what regions of theface neck can be reconstructed with this flap
Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... series of GST-fused deletions of the CD2-1 region (Fig 3E) and examined the interactions between bacterially expressed proteins of these subregions (Fig S1C) and 1654 Fig Of all members of the ... cotransfection with EGFP in hippocampal neurons (Fig 7) When compared with neurons transfected with wild-type v-KIND, which decreased the number of dendrites, neurons transfected with the L474A ... activity of v-KIND induces the phosphorylation of MAP2 by JNK1 and ⁄ or ERK via the activation of the Ras–Raf–MAP kinase pathway [12] These results appear to be in agreement with those of previous...
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Báo cáo khoa học: Proteolytic activation and function of the cytokine Spatzle in the innate immune response of a lepidopteran insect, Manduca sexta ppt
... cystine-knot domains ¨ Fig S3 Analysis of the relative abundance of two Spatzle isoforms in M sexta ¨ This supplementary material can be found in the online version of this article Please note: As a ... by 24 h after injection of larvae with a Gram-positive bacterium or b-1,3-glucan (a component of fungal cell walls), but no significant change was observed after injection of a Gram-negative bacterium ... responses has been identified in a beetle, Tenebrio molitor The Te molitor clip-domain SPE has been demonstrated to be activated by a proteinase cascade stimulated by peptidoglycan or b-1,3-glucan, and...
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Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf
... core of the C-domain, together with Arg192 and Arg203 of the M-domain [21], form the interface with eRF3 However, all of the mobile regions that could not be seen in the crystal structure of human ... in the closed conformer This can be explained by increased mobility of this region in the open conformer, and partially by faster exchange of the amide proton of Gly337 with water The second FEBS ... C-terminal domain of human eRF1 in solution Table S2 Impact of mutations of human eRF1 on the GTPase activity of eRF3 in its ternary complex with the ribosome This supplementary material can be found...
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Báo cáo khoa học: Structure and function of the 3-carboxy-cis,cis-muconate lactonizing enzyme from the protocatechuate degradative pathway of Agrobacterium radiobacter S2 pdf
... sequences of the CMLE1s from members of the Rhizobiales, such as ArCMLE1 and AtCMLE1, are significantly shorter than the isofunctional enzymes from other bacteria (Fig 2) Expression of ArCMLE1 ... catalysis The alignment of the small CMLEs from different members of the Rhizobiales with these sequences demonstrated that in A radiobacter S2 (and the other member of the Rhizobiales), the ... Wavelength (A) Number of observations Number of unique reflections Space group ˚ Unit-cell parameters (A,°) Completeness (%) Rmergea (%) I ⁄ r(I) R-factorb (%) Rfreec (%) Number of atoms per asymmetric...
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structure and function of the arabic verb
... own copy of this or any of Taylor & Francis or Routledge’s collection of thousands of eBooks please go to www.eBookstore.tandf.co.uk.” © 2008 Maher Bahloul All rights reserved No part of this book ... certainly present within the Arabic clause, the value of this category is less likely to take part in the values of the invariant of both the Perfect and the Imperfect” (p 185) There can be little doubt ... during the Spring of 2006 at the University of Utah as a Visiting Scholar I thus had access to one of the most resourceful libraries Since the origin of this book can easily be traced to my PhD...
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ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 1 pps
... activation of structures of the limbic system, which can explain why patients with tinnitus often present with symptoms of affective disorders such as fear and depression The role of the non-classical ... individuals but with age the cartilaginous part often changes shape and attains an oval shape In addition to changing its shape with age, the lumen of the ear canal often becomes smaller with age, ... Impairment of Sound Conduction in the Cochlea 213 3.4 Accuracy of Measurements of Conductive Hearing Loss 213 3.5 Implications of Impairment of Conduction of Sound to the Cochlea 214 Pathologies of the...
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ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 2 ppsx
... longer be described by a single number because its impedance becomes a complex quantity that requires two numbers to be described A complex quantity, such as an impedance, Z, can be described by ... the American Institute of Physics) 28 Section I into estimates of sound transmission in humans will be discussed below Some of the earliest studies of the frequency transfer function of the middle ... action as a single number and the transformer ratio of the middle ear must be described by a function of frequency, namely, its transfer function Estimates of the gain of the middle ear by different...
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ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 4 potx
... A plot of the threshold of an auditory nerve fiber as a function of the frequency of a tone is known as a frequency threshold curve, or tuning curve Tuning curves of cells of the nuclei of the ... description of the spectral properties of sounds The spectrum of a sound can be completely described by a real and an imaginary number for each frequency The power spectrum is the sum of the squared ... large number of nerve fibers, the result is a family of tuning curves that covers the entire range of hearing of the particular animal that is studied (Fig 6.3) The range of hearing of different...
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ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 6 pot
... traditionally labeled with roman numerals The first five of these peaks of the human ABR except peak IV can usually be discerned in individuals with normal hearing The labeling of the vertex positive ... amplitude of one of the two peaks may increase because the N1 peak of one response coincides with the N2 peak of the previous response When the rate of the stimulus presentation is increased beyond ... potentials are labeled with the letter P and N respectively, followed by a number that gives the normal value of the latency of the respective component One of the consequences of only labeling the...
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ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 7 pot
... removal of the cerumen The ear canal in frequent swimmers often narrows because of formation of new bone (exostosis) This makes it easier for the accumulation of cerumen to obstruct the ear canal ... distribution of fiber diameters of auditory nerve fibers widens with age [309] (see also Chapter 5) This causes a wider distribution of conduction velocities of auditory nerve fibers and thus ... been the topic of discussion how and if middle-ear infections should be treated, but there is little doubt about the benefit from treating the hearing deficit This can be done independently of...
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ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 8 docx
... effectiveness of MRI scanning are subjected to misinterpretations This is because MRIs are used both as a comparison between other methods and as the definitive proof of the presence of a tumor MRI scans ... hemorrhage within the labyrinth, as might be expected with a viral cochleitis The authors of this study concluded that the most likely cause of SSNHL may be a pathologic activation of cellular ... fibers have later been interpreted to be caused by impairment of the active function of outer hair cells (see Chapter 3) Tuning of single auditory nerve fibers in animals that were treated with...
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ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 9 pdf
... stimulus strength of a sound causes an increasing number of nerve fibers to become activated because of the widening of the segment of the basilar membrane that cause activation of nerve fibers (see ... caused by expression of neural plasticity are often labeled as “functional” because no morphological correlates can be detected The label “functional” has often been used to describe psychiatric disorders, ... location of the physiological abnormality of recruitment of loudness is the ear, most often the cochlea, but absence of function of the acoustic middle-ear reflex can also cause an abnormal growth of...
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Báo cáo y học: "Relationship between the tissue-specificity of mouse gene expression and the evolutionary origin and function of the protein" ppsx
... sets (out of all 12,488 probe sets) in a tissue Fraction of expressed probe sets (out of all 12,488 probe sets) in a tissue (black) The grey bars represent the fraction of expressed probe sets ... unless one of the ortholog pairs was annotated as 'best reciprocal hit' (BRH) The ratio of Ka (the number of non-synonymous substitutions per non-synonymous site) to Ks (the number of synonymous ... equal bins of similar recent rates of evolution (Ka/Ks values) and then shuffling the phyletic ages within each group, sample sets of data can be created which have no connection between phyletic...
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EXPRESSION AND FUNCTION OF THE PRL FAMILY OF PROTEIN TYROSINE PHOSPHATASE
... consisted of (a) omission of the oligonucleotide probes from the hybridization mixture, (b) substitution of the specific antisense probe with an equivalent concentration of labeled sense probe, (c) ... evaluation of the two sections The percentage of positive cells was estimated as the number of stained cells, per total number of cells counted The localization of staining within the cells of each ... evaluation of the two sections Percentage of positive cells was estimated as the number of stained cells per total xxiv 1404 number of cells counted To confirm reproducibility of the analysis, 25% of...
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Regulation and function of the novel candidate tumor suppressor gene dlec1 in the HCT116 colorectal cancer cell line
... type, this pathway can transmit signals, which result in the prevention or induction of apoptosis or cell cycle progression Abnormal activation of this pathway occurs in a number of types of cancers, ... has been estimated that over 12 million people have been diagnosed with cancer last year, according to the World Cancer Report 2008 by the World Health Organization (World Cancer Report, 2003) Cancer ... observed significant difference between cells transfected with Gal4 vector control and those transfected with Gal4-DLEC1 plasmid (Figure 5.1.9), in terms of 31 RESULTS number and size of the colonies...
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Tài liệu Body Size: The Structure and Function of Aquatic Ecosystems pptx
... of the same body size can differ in lifespan by at least an order of magnitude If the first-order effect of temperature had not been removed, then there would have been even more variation, with ... scales as MÀ3/4 This is what would be expected if populations of a guild or trophic level had equal rates of resource supply, R, because the steady-state population density, N, should be proportional ... storage of elements in ecosystems The total biomass per unit area, W, is simply the sum of the body mass of all individuals For organisms of similar size, it can be estimated by taking the product of...
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Tài liệu Báo cáo khoa học: Helix mobility and recognition function of the rat thyroid transcription factor 1 homeodomain – hints from 15N-NMR relaxation studies pdf
... S2) This value can be reliably considered to be the average NOE over the structured core of the investigated TTF-1 HD molecule Backbone dynamics of the rat TTF-1 homeodomain Fig Bar graphs of ... artefact of the optimization However, a decreasing trend of the internal se coupled with a similar behavior of the generalized order parameter unequivocally emerges on examination of segment 50–55 of ... corresponding counterparts of helix I This result can be rationalized on a structural basis Helix II, in fact, should be the least stable among the TTF-1 HD helices, because of its incomplete hydrogen...
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Tài liệu Báo cáo khoa học: Expression and function of Noxo1c, an alternative splicing form of the NADPH oxidase organizer 1 doc
... localization of Noxo1b after treatment of the cells with PMA, as the cells became rounded without detaching from coverslips To biochemically assess the localization of Noxo1s after treatment with PMA, ... associated with the membrane fraction (Fig 4B) As the extent of the membrane localization of Noxo1 correlated well with that of the superoxide-producing activity of Nox1 (Fig 4C), a weaker activity of ... SH3 domain of Noxo1 participates in regulation of Nox3, the role of the PX domain in Nox3 activity remains unknown In the process of cloning of human Noxo1, some spliced transcripts of the NOXO1...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
... consequence, native nAChRs with two different types of a/b interface can be expected to show agonist potencies that are different from those of the simple combinations of only one type of a and b subunits ... [38,80] This makes a total of six a-conotoxins, four muscle This 125I-labelled analogue of MII was used to visualize a active and two neuronally active forms, that have been population of nAChRs ... range of species but have no activity at neuronal subtypes The members of this subclass show remarkable selectivity for the distinct interfaces (a/c or a/d) within the muscle-type nAChR complex of...
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Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf
... traces, with the structure and PDB code shown below each panel (A) Overlap of isoform 337 with the structure of the longer isoform CfAFP-501 using the main chain of residues Thr23fiAsn90 in isoform ... of the structure can be attributed to the lack of a hydrophobic core typically found in globular proteins Instead, there is a rung of disulphides down the middle of the protein The addition of ... the top of the panel, while the C-termini are near the bottom (B) Overlap of individual coils of sbwAFP with LpxA and TmAFP with pelC Proteins are colored according to the label shown below the...
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