health Organization, Geneva 18 Dyerbye, R.Thomas, D Shanafelt (2005), “Medical student distress: causes, consequences, and proposed solutions”, Mayo Clinic Proceedings, 80 (12), pp 1613-1622 19 Field, Diego, Sander (2001), “Adolescent depression and risk factors”, Adolescence, 36 (143), pp 491-498 20 Giuseppe Grosso, Andrzej Pajak (2014), “Role of omega-3 Fatty Acids in The Treatment of Depressive disorders: A Comprehensive Meta- Analysis of Radomized Clinical Trials”, PLOS ONE, (5) 21 Hamza Mohammad Abdulghani (2008), “Stress and depression among medical students, A cross sectional study at a medical college in Saudi Arabia, Pakistan”, Pakistan Journal of medical sciences, 24 (1), pp 12-17 22 Iqbal S, Gupta S, Venkatarao E (2015), “Stress, anxiety & depression among medical undergraduate students & their socio-demographic correlates”, Indian J Med Res, 141 (3), pp 354- 357 23 Jadoon NA et al (2010), “Anxiety and depression among medical students: a cross-sectional study”, Journal of Pakistan Medical Association, 60 (8), pp 699-702 24 Jafari N, A Loghmani A and A Montazeri (2012), “Mental health of Medical students in different levels of training”, Int J Prev Med, (Suppl 1), pp 107-12 25 Kwaku oppong Asante (2015), “Prevalence and determinants of depression symptoms among university students in Ghana”, Journal of affective disorders, 171, pp 161-166 26 Luchen, Lin Wang, Xiao Hui Qui (2013), “Depression among Chinese University students: prevalence and Socio – Demographic Correlates”, PLOS ONE, (3) 27 Mae Lynn Reyes- Rodriguez (2013), “Depression symptoms and stressful life events among college students in Puerto Rico”, Journal of Affective disorders, 145, pp 324-333 28 McDowell (2006), “Measurering Health”, A guide to rating scales and questionnaires (3nd), New York: Oxford University press 29 Motaz B Ibrahim, Moataz H Abdecreheem (2015), “Prevalence of anxiety and depression among medical and pharmacy students in Alexandria University”, Alexandria Journal of medicine, 51, pp 167-173 30 Niemi PM, Vainiomaki PT (2006), “Medical students' distress-quality, continuity and gender differences during a six-year medical programme”, Med Teach, 28 (2), pp 136-41 31 Quyen D.D (2007), Depression and stress among the first year medical students in university of medicine and pharmacy Hochiminh city, Viet Nam, College of Public Heath Sciences, Chulalongkorn University 32 Radoloff, L.S (1977), “The CES-D scale: A self - report depression scale for research in the general population”, Applied Psychological measurement, (3), pp 385-401 33 Saipanish, R (2003), “Stress among medical students in a Thai medical school”, Med Teach, 25 (5), pp 502-506 34 Somrongthong (2004), Adolescent health needs, Accessibility of services, Depression and Quality of Life by assisting in the development of community partnerships, Doctoral dissertation, College of Public Health, Chulalongkorn University 35 Anh Tran Quynh, Michael P Dunne (2014), “Well- being, depression and suicidal ideation among medical students throughout Viet Nam”, Journal of medicine and pharmacy, (3), pp 23-30 36 World Health Organization (2012), “Depression”, Media centre, Geneva 37 World Health Organization (2012), “Fact sheet 369 – Depression”, Media centre, Geneva 38 Yuqing, Yueqin, H.Liu, D Kwan (2008), Depression in college: depressive symptoms and personality factors in Beijing and Hong Kong college freshmen, Comprehensive Psychiatry 39 Yusoff MS, Abdul Rahim AF, Baba AA et al (2013), “Prevalence and associated factors of stress, anxiety and depression among prospective medical students”, Asian Journal of Psychiatry, (2), pp 128-33 QUESTIONNAIRE Dear students, being a student in 6th form, we conduct a study to measure prevalence of depressive symptom and related factors in the learning environment Your information will be managed confidentially, only for research purpose and contributed to improve quality of the academic environment and your well-being as well Fill this box □ with your suitable choice Part A: you and yours’ family A1 A2 A3 A4 A5 A6 Gender Birth year Ages Ethnic Religion Year in course Male Ages Kinh Nung Tay Dao Hoa H’Mong Kmer Other Non-religion Christian Buddhist Other Freshman Fourth form Second form Fifth form Third form Rural area Sixth form A7 A8 A9 Family’s residence Current residence Parents’ marital status Female Urban area Dormitory Room/house rent Living with parents/ relation Other Live together Separated Divorce Parental loss Always A10 Often How often you excises? Sometime Seldom A11 Grade point average Never < 5,5 5,5-6,4 6,5-7,4 7,5-8,4

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12. Ahmed K.Ibrahim, Shona J. Kelly, Clive E. Adams (2013), “A systematic review of students of depression prevalence in university students”, Journal of psychiatric research, 47 (3), pp. 391-400 Sách, tạp chí
Tiêu đề: A systematic review of students of depression prevalence in university students”, "Journal of psychiatric research
Tác giả: Ahmed K.Ibrahim, Shona J. Kelly, Clive E. Adams
Năm: 2013
13. Baldassin S, et al (2008), “The characteristics of depressive symptoms in medical students during medical education and training: a cross-sectional study”, BMC Med Educ, 8, pp. 60 Sách, tạp chí
Tiêu đề: The characteristics of depressive symptoms in medical students during medical education and training: a cross-sectional study”, "BMC Med Educ
Tác giả: Baldassin S, et al
Năm: 2008
14. Caleb J. Othieno (2014), “Depression among university students in Kenya: prevalence and sociodemographic correlated”, Journal of affective disorders, 165, pp. 120-125 Sách, tạp chí
Tiêu đề: Depression among university students in Kenya: prevalence and sociodemographic correlated”, "Journal of affective disorders
Tác giả: Caleb J. Othieno
Năm: 2014
15. Deboral Goebert, et al (2009), “Depressive symptoms in Medical students and residents: A multischool study”, Academic Medicine, Vol 84, No 2 Sách, tạp chí
Tiêu đề: Depressive symptoms in Medical students and residents: A multischool study”, "Academic Medicine
Tác giả: Deboral Goebert, et al
Năm: 2009
16. Dr Michelle Fuck (2005), “Child and adolescent mental health policies and plans”, Mental Health Policy and Service Guidance Package, World Health Organization, Geneva Sách, tạp chí
Tiêu đề: Child and adolescent mental health policies and plans”, "Mental Health Policy and Service Guidance Package
Tác giả: Dr Michelle Fuck
Năm: 2005
17. Dr Sudhir Khandelwal, Dr AKMN Chowdhury (2011), “Conquering depression”, Regional Office for South East Asia, World Health Organization, Geneva Sách, tạp chí
Tiêu đề: Conquering depression”, "Regional Office for South East Asia
Tác giả: Dr Sudhir Khandelwal, Dr AKMN Chowdhury
Năm: 2011
18. Dyerbye, R.Thomas, D. Shanafelt (2005), “Medical student distress: causes, consequences, and proposed solutions”, Mayo Clinic Proceedings, 80 (12), pp. 1613-1622 Sách, tạp chí
Tiêu đề: Medical student distress: causes, consequences, and proposed solutions”, "Mayo Clinic Proceedings
Tác giả: Dyerbye, R.Thomas, D. Shanafelt
Năm: 2005
19. Field, Diego, Sander (2001), “Adolescent depression and risk factors”, Adolescence, 36 (143), pp. 491-498 Sách, tạp chí
Tiêu đề: Adolescent depression and risk factors”, "Adolescence
Tác giả: Field, Diego, Sander
Năm: 2001
20. Giuseppe Grosso, Andrzej Pajak (2014), “Role of omega-3 Fatty Acids in The Treatment of Depressive disorders: A Comprehensive Meta- Analysis of Radomized Clinical Trials”, PLOS ONE, 9 (5) Sách, tạp chí
Tiêu đề: Role of omega-3 Fatty Acids in The Treatment of Depressive disorders: A Comprehensive Meta- Analysis of Radomized Clinical Trials”, "PLOS ONE
Tác giả: Giuseppe Grosso, Andrzej Pajak
Năm: 2014
22. Iqbal S, Gupta S, Venkatarao E (2015), “Stress, anxiety &amp; depression among medical undergraduate students &amp; their socio-demographic correlates”, Indian J Med Res, 141 (3), pp. 354- 357 Sách, tạp chí
Tiêu đề: Stress, anxiety & depression among medical undergraduate students & their socio-demographic correlates”, "Indian J Med Res
Tác giả: Iqbal S, Gupta S, Venkatarao E
Năm: 2015
23. Jadoon NA et al (2010), “Anxiety and depression among medical students: a cross-sectional study”, Journal of Pakistan Medical Association, 60 (8), pp. 699-702 Sách, tạp chí
Tiêu đề: Anxiety and depression among medical students: a cross-sectional study”, "Journal of Pakistan Medical Association
Tác giả: Jadoon NA et al
Năm: 2010
24. Jafari N, A Loghmani A and A Montazeri (2012), “Mental health of Medical students in different levels of training”, Int J Prev Med, 3 (Suppl 1), pp. 107-12 Sách, tạp chí
Tiêu đề: Mental health of Medical students in different levels of training”, "Int J Prev Med
Tác giả: Jafari N, A Loghmani A and A Montazeri
Năm: 2012
25. Kwaku oppong Asante (2015), “Prevalence and determinants of depression symptoms among university students in Ghana”, Journal of affective disorders, 171, pp. 161-166 Sách, tạp chí
Tiêu đề: Prevalence and determinants of depression symptoms among university students in Ghana”, "Journal of affective disorders
Tác giả: Kwaku oppong Asante
Năm: 2015
26. Luchen, Lin Wang, Xiao Hui Qui (2013), “Depression among Chinese University students: prevalence and Socio – Demographic Correlates”, PLOS ONE, 8 (3) Sách, tạp chí
Tiêu đề: Depression among Chinese University students: prevalence and Socio – Demographic Correlates”, "PLOS ONE
Tác giả: Luchen, Lin Wang, Xiao Hui Qui
Năm: 2013
27. Mae Lynn Reyes- Rodriguez (2013), “Depression symptoms and stressful life events among college students in Puerto Rico”, Journal of Affective disorders, 145, pp. 324-333 Sách, tạp chí
Tiêu đề: Depression symptoms and stressful life events among college students in Puerto Rico”, "Journal of Affective disorders
Tác giả: Mae Lynn Reyes- Rodriguez
Năm: 2013
28. McDowell (2006), “Measurering Health”, A guide to rating scales and questionnaires (3nd), New York: Oxford University press Sách, tạp chí
Tiêu đề: Measurering Health”, "A guide to rating scales and questionnaires
Tác giả: McDowell
Năm: 2006
29. Motaz B. Ibrahim, Moataz H. Abdecreheem (2015), “Prevalence of anxiety and depression among medical and pharmacy students in Alexandria University”, Alexandria Journal of medicine, 51, pp. 167-173 Sách, tạp chí
Tiêu đề: Prevalence of anxiety and depression among medical and pharmacy students in Alexandria University”, "Alexandria Journal of medicine
Tác giả: Motaz B. Ibrahim, Moataz H. Abdecreheem
Năm: 2015
30. Niemi PM, Vainiomaki PT (2006), “Medical students' distress-quality, continuity and gender differences during a six-year medical programme”, Med Teach, 28 (2), pp. 136-41 Sách, tạp chí
Tiêu đề: Medical students' distress-quality, continuity and gender differences during a six-year medical programme”, Med "Teach
Tác giả: Niemi PM, Vainiomaki PT
Năm: 2006
33. Saipanish, R. (2003), “Stress among medical students in a Thai medical school”, Med Teach, 25 (5), pp. 502-506 Sách, tạp chí
Tiêu đề: Stress among medical students in a Thai medical school
Tác giả: Saipanish, R
Năm: 2003
34. Somrongthong (2004), Adolescent health needs, Accessibility of services, Depression and Quality of Life by assisting in the development of community partnerships, Doctoral dissertation, College of Public Health, Chulalongkorn University Sách, tạp chí
Tiêu đề: Adolescent health needs, Accessibility of services, Depression and Quality of Life by assisting in the development of community partnerships
Tác giả: Somrongthong
Năm: 2004

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