... patients treated with adalimumab by comparison withpatients treated with a placebo during the double-blind treatment period (0,88 for the adalimumab group versus 1,34 for the placebo group; p = 0,002) ... in patientswith ECF In general, patientswith inflammatory bowel disease represent a high-risk groupfor the formation of ECF, as a result of both the process of their disease and the need for ... remission in patientswith CD Infliximab has been shown to be effectivefor the treatment of FCD in adult patientswith peri-anal fistulas Infliximab has even been shown to sustain a response in patients...
... providing care forpatientswith severe personality disorder The present study is, as to the best of our knowledge, the first to examine Collaborative Care forpatientswith severe personalitydisorders ... indicative for positive or negative outcomes Informal carers Participants Patients This Collaborative Care Program is developed to improve the quality of care forpatientswith severe personalitydisorders ... substantial group of patientswith borderline or NOS personalitydisorders does, for different reasons, not participate in evidence based psychotherapeutic programs aimed at structural changes in personality...
... pulsed with autologous tumor cell lysates with or without intratumoral Gliadel wafer recently were closed for accrual At Duke University (NCT00890032), recurrent GBM patients are treated with autologous ... (NCT00293423) or newly diagnosed (NCT00905060) patientswith GBM Enrolled patients are being vaccinated with the heat shock protein peptide complex (HSPPC)-96 with or without concurrent TMZ therapy Heat ... involves patient treatment with CMVALT with or without CMV-DCs pulsed with pp65 mRNA Patients will also receive standard of care radiotherapy and TMZ Interestingly, patients whose tumor recurs...
... experience with ART forpatientswith TB in the DRC [1] Topics were introduced using PowerPoint® presentations, interactive question-and-answer sessions, group discussions and case studies, either with ... the burden of TB among people living with HIV/ AIDS are therefore urgently needed [3] HIV counseling and testing of patientswith TB and care for co-infected patients are key activities in the ... (page number not for citation purposes) Human Resources for Health 2009, 7:23 TB diagnosis, counseling strategies forpatients who refuse to accept their HIV status, management of patients who default...
... scale, each with a 6-point frequency response scale (Items to 6: = Never, = About time in 5, = About time in 3, = About time in 2, = About times in 3, = almost always) Item asks how many times in ... none, = time, = times, = times, = times, = or more times) There is also an independent eighth item which addresses overall quality of life – "If you were to spend the rest of your life with your ... interference with everyday activities item has a 5-point Likert-type response scale (0 = none of the time, = a little of the time, = some of the time, = most of the time, = all of the time) The...
... versions was developed for diabetes patients (n = 14) Five respectively four instruments referred to asthma and arthritis patients and three to patientswith COPD Aim of instrument For approximately ... varied across the different disease groups For example, self-efficacy scales for diabetes patients were most frequently correlated with physiological outcomes (for example HbA1c as a measure of ... in combination with input from experts (4 instruments [22,30,35,36]), followed by input from experts and patients without literature searches (for instruments [21,28,33]) Overall, for the development...
... Simulation of patientswith topographical disorientation A connected graph with 10 nodes and different weights for the links was constructed as shown in Figure We simulated patientswith five different ... in a uniform manner In the present case, however, we intend to route patients, each with unique characteristics The minimum distance route assuming uniformly processed packets is therefore not ... previously observed in patientswith acquired brain injury [9] Each patient was simulated 1000 times to account for route variations arising from random navigation when PC ≠ For the patient who...
... applicable in both patientswith hip or knee OA However, we have based our study only on patients undergoing total hip replacement, and therefore, further validation studies in patientswith different ... independent sample of patientswith hip OA and in different languages Besides, the original WOMAC has been used in patientswith hip or knee OA, consequently this 11items short form could probably ... goal is to involve as little effort as possible for both the patient and the physician Therefore, if using a shortened version the same information is collected but with little burden, the instrument...
... versions was developed for diabetes patients (n = 14) Five respectively four instruments referred to asthma and arthritis patients and three to patientswith COPD Aim of instrument For approximately ... varied across the different disease groups For example, self-efficacy scales for diabetes patients were most frequently correlated with physiological outcomes (for example HbA1c as a measure of ... in combination with input from experts (4 instruments [22,30,35,36]), followed by input from experts and patients without literature searches (for instruments [21,28,33]) Overall, for the development...
... function in AD patients receiving galantamine 24 mg/day for 12 months or placebo for months followed by galantamine 24 mg/day for months [51] Although patients who took galantamine 24 mg/day for 12 months ... measured with a questionnaire documenting time spent supervising and assisting with ADL, untreated patients required increased supervision by the caregiver and increased assistance with ADL over time, ... of 1,000 IU of vitamin E twice daily forpatientswith moderate AD Additional trials are needed to test the benefits of vitamin E in patientswith milder forms of AD Other alternative treatment...
... Figure 18 month follow before and after CRT intervention and at BMI of patients – up BMI of patients – before and after CRT intervention and at 18 month follow up Age of the patients and duration ... was forpatients An aspect of the intervention that seemed appealing forpatients was that the exercises and reflection on them involved thought processes and not thought content In the patients' ... intervention for AN patients This was done in a number of ways from adding new tasks to adjusting the delivery of the intervention For example, a monitoring form was used to report patient performance...
... survival rate forpatients without lymph node metastases (N-) and forpatientswith lymph node metastases (N+) The majority of patients (12/22) received SRS treatment as outpatients with curative ... All patients included in this study completed an informed consent form Patients were examined using PET-CT, MRI, and Ultrasound Prior to radiation therapy, biopsies were performed for all patients, ... Surviving patients † Additional non-recurrent patients treated, data presented for recurrent patients only unless otherwise noted ‡ Includes non-recurrent patients § Includes patientswith non-squamous...
... respectively (p = 0.035) Likewise, patientswith good performance status lived significantly longer The estimated 6-month OS was 66.9% and 37.5% forpatientswith a KPS of 90-100 and 70-80, respectively ... QoL were also compared for the time points before and months after the start of VMAT Fourteen (77.8%) patients completed questionnaires at both time points The reason for not completing the questionnaires ... both time points All other patientswith complete C30 and BN20 data did not reach this time point In these patients, no local or distant brain failure was observed One patient presented with...
... mortality of the patientswith stage II was 4.064 times higher than that of the patientswith stageI (p = 0.015) Systemic chemotherapy increased the risk of death of the patientswith early stage ... mortality of the patientswith chemotherapy was 3.659 times higher than that of the patients without chemotherapy (p = 0.042) In these 13 patients receiving chemotherapy, the number of cases with tumor ... 142.8~240.0 Gy) in 24 patientswith tumor size of 3~5 cm, 165.5 Gy (range, 142.8~212.2 Gy) in 10 patientswith tumor size of 5~7 cm and 144.0 Gy (range, 142.8~184.8 Gy) in patientswith tumor size...
... SLE With the exception of the live attenuated vaccines, other vaccinations should be kept up-to-date in patientswith SLE Caring forpatientswith SLE includes commonsense measures such as timely ... among patientswith SLE Guidelines are in place recommending the influenza vaccine and pneumococcus vaccine forpatientswith rheumatoid arthritis but similar guidelines have not been developed for ... likely to be prescribed to patientswith milder disease drugs as standard of care for all patientswith SLE without contraindications Competing interests The author declares that they have no...
... registration form will have baseline data on treatment issues This also will allow for within group analyses, giving information about the effectiveness of both implementation strategies separately Unfortunately, ... relatively small effect), with alpha = 0.05 and beta = 0.20, ICC = 0.05, a total of 51 practices with 10 patients each would be required, or 59 practices withpatientsTime frame Practice inclusion ... different forpatientswith systolic CHF compared to patientswith a preserved systolic heart function, so called diastolic CHF (See Table 1) Finally, new recommendations on the use of devices were formulated...
... recommend anticoagulation with warfarin forpatientswith a CHADS2 score of or higher, aspirin or warfarin forpatientswith a CHADS2 score of 1, and aspirin forpatientswith a CHADS2 score of ... generalised estimating equations (GEEs), with information sandwich (’robust) estimates of standard error to allow for within-cluster (within-general practice) correlation for dichotomous outcomes [40] An ... statistician with codes forgroup allocation to enable blinded analysis Ethical considerations For ethical reasons, GPs will receive summaries of data extracted from medical records for all their patients...
... future, at this time, we still recommend the combination of doxorubicin plus cyclophosphamide followed by paclitaxel forpatientswith TNBC, in the adjuvant setting Forpatientswith metastatic ... profiling study of 99 patientswith breast cancer, 41 of whom had triple negative disease They noticed that nine of the patientswith TNBC clustered together with the ER positive group When focusing ... also been coupled with other cytotoxic agents for neoadjuvant treatment; when used with epirubicin and 5-FU a pCR of 40% was achieved [60] In a similar study of 74 patients treated with cisplatin,...
... There are National Institute for Health and Clinical Effectiveness (NICE) guidelines defining standards of care, but studies of the quality of care forpatientswith diabetes suggest less than ... Data held within practice computers on the performance of clinical behaviours and measures of physiology These data will be collected in two ways First, for all registered patientswith diabetes ... delivery forpatientswith diabetes will be examined: glycaemic control, BP control, foot examination, weight management, patient education, and self monitoring Anonymous clinical records of patients...
... of managing patientswith chronic disease is high, and is predicted to rise to 80% of US health care dollars by 2020 [1], identification of effective ways to improve care of patientswith chronic ... diabetic patients Confirmation of these findings forpatientswith other chronic diseases is necessary In addition, while we were able to address the potential bias inherent in studies with unit ... strategy for organizational interventions to improve outcomes of patientswith Type II diabetes Medline search strategy to identify studies of organizational interventions to improve outcomes for patients...