Molceular genetics of y chromosome in male infertility

... Dicentric iso-Yp chromosomes and; (C) ring -Y chromosome are often found together with a 45,XO cell line in the patient’s lymphocyte nuclei pointing to the instability of the Y chromosome after ... disorders Finally, an essentially complete physical map of the Y chromosome was generated with 196 overlapping DNA clones by a library of yeast artificial clones (YAC) from a hum...

Ngày tải lên: 16/09/2015, 15:53

... was the trait measured of the pth animal in the ijklmnoth class, p klmno i ! the overall mean, A the fixed effect of the ith year, UB the fixed effect of j unilateral/bilateral laying-pair, B! the ... animal in the ijklth class, p , ijkl the overall mean, A the fixed effect of the ith year, UB the fixed effect of i j unilateral/bilateral laying-pair, GZ...

Ngày tải lên: 09/08/2014, 18:22

... Mutations  in TRPC6  resulted in a gain of function.  Mutations in WT1 affect the DNA‐binding affinity of WT1  to the target gene. Heterozygous de novo mutations in WT1 resulting in the inability of ... C‐terminal  domain of podocin (Huber et al., 2001). The phosphorylation of nephrin also increases  the binding of nephrin and podocin (Li et al., 2004).     TRPC6  TRPC6  is  a  member  of t...

Ngày tải lên: 07/10/2015, 10:02

...   (20 11)  Diagnosis  Gender 22 0  10  4  M  22 3  6  5  F  23 1  11  9  M  23 2  6  3  M  23 5  18  9  M  23 6  10  7  M  23 9  21   3  M  24 4  9  2 M  25 2  19  17  M  25 3  4  4  M  25 4  14  11  M  25 5  ... A/A  A/A  154 Patient  no.  153  156  159  160  161  1 62 164  169  170  1 72 173  174  21 0  21 6  22 0  22 3  23 1  23 2  23 5  23 6  23 9  24 4  25 2  25...

Ngày tải lên: 12/10/2015, 17:35

... DISCUSSION The findings in this study show that GR is highly expressed in epithelial cells of the male genital tract, especially in the Ó FEBS 2002 Glutathione reductase in male reproduction system ... level of expression of aldose reductase was also detected in the epithelia of the male genital tract In addition, glutathione S-transferase is pre...

Ngày tải lên: 17/03/2014, 17:20

... decreased activity of regulatory T cells The aim of this study was to analyze the association of the 1858C/T SNP with RA in a sample set comprising 390 German white RA cases and 349 healthy German ... both male and female patients compared to the appropriate controls (Table 3) However, the frequency of a PTPN22 1858T genotype was significantly high...

Ngày tải lên: 09/08/2014, 08:22

... level of joint damage in RA is therefore required The increasing comprehension of the role of genetics in disease outcome in RA may promote the development of personalized medicine Although the ... frequently in relation to RA, providing inconsistent results, is a noncoding variant in the 3′ end of the gene encoding for cytotoxic T lymphocyte antigen (CTL...

Ngày tải lên: 09/08/2014, 10:23

... and ankylosing spondylitis As discussed in the Introduction, twin and family studies have long suggested the existence of non-MHC susceptibility genes for AS In 2007 a study of 14,500 nonsynonymous ... [20] The recent report of cases of AS occurring in individuals carrying the B*2709 subtype has raised the question of whether this subtype is protective against AS...

Ngày tải lên: 09/08/2014, 14:20

... dermatofibrosarcoma protuberans on the breast of a Chinese man Diagnostic work-up comprised clinical examination, mammography and magnetic resonance imaging (MRI), and diagnosis was proved by both ... sequences in axial and sagittal planes; T1- and T2-weighted imaging fat- Figure Axial mammography shows a subcutaneous oval mass with a smooth and sharp margin on...

Ngày tải lên: 11/08/2014, 14:20

... EQ, Bassett LW: Imaging characteristics of malignant lesions of the male breast Radiographics 2006, 26:993-1006 Nahleh ZA: Hormonal therapy for male breast cancer: A different approach for a different ... RC: Adjuvant chemotherapy in males with cancer of the breast Am J Clin Oncol 1987, 10:55-60 Patel HZ, Buzdar AU, Hortobagyi GN: Role of adjuvant chemotherap...

Ngày tải lên: 11/08/2014, 23:21

... triiodothyronine (T Effects of phytoestrogens on the plasma free Effects of phytoestrogens on the plasma free triiodothyronine (T3) concentrations in male goat kids Goat kids at the age of months ... 13 Effects of phytoestrogens on the plasma testosterone conFigure centrations in male goat kids Effects of phytoestrogens on the plasma...

Ngày tải lên: 12/08/2014, 18:22

... for both the formation and the maintenance of the myosin II ring The oocyte cortex underwent distinct protrusion and invagination which led to polar body extrusion Meiotic spindles in the MII ... cortical furrowing during polar body extrusion The chromosome-induced spindle and cortical actomyosin cap play distinct roles in polar body extrusion (Figure 5)...

Ngày tải lên: 13/08/2014, 18:21

... staining pattern, including D simulans, D yakuba, and D pseudoobscura (data not shown) In D melanogaster, staining with an antibody against histone H3 methylated at lysine (antiH3K9me) coincides ... fosmids from the dot chromosome of D virilis Comparison of the sample from the dot chromosome of D melanogaster analyzed here to the entire banded portion of the do...

Ngày tải lên: 14/08/2014, 16:21

... modulation in RNA levels without changes in copy number of a gene is an infrequent event in drug resistant Leishmania The use of both L infantum and L major MTX resistant mutants validated the design of ... one of the first and most widely used drugs for understanding drug- induced plasticity and resistance mechanisms [5-8] While Leishmania is sensitive to...

Ngày tải lên: 14/08/2014, 20:22

... assessment of the availability of key resources to treat victims of sexual violence in hospitals regularly caring for victims of sexual violence; and (3) assessment of the frequency of delivery of three ... appropriately care for victims of sexual violence During the observation period, 7,048 females sought medical care because of physical or p...

Ngày tải lên: 25/10/2012, 10:06