Crystal structure of arabidopsis thaliana cyclophilin 38 (atcyp38 2

... YDGMEIQRSD TEKTRTVPLE YKAQVVIPFN VFWLLKESEL NEDFLADLKV YKIAG 437 1 12 1 42 1 72 2 02 2 32 2 62 2 92 322 3 52 3 82 4 12 Figure 28 The sequence of AtCyP38 (83-437) The native methionine residues are highlighted ... 98.1(93.3) 98 .2 (90.9) 98.6 (91.6) Redundancy 6 .2 (5.7) 6.3 (6.0) 6 .2 (5.7) Rsym 0.069 (0 .29 ) 0.059 (0.30) 0.065 (0 .25 ) 0.067 (0 .23 ) 〈I/σ(I)〉 0.9500 21 .4...

Ngày tải lên: 14/09/2015, 17:50

... 1994 Functional association of cyclophilin A with HIV-1 virions Nature 37 2: 36 3 -36 5 Vajdos FE, Yoo SH, Houseweart M, Sundquist WI, Hill CP 1997 Crystal structure of cyclophilin A complexed with ... Biol Chem 274: 34 877 -34 8 83 Dornan J, Taylor P, Walkinshaw MD 20 03 Structures of immunophilins and their ligand complexes Curr Top Med Chem 3: 139 2-1409 Doublie S 1997...

Ngày tải lên: 14/09/2015, 17:49

... problem 15 1. 4 GEOMETRIC DATA COLLECTION 16 1. 4 .1 Data reduction 17 iv 1. 5 STRUCTURE DETERMINATION 18 1. 5 .1 Phasing methods 18 1. 5 .1. 1 The Multi-wavelength anomalous dispersion (MAD) method 21 1.5 .1. 2 ... PSBQ 10 8 4 .11 FUTURE DIRECTIONS 11 3 4 .12 CONCLUDING REMARKS 11 3 REFERENCES 11 5 viii SUMMARY Cyclophilin 38 (CyP38) is one of the highly divergent mu...

Ngày tải lên: 14/09/2015, 17:52

... differences from the analogous structures of the ascomycete laccase (asco -laccase) MaL, thus giving a comprehensive view of the structure and function of asco-laccases Results and Discussion Overall structure ... Thornton JM (2003) Structural characterization and functional significance of transient protein–protein interactions J Mol Biol 325, 99 1–1 018 Crystal str...

Ngày tải lên: 14/02/2014, 18:20

... A2 for main-chain atoms, 35.7 A2 for side-chain ˚ overall (3 244 atoms) For the pepatoms and 33.8 A tide, B factors are slightly higher than those for ˚ ˚ importin -a: 36.9 A2 for main-chain atoms, ... atoms, 40 .2 A2 for ˚ overall (62 total atoms) side-chain atoms and 38.7 A Electron density analysis Both the main-chain and side-chain atoms of the modelled CLIC4 peptide...

Ngày tải lên: 14/02/2014, 19:20

... illustrates the superimposition of ApeSOD with the cambialistic SOD from P shermanii The overall structures of these enzymes were similar; the rmsd of the 747 Ca atoms was ˚ 0.695 A ApeSOD eluted from the ... superoxide dismutases Biochim Biophys Acta 1804, 24 5–2 62 Crystal structure of SOD from A pernix K1 Sugio S, Hiraoka BY & Yamakura F (2000) Crys...

Ngày tải lên: 14/02/2014, 22:20

... substrate recognition For the superposition of the substrate- free PhyK with substrate- free ˚ AppA the Ca atoms are 2.41 A apart, whereas for the substrate- free PhyK and the substrate- loaded AppA ... B Fig Crystal structure of Klebsiella sp ASR1 phytase (A) Cartoon representation showing the two domains of PhyK, the a domain (orange) and the a ⁄...

Ngày tải lên: 16/02/2014, 09:20

... number of Arabidopsis transcripts are potential targets for regulation by the PUF family of proteins The results obtained reveal a molecular conservation of PUF proteins in Arabidopsis thaliana and ... regarding the binding specificity of the subset of group I APUM proteins, showing that A thaliana has at least six PUF proteins with conserved RNA -binding...

Ngày tải lên: 18/02/2014, 06:20

... 14-48 form the small insertion domain that comprises a short a- helix and a three-stranded anti-parallel b-sheet; the remaining protein residues form the (a ⁄ b)8 barrel domain and a C-terminal extension ... would act as a regulatory link between glycolysis and NAD synthesis The structure of hACMSD in complex with DHAP may used for the design o...

Ngày tải lên: 18/02/2014, 06:20

... structure of the catalytic domain of DESC1 Scheme Domain organization of human DESC1 membrane region The extracellular part of DESC1 consists of a 120-amino acid SEA domain followed by the C-terminal ... growth factors and proteinase inhibitors Biol Chem 380, 473–483 Kataoka H, Uchino H, Asada Y, Hatakeyama K, Nabeshima K, Sumiyoshi A & Koono M (1997) Analy- C...

Ngày tải lên: 19/02/2014, 00:20

... References Ivanova N, Sorokin A, Anderson I, Galleron N, Candelon B, Kapatral V, Bhattacharyya A, Reznik G, Mikhailova N, Lapidus A et al (2003) Genome sequence of Bacillus cereus and comparative analysis ... of GAB catalysis have been identified to date [12] which are based either on a single, bifunctional GAB catalyst or on a GAB catalysts pair The available biochemical dat...

Ngày tải lên: 19/02/2014, 00:20

... (2002) A novel interaction partner for the C-terminus of Arabidopsis thaliana plasma membrane H+-ATPase (AHA1 isoform): site and mechanism of action on H+-ATPase activity differ from those of 14-3-3 ... Rasi-Caldogno F (1998) Fusicoccin binding to its plasma membrane receptor and the activation of the plasma membrane H+-ATPase IV Fusicoccin induce...

Ngày tải lên: 19/02/2014, 07:20

... the carboxyl oxygen atoms of the side chains of Asp11, Asp14 and Asp21, the amide oxygen atom of Gln15 and the carbonyl oxygen atoms of Asp11 and Asn23 (Fig 3) in an arrangement similar to what ... within a few days to thin hexa62 Table Data collection and refinement statistics for SPRK ˚ Resolution (A) Space group Cell parameters ˚ a- axis (A) ˚ b-axis (A) ˚...

Ngày tải lên: 19/02/2014, 07:20

... of cold adaptation ase structure, the first structure of a cold- adapted subtilase to be determined, enables a more focused examination of plausible determinants of different temperature adaptation ... Number of ion pairsa Number of hydrogen bonds Main chain–main chain Main chain–side chain Side chain–side chain Total ˚ Exposed surface areab (A2 ) ˚ Apolarc (A2 ) ˚ Bu...

Ngày tải lên: 19/02/2014, 16:20

... effect of these substrate analogues This is consistent with a simultaneous interaction of the 1,3BPGA analogues at both Ps and Pi phosphate-binding sites Comparison of the inhibition of T cruzi and ... specific binding modes of these 1,3-BPGA analogues to the two trypanosomatid enzymes Materials and methods Sources of substrates, cofactors and inhibitors The synthesis of 1,...

Ngày tải lên: 20/02/2014, 02:21