... essential for the binding of CP12. The presence of this region at the interface of GAPDH andCP12 could also explain the kinetic changes o bserved for the binding ofthe substrate when the wild-type ... all mutantGAPDHs indicate no changes ofthe global structure of the mutants.To test wh ether the interactions of these mutants with the other partners o f the GAPDH–CP12–PRK complex wereimpaired, ... Comparison of the kinetics of these mutants with those ofthe wild-typerecombinant GAPDH shows that the beh aviour of R197Amutant is not affected b y the m utation, suggesting that the active...
... will determine whether they can convince the UK consumer that the product is the right one. The most challenging aim ofthe thesis is to assess the UK consumer awareness of Slovenia as a ... drunk in the UK comes from the off-trade, in terms of price, only 60% ofthe total expenditure on wine is in the off-trade. This reflects the difference in average price per bottle between the on-trade, ... building. Certain theorists have defined the various stages in the strategic marketing planning process. The majority of them focus on the importance of one crucial stage: the environmental...
... composed of subunits that have the same structure as the original monomer, with the exception ofthe ‘hinge loop’ that connects the tail with the rest ofthe structure (often referred to as the ‘body’). ... Glu103 residues of one subunit andArg104 residues ofthe other [8]. In this dimer, the rel-ative positions ofthe two subunits would prepare the molecule for the swapping ofthe N-terminal domainwhile, ... from the rest of the protein during thermal denaturation would alsorequire a substantial unfolding ofthe whole proteinand thus dissociation ofthe N-terminal domain from the rest ofthe protein...
... Obviously, the formation process and mechanism of TiO2 nanotube is different from that of carbon nanotubes. Study on its formation process will helpful to understand the mechanism of formation of ... in the stage of alkali treatment of polycry- stalline TiO2, and not in the stage ofthe acid treatment following the alkali treatment. This conclusion differs from Kusuga7. 100 mL of 9 ... nanotubes in the solution. In this paper, using transmission electron microscope (TEM), the formation process of TiO2 nanotubes in the concentrated NaOH solution was investigated. The results...
... to the family Bathydraconidae. A compar-ative analysis ofthe sequences of these AFHbs reveals the occurrence of substitutions in important regions of the protein, e.g. the heme pocket and the ... evolves towards the formation of the hemichrome state (24–30 h). The overall oxidation process of HbTbCO at pH 6.0 is faster than at pH 7.6.However, the relative intensity ofthe bands in the visibleregion ... 2004 The variations detected at the level ofthe tertiarystructure propagate to the quaternary structure through the a1b2interface. The displacements of helix F and FGcorner ofthe b subunit,...
... described in the Materials and methods. Completion ofthe hydrolysis wasconfirmed by the disappearance ofthe (Met1)-ONC(M23L) signal in the MALDI-TOF mass spectra 1 h after the addition of AAP. The ... calculating the slope of the curves of Pyr-ONC (M23L) vs. time. From the rates of cyclizationshowninTable1,itcanbeinferredthattheformation ofthe N-terminal pyroglutamyl is not dependenton pH in the ... hydrogen bonded to the e-amino group ofthe Lys9 side-chain, which simultaneouslyinteracts with the main phosphate ofthe substrate [32]. The closer positioning ofthe N-terminus to the mainprotein...
... authenticmember ofthe Family I soluble PPases. We also provideinformation concerning the kinetics and properties of the enzyme. More strikingly, we show a novel role ofthe PPaseenzyme in the ... ecdysis of an old cuticle and deposition ofthe components of a newcuticle that are synthesized in the hypodermis and aresecreted across the hypodermal membrane into the spacebetween it and the ... The theoretical curve drawn is forthebesttvaluesofKmẳ 0.117 0.006 mM,andVmaxẳ849.005 14.635 lmolặmin)1ặmg protein)1. The inset in (A) repre-sents the linear transformation of the...
... model ofthe role of point of view in problem solving. SUMMARY We have reported here a three pronged approach to the study of problem solving action and report: I) the collected of data ... 2) development of a process model of these behaviors, and 3) use of coding techniques to extract traces of "critical phenomena" from the transcripts for evaluating the model. So far, ... of problem solving phenomena: the changes in the problem solver's organization ofthe problem ("point of view"), and systematic multl-utterance structures used to express the...
... find how state ofthe art sensor technology supports the brewing process. Rising accuracy ofprocess sensory, along with high repeatability enables the user to run a process in the most efficient ... harvest-to-harvest. The brewer needs to react on these changes to prepare a stable quality of beer, and even more, it must taste the same all year, each and every year, to fulfill the expectation ofthe ... across the lautertun bed is commonly using pressure transmitters with metal membranes. Due to the abrasive nature ofthe mash and cleaning procedure the membranes are often damaged. The PMC71...
... Bryggerhøjskole The Scandinavian School of BrewingStabilisationDefinition of Stabilisation The expression stabilisation is used specifically about the procedure by which the brilliance ofthe finished ... Bryggerhøjskole The Scandinavian School of Brewing The brewing process The Scandinavian School of BrewingAxel G. KristiansenAxel G. Kristiansen Den Skandinaviske Bryggerhøjskole The Scandinavian School of ... Bryggerhøjskole The Scandinavian School of BrewingTaste TestingThorough routine production control and frequentlaboratory tests during and after the brewing process ensure that the quality ofthe beer...
... introduced the projects involved, and the structure ofthe German-Engllsh transfer mechanism, offering specific examples ofthe transfer process for some ofthe features present in the IS analysis. ... complex requirements on both the linguistic theories involved and on the theories of translation. Perhaps the most refreshing aspect ofthe endeavour has been the new perspective which one ... have made crucial use ofthe upper model in constructing our combination ofthe two compo- nents. In effect, the upper model can often mediate between the results ofthe MT analysis, expressed...
... METHODLOGY 3.1. Aims ofthe project One of questions that the author wondered from the beginning of this thesis is whether any connections between the managerial decision making process and cost ... increase the number ofthe ending inventories as well as the profit ofthe organizations as mentioned above. This not only can be considered as a strategy ofthe new comers to attract the investments ... Sometimes, the ending inventories of these companies can be more than 50% ofthe total number of products that they produce each month. This is because the percentage of depreciation in value of raincoats...
... necessary to the company. Since the roles of cost accounting are more and more important to the company, and their impacts take an essential role in choosing decision of manager, the viewpoint of this ... methods of Vietnam companies, the research evaluates the usage of cost accounting of managers in decision-making process. There are many ways to carry out a research; however this thesis only ... implementation ofthe policy ofthe country annexed the pharmaceutical companies ofthe city, districts with pharmaceutical companies – Ha Tinh Pharmaceutical Materials. All medicine counters in the...
... account ofthe varieties of institutional form and the nature of the policy area, but the unique features ofthe American system com-pound the problem and beg the question ofthe significance ofthe ... logics (whether of law, eco-nomics, or yet others) as tools that structure the process. Beyond these themes and the theory-building that other data in thisbook suggests, changes in the regulatory ... conceive of the American way of regulation as a permanent “other” that stands only asafoilfortherestoftheworld.Asoneobserverframedthecontempo-rary concern for regulation as a mode of governance,...
... management the manifestation of the capacity of adaptation to the environment changes and in the same time of market prevision, so that to benefit ofthe advantages of forecast and adaptation to the ... sold: the product; - the sales place: the ambience created by the interior organization of the shop; - the manner of selling: sales methods. In a synthetic manner, the cardinal points of merchandising ... upon the consumers. 3. Unit of measurement (kilogram, liter, piece, etc); 4. Necessity. It refers to the decision of buying both ofthe consumer and ofthe seller. The buying decision of the...