... The normalised V d l G reference signals d3.i 1v d is ON and s, is OFF S, is OFF and S, is ON s 3is OFF and s, Ifthe reference signal vil, ( vLl , vikl ) for the rectifying operation and the reference ... on and off in the following manner to generate the PWh4 waveforms of the rectifier AC-side phase , voltages vjl, vi,, and vi, , d3vl: I v d and s, s, is ON when is ON and S, is OFF when is OFF ... which isthe sum of currents i, and i in Fig.3(a) , The current is, has a distorted waveform caused by the current i,, Next, the operation of the system when the PWM rectifier compensates the...
... on They may believe that if there is a better way, they should have seen it themselves years ago and if they didn't they must be an idiot Since they didn't see it and they can't be an idiot, there ... k ' strategy They can get into a real argument What they are competing about is basically who is going to change, whose opinion is wrong, and similar issues This then, in a sense, is a second ... it is suggested that the computer is a medium for humans to communicate with each other VIA Viewed in this way, possibilities exist for the computer to become an acti~ and aelecti~ rather than...
... this shows the chasm between statisticians and dynamicists and the importance of having the correct model through which the data analysis is pursued FEBS Journal 275 (2008) 2372–2384 ª 2008 The ... the Newman et al study [7] and found that 155 of these made the discrimination categories and were further analyzed by these authors The variance in this group was much greater than that in the ... measure of the information content of the system as expressed in the vectors and it is clear that in all three experiments the system is globally oscillatory The disadvantage of SVD analysis is the...
... participants Therefore the total potential liquidity in the system isthe sum of the T2NDCs In practice this is not quite true since the Bank of Canada is also a participant in the LVTS and acts ... This data set consists of 272 days in which the LVTS was running The participants in the sample consist of members of the LVTS and the Bank of Canada For the purposes of this study we exclude the ... cash distribution and the stationary distribution) The second block is a random walk Metropolis-Hastings step to draw a realization 12 The precision is just the inverse of the variance 11 of the...
... anti-human Golgin 97 (A) serum, mouse anti-human LAMP2 serum (D), mouse anti-human CD63 serum (G), mouse anti-human MPR serum (J) or mouse anti-human EEA1 serum (M) Primary antibodies were visualized ... by the anti-HA serum (Fig 4B, lanes and 5) As these proteins are also recognized by the anti-FLAG serum, they must possess both residues 38 and 381 and therefore be close to full-length RNF13 The ... TM sequence Consistent with this, our analysis of cellular membranes washed with high-salt solution establishes that RNF13 is indeed an integral membrane protein This is consistent with data...
... into theactive site of the PAL model gave further insight into the role of the amino-acid residues in catalysis (Fig 6A) These ligand-binding models confirmed the hypothesis concerning the p-stacking ... s)1 The mutant S203A is therefore 435 times less active than the wild-type enzyme This isan 10 times higher activity that was previously reported for this active site mutant [52] The counterpart ... less active than the wild-type enzyme and is therefore the least active PAL mutant examined so far Y110 probably plays a very important role that can be explained by enzyme modelling Homology modelling...
... This characteristic, first described for the polypeptide chains of bullfrog ferritin [9], is common to fish ferritins on the basis of the available sequences A further distinctive property of the ... by a significant decrease in ellipticity relative to pH 3.0, a blue shift of the zero intercept, and a change in the ratio between the 208 and the 222 nm bands (Fig 4A) In particular, the molar ... irreversible, and the spectra measured at the end of the cooling phase were different from those of the native apoprotein The midpoints of the transitions at pH 7.0 and pH 4.0 correspond to 82 and 74...
... segment is present in the shewasin A amino acid sequence The Asp of theactive site motif from the N-terminal domain (marked with an asterisk) was mutated to an Ala to generate theactive site mutant ... kDa), and aprotinin (6.5 kDa) (Paris, France) The last of these peptides was found to be cleaved readily, and the rate of hydrolysis was monitored at an excitation wavelength of 328 nm and an emission ... of these putative catalytic Asp residues provides further strong evidence that this enzyme isanactive pepsin-like AP To the best of our knowledge, this isthe first documentation of such an...
... was the first clergyman that had ever been a member of it It consisted of artists and other gentlemen, [86] an equal number of each Cole and Durand and Ingham and Inman and Chapman and Bryant and ... for historical Christianity The revelation in our nature, then, and the revelation in the Scriptures; the proper place of each in any just system of thought and theology; what importance is to ... be an improvement upon all existing ones, Roman Catholic, Church of England, or any other If in the highest ranges of human attainment there is to be an advancement of age beyond age, surely there...
... together, these data establish LIN54 as an essential member of the LINC ⁄ DREAM complex delayed entry into mitosis [9] To address whether this isan isolated function of LIN9 or whether it is ... [12,13] Another conserved core subunit of LINC is LIN54 LIN54 homologs are present in many species, including plants (Arabidopsis thaliana), invertebrates (C elegans and Drosophila melanogaster) and ... progression and mitotic entry is not an isolated function of LIN9 and B-MYB, but that it is mediated by the LINC complex Our study demonstrates that LIN54 isan integral and essential subunit of this...
... folds into the secondary structure of the native toxin On the other hand, the spectra of the T2 and T2¢ fragments exhibit more disordered structures than that of D4 These data imply that their extra ... that of the D4 fragment (Fig 3, lane 4) The resultant proteolytic fragments were recovered from the gel (lanes and 8) and their N-terminal sequences were analyzed by a protein sequencer The N-terminal ... supported by grants from the Japan Science and Technology Corporation, the Japan Science Society (to Y.S.) and from a Grant-in-Aid for Scientific Research from the Japan Society for the Promotion...
... invariant under a translation in the range of u and f Furthermore, the construction of f from u is also invariant under a translation in the range of u and f By this we mean that if u is replaced ... the hypotheses For example, in Theorem 1.0.1 we mean that ε and the constants associated with the (1, q)-Poincar´ inequality depend only on the constant p, the doubling e constant of μ, and the ... [43] The novelty here is not the extension, but rather that there is a Lipschitz extension that satisfies (10) Observe that because M # is uncentered, we have U8k is open We can then apply a standard...
... toxophallin (Edman degradation analysis; Fig 2) (B) Partial nucleotide sequence and deduced amino acid sequence of the toxophallin The amino acid translation is under the second nucleotide of the corresponding ... action in the organism In conclusion, in the present study, a novel cytotoxic protein was isolated from the death cap and characterized The physico-chemical, chemical and biological characteristics ... were in the range 14.4–94 kDa In-gel digestion, MS analysis and Edman sequencing Purified toxopallin sample was subjected to SDS-PAGE, and protein bands were visualized by Coomassie Brilliant Blue...
... Completion of the parasitic life-cycle requires rapid changes in its environment such as the stimulation and inhibition of cell division An important issue facing global health isthe need for ... western blot analysis of the eluate and flow-through fractions after the different steps of size-exclusion chromatography with anti-(eIF-5A) and anti-DHS Ig (Fig 5, eIF-5A, lane B) Anti-(eIF-5A) ... cases with a concomitant isomerization [3]; the binding can be followed chromatographically using a His6-tagged apoprotein and the resulting increase in absorption and band-shift can be followed spectroscopically...
... residue and the PGIS N-terminus had no significant effect on the subcellular localization of COX-1–10aa–PGIS in the cells The idea that the PGIS domain is located on the cytoplasmic side of the ER and ... these target tissues On the other hand, there isthe COX-1 enzyme, which is well known to have a similar function (coupling to PGIS to synthesize PGI2 in vitro and in vivo) to that of COX-2 The ... addition, we thank R Kulmacz and Lee-Ho Wang for providing the original wild-type cDNAs of human COX-1 and PGIS, respectively We also thank Anita Mohite for her assistance with the anti platelet...
... extract and 20 lgÆmL)1 gentamicin (Centafarm Services, EttenLeur, the Netherlands) The human small cell lung cancer (GLC4) cell line and GLC4 cell line transfected the human multidrug resistance ... NIM811 and PSC833 induce an increase in cytosolic [Ca2+] and production of ROS The discrepancy in the effects of PSC833 between GLC4 cells and isolated mitochondria versus the consistency in the ... effects on MPTP The CsA analog SDZ-PSC833 (PSC833) may serve as a useful control substance in this context, because it isan inhibitor of P-glycoprotein rather than MPTP, and is devoid of calcineurin-inhibiting...
... This page intentionally left blank A Tear Isan Intellectual Thing For a tear isan intellectual thing, And a sigh isthe sword of an angel king, And the bitter groan of the martyr's woe Isan ... from a complex and conflicting history The antithetical meaning of primal expressions may be as basic and inevitable as the antithetical meaning of primal words Antithetical meaning is in fact open ... feeling and conscience would be selfish and base, even though they should be persuaded that the fool, the dunce, or the rascal is better satisfied with his lot than they are with theirs They would...
... interests The authors declare that they have no competing interests Authors' contributions BN carried out the immunohistochemical analysis, performed the statistical analysis, and drafted the manuscript ... performed the statistical analysis and drafted the manuscript KJ participated in the conception and design of the study, performed the histopathological re- Nodin et al Journal of Ovarian Research ... manuscript NZ and EN carried out the immunohistochemical analysis and drafted the manuscript JB collected the clinical data JM participated in collection of clinical data and drafted the manuscript...