adenoviruses basic biology to gene therapy

... “You Adenoviruses: Basic Biology to Gene Therapy 2 do not have to wait until then,” and he telephoned Dr. Rowe and told him to send me the virus—can you imagine that happening at this time in history? Dr. ... 1-57059-584-4(alk. paper) 1. Adenoviruses. 2. Genetic vectors. 3. Gene therapy. I. Seth, Prem, II. Series. [DNLM: 1. Adenoviridae. 2. Gene Therapy methods. 3. Gene...

Ngày tải lên: 10/04/2014, 10:58

... orders@intechopen.com Tissue Regeneration – From Basic Biology to Clinical Application, Edited by Jamie Davies p. cm. ISBN 978-953-51-0387-5 Tissue Regeneration – From Basic Biology to Clinical Application ... transition from inflammatory to the remodelling phase in tissue repair. Advanced laser systems allow to apply more complex treatment protocols, to try to...

Ngày tải lên: 30/03/2014, 22:20

... issues related to human germline gene therapy. 2. Criteria for Assessing Applicability to Human Germline Gene Therapy An ideal gene transfer system in the context of human germline gene therapy would ... Warburton PE, Farr CJ. Chromosome engineering: prospects for gene therapy. Gene Ther. 2002; 9(11):713-718. 85. Lipps HJ, Jenke ACW, Nehlsen K, et al. Chromosome-base...

Ngày tải lên: 03/11/2012, 10:01

... functional genomic research. It is therefore interesting to * Author to whom correspondence should be addressed. MicroRNAs: From Basic Science to Disease Biology, ed. Krishnarao Appasani. Published by Cambridge ... Preiss Molecular Genetics Program Victor Chang Cardiac Research Institute 384 Victoria Street, Darlinghurst Sidney, NSW 2010, Australia Liang-Hu Qu Biotechnology Research...

Ngày tải lên: 06/03/2014, 09:21

... 1998a). Growth factors Vascular growth factors are potent chemoattractants and mitogens. Factors such as platelet-derived growth factor (PDGF) and basic Wbroblast growth factor (bFGF) are thought to play ... estimated to bind to proteins or to be taken up into stores (Kamishima and McCarron, 1996). Despite this, opening of Ca 2+ channels causes [Ca 2+ ] i to rise to micromolar l...

Ngày tải lên: 22/03/2014, 20:21

... INTRODUCTION Gene therapy provides a novel method to repair damaged bone by using bone morphogenetic protein (BMP). BMP gene vectors can be divided into DNA, viral, and cell vectors [10, 19]. ... appear to tolerate first- generation adenoviral vectors, and exposure to adenoviral antigens still elicits the generation of a robust immune response [7]. The overexpression of self...

Ngày tải lên: 31/10/2012, 17:08

... các bước sau: - Lựa chọn vector liệu pháp thích hợp. - Tách và tạo vector tái tổ hợp mang gen liệu pháp, thường thì tạo vector virus để chuyển hiệu quả. - Đưa vector tái tổ hợp mang gen liệu ... vector đã tách gen này cho phép mang gen dài 8kb. Để thiết kế vector andenovirus phải cắt bỏ gen E1 rồi thay thế bằng phức hợp promotor-gen liệu pháp và gây bất hoạt hoặc cắt bỏ gen E3. Vect...

Ngày tải lên: 06/09/2013, 22:49