roc analysis of interval cancer cases

... ovarian cancer represents 3% of all the new cancer cases in women, but accounts for 5% of all the cancer deaths [1] This discrepancy is due, in part, to the common resistance of ovarian cancer ... Array data processing and analysis was performed using Illumina Bead Studio software Hierarchical clustering analysis of significant genes was done using an algorithm of the JMP 6.0.0 software Microarray ... lack of alternatives for the treatment of drug resistant disease are responsible for a 5-year survival of approximately 30% in ovarian cancer patients with advanced disease Indeed, 90% of the...

Ngày tải lên: 20/06/2014, 08:20

... limited number of predictive variables [20] We therefore propose a very preliminary strategy of comprehensive assessment in line with the evidence of the complex pattern of determinants of depressive ... number of traits of Dependent Personality Disorder (like difficulties to express disagreement, difficulty to things autonomously, fear of being alone and need of support) and several traits of Obsessive-Compulsive ... compliance with the Helsinki Declaration in the context of approval of the local ethical committee for the study Although a follow up of a large cohort of depressed subjects investigated at baseline would...

Ngày tải lên: 08/08/2014, 21:20

... in only three Figure region Aspect of recurrent soft tissue sarcoma in the right axillary Aspect of recurrent soft tissue sarcoma in the right axillary region cases as previously described in patients ... coverage of the defect Postoperative aspect after positioning of the flaps with suffiPostoperative aspect after positioning of the flaps with sufficient coverage of the defect Page of 10 (page ... percent of the patients could substantially be helped by the more than 50 types of therapy [37] Our findings of only moderate acceptance of the prosthetic supply comply with the reports of others...

Ngày tải lên: 09/08/2014, 04:21

... number of peptides matched This may reflect the differential level of a Liu et al Journal of Biomedical Science 2010, 17:74 http://www.jbiomedsci.com/content/17/1/74 Figure Western blot analysis of ... the identification of new tPA receptors in pancreatic cancer cells Proteomics 2006, 6(S1):S36-S41 25 Rathinam R, Alahari S: Important role of integrins in the cancer biology Cancer Metastasis ... RH, Pandey A: A Compendium of Potential Biomarkers of Pancreatic Cancer PLoS Med 2009, 6(4):e1000046 33 Grote T, Logsdon CD: Progress on molecular markers of pancreatic cancer Curr Opin Gastroenterol...

Ngày tải lên: 10/08/2014, 05:21

... Director, Office of Science, Office of Biological and Environmental Research, of the US Department of Energy under Contract No DE-AC02-05CH11231, and by the National Institutes of Health, National Cancer ... the context of breast cancer Traditionally, the site of origin has been one of the primary features with which to classify breast cancers [23-25] The full transcriptional profiles of our cell ... Table Summary of signaling modules Number of rules Key component(s) Summary of key events 1 Pi3k, ErbB4 ErbB4 activation of Pi3k Snca Pyk2 activation of Snca Caml, Rsk Rsk activation of Caml Stat3...

Ngày tải lên: 14/08/2014, 21:20

... the cancer biology through systematic analysis of whole genomes and transcriptomes 1.2 Gastric Cancer Gastric cancer is a leading cause of cancer mortality worldwide, surpassed only by lung cancer ... members of Asia-Pacific Gastric Cancer Genomics Consortium (Prof Hiroyuki Aburatani, University of Tokyo, Japan; Prof David Bowtell, Peter MacCallum Cancer Centre, Australia; Assoc Prof Suet ... treatment of gastric cancer is that very few of the currently utilized classification schemes are strong predictors of clinical behavior Traditional classifications of gastric cancer on the basis of...

Ngày tải lên: 15/09/2015, 17:09

... 1/mm2 RBM3 intensity The number of cases in the multivariate analysis is equal to the number of cases evaluated for RBM3 expression (n = 215) Jonsson et al Journal of Translational Medicine 2011, ... melanoma: An analysis of 215 cases from the Malmö Diet and Cancer Study Journal of Translational Medicine 2011 9:114 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient ... multivariate analysis using backward selection were a p-value of 0.05 decided entry and a p-value of 0.20 was used for removal RBM3 was included in all models irrespective of the backward selection procedure...

Ngày tải lên: 20/06/2014, 04:20

... concepts about interval arithmetic, and we will present the problematic of solving linear systems of interval equations We will then introduce a new formulation of the problem, based on interval parameters ... evaluate the Interval Computations Applied to FEM amount of computations on simple discrete systems, as well as the accuracy of the solutions RESOLUTION OF INTERVAL LINEAR SYSTEMS The interval arithmetic ... 1997 Journal of Mechanical Design, 119, 65–72 Generalizing interval matrix operations for design A D Dimarogonas, 1995 Journal of Sound and Vibration, 183(4), 739–749 Interval analysis of vibrating...

Ngày tải lên: 12/01/2014, 21:45

... Conventional pepscan analysis however, does not allow easy analysis of the contribution of the carbohydrate portion To assess the involvement of carbohydrates in antibody recognition of glycosylated ... fragment of the ligand of the X-ray structure (RCSB PDB entry 1SM3) After small manual corrections, the ligands were docked into the binding site of SM3 using the FLEXIDOCK module of the SYBYL software ... spectra were recorded as a function of the mixing time with intervals of 50, 100, 150, 300, and Ó FEBS 2002 Fig trNOE build-up rates of PDTRP in presence of SM3 plotted as percentage trNOE vs...

Ngày tải lên: 21/02/2014, 15:20

... types of gynecological cancers: cervical cancer, ovarian cancer, and endometrial or uterine cancer As indicated in the Introduction, these cancers account for 90% of all gynecological cancers ... on the three gynecological cancers that account for 90% of all gynecological cancers in California: cervical cancer, ovarian cancer, and endometrial cancer Cervical Cancer Screening Asymptomatic ... a hypothetical cohort of 100,000 women at all levels of risk for ovarian cancer would prevent only 31 cases of ovarian cancer (Nelson et al., 2005) The yield for a cohort of 100,000 at average...

Ngày tải lên: 22/03/2014, 10:20

... inhibits the rDPP IV-binding of rat and human breast cancer cells, mouse melanoma cells (Fig 1A) and several other types of cancer cells (data not shown) However, the failure of 6A3 in recognizing hDPP ... Preventing conformational change of the rDPP IV structure did not avert the inhibitory effect of 6A3 These observations suggest that the inhibitory effect of 6A3 is a result of steric hindrance rather ... lung-metastatic cancer cell adhesion (A) rDPP IV adhesion activities of MDA-MB231, MTF7 and B16F10 (5 · 104 cells per well) in the absence or presence of various concentrations of 6A3 or 0.3 mgÆmL)1...

Ngày tải lên: 29/03/2014, 22:21

... and telomerase levels, an area of extensive study in the field of cancer research We wish to thank the authors of the various chapters of Molecular Analysis of Cancer for their excellent contributions ... Department of Tumour Cell Biology, Institute of Cancer Biology, Danish Cancer Society, Copenhagen, Denmark PER GULDBERG Department of Tumour Cell Biology, Institute of Cancer Biology, Danish Cancer ... Department of Tumour Cell Biology, Institute of Cancer Biology, Danish Cancer Society, Copenhagen, Denmark JESPER ZEUTHEN Department of Tumour Cell Biology, Institute of Cancer Biology, Danish Cancer...

Ngày tải lên: 08/04/2014, 12:51

... question of detecting therapy-related changes in the mass profiles registered for blood samples collected from breast cancer patients SELDI-ToF analysis of the plasma proteome of breast cancer ... responses of patients to therapy but not restoration of the "normal healthy" pattern of the serum profile Conclusions Here we established the high potential of MALDI-ToFbased analyses for detection of ... presence of this peptide did not correlate with the outcome of therapy [31] Similarly, increased levels of two peptides were observed shortly after infusion of docetaxel in the serum of breast cancer...

Ngày tải lên: 18/06/2014, 16:20

... patients with benign conditions Cancer/ testis antigens are by far the most cancer- specific TAA, which are shared by a number of solid tumors including prostate cancer, lung cancer, and so on In normal ... reflect cancer- related inflammation, immunocompetence of the host, and immunogenicity of the endogenously arising cancer [10,11] Even though more and more studies have shown the significance of circulating ... evidence of prostate cancer Table shows the demographic and clinical characteristics of the subjects involved in the comparison of A+PSA with PSA alone Additional file illustrates the distribution of...

Ngày tải lên: 18/06/2014, 19:20

... patients with benign conditions Cancer/ testis antigens are by far the most cancer- specific TAA, which are shared by a number of solid tumors including prostate cancer, lung cancer, and so on In normal ... reflect cancer- related inflammation, immunocompetence of the host, and immunogenicity of the endogenously arising cancer [10,11] Even though more and more studies have shown the significance of circulating ... evidence of prostate cancer Table shows the demographic and clinical characteristics of the subjects involved in the comparison of A+PSA with PSA alone Additional file illustrates the distribution of...

Ngày tải lên: 20/06/2014, 03:20

... report results of a content analysis and psychometric evaluation of this Quality of Life Appraisal Profile, as prelude to a prospective comparison of outcomes of different reconstructive procedures ... idiographic measure of quality of life Analysis of the Construct Validity of the Brief QOL Appraisal Profile A key concept we used to examine the psychometric properties of the Appraisal Profile is construct ... co-morbidities Analysis Plan Our analysis included examination of patient characteristics and quality of life, thematic content coding of responses to the Brief Quality of Life Appraisal Profile, examination...

Ngày tải lên: 20/06/2014, 15:20

Ngày tải lên: 21/06/2014, 05:20

... one of the older group # Data were not available in three young patients to disseminated cancer and 2(12.5%) due to complications of adjuvant therapy In a subset analysis of AJCC stage, of 7(28.6%) ... Page of 11 Chan et al World Journal of Surgical Oncology 2010, 8:82 http://www.wjso.com/content/8/1/82 Page of 11 Figure Effect of neoadjuvant therapy for rectal cancer on overall survival cancers ... -Undertook all of the statistical analysis and contributed to several drafts of the paper RID Helped in data collection and tabulation and provision of data for survival analysis RW - Collection of data,...

Ngày tải lên: 09/08/2014, 03:22

... Frequency of lymph nodal metastasis of pancreatic cancer Page of 13 treatment of pancreatic cancer has not been addressed With more effective chemotherapy for systemic treatment of pancreatic cancer, ... 13 Figure Flowchart of studies to final number of eligible studies Table Classification of regional lymph nodes of the pancreas No of Study Studies Year Location of Tumors No of Patients LN Positivity ... rates of pancreatic head cancer; cancer of body/tail of pancreas in only Sun et al Radiation Oncology 2010, 5:28 http://www.ro-journal.com/content/5/1/28 Page of 13 Figure JPS Classification of...

Ngày tải lên: 09/08/2014, 08:23

... occurred in 45% and 37% of patients with MLD of more than 15 Gy and NTCP of 50% or more, respectively, whereas it occurred in 0% of patients with a MLD of 10 Gy or less and NTCP of less than 17%, respectively ... Foundation of China (30870738) We thank Drs Zhongxing Liao and Joe Y Chang of the University of Texas M D Anderson Cancer Center of Texas, USA for reviewing the manuscript Author Details Department of ... file contains a number of important clinical parameters predictive of risk of RP as reported in the literature Additional file Dosimetric parameters predictive of risk of RP as reported in the...

Ngày tải lên: 09/08/2014, 08:23