THÔNG TIN TÀI LIỆU
BIOACTIVE FOOD PEPTIDES
IN HEALTH AND DISEASE
Edited by Blanca Hernández-Ledesma
and Chia-Chien Hsieh
Bioactive Food Peptides in Health and Disease
http://dx.doi.org/10.5772/3318
Edited by Blanca Hernández-Ledesma and Chia-Chien Hsieh
Contributors
Blanca Hernández-Ledesma, Ben O. de Lumen, Chia-Chien Hsieh, Alfonso Clemente, Maria del
Carmen Marín-Manzano, Maria del Carmen Arques, Claire Domoney, Roseanne Norris, Richard
J. FitzGerald, Tânia G. Tavares, F. Xavier Malcata, Adham M. Abdou, Mujo Kim, Kenji Sato,
Anne Pihlanto, Sari Mäkinen, Maira R. Segura-Campos, Luis A. Chel-Guerrero, David A.
Betancur-Ancona, Kuo-Chiang Hsu, Yu-Shan Tung, Shih-Li Huang, Chia-Ling Jao, Sameh
Sarray, Jose Luis, Mohamed El Ayeb, Naziha Marrakchi, Claudia Muro, Francisco Riera, Ayoa
Fernández
Published by InTech
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Copyright © 2013 InTech
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Publishing Process Manager Petra Nenadic
Typesetting InTech Prepress, Novi Sad
Cover InTech Design Team
First published January, 2013
Printed in Croatia
A free online edition of this book is available at www.intechopen.com
Additional hard copies can be obtained from orders@intechopen.com
Bioactive Food Peptides in Health and Disease,
Edited by Blanca Hernández-Ledesma and Chia-Chien Hsieh
p. cm.
ISBN 978-953-51-0964-8
Contents
Preface IX
Section 1 Health Benefits of Food Peptides 1
Chapter 1 1997-2012: Fifteen Years of Research on Peptide Lunasin 3
Blanca Hernández-Ledesma, Ben O. de Lumen
and Chia-Chien Hsieh
Chapter 2 Bowman-Birk Inhibitors from Legumes:
Utilisation in Disease Prevention and Therapy 23
Alfonso Clemente, Maria del Carmen Marín-Manzano,
Maria del Carmen Arques and Claire Domoney
Chapter 3 Antihypertensive Peptides from Food Proteins 45
Roseanne Norris and Richard J. FitzGerald
Section 2 Foods as Source of Bioactive Peptides 73
Chapter 4 Whey Proteins as Source
of Bioactive Peptides Against Hypertension 75
Tânia G. Tavares and F. Xavier Malcata
Chapter 5 Functional Proteins and Peptides of Hen’s Egg Origin 115
Adham M. Abdou, Mujo Kim and Kenji Sato
Chapter 6 Antihypertensive Properties
of Plant Protein Derived Peptides 145
Anne Pihlanto and Sari Mäkinen
Chapter 7 Vigna Unguiculata as Source of Angiotensin-I Converting
Enzyme Inhibitory and Antioxidant Peptides 183
Maira R. Segura-Campos, Luis A. Chel-Guerrero and
David A. Betancur-Ancona
Chapter 8 Dipeptidyl Peptidase-IV Inhibitory Activity of Peptides
in Porcine Skin Gelatin Hydrolysates 205
Kuo-Chiang Hsu, Yu-Shan Tung, Shih-Li Huang and Chia-Ling Jao
VI Contents
Chapter 9 Snake Venom Peptides:
Promising Molecules with Anti-Tumor Effects 219
Sameh Sarray, Jose Luis, Mohamed El Ayeb and Naziha Marrakchi
Section 3 Production of Bioactive Food Peptides 239
Chapter 10 Advancements in the Fractionation of Milk Biopeptides
by Means of Membrane Processes 241
Claudia Muro, Francisco Riera and Ayoa Fernández
Preface
In recent years, nutrition and food sciences have been focused on biologically active
peptides present in the sequences of food proteins. Such peptides are inactive within
the sequence of the precursor proteins and can be released by enzymatic proteolysis
during gastrointestinal digestion or during food processing. Liberated peptides may
act as regulatory compounds with hormone-like activity in the human body. To date,
food-derived peptides with antihypertensive, antimicrobial, antioxidant, anti-
carcinogenic, anti-inflammatory, opioid agonist or antagonist, antiviral, among others,
have been characterized. These peptides possess properties that help to prevent and/or
treat different disorders, maintaining the well-health status of humans.
Bioactive Food Peptides in Health and Disease provides a general overview of food-
derived peptides for the promotion of human health and the prevention/management
of chronic diseases. The book provides updated and interesting information on
bioactive peptides obtained from both animal and plant food sources, emphasizing on
important aspects related to their bioactivity, mechanism of action, and bioavailability.
Also, the chapters describe the impact of bioactive peptides on the physiological
absorption, regulation and disease prevention. The book also covers the recent
technological advances for the production of food peptides.
The editors want to thank the authors for their important contribution to the success of
this book. They are eminent researchers all over the world that have accepted to share
and turn their ideas and work into a book that we hope to be an essential resource and
reference for nutritional and food scientists, biochemists, industry producers and
consumers.
Dr. Blanca Hernández-Ledesma
Institute of Food Science Research (CIAL, CSIC-UAM), Madrid,
Spain
Dr. Chia-Chien Hsieh
Department of Nutritional Science and Toxicology.
University of California, Berkeley, California,
USA
. BIOACTIVE FOOD PEPTIDES
IN HEALTH AND DISEASE
Edited by Blanca Hernández-Ledesma
and Chia-Chien Hsieh
Bioactive Food Peptides in. chronic diseases. The book provides updated and interesting information on
bioactive peptides obtained from both animal and plant food sources, emphasizing
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