In vitro and in vivo evaluation of customized polycaprolactone tricalcium phosphate scaffolds for bone tissue engineering

... submitted for the degree of Master of Engineering in the Department of Mechanical Engineering at the National University of Singapore under the supervision of Professor Teoh Swee Hin and Dr Alvin Yeo ... secrete bone tissue and form the tissue around itself like a protective wall of bone tissue They are responsible for the maintenance of healthy bone by...

Ngày tải lên: 09/10/2015, 11:18

... IMPROVING THE MECHANICAL AND FUNCTIONAL PERFORMANCE OF EXTRUSION- BASED ADDITIVE MANUFACTURED SCAFFOLDS FOR BONE TISSUE ENGINEERING MUHAMMAD TARIK ARAFAT (B.Sc in Mechanical Engineering, ... mechanical and functional performance of extrusion- based additive manufactured scaffolds. ” The main objective of this study was therefore to devel...

Ngày tải lên: 10/09/2015, 15:51

... Performer and the Hygrobac had significantly higher airway temperature and AH than did the Hygroster (Fig 5) Active Performer, regardless of the level of heating, always had a higher temperature and AH ... inspiratory flow; VT = tidal volume Statistical analysis All data are expressed as mean ± standard deviation For the in vitro study, we compared the three HMEs using a o...

Ngày tải lên: 12/08/2014, 20:20

... IN VITRO AND IN VIVO EVALUATION OF TRANSFERRIN- CONJUGATED LIPID SHELL AND POLYMER CORE NANOPARTICLES FOR TARGETED DELIVERY OF DOCETAXEL PHYO WAI MIN (M.B.,B.S (YGN) U.M(1)) ... the synthesis and characterization of transferrin conjugated lipid shell and polymer core nanoparticles are discussed in Chapter In Chapter 5, in vitro...

Ngày tải lên: 09/10/2015, 11:18

... stability of PANs was studied in the aqueous medium, and the acute toxicity of PANs was evaluated in mice Morever, EPI was loaded into PANs and its pharmacokinetics was also assessed in rats to compare ... main pharmacokinetic parameters were calculated by DAS 1.0 (Anhui, China) program Bioavailability (BA) is a measurement of the rate and extent of a therapeutically...

Ngày tải lên: 23/04/2013, 21:38

... with variable HA concentrations, and reversibility of HA effect In vitro effect of several .hyaluronic acid (HA) concentrations on rigidity index (RI) Each sample was fractioned in aliquots (1 ml) ... interpretation of data of erythrocyte aggregation of the in vitro experiments GP: acquisition, analysis and interpretation of data of erythrocyte deforma...

Ngày tải lên: 10/08/2014, 05:21

... bone tissue engineering for an ideal bone substitute 1.1.3 Strategies in BTE Tissue engineering is the restoration, improvement, maintenance and substitution of damaged tissues and organs using ... will be in solutions (Lakes, 2007) TCP is found naturally in the inorganic phase of bone in form of hydroxyapatite TCP is also responsible for the hardness...

Ngày tải lên: 09/10/2015, 11:18

... the herceptin conjugated liposomes Thus the herceptin conjugated Vitamin E TPGS coated liposomes showed greater potential for sustained and targeted chemotherapy in the treatment of HER2 over expressing ... have been discovered and developed since the past few decades Together with the problems faced in traditional ways in which cancer patients are treated, this regi...

Ngày tải lên: 09/10/2015, 11:18

... stages and canal and reinserting the prosthesis The FRF had a normal evolution during the reinsertion and the graphs corresponding to the final two stages, labelled as stage 4a and stage 5a, are ... the FRF analysis showed an abnormality and the surgeon was alerted to the situation in time during insertion of the stem (Figures 7a c) The supplementary information o...

Ngày tải lên: 20/06/2014, 01:20

... and titanium-coated implants in rabbit bone Int J Oral Maxillofac Implants 1992, 7:485-490 35 Soballe K: Hydroxyapatite ceramic coating for bone implant fixation Mechanical and histological studies ... implant was press-fit into the intramedullary canal through a drill hole in the intercondylar notch of the femur Bilateral implantation was used to reduce any bias introdu...

Ngày tải lên: 20/06/2014, 04:20

... suggesting particle size > µm in diameter At no point did any of the Research paper Evaluation of incompatible drugs in a venous catheter Reyes et al samples, control or study, fail to pass a µm aperture ... data are handled according to current College of American Pathologists’ standards Calibration of the analyzer is checked quarterly using a commercial calib...

Ngày tải lên: 12/08/2014, 18:20

... Access CdTe quantum dots with daunorubicin induce apoptosis of multidrug-resistant human hepatoma HepG2/ADM cells: in vitro and in vivo evaluation Gen Zhang1, Lixin Shi2, Matthias Selke2 and Xuemei ... Cite this article as: Zhang et al.: CdTe quantum dots with daunorubicin induce apoptosis of multidrug-resistant human hepatoma HepG2...

Ngày tải lên: 21/06/2014, 03:20

... amplification with primers 5¢-GCGGAGCTCATGGCCAC AAGCGCATCAGC-3¢ and 5¢-GTGGTGGTGGTGGTGG TGGAAATGGGTTTTTCCGTTCTGC-3¢ (His-tag underlined) or 5¢-TGGAGCCACCCGCAGTTCGAAAAAGAA GCTGGAGATGATCGTGCT-3¢ (Strep-tag ... template Primers were designed as follows: PSAG with a C-terminal hexa-histidine tag (PSI -G- HisTerm), 5¢-GCGGAGCTCAT GGCCACAAGCGCATCAGC-3¢ and 5¢-GCGGCATGCT CAGTGGTGGTGGTGGTGGTGTCCAA...

Ngày tải lên: 07/03/2014, 21:20

... and cellular responses; and analysis of T-cell proliferation LG contributed to CIA induction and evaluation and to analysis of T-cell proliferation PM contributed to the design of the study and ... inhibition of T-cell proliferation was demonstrated by the addition of inhibitors of these enzymes - GW274150 and indomethacin [8,36], respectively - to t...

Ngày tải lên: 12/08/2014, 11:23

... point, a direct comparison of the pathogenecity of these strains is difficult to make In this context, the aim of the present study is to compare the in vitro and in vivo properties of these two ... to the sensitivity of the ELISA test available In the case of animal 191, as discussed above, the reason could have been the lack of infection P...

Ngày tải lên: 12/08/2014, 18:22