DIFFERENTIATION AND CONTRACTILITY OF COLON SMOOTH MUSCLE UNDER NORMAL AND DIABETIC CONDITIONS

... contraction. vi Abstract Ketrija Touw DIFFERENTIATION AND CONTRACTILITY OF COLON SMOOTH MUSCLE UNDER NORMAL AND DIABETIC CONDITIONS Intestinal smooth muscle development involves complex transcriptional ... Ca 2+ but it can transport calcium out of the cell rapidly. Differentiation and development of the colon smooth muscle Progenito...

Ngày tải lên: 24/08/2014, 12:32

... were harvestedafter0,0.5,1, 2and4 h.TotalRNAwaspurified and analyzed b y northern blot hybridization and phosphor- imaging densitometry. The relative amounts of normalized mRNA were plotted as a function of time and the ... 271) 4449 Regulation of connective tissue growth factor (CTGF/CCN2) gene transcription and mRNA stability in smooth muscle cells Involvement of RhoA GTP...

Ngày tải lên: 19/02/2014, 16:20

... including cell proliferation and differentiation, remains poorly understood. Vascular smooth muscle cells (SMC) are required to proliferate under pathological conditions and following revascularization ... blocked the stimulation of DNA and RNA synthesis, prevented smooth muscle cell migration and suppressed the induction of c-fos and c-myc gene expression. An exami...

Ngày tải lên: 17/03/2014, 09:20

... LUTS and/ or BPH). Fur- thermore, those with OAB had a worse quality of life score. Mean quality of life score for those with OAB was 3.4 of 6, and those without OAB 1.6. Thus, the 48% of men ... quality of life score. Mean quality of life score for those with OAB was 3.4 of 6, and those without OAB 1.6. Fur- thermore, 59% reported urge incontinence, 76% ur- gency, 90%...

Ngày tải lên: 25/10/2012, 11:35

... coating of a large variety of nanoparticles such as V 2 O 5 ,MoO 3 ,MgCNi 3 , MgCxCo 3 and WO 3 at elevated temperatures under autogenic pressure, and eventually producing a vari- ety of core-shell ... procedure of adding the precursor to a Letlok cell and heating at 600–1,000 °C under air or under inert atmosphere. Because of its P. P. George Á V. G. Pol Á A. Gedanken (...

Ngày tải lên: 22/06/2014, 22:20

... proliferation and migration. During this process SMCs undergo cellular remodelling and a number of smooth muscle- specific contractile pro- teins are converted to non -muscle isoforms. One of such signature ... 13% of the control cells (EGFP), and the ratios of A1A2 and A3A4 were 49% and 47% of the control cells, respectively. It seems that both Erk and PAK contribu...

Ngày tải lên: 10/08/2014, 05:21

... airways or within the smooth muscle cells of the airways. The release and per- sistent presence of TGF-β1 in asthmatic airways may grad- ually induce airway smooth muscle hypertrophy and hyperplasia. ... TGF-β1 induced phosphorylation of Smad 2/3 and the expression of CTGF mRNA and protein were all blocked by the inhibition of ERK and JNK, but not by the inhibition...

Ngày tải lên: 12/08/2014, 16:20

... terminal differentiation of B cells into antibody-produc- ing cells, upregulation of IL-4-dependent IgE production and stimulation of cytotoxic T-cell differentiation, as well as differentiation of ... Jose PJ, Mitchell J, Belvisi M: Induction of eotaxin expression and release from human airway smooth muscle cells by IL-1beta and TNFalpha: effects of IL-10 and cor...

Ngày tải lên: 12/08/2014, 18:20

... translocation of the dimers to the nucleus is regulated by the binding of several inhibitors of NF-κB (IκB), which both promote the nuclear export of p65 and p50, and maintain p65/p50 and p65/p65 ... and NF-κB2 (p100). Cleavage of the inhibitory domains from p105 and p100 reveals the p50 and p52 “active” versions. The regulation of NF-κB also involves phosphorylati...

Ngày tải lên: 24/08/2014, 11:25

... analysis of different scenarios and boundary conditions which are difficult to model experimentally. These codes allow a better understanding of different hydraulic turbines and flow conditions ... Variation of discharge and binary with two and three pistons of double or single effect out of phase of 90º and 120º 3.2 Positive displacement pumps This engine cons...

Ngày tải lên: 05/09/2013, 15:28