Nghiên cứu lâm sàng ABSORB và một vài ca tại bệnh viện chợ rẫy

Chương trình nghiên cứu ABSORB và ca lâm sàng tại Bệnh Viện Chợ Rẫy PGS TS Võ Thành Nhân ĐH Y Dược – BV Chợ Rẫy TP HCM Các bước ngoặc trong lịch sử TMH can thiệp 1977 Balloon Angioplasty (PTCA) Bare Metal Stents (BMS) Coronary Drug Eluting Stents (DES) Absorb Bioresorbable Vascular Scaffold (BVS) 1977 1988 2001 Today After implant. After resorption. Gruentzig J Puel MC Morice Absorb là phương thức điều trị mới, tác dụng qua 3 giai đoạn Hệ thống giá đỡ tự tiêu Absorb [...]... mạch ở 1 số bệnh nhân) ABSORB EXTEND Có thể đến 1000 bệnh nhân tại 100 trung tâm trên toàn thế giới Mục tiêu nghiên cứu: tiếp tục thử nghiệm lâm sàng rộng hơn Tiêu chí đánh giá: tiêu chí lâm sàng kinh điển của PCI Sang thương: 2 sang thương mới khác nhau, có thể nối nhau với chiều dài > 22mm và ≤ 28mm Kích thước giá đỡ: đường kính: 2.5 và 3 mm chiều dài 18 và 28 mm ABSORB EXTEND Kết quả lâm sàng tạm thời... cáo và thời gian phóng thích thuốc ABSORB cohort B 101 bệnh nhân (không được chọn ngẫu nhiên) tại 12 trung tâm ở Châu Âu, Úc và New Zealand Mục tiêu nghiên cứu: tính an toàn và tính khả thi Tiêu chí đánh giá: tiêu chí hình ảnh học và lâm sàng kinh điển Sang thương: có thể tới 2 sang thương mới ở 2 mạch khác nhau có đường kính mạch máu 3mm và chiều dài chỗ hẹp ≤ 14 mm Kích thước giá đỡ: 3.0 x 18 mm ABSORB. .. dấu một bệnh nhân sau 2 năm theo dõi Không huyết khối theo ARC MACE: cardiac death, MI, ischemia-driven TLR TVF: cardiac death, MI, ischemia-driven TLR, ischemia-driven TVR ABSORB cohort B Kết quả khả quan tương tự stent phủ thuốc loại tốt nhất KM estimate of MACE rate in ABSORB cohort B (n=101) vs SPIRIT I+II+III (3 x 18 mm single metallic EES, n = 227) ABSORB cohort B Tăng đường kính mạch máu muộn ABSORB. .. bán cấp Ca 1: huyết khối bán cấp xảy ra vào ngày 6, cố gắng đi qua sang thương nhiều lần, bung giá đỡ Absorb 3 lần, sang thương vôi hóa trung bình đến nặng, chồng nối giá đỡ, IFU nhiều lần Ca 2: huyết khối bán cấp ngày 29, BN ngưng Plavix 1 ngày trước đó Tỉ lệ huyết khối bán cấp: Stent XIENCE V trong 30 ngày là 0,4% (SPIRIT III) Stent ENDEAVOR I và III trong 6 tháng là 1.0% và 0.5% ABSORB Clinical Trial... the composite of cardiac death, MI, and ischemia-driven TLR *P-value is not from formal hypothesis testing and is displayed for descriptive purpose only ABSORB EXTEND Kết quả lâm sàng tạm thời sau 6 tháng (n= 269) Intent to Treat (ITT) Analysis – Interim Snapshot *P-value is not from formal hypothesis testing and is displayed for descriptive purpose only ABSORB EXTEND Kết quả lâm sàng tạm thời sau... metallic EES, n = 227) ABSORB cohort B Tăng đường kính mạch máu muộn ABSORB cohort B Tính mềm dẻo ABSORB cohort B Tính mềm dẻo Prescaffold Curvature Scaffold, mm-1 Angulation, ° Tortuosity Postscaffold p-Value 0.038 0.031 . Chương trình nghiên cứu ABSORB và ca lâm sàng tại Bệnh Viện Chợ Rẫy PGS TS Võ Thành Nhân ĐH Y Dược – BV Chợ Rẫy TP HCM Các bước ngoặc trong lịch sử TMH can thiệp 1977 Balloon. 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