s Membrane proteomic analysis of pancreatic cancer cells docx

... to identify key molecules in the course of hy- poxia-induced apoptotic pathways. Such analysis of trophoblastic cells will, in the near future, yield in- sights into the mechanisms of preeclampsia ... proteins induced by hypoxia in trophoblastic cells so as to clarify the mechanism of hypoxia-induced apoptosis by using the PoweBlot, an antibody-based Western arra...

Ngày tải lên: 31/10/2012, 15:12

... Journal 277 (2010) 4909–4919 ª 2010 The Authors Journal compilation ª 2010 FEBS 4913 Proteomic analysis of dopamine and a- synuclein interplay in a cellular model of Parkinson’s disease pathogenesis Tiziana ... alterations associated with the interplay of cytosolic dopamine and increased a- synuc- lein are still unclear. Catecholaminergic SH-SY5Y human...

Ngày tải lên: 15/02/2014, 01:20

... type II is significantly up-regulated in malig- nant cells [21,22]. Benzamide riboside, tiazofurine and mycophenolic acid are potent inhibitors of this enzy- mic activity and phase II ⁄ III clinical ... expression in MTX-resistant HT29 cells FEBS Journal 272 (2005) 696710 ê 2005 FEBS 705 Modulation of IMPDH2, survivin, topoisomerase I and vimentin increases...

Ngày tải lên: 07/03/2014, 16:20

... 13:R108 http:/ /breast- cancer- research.com/content/13/5/R108 Page 10 of 13 RESEARCH ARTIC LE Open Access Detection of breast cancer cells using targeted magnetic nanoparticles and ultra-sensitive magnetic field ... detection of these particles by using Superconducting Quantum Interference Device (SQUID) sensors [7]. Magnetic relaxometry [6,8-10] for...

Ngày tải lên: 22/03/2014, 17:20

... caspase Tumor protein D52 in prostate cancer R. Ummanni et al. 5712 FEBS Journal 275 (2008) 57035713 ê 2008 The Authors Journal compilation ê 2008 FEBS Altered expression of tumor protein D52 regulates apoptosis ... to as PrLZ and is a member of the tumor protein D52 (TPD52) gene ⁄ protein family and is designated a proto-oncogene [6]. TPD52 is over- e...

Ngày tải lên: 30/03/2014, 02:20

... used a multiplex biomar- ker-measuring technique referred to as proximity ligation assay (PLA) to identify a panel of human plasma biomar- kers for pancreatic cancer [6,7]. PLA was initially ... Fedarko NS, Jain A, Maitra A, Iacobuzio-Donahue C, Rahman A, Hruban RH, Yeo CJ, Goggins M: Evaluation of oste- opontin as biomarker for pancreatic adenocarcinoma. Cancer...

Ngày tải lên: 18/06/2014, 15:20

... al.: Ezrin promotes invasion and metastasis of pancreatic cancer cells. Journal of Translational Medicine 2010 8:61. Submit your next manuscript to BioMed Central and take full advantage of: ã ... analysis of ezrin expression in pancreatic ductal carcinoma samples To study the role of ezrin in pancreatic cancer, we ana- lyzed its expression pattern in 70 PDA...

Ngày tải lên: 18/06/2014, 16:20

... al.: Inhibition of xenotropic murine leukemia virusrelatedvirus by APOBEC3 proteins in PBMCS. J Virol 2011, 85:4888–4897. 18. Rodriguez JJ, Goff SP: Xenotropic murine leukemia virus -related virus ... soon. Downregulation of APOBEC3G by Xenotropic Murine Leukemia -Virus Related Virus (XMRV) in Prostate Cancer Cells Virology Journal 2011, 8:5...

Ngày tải lên: 18/06/2014, 18:20

... 0.05). Application of anti-CXCR4 antibodies had no impact on the migration potential of Caco-2 cells (Figure 4A). CXC receptor-4 gene silencing abrogates migration of colorectal cancer cells To ... rate of colorectal cancer cells after CXCR4 blockage by mRNA silencing and inhibition antibodies CXCR4 blockage by mRNA silencing or anti-CXCR4 anti- bodies migh...

Ngày tải lên: 20/06/2014, 03:20

... the major factors contributing to the origin of ovarian cancer stem cells. Emerging evidence suggests that ovarian cancer stem cells are relatively resistant to conventional cytotoxic chemotherapeutic ... both apoptosis and autophagic cell death in ovarian cancer cells [20]; however the role of genistein in chemo-resistant ovarian cancer cells has not be...

Ngày tải lên: 20/06/2014, 07:20

... ovarian cancer cell lines independently selected for resistance to cisplatin, doxorubicin or paclitaxel, and we use gene expression profiling to identify genes and pathways that may be important ... Microarray analysis of gene expression in drug resistant ovarian cancer cell lines To identify genes and pathways important in the development of dr...

Ngày tải lên: 20/06/2014, 08:20

... proteins were assigned as membrane pro teins in AsPC-1 cells whereas 101 pro- teins were assigned as membrane proteins in BxPC-3 cells. Table 1 lists the “integral to membrane proteins found in A sPC-1 ... over-expressed in AsPC-1 cells, which agrees to the results obtained by the proteomic approach. Discussion Metastasis is a highly organ-specific process, which requires multiple...

Ngày tải lên: 10/08/2014, 05:21

... suggesting that down-regulation of miR-27a might i nhibit the growth of MKN45 cells in vitro and in vivo. Down-regulation of miR-27a might reverse drug resistance of gastric cancer cells As shown ... Clinical Cancer Research 2011, 30:55 http://www.jeccr.com/content/30/1/55 Page 2 of 5 RESEARCH Open Access Down-regulation of miR-27a might inhibit p...

Ngày tải lên: 10/08/2014, 10:21

... Wei et al.: Recombinant immunotoxin anti-c-Met/ PE38KDEL inhibits proliferation and promotes apoptosis of gastric cancer cells. Journal of Experimental & Clinical Cancer Research 2011 30:67. Submit ... target for this type of cancer [3]. The aim of t his study w as to evaluate the effects of recombinant immunotoxin anti-c-Met/PE38KDEL on proliferation...

Ngày tải lên: 10/08/2014, 10:21

... mammalian single cells. Our studies Table 1: The detection of β-actin mRNA from single VNOf90 cells. The number of assays against single cells The number of β-actin positive cases The number of cells ... change of β-actin mRNA levels was also small compared with that of c-fos mRNA levels in single cell analysis as well as in the cell population analysis. Although the...

Ngày tải lên: 11/08/2014, 00:21