MouseModels of Cell Cycle Regulators - New Paradigms
MouseModels of Cell Cycle Regulators - New Paradigms
... Mouse Models of Cell Cycle Regulators: New Paradigms 291
3.5
Placental Defects and Endoreduplication
Ablation of cell cycle genes in mice sometimes leads to extra-embryonic de-
fects that compromise ... Models of Cell Cycle Regulators: New Paradigms 293
Collectively speaking, ablation of three different cell cycle genes DP-1,
Rb or cyclin E (E1 and E2) result...
Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... proteins Lin-37, Lin-52, Lin-54 and chromatin-
associated Lin-9 and Lin-53 ⁄ RBBP4 ⁄ RbAp48.
Furthermore, A-Myb and B-Myb were present in
immunoprecipitations for Lin-9, Lin-37 and Lin-54
[90,92]. ... compared with
wild-type cells when assayed using in vivo footprinting.
Loss of the two pocket proteins leads to deregulation
of the B-Myb promoter during the cell cycle. Re-intro-
duction...
The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis
... accompanied by a high cell turn-
over as a result of p53-dependent apoptosis. Expression of the T
121
variant of
T-antigeninaBax-, p53-orE2F-1 deficient background results in accelera-
198 J H.Dannenberg·H.P.J.teRiele
tion ... critical regulator of most
cell cycle responses. While each single pocket protein can mediate cell cycle
arrest upon cell- cell contact, pRb is the cr...
Báo cáo " Cell suspension culture Panax ginseng C. A. Meyer: Role of plant growth regulators and medium composition on biomass and ginsenoside production " docx
... culture characteristics of
the suspended cells of ginseng in shake flask,
the effect of plant growth regulators (2,4-D or
IBA or NAA combination with BA or kinetin)
on cell growth, ginsenoside ... established cell suspension
culture of ginseng cell and some attempts have
been made to increase biomass and ginsenoside
yield of ginseng cell culture.
2. Materials and m...
Báo cáo khoa học: Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex doc
... the RP of
the mammalian cell cycle using a yeast-like core model
of the cyclin–Cdk interactions (emphasizing the deep
similarities of the Cdk-regulatory systems of yeast and
mammalian cells). ... 30 h is shown for six of the intermediates of the
system. The G 1-, S/G 2- and M-phases for one cell cycle are indi-
cated in the graph. The RP is also depicted in the G1-pha...
Báo cáo khoa học: Site-specific phosphorylation of MCM4 during the cell cycle in mammalian cells pot
... G
2
-0 .4
-0 .2
0
0.2
0.4
0.6
0.8
1
1.2
1.4
1.6
P-3Ab
P-7Ab
P-19Ab
P-32Ab
P-54Ab
P-110Ab
A
450
P-Ser3 P-Thr7 P-Thr19
P-Ser54
P-Ser32
P-Thr110
phosphopeptides
Fig. 2. Specificity of binding of phospho-
MCM4 antibodies. The ... anti-MCM4 or an-
tiphosphoMCM4 (P-3, -7 , -1 9, -3 2, -5 4, -8 8
and -1 10) sera as indicated. Arrows on the
right-hand side of gel indicate...
Báo cáo khoa học: Injection of poly(b-L-malate) into the plasmodium of Physarum polycephalum shortens the cell cycle and increases the growth rate pot
... S-phase and G
2
-phase of the cell cycle
but not in G
1
-phase have been reported for HeLa cells [26].
In some other mammalian cells, examples of cytoplasmic
accumulation of H1, but not of core histones ... analysis of DNA
synthetic activities in extracts of plasmodia revealed a cell
cycle dependent inhibition and activation of DNA poly-
merases. This could be explained...
Plant physiology - Chapter 21 Cytokinins: Regulators of Cell Division doc
... CH
3
CH
2
OH
CH
2
N
N
H
N
CC
H
N
HN
CH
3
CH
2
trans-Zeatin
6-( 4-Hydroxy-3-methylbut-2-enylamino)purine
cis-Zeatin
N
C
C
O
C
CC
H
H
H
H
H
C
N
C
C
C
N
N
C
N
H
H
H
9
1
2
3
4
5
6
7
8
H
Kinetin
Amino
purine
Cytokinins: Regulators of Cell Division ...
Disruption of
ARR1, one of the type-B ARR genes,
reduces the induction of the type-A
ARR genes in response
Cytokinins: Regulators...
Báo cáo Y học: Synthesis and turn-over of the replicative Cdc6 protein during the HeLa cell cycle potx
... the synthesis of new Cdc6p.
In contrast, the rapid S-phase-related elimination of
Cdc6p that is characteristic for the yeast cell cycle does not
occur i n mammalian cells, and levels of human Cdc6p
(hCdc6p) ... transferred to n itro-
cellulose membranes. Immunostaining showed that cells in
all cell cycle phas es possess substantial amounts o f chroma-
tin-bound hCdc6p although...
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