Screen of nuclear receptors for the enhanced and alternative generation of induced pluripotent stem cells

... SCREEN OF NUCLEAR RECEPTORS FOR THE ENHANCED AND ALTERNATIVE GENERATION OF INDUCED PLURIPOTENT STEM CELLS DOMINIC HENG JIAN CHIEN (B.Sc (Hons), NTU) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR ... akin to pluripotent embryonic stem cells (ESCs) and pluripotent cells of the early embryo, thus gaining their characteristic developmental potenti...

Ngày tải lên: 09/09/2015, 18:56

... Rada-Iglesias A, Wysocka J: Epigenomics of human embryonic stem cells and induced pluripotent stem cells: insights into pluripotency and implications for disease Genome Medicine 2011, 3:36 ... Feinberg AP: Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem...

Ngày tải lên: 11/08/2014, 12:21

... GENERATION OF PORCINE INDUCED PLURIPOTENT STEM CELLS AND THEIR DIFFERENTIATION INTO CARDIAC LINEAGES TAN WAN CHIU GRACE (B.Eng.(Hons.), NTU) A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF ... generate porcine induced pluripotent stem cells (IPSCs) from porcine fibroblast cells and differentiate such cells into cardiac lineages to provide a...

Ngày tải lên: 30/09/2015, 10:13

... culture, expansion and manipulation of human pluripotent stem cells The culmination of two events has enabled the production of human embryonic stem cells: the birth of the first IVF test-tube baby ... summarizing 12 years of our team’s experience, skill and knowledge in the derivation, culture and expansion of human embryonic stem cells, and more recently, of...

Ngày tải lên: 22/03/2014, 09:20

... doi:10.1186/gm265 Cite this article as: Israel MA, Goldstein LSB: Capturing Alzheimer’s disease genomes with induced pluripotent stem cells: prospects and challenges Genome Medicine 2011, 3:49 ... GQ, Porteus MH, Joung JK, Cheng L: Gene targeting of a disease- related gene in human induced pluripotent stem and embryonic stem cells Cell Stem Cell 2009, 5:97-1...

Ngày tải lên: 11/08/2014, 12:21

... R: Nuclear reprogramming and pluripotency Nature 2006, 441:1061-1067 Takahashi K, Yamanaka S: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined ... JA: Induced pluripotent stem cell lines derived from human somatic cells Science 2007, 318:1917-1920 Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S: Generation of mouse...

Ngày tải lên: 14/08/2014, 21:20

... Strategy for the Management and Disposal of Used Nuclear Fuel and High-Level Radioactive Waste INTRODUCTION AND SUMMARY The Strategy for the Management and Disposal of Used Nuclear Fuel and High-Level ... Management and Disposal of Used Nuclear Fuel and High-Level Radioactive Waste generators pay the full cost of...

Ngày tải lên: 21/02/2014, 21:20

... plays an important role in the regulation of immune central and peripheral tolerance, and hence in autoimmune reactivity of the immune system Autoimmunity Autoimmunity is the result of a loss of ... characteristic of self-autoreactivity [51-54] However, loss of any one of the receptors and/ or their ligands results in relatively mild defects compared with loss of...

Ngày tải lên: 09/08/2014, 10:23

... therefore in this paper a new transformation which preserves the same advantages as the Park transformation A Mathematical Model of the BDCM We suppose that the motor has the following typical features ... pulsating torque (the homopolar part) and a two-phase motor with a rotating field (the "ap" The classical Park transformation is, in fact, the succ...

Ngày tải lên: 03/01/2014, 19:44

... only the longest amino acid sequences that included the DNA binding, hinge and ligand-binding domains were used for this analysis, except for the Knirps family members that lack the LBD In D ... processes In A aegypti, the discrete expression of both AaHR3 and AaHR4 suggests their function in the regulatory hierarchy in the mosquito fat body during vitellogenesi...

Ngày tải lên: 18/02/2014, 13:20

... Ethical Journalism A Handbook of Values and Practices for the News and Editorial Departments “ Reporters, editors, photographers and all members of the news staff of The New York Times share ... careful about the use of their names and that of the newspaper in materials promoting the appearances As a courtesy, they should let their departm...

Ngày tải lên: 06/03/2014, 11:20

... Member States and other stakeholders and will support achievement of the goals of the global strategy for the prevention and control of noncommunicable diseases 09 2008-2013 Action Plan Purpose ... effectively the impact of noncommunicable diseases, ENDORSES the action plan for the global strategy for the prevention and contr...

Ngày tải lên: 07/03/2014, 04:20

... safety in the healthcare environment through appropriate use of PPE PPE Use in Healthcare Settings: Program Objectives • Provide information on the selection and use of PPE in healthcare settings ... safely don and remove PPE PPE Use in Healthcare Settings The objectives of this program are to provide information on the selection and use...

Ngày tải lên: 08/03/2014, 13:20

... segments of the oil and gas industry The final rules are the result of the review of four air regulations for the oil and natural gas industry required by the Clean Air Act: a new source performance ... performance standard for VOCs; a new source performance standard for sulfur dioxide; an air toxics standard for major sources of oil...

Ngày tải lên: 15/03/2014, 20:20