from basic biology to cell based applications

... in the cell body MAP2 function is 20 Tissue Regeneration – From Basic Biology to Clinical Application not required when the cell disassembles microtubules in the cell body to give rise to the ... of Hz, to 12 h/day cells toward (IVD) and stem cells loading on IVD and hydrostatic pressure “discogenic” stem cells 0.1 to 10 Mpa, 0.25 to phenotype Hz 25 The Role of Physical Factors in Cell ... forces are relevant to healing because many cell types sense and respond to mechanical forces using sensory systems in their cell- cell junctions, cell- matrix junctions and cytoskeleton The sensing...

Ngày tải lên: 30/03/2014, 22:20

... in the cell body MAP2 function is 20 Tissue Regeneration – From Basic Biology to Clinical Application not required when the cell disassembles microtubules in the cell body to give rise to the ... of Hz, to 12 h/day cells toward (IVD) and stem cells loading on IVD and hydrostatic pressure “discogenic” stem cells 0.1 to 10 Mpa, 0.25 to phenotype Hz 25 The Role of Physical Factors in Cell ... forces are relevant to healing because many cell types sense and respond to mechanical forces using sensory systems in their cell- cell junctions, cell- matrix junctions and cytoskeleton The sensing...

Ngày tải lên: 27/06/2014, 09:20

... research He is the Editor of RNA Interference: From Basic Science to Drug Development (2005) To my wife Shyamala for her 25 years companionship MicroRNAs FROM BASIC SCIENCE TO DISEASE BIOLOGY Edited ... in any organism to date In this book I intend to bring the various aspects of microRNA research together, including the biology, applications, their role in stem cell and disease biology As the ... incorporated into an Argonaute containing silencing complex (RISC) (Du and Zamore, 2005) From this * Author to whom correspondence should be addressed MicroRNAs: From Basic Science to Disease Biology, ...

Ngày tải lên: 06/03/2014, 09:21

... 2007-1 Progestins and the Mammary Gland From Basic Science to Clinical Applications O Conneely, C Otto Editors With 43 Figures 123 Series Editors: G Stock and M Lessl Library of Congress Control ... breast cells grow “mammospheres” of which 27% of the total sphere cells were found to be within the SP Additionally, from fresh breast digests, only SP cells and not non-SP cells were able to form ... results to those observed in the mouse The percentage of cells which were able to efflux the dye and form the SP varied from 0.2% to 1% to 5% (Alvi et al 2003; Clarke et al 2005; Clayton et al...

Ngày tải lên: 15/03/2014, 09:20

... integrins Cell -to- cell and extracellular matrix -to- cell interactions profoundly aVect smooth muscle cell behaviour (Hughes and Schachter, 1994; Braun et al., 1999) Activation of receptors for extracellular ... seen in cultured cells These proteins are involved in attaching the cytoskeleton to other transmembraneous proteins which couple the cells to other cells (cadherins) or to extracellular matrix ... and myosin are removed from the cell a cytoskeletal network of Table 1.2 Components of the contractile apparatus and cytoskeleton in smooth muscle Cytoskeleton Membrane skeleton Contractile apparatus...

Ngày tải lên: 22/03/2014, 20:21

... among persons ages 12 to 65 in 1998 and 2005 Use of amphetamine/ MA by males in Tijuana increased from 0.7% to 1.6%, and use by males in Juarez increased from 0.1% to 2.0% (Villatoro et al., 2006) ... domestic MA purchases from $152.39 to $280.06, and a 26% decrease in purity from 57% to 42% between January and December 2007 (Drug Enforcement Administration [DEA], 2008) Based on the changing ... their sources as from friend or relative for free” (53.6%), “bought from a friend or relative” (21.4%), or “bought from dealer or stranger” (21.1%) (SAMHSA, 2007c) From 2002 to 2005, Native Americans...

Ngày tải lên: 06/03/2014, 09:21

... TTOA01_vol1 3/9/07 10:46 AM Page i TEXTBOOK OF Hepatology From Basic Science to Clinical Practice TTOA01_vol1 3/9/07 10:46 AM Page ii Textbook of Hepatology Third Edition ... highlighted in the text TTOA01_vol1 3/12/07 4:44 PM Page iii TEXTBOOK OF Hepatology From Basic Science to Clinical Practice THIRD EDITION SECTIONS 110 AND INDEX EDITORS ASSOCIATE EDITORS Juan Rodộs MD ... Consultant Hepatologist Beth Israel Deaconess Medical Center Boston, MA, USA Nazia Selzner MD PhD Transplant Hepatology Fellow Multiorgan Transplant Program Toronto General Hospital Toronto, ON, Canada...

Ngày tải lên: 06/03/2014, 09:21

... leukemia cells promotes cell division in these cells Both siRNA and a lentivirus vector containing shRNA have been shown to reduce the levels of p210 protein in cell lines and thereby inhibit cell ... moloney murine leukemia virus -based retroviral vectors for efficient delivery of siRNAs into the mammalian cells Lentiviral -based siRNA vectors will have the ability to generate transgenic animals ... used within the cell and molecular biology communities as a tool to aid understanding of gene expression and regulation In addition, scientists have begun to take an RNomics approach to understanding...

Ngày tải lên: 06/03/2014, 09:21

... Adenoviruses: Basic Biology to Gene Therapy, edited by Prem Seth ©1999 R.G Landes Company 2 Adenoviruses: Basic Biology to Gene Therapy not have to wait until then,” and he telephoned Dr Rowe and told ... into Cells 31 Prem Seth Binding of Adenovirus to the Cell Receptor, and its Entry into the Endosomes 31 Adenovirus-Mediated Lysis of Endosome Membrane: Role of Low pH and Penton ... leaving the Army Dr Robert Huebner came to Western Reserve to present a seminar and came to my laboratory to visit He told me of Wally Rowe’s viral isolation from adenoid cultures, and immediately...

Ngày tải lên: 10/04/2014, 10:58

... Workshops”, and the NATO Science Series collects together the results of these meetings The meetings are co-organized by scientists from NATO countries and scientists from NATO’s Partner countries ... permission from http://www.photon.t.utokyo.ac.jp/~maruyama/agallery/agallery.html) A SWCNT is constituted from a one atomic layer thick sheet with graphitelike structure (graphene sheet) rolled into ... added to Fe/Y catalysts on the yield of nanotubes and their properties We chose Fe instead of Ni because it is much easier to remove it from the arc product Our primary aim is to find satisfactorily...

Ngày tải lên: 04/06/2014, 15:13

... TNF receptor-associated factor 2, TRAIL – TNF-related apoptosis inducing ligand Bladder Cancer Biology 13 The export of cytochrome c into the cytoplasm and its binding to APAF1 (apoptotic peptidase ... the anti-apoptotic factor BCL2 and the pro-apoptotic factor BAX seems to act as a cellular rheostat that might be predictive for a cell s response toward life or death after an apoptotic stimulus ... Biology 15 leading to uncontrolled cell growth and proliferation [Fig.4] In principle, peptide growth factors bind to their corresponding growth factor receptors on the cell surface leading to...

Ngày tải lên: 27/06/2014, 13:20

... of primary beta cells Most importantly, these cells can reverse hyperglycemia when grafted into streptozotocin-treated mice Relative to their progenitor E-RoSH cells, ERoSHK cells also exhibit ... differentiation of pluripotent stem cells to 10 Embryonic Stem Cells – Basic Biology to Bioengineering therapeutically useful cell types , the two human ESC-derived cell types ready for testing in ... vitro cell studies (e.g neural induction of EC cells by RA) These factors may or may not play a role in development 12 Embryonic Stem Cells – Basic Biology to Bioengineering extra-embryonic factors...

Ngày tải lên: 28/06/2014, 05:20

... activated in response to virtually all mitogenic factors Second, several studies have reported that the mitogenic response to growth factors is correlated with their ability to induce sustained ... mediated by growth factor binding to receptor tyrosine kinases See text for details GF, growth factor; RTK, receptor tyrosine kinase distinct MAP kinase pathways (Fig 2A) Aside from MEK1/MEK2, the ... U0126 have proven to be invaluable academic research tools to investigate the role of the ERK1/2 MAP kinase pathway in normal cell physiology and disease To date, eleven MEK1/2 inhibitors have been...

Ngày tải lên: 10/08/2014, 22:20

... roadmap for transforming from functional to process based structure Transitioning an organization from functional structure to process -based structure is not easy The company has to choice the right ... will enable the trends to customer-oriented organization; this is the key factor for quality improvement and gaining customer satisfaction - Processes – based will help sTech to better use resources ... from three objectives: Improve employee satisfaction and leverage the IT based management - To increase sales & marketing efficiency, Serenco has to leverage IT based management 27 Planning Based...

Ngày tải lên: 25/11/2016, 09:50

... A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics Pier Andrea Borea Editor A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics Editor Pier Andrea Borea ... both basic science and the relevant applications and provide an authoritative account of the current status of the field They have enabled my goal as editor to make “A3 Adenosine Receptors from Cell ... least, I wish to thank the members of my Research Group for their scientific work in the field of A3 adenosine receptors The first edition of “A3 Adenosine Receptors from Cell Biology to Pharmacology...

Ngày tải lên: 22/03/2014, 23:20

... leukaemia From systems to networks biology Talks related to networks biology covered a large portion of the meeting Among many different types of biological networks discussed were gene regulatory ... their regulatory elements The development of techniques to detect longdistance interactions was the topic of J Dekker’s talk from the University of Massachusetts Medical School (Boston, MA, USA) ... regulatory elements that are active only in a particular cellular state, developmental stage or cell type Functional genomics approaches to diagnosis of diseases One of the goals of systems biology...

Ngày tải lên: 30/03/2014, 09:20

... Genome Biology 2009, http://genomebiology.com/2009/10/3/305 Although great insight into many biological processes has come from cell- based screens, complex developmental ... cryo-electron tomography to generate three-dimensional topological structures of macromolecules He then identifies different macromolecular complexes in fixed cells, based on a library of topological ... of up to 50 different antibodies Structural biology has greatly expanded in the past decade due to the establishment of several consortia Cheryl Arrowsmith (Ontario Cancer Institute, Toronto, Canada)...

Ngày tải lên: 14/08/2014, 21:20

... around TSSs Genome Biology 2009, 10:217 http://genomebiology.com/2009/10/4/217 Genome Biology 2009, could be different from the isoforms annotated so far It will be interesting to see how many of ... factor binding sites were identified and this information was linked to changes in expression levels of the downstream transcript to infer the activity of the relevant transcription factors From ... of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs Cell 2004, 116:499-509 Martone R, Euskirchen G, Bertone P, Hartman S,...

Ngày tải lên: 14/08/2014, 21:20

... of cell attachment, when cell- cell contacts get tighter [54] Put together, these readings make it possible to derive, in real-time, cell viability, growth, and cell cycle stage Similarly to the ... examine cells • Simple and fast • Does not require to resuspend cells • Real-time monitoring of cell viability • Provides cell cycle stage information • Does not require to resuspend cells • ... be used for cell culture Li et al [72] show that such a scaffold is able to sustain the growth of neural stem cells, with potential applications in tissue engineering, or basic cell biology experiments...

Ngày tải lên: 09/09/2015, 08:12

... able to build an array of QCM, and measuring both forces and viscosity would be a interesting new tool to study cell dynamics This approach was not pursed further, as it deviated too much from ... Cells on device vs cells in the same dish As a further experiment, I checked if the device is sensitive to cells directly in contact with the graphene surface, or if it is only sensitive to cells ... between the top and bottom electrodes is changed due to Shear forces, as well as bulk forces This approach, however, has the disadvantages of requiring precise 57 alignment of top and bottom electrodes...

Ngày tải lên: 09/09/2015, 08:12