... analysis offive clinical trials in which atomoxetine was generally shown to be effective in improving certain aspects of HRQoL in 794 children and adolescents with ADHD [31] In addition, in our ... performed in a 2-sided manner in an exploratory sense without adjustment for multiple testing The evaluations were performed according to the intention -to- treat (ITT) principle All enrolled patients who ... at baseline to 19.1 ± 4.0 at study end (p < 0.0001) according to parents’ ratings, and from 18.4 ± 3.7 to 20.4 ± 3.6 (p < 0.0001) according to patients’ ratings (Figure 3) Mean baseline ILC LQ0-28...
... La Chaine de Those of us currently involved in paediatric cardiac care in Africa L’Espoir in surgical missions to Mozambique, in the under- need to work together, coordinating our efforts to become ... begins, complex cases being flown to up in most of the major centres in South Africa, and also a few in mentor institutions Africa, including in Egypt and Uganda However, while this phase of ... sending expensive missions to building local expertise They are currently working in various centres in Africa, including at our unit in Cape Town, to support, train and develop local personnel in...
... specific to the incidence include sources of transplantation and the time point of assessment RiskFactors for Chronic GVHD The main purpose of this article is to report the evidence ofriskfactors ... tice guidelines This review also provides insight into risk factors. This is important to provide nurses and research ers with an understanding of how to assess chronic GVHD risk No instruments ... Immunological Nursing Support Care Educate children and parents to prevent further skin injury; develop strategies to manage symptoms, including itching and dry skin Discuss ways to manage relief of dry...
... (gait, Gross Motor Function Measure, and clinical examination) using botulinum toxin injections have been reported, but evidence is limited regarding the effect of botulinum toxin treatment on ... decreased internal hip rotation at initial contact, toe-off, and mid-swing inchildrenwho had undergone multilevel botulinum A treatments Botulinum injections were started at a young age and combined ... review of symptoms, including the presence of pain, decreased sitting tolerance, autonomic dysreflexia, and skin ulcers, is critical [130,131] A hip 180 DRISCOLL & SKINNER physical examination...
... respiratory symptoms) Encourage the patient to drink, monitor intake and output Initiate an IV (if febrile, dehydrated or in moderate to severe pain) For mild to moderate pain give: • Acetaminophen ... Monitoring Children receiving IV morphine must be carefully monitored for signs of opioid toxicity which may include: hypotension, bradycardia, drowsiness, coma, pinpoint pupils, cold clammy skin, ... Management of Sickle Cell DiseaseinChildren Page 14 of 15 Appendix Monitoring Guidelines for Patients Receiving Intravenous Opioid Analgesia: Analgesia Continuous Opioid Infusion Intermittent...
... the problem of chronic dental disease and the factors that contribute to low use of dental care by lowincome populations, including childrenin Medicaid.2 Low-income children eligible under a state ... also include data for childrenin SCHIP, which we estimate to be about 15 percent of the total At the same time, indicators of receipt of dental care, including the proportion ofchildrenwho ... indicators of the oral health status ofchildrenin Medicaid, specifically, the rate of dental disease and their receipt of dental care, and changes in these indicators over time.3 To determine...
... protein57 as predictive factors Although these studies included cases of meningococcal meningitis, they were the minority of total cases In a study analysing a subgroup of 60 cases of meningococcal ... preventing meningococcal disease occurring in the contact groups? consider timing and dose a Rifampicin b Ciproflaxin c Ceftriaxone 11 Does administration of meningococcal vaccination to cases of invasive ... procalcitonin assay as an indicator of severity and a predictor of outcome research to identify the normal compartment pressures inchildren evaluation of the capability of cefotaxime to eliminate...
... suggestive of CD without increasing the riskof misclassification Preconditions are • • • • high quality serology including EMA taking quantitative antibody levels into account HLA typing full information ... serology) Risk- benefit ratio has changed: risk and cost of invasive procedure (OEGD, histological work-up) versus riskof false positive diagnosis Asymptomatic person at genetic risk for CD Explain ... Agenda • • • • Change in clinical paradigm Definitions of coeliac disease New diagnostic guidelines Algorithms Interlaken ESPGHAN criteria (1979) Small intestinal biopsy: villous atrophy...
... Cushing’s syndrome inchildren and adolescents: current diagnostic and therapeutic strategies J Endocrinol Invest 2002; 25:181−94 Leinung MC, Zimmerman D Cushing’s diseaseinchildren Endocrinol ... Relative contributions of inferior petrosal sinus sampling and pituitary imaging in the investigation ofchildren and adolescents with ACTH-dependent Cushing’s syndrome J Clin Endocrinol Metab 2001;86:5711−4 ... of chronic ACTH stimulation.20 Our experience demonstrated that hypokalemia may not be a rare finding inchildren with Cushing’s disease The diagnosis of Cushing’s disease is based on the clinical...
... Serum total bilirubin, albumin and prothrombin time were essentially within the normal range in all patients Positive autoantibodies in low titres were found in 20% of patients including ANA in ... inflammatory infiltrate, and ballooning, the presence of Mallory hyaline, and stage of fibrosis were graded according to the scoring system proposed by Kleiner et al.31 Statistical analysis Continuous ... and SMA in 10% of patients Liver histology The main liver biopsy features are summarised in table Some degree of fibrosis was present in 59% ofchildren including mild fibrosis (stage 1–2) in 11,...
... to the total attributableburden is shown in Fig The burdenofdisease attributed to the use of household solid fuels is dominated by the burden caused by ALRIs inchildrenunder years of age, ... scarce In order to avoid possible overestimation of the burdenofdiseaseattributableto indoor smoke, PAFs for lung cancer and COPD caused by exposure to indoor smoke were applied todiseaseburden ... the effects of indoor smoke on the riskof pneumonia in children, the introduction of a well-operating chimney stove reduced exposure to indoor smoke by about half As a result the riskof serious...
... previously found to be associated with fewer SCD symptoms [30], interventions to increase autonomy could possibly lead to a decrease in SCD symptomatology in this age group Interestingly, adolescents ... measurement of HRQoL, encompassing all three components ofchildren s well-being, is still in its infancy inchildren with SCD [11] For example, compared to over 400 studies on HRQoL inchildren ... differences between children with SCD and healthy siblings, by dividing the difference in mean score between children with SCD and healthy siblings by the pooled SD of both groups According to Cohen [21],...
... reduction in the burdenofdisease (DALYs averted) as a result of the intervention Following the Global BurdenofDisease methodology [32-34], the burdenofdisease for an individual of sex s dying ... number of individuals seeking treatment and translating the resulting health benefits into DALYs averted A similar procedure was applied to preventive interventions involving first determining the ... that as much as one quarter of the total burdenofdisease could be averted by focusing on a few interventions at a level of total costs corresponding to ten percent of the current, national expenditure...
... beginning of each interval was calculated by subtracting from the number of people in the previous interval the number of deaths occurring in that interval The number of person-years in each interval ... proportion of the total CHSS spending for cerebrovascular diseases in the United Kingdom The total UK CHSS costs for cerebrovascular diseases were taken from the Department of Health BurdenofDisease ... sensitive total aSAH-related costs (including non-healthcare costs) were to changes in key factors holding everything else constant Overall, changes in the proportion of all cerebrovascular diseases...
... commencing with botulinum toxin injections to the gastrosoleus for the younger child with a purely dynamic problem It progresses through botulinum toxin plus casting, serial casting or toxin plus ... trial In order to reduce the riskto individual children and to gain the maximum information, we admitted each child to hospital for to days, during which objective measurements including gait ... injection of botulinum toxin in the management of dynamic equinus inchildren with cerebral palsy They concluded that both interventions were effective but that the effects of botulinum toxin lasted...
... specific environmentalrisk factor and disease or diseaserisk Deaths attributabletoenvironmental factors, bydisease and mortality stratum, for WHO regions in2002Burdenofdisease (in DALYs) attributable ... people, byWHO subregion (2002) Environmentaldiseaseburdenin deaths per 100 000 people, byWHO subregion (2002) Main diseases contributing to the environmentalburdenof disease, for the total ... health of 26 riskfactors The six environmental CRA riskfactors included in our analysis are summarized in Table TABLE ENVIRONMENTALRISKFACTORS AND RELATED DISEASES INCLUDED IN THE CRA a Risk factors...
... Rodgers, Colin D Mathers, and Christopher J L Murray BurdenofDiseaseAttributabletoRiskFactorsRisk Factor Selection BurdenofDiseaseAttributableto Individual RiskFactors Joint Effects of Multiple ... and Burdenof Disease, by Age and Sex Joint Contributions (PAFs) of the Leading RiskFactorsto Mortality and Burdenof Disease, byRegion Individual and Joint Contributions ofRiskFactorsto ... ofRiskFactorsto Mortality and BurdenofDisease from Cardiovascular Diseases Individual and Joint Contributions ofRiskFactorsto Mortality and BurdenofDisease from Major Diseases of Children...
... and symptoms Occasional abdominal pain, difficulty gaining weight and height Prior history of anemia Difficulty gaining weight and height Prior history of anemia Frequent abdominal pain, difficulty ... relation to complaints, 58/78 (74%) of the mothers said their children had difficulty gaining weight, 67/78 (86%) reported failure to thrive and 47/78 (60%) of the children had a history of anemia ... the small intestine, causing an inadequate absorption of nutrients The disease has a varied spectrum of presentations, ranging from the classic form (chronic diarrhea, abdominal pain and distension,...
... Bush A, editores Kendig’s disorders of the respiratory tract inchildren Philadelphia: Saunders; 2006 p 359-67 12 Fan LL, Kozinetz CA Factors influencing survival inchildren with chronic interstitial ... Epidemiological research into interstitial lung diseases in tion, including on prognosis, with the ability to assess the children is made difficult by the scarcity of information degree of fibrosis Nevertheless, ... routine procedure for assessing cellularity, since it requires childrento be sedated and increases the potential riskof aggravating hypoxemia It was indicated when there was a suspicion of diseases...
... history Work limitations, including limitations in the amount or kind of work a person can as well as inability to work, were reported by 37% and 29% of middle-aged men who were diagnosed within ... and screening • Behavioral Risk Factor Surveillance System (BRFSS), 2002: Prevalence estimates of screening tests for selected cancers • NHIS, 2003: Prevalence of behavioral riskfactorsTo address ... local, regional and distant five-year relative survival for pancreatic cancer ranges from 15% to 8% to 2% in men, and 19% to 7% to 2% in women 11 The Burdenof Cancer in American Adults Living with...