Generation of porcine induced pluripotent stem cells and their differentiation into cardiac lineages

... GENERATION OF PORCINE INDUCED PLURIPOTENT STEM CELLS AND THEIR DIFFERENTIATION INTO CARDIAC LINEAGES TAN WAN CHIU GRACE (B.Eng.(Hons.), NTU) A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF ... generate porcine induced pluripotent stem cells (IPSCs) from porcine fibroblast cells and differentiate such cells into cardiac lineages to provide a...

Ngày tải lên: 30/09/2015, 10:13

... SCREEN OF NUCLEAR RECEPTORS FOR THE ENHANCED AND ALTERNATIVE GENERATION OF INDUCED PLURIPOTENT STEM CELLS DOMINIC HENG JIAN CHIEN (B.Sc (Hons), NTU) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR ... akin to pluripotent embryonic stem cells (ESCs) and pluripotent cells of the early embryo, thus gaining their characteristic developmental potenti...

Ngày tải lên: 09/09/2015, 18:56

... Rada-Iglesias A, Wysocka J: Epigenomics of human embryonic stem cells and induced pluripotent stem cells: insights into pluripotency and implications for disease Genome Medicine 2011, 3:36 ... Feinberg AP: Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem...

Ngày tải lên: 11/08/2014, 12:21

... doi:10.1186/gm265 Cite this article as: Israel MA, Goldstein LSB: Capturing Alzheimer’s disease genomes with induced pluripotent stem cells: prospects and challenges Genome Medicine 2011, 3:49 ... GQ, Porteus MH, Joung JK, Cheng L: Gene targeting of a disease- related gene in human induced pluripotent stem and embryonic stem cells Cell Stem Cell 2009, 5:97-1...

Ngày tải lên: 11/08/2014, 12:21

... R: Nuclear reprogramming and pluripotency Nature 2006, 441:1061-1067 Takahashi K, Yamanaka S: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined ... JA: Induced pluripotent stem cell lines derived from human somatic cells Science 2007, 318:1917-1920 Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S: Generation of mouse...

Ngày tải lên: 14/08/2014, 21:20

... 2011 doi:10.1186/gm284 Cite this article as: Yeo J-C, Ng H-H: Transcriptomic analysis of pluripotent stem cells: insights into health and disease Genome Medicine 2011, 3:68 ... developmental defects and mental retardation due to dysregulation of gene expression [29] ESC, embryonic stem cell; hiPSC, human induced pluripotent stem cell; iPSC, induced pluripotent...

Ngày tải lên: 11/08/2014, 12:21

... intravenously injected into nude mice and the distribution and migration of MSCs were dynamically monitored to evaluate the feasibility and safety of intravenous implantation of allogeneic MSCs in the ... transplanted the bone marrow stem cells into the necrotic femoral heads, and results show bone marrow stem cells can remove vascular lesions...

Ngày tải lên: 25/10/2012, 11:18

... http://books.nap.edu/catalog/.html STEM CELLS AND THE FUTURE OF REGENERATIVE MEDICINE the research met the highest scientific and ethical standards If the federal government chooses to fund research on human embryonic stem cells, ... http://books.nap.edu/catalog/.html STEM CELLS AND THE FUTURE OF REGENERATIVE MEDICINE information presented, explored...

Ngày tải lên: 15/03/2014, 09:20

... culture, expansion and manipulation of human pluripotent stem cells The culmination of two events has enabled the production of human embryonic stem cells: the birth of the first IVF test-tube baby ... summarizing 12 years of our team’s experience, skill and knowledge in the derivation, culture and expansion of human embryonic stem cells, and more recently, of...

Ngày tải lên: 22/03/2014, 09:20

... gene signaling pathway analysis has identified gene signals that are remarkably activated in AT-MSC-Hepa, and these signals are also up-regulated in whole liver Therefore, the microarray analysis ... protocol, and then treated with deoxyribonuclease (DNase I, amplification grade; TaKaRa, Kyoto, Japan) Microarray analysis and data mining (Aligent array) A one-color microarray...

Ngày tải lên: 30/03/2014, 04:20

... administration, the ability to migrate to sites of T cell activation and generation of CTLs Activated and mature DCs results in antigen-specific immunity, while fully immature and inactivated ... class I hTERT pulsed DCs Vaccinations with DCT and DCTI in 10 patients Both vaccines (DCT and DCTI) were equivalent in eliciting CD8 +T cell responses and there were...

Ngày tải lên: 18/06/2014, 15:20

... The effects of growth factors on the production of osteopontin and osteocalcin Biomed Sci Instrum 2006, 42:31-36 Gonnerman KN, Brown LS, Chu TM: Effects of growth factors on cell migration and ... coating on osteoblast like cells and pluripotent mesenchymal cells is also in accordance with previous studies [8,25,26] The proliferating effect of the...

Ngày tải lên: 20/06/2014, 01:20

... mechanical, whereas both mechanical and vascular factors were involved in balloon compression Transplantation of ASCs in spinal cord injury 279 Fig Images of the spinal cord injury lesion A: control ... we examined whether canine ASCs could survive and integrate into neural cells and the effectiveness of canine ASCs on the improvement of neurological funct...

Ngày tải lên: 07/08/2014, 23:22