... These workers inthe other disciplines will be informed about the project and receive relevant information in line withthe multidisciplinary guideline All materials are offered paper based in ... Guidelines forthe diagnosis and treatment ofacute and chronic heartfailure 2008: the Task Force forthe Diagnosis and Treatment ofAcute and Chronic HeartFailure 2008 ofthe European Society of ... developed inthe Netherlands with a literature study in 2002, expert input, and tested in various projects inthe Netherlands [20] Our main factors for ordering the barriers are related to the innovation,...
... differences in cost per QALY with increasing age and disease severity Our finding is in parallel withthe study by Hamel and colleagues inpatientswith pneumonia and ARDS [14] However, in their study the ... therefore, used number of individual TISS points for each patient during their ICU stay and the exact number of ward days for cost calculation The average cost for one TISS-point (48€ per TISS point) ... factors 48 hours before ARF were recorded inthe clinical report form The clinical report form data were combined with an internetbased interface to the quality consortium database Page of Qol Group,...
... also noted inpatientswith ARF There was a higher incidence ofacute gastrointestinal tract (GIT) bleeding inpatientswith ARF Such bleeding was in turn associated with greatly increased mortality ... also studied the effects of theophylline in RCN A total of 39 patients undergoing radiocontrast study were recruited Forty-five minutes before the administration of radiocontrast, thepatients were ... fenoldopam, theophylline) and endothelins Acute inflammatory infiltrate of tubulo-interstitium Acute tubular necrosis (ATN) 35 1 Pathophysiology ofAcute Renal Failure (ARF) Besides recognising the pathophysiological...
... improved the prognosis ofpatientswith AMI, the inhospital mortality rate of AMI patientswith cardiogenic shock remains as high as 55% [8] The main cause for early mortality (within 48 h of onset of ... appraisal of randomized clinical trials of IABP therapy in AMI patients Thorough critical appraisal involves determining the validity ofthe study design, understanding the results and deciding whether ... hemodynamic instability necessitating the use of an IABP, cardiogenic shock, bleeding diathesis prohibiting the use of aspirin or heparin, precatheterization administration of thrombolytic therapy,...
... duration of weaning and the total duration of MV The 21 patientsinthe ET group were demographically similar to the 53 patientsinthe ST group, except forthe greater number ofpatientswith TBI in ... to perform a tracheostomy at a point that has been defined by other investigators as 'early' Nonetheless, the findings of our study provide the basis for re-examining whether the timing of tracheostomy ... patientswithacute respiratory failure Physician belief inthe utility of tracheostomy, patient selection and the lack of blinding may introduce bias, leading to difficulties in comparing patients...
... standards Because ofthe nature ofpatients' injuries, subjects in this clinical study were incapable of granting informed consent Investigators therefore obtained informed consent from the subject's ... assessing neuroprotective properties of progesterone inthepatientswithacute severe brain trauma The effects of progesterone on neurological outcome ofthe TBI patients remain unclear The purpose ... (Tianjing Jinyao Pharmaceutical Co Ltd, Tianjing, China) or matching placebo within hours ofthe documented time of injury Qualifying patients were randomly assigned in a 1:1 manner to receive the...
... Guidelines forthe diagnosis and treatment ofacute and chronic heartfailure 2008: the Task Force forthe Diagnosis and Treatment ofAcute and Chronic HeartFailure 2008 ofthe European Society of ... Tavazzi L, Maggioni AP: Roleof betablockers inpatients admitted for worsening heartfailurein a real world setting: data from the Italian Survey on AcuteHeartFailure Eur J Heart Fail 2009, 11:77-84 ... known to temper the sympathetic nervous system, including the reduction ofheart rate Therefore, negative systemic effects inthe disease progression of cardiovascular disease including CAD, CHF...
... for infection” [16] Such patients were included inthe original study if blood cultures were drawn from them upon admission by order ofthe attending physician Almost 45% ofthepatientsinthe ... participated inthe design ofthe study, the process of data analysis and interpretation, and helped in preparing the manuscript for publication Competing interests The authors declare that they have ... patientswith sepsis admitted to general internal medicine departments, for all ofthe examined time points The scoring systems evaluated inthe present study are simple and based on available clinical...
... deposits in other locations Facial wasting, especially ofthe cheeks Loss of subcutaneous fat in all parts ofthe body, most visibly inthe limbs Wasting ofthe buttocks Prominent leg veins Others ... to light by the “3 by 5” initiative with vigorous efforts; finally, to gather, analyze, interpret and disseminate strategic information about the scaling-up of HIV/AIDS programmes inthe health ... location of facial fat inpatientswith lipoatrophy using the volumetric MRI scanning and to compare the pattern of soft tissue depletion with that seen inpatients without lipoatrophy To quantify the...
... competes with membrane-bound Fas for ligand binding, therefore reducing apoptotic signaling Procedures All treatments including milrinone dosing was at the discretion ofthepatient's attending physician, ... failure, and the effect milrinone in ischemic subset ofpatients deserves further investigation Conclusion Initiation of milrinone therapy inpatientswith severe heartfailure and reduced cardiac ... Mabuchi N, Sawaki M, Kinoshita M: Interleukin-6 spillover inthe peripheral circulation increases withthe severity ofheart failure, and the high plasma level of interleukin-6 is an important...
... pathogenesis ofheart failure, inthe identification of subjects at risk ofheart failure, risk stratification, therapeutic agents response monitoring [17] The aim of this study was to investigate the inflammatory ... described here forthe first time, was the increase of IL-9, and decrease of IL-5, IL-7 and IFN-g plasma levels inpatientswith chronic heartfailure Using the bioinformatic analysis from the http://www ... stable heartfailurefor six consecutive months were enrolled at the Cardiology Unit ofthe Catholic University of Sacred Heartof Rome out of 210 patients admitted to the unit during the same...
... pathogenesis ofheart failure, inthe identification of subjects at risk ofheart failure, risk stratification, therapeutic agents response monitoring [17] The aim of this study was to investigate the inflammatory ... described here forthe first time, was the increase of IL-9, and decrease of IL-5, IL-7 and IFN-g plasma levels inpatientswith chronic heartfailure Using the bioinformatic analysis from the http://www ... stable heartfailurefor six consecutive months were enrolled at the Cardiology Unit ofthe Catholic University of Sacred Heartof Rome out of 210 patients admitted to the unit during the same...
... obtained in 142 ofthe 184 patients who discontinued infliximab therapy Fifty percent ofpatients were switched to another biological therapy (Table 2) Evolution ofthe DAS28 score over time Patients ... onward All patients gave written informed consent Variables evaluated inthe prediction of infliximab continuation To predict long-term continuation of infliximab therapy early inthe treatment ... week 22 These findings indicate that the likelihood of withdrawing from therapy increases by 70% to 90% when the DAS score increases by one unit To translate this hazard ratio in terms of sensitivity...
... highlights the need for extreme vigilance and a high index of suspicion for AFE by the attending physician in a case of any postpartum individual with respiratory failure, especially inthe presence of ... conceived ofthe idea forthe publication, performed the literature search and was the principal writer ofthe manuscript, CD helped to draft the manuscript and assisted withthe collection of biomedical ... Written informed consent was obtained from the patient for publication of this case report and any accompanying images A copy ofthe written consent is available for review by the Editor -in- Chief of...
... 100]) at the time of initiation of continuous RRT (CRRT) to be associated with lower survival, independent of severity of illness This finding was further confirmed in two additional investigations ... forthe Kidney (BEST Kidney) Investigators: Timing of renal replacement therapy and clinical outcomes in critically ill patientswith severe acute kidney injury J Crit Care 2008 [Epub ahead of ... Changes inthe incidence and outcome for early acute kidney injury in a cohort of Australian intensive care units Crit Care 2007, 11:R68 Hoste EA, Schurgers M: Epidemiology ofacute kidney injury:...
... parameters forthe calculation were not collected as part of routine practice This is consistent withthe findings ofthe VA/ NIH group in their pre-trial survey that assessment ofthe delivered dose of ... Group for Treatment of ARF inthe ICU A randomized clinical trial of continuous versus intermittent dialysis foracute renal failure Kidney Int 2001, 60:1154-1163 Page 13 of 14 (page number not for ... to be surgical patientsThe mean serum creatinine at RRT initiation was 265 μmol/L Nearly 60% of all patients were in RIFLE class Failure at RRT initiation A small minority ofpatients did not...
... hemodynamics in ALI/ARDS patientswith normal IAP or IAH However, PEEP significantly increased EVLWI inpatientswith normal IAP but not inpatientswith IAH IAH, within the limits of IAP measured inthe ... 2008, 20 patients meeting AECC criteria for ALI or ARDS with and without IAH were included inthe study As the inclusion rate during the study period was similar we evaluated 10 patientsin each ... exchange in ALI/ARDS patientswith increased IAP compared withpatientswith normal IAP [7] More recently, in a study including mainly extrapulmonary ALI/ARDS patients, a strategy titrating PEEP...
... during the clinical course inpatientswith established AKI Therefore, we aimed to investigate the outcome-specific value of NGAL, measured at initiation of RRT in critically patientswith severe ... prior to initiation ofthe first RRT Enrollment was performed in a randomized consecutive fashion after obtaining written informed consent from thepatients or their legal representatives If the patient ... according to the International Sepsis Definitions [25] Patient groups were comparable with respect to baseline demographics, LOS inthe ICU before start of RRT, indications for RRT, and the proportion...
... early initiation may expose other patients unnecessarily to the risks of RRT [5] The AKI Network reviewing the evidence in this field, stated that the indications for RRT must be viewed within the ... severity inthe RRT group • Within the group of RRT patients, this study confirmed that mortality was equal inpatients treated with intermittent or continuous RRT • An individualized approach, integrating ... designs There is still insufficient data to determine absolute indications and optimal timing for initiation of RRT inpatientswith AKI In some patients, early start of renal support may improve...
... Importantly, the incidence is increasing [48] These critically ill patients have a risk of death approaching 60% [2,7] The decision to initiate RRT is a modifiable intervention for these patients; ... remaining studies [21,34-37,40,42] (Table 3) Six studies defined timing of initiation of RRT based on cut-offs in serum urea [15,21,34,35,37,42], two studies based on cut-offs in serum creatinine ... identifying the “optimal timing of initiation of RRT” in AKI have been given the highest priority for investigation by theAcute Kidney Injury Network (AKIN) [24,25] Accordingly, we conducted a systematic...