the growth of genbank and the protein data bank has been astronomical
Tài liệu The Protein Data Bank: a historical perspective ppt
... 2004) The accessibility of the data and the growing importance of understanding the data has meant that the PDB’s user community has grown from the community of crystallographers that banded together ... uniformity, the wwPDB has reviewed and documented all data processing practices among the member sites The wwPDB has also taken on the task of reviewing all the files in the archive and has very ... tools around the world, uses the same principles and algorithms All Figure Growth of the number of cryoEM structures in the PDB and the number of related maps in the Electron Microscopy Database...
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THE PROTEIN DATA BANK pptx
... the structures in the PDB bound to a particular ligand or ligand type In addition to the efforts of the PDB to remediate the older entries, the EBI has also corrected many of the records in the ... preservation of software, derived data, ancillary data and all other computerized and printed information; automatic archiving of all depositions and the PDB production resource; and maintenance of the ... capabilities of the PDB Figure The various query options that are available for the PDB • The final curated data files (in PDB and mmCIF formats) and data dictionaries are the archival data and are...
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Báo cáo hóa học: " Low Temperature Growth of In2O3 and InN Nanocrystals on Si(111) via Chemical Vapour Deposition Based on the Sublimation of NH4Cl in In" pdf
... decomposition of NH4Cl enhances the porosity of the Al melt thereby promoting the transfer of Al into the gas stream On the other hand, the reaction of NH4Cl and Al leads to the formation of AlCl3 ... uniform and the density of the dendrites was dependent on the amount of In and the distance of the silicon from the In The In2O3 NCs grown at TG = 1000 °C on silicon exhibited clear peaks in the ... flow of N2:NH3 it leads to the formation of AlN around the source of Al which in turn inhibits the transfer of Al into the gas stream and consequently the growth of AlN At high temperatures the...
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báo cáo khoa học: " All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein" pdf
... down-regulation of survivin and up-regulation of Bax proteins ATRA suppressed the phosphorylation of KIT protein KIT protein is one of the most important molecules in the pathogenesis of GISTs Despite ... cell growth curve which represents the effect of different concentrations of ATRA Results were calculated as the percentage of the control values Panel B shows the effect of ATRA on adherence of ... completely the migration of these cells (data not shown) All together, the data suggested that ATRA may be useful to prevent the invasion or metastasis of GIST cells Cytotoxic effect of combination...
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Báo cáo sinh học: "Analysis of the real EADGENE data set: Comparison of methods and guidelines for data normalisation and selection of differentially expressed genes (Open Access publication)" potx
... estimate of the background intensity, and therefore no further background correction was possible on these data Detection of differentially expressed genes 637 2.2 Normalisation of the data 2.2.1 Data ... give the possibility to study the changes of expression of thousands of genes simultaneously depending on the pathogen A large variety of methods for normalising and analysing microarray data has, ... array BTK2-74 was different from the other slides given the mean, minimum and maximum, and should be deleted from the analysis M-A plots of the raw data were atypical and showed a clear ‘fishtail’...
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INVESTIGATION OF THE FUNCTIONS OF p23 AND COAT PROTEIN OF HIBISCUS CHLOROTIC RINGSPOT VIRU
... centrifugation, the mixture was separated into a lower red, phenolchloroform phase, an interphase, and a colorless upper aqueous phase RNA was remained exclusively in the aqueous phase The volume of the ... potential The construction of a molecular model that confines physical interactions established between the components of the host cell and virus is the foundation of the emerging discipline of systems ... and Padmanabhan, 2007; Dodds and Rathjen, 2010; Elena et al., 2011) Furthermore, the own proteins and small RNAs of a virus interact and compete in replication cycle (Guo et al., 2001), and these...
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Controlled facet growth of gan and the overgrowth with zno
... smoothness of the growth front (a) Nucleation of GaN islands inside the stripe pattern aligned along the [112 0] direction The merging of these islands resulting in the ¯ formation of a slow growth ... photograph shows the Singletron accelerator in the background and the foreground is the 10° beam line, the 30° beam line and the 45º beam line 29 Fig 2.5 The diagram of the setup structures of the RBS ... dependence of the diffusivity of most gas species In this region, the growth rate of GaN, for example, is faster than the transport of the reactants through the boundary layer and the 24 Chapter growth...
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Tài liệu Protein Data Bank Contents Guide: Atomic Coordinate Entry Format Description Version 3.20 Document Published by the wwPDB ppt
... ID ID code code code code code code code code code code code code code code of of of of of of of of of of of of of of related related related related related related related related related related ... and precede series information The name and number of the report is given in parentheses, and the name is preceded by "REPORT:" and a space * Reconstruction of publication name: The name of the ... cataloging of the Library of Congress, the National Library of Medicine, and the British Library, in that order If a book is part of a monographic series: the full name of the book (according to the...
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Published quarterly by the Research Collaboratory for Structural Bioinformatics Protein Data Bank ppt
... we find that their fascination with the beauty of the images and animations interferes with higher level thinking about the structures themselves One of the goals of establishing the rubric is ... Academy Princeton The Lawrenceville School Cherry Hill East and their prebuild model of hemagglutinin A rubric was used to award points for the accuracy of the model and for the addition of materials ... 2 RCSB Protein Data Bank Newsletter Data Deposition and Processing Data Query, Reporting, and Access Deposition Statistics Improved Ligand Searching In the first quarter of 2010, 2065...
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rapid anodic growth of tio2 and wo3 nanotubes in fluoride free electrolytes
... minutes Changes in the conditions not affect the geometry of the individual tubes – rather they affect nucleation density and growth rate The final surface coverage and amount of tubular bundles ... ratio of Ti to O is : (matching TiO2) and the Cl content in all samples is lower than 3% (from the traces of the electrolyte remaining in the tubes) The small Al peak stems from the screw of the ... required, but also the optimized concentration of the ions in the solutions as well In order to gain more insight in these structures, we investigated them further by TEM and analyzed the composition...
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On interaction motif inference from biomolecular interactions riding the growth of the high throughput sequential and structural data
... biomolecules into and out of the cell, and, regulate the production of themselves or other proteins In order to accomplish these functions, proteins often works together with another protein or RNA ... attached These figures are taken from the Wikimedia Commons of databases list protein domains which are derived from the increasingly larger protein structural data in the Protein Data Bank Examples of ... cell involve one or more protein( s) while some other involve both the protein and RNA These proteins and RNA interact with each other and form functional complexes They either stay complexed to...
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Changes of temperature data for energy studies over time and their impact on energy consumption and CO2 emissions. The case of Athens and Thessaloniki – Greece
... meteorological stations of the National Observatory of Athens (NOA) [8] and of the Aristotle University of Thessaloniki (AUTh) [9] The results for the two decades are compared and the existing differences ... trend in the eastern and south-eastern parts of the Mediterranean, indicating a less frequent expansion of the low pressure over the area and therefore a weakening of the Etesian winds and a subsequent ... values of HDD were reduced in the second decade, while the monthly and yearly values of CDD were increased The reduction in the yearly values of HDD was in the range of 9.5 to 22% in Athens, and...
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Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf
... a candidate target of miR-23a miR-23a expression level 20 growth activities at the same time points (Fig 2A) To detect the effect of miR-23a on the long-term and independent growth activity of ... and colony formation assays confirmed the active role of miR-23a in the growth promotion of malignant cells The fundamental function of miRNAs is to regulate their targets by direct cleavage of ... on the expression of IL6R by RT-PCR and western blot, and found an inverse correlation between miR-23a and IL6R expression at both the mRNA and protein levels To confirm the direct regulation of...
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Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc
... Although the occurrence of family 33 CBPs has been known for some time [23], the present results provide only the third demonstration of the accessory function of these proteins The effect of LlCBP33A ... cloning of the chitinase and CBP, as the N-terminus of the latter protein should be free of non-native amino acids after removal of the afnity tag (because amino acid one of the mature protein ... containing 100 lm of (GlcNAc)14 was analysed at the start, in the middle and at the end of each series of samples The resulting average values of the standards (displaying standard deviations of < 5%)...
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Tài liệu Báo cáo khoa học: The effect of small molecules in modulating the chaperone activity of aB-crystallin against ordered and disordered protein aggregation pdf
... aB-crystallin (i.e the effect of the additive on the aggregation of the target protein is independent and different from that of the chaperone) The standard errors associated with this theoretical percentage ... decrease in the amount of precipitation in the presence of high concentrations of Arg-HCl in the absence of the chaperone precluded analysis of the effect of this concentration on the protective ... analysis of the effect of these concentrations on the chaperone activity of aB-crystallin (Fig 4B,C) None of the compounds had an effect on the morphol- A C 940 B ogy of the amyloid fibrils formed (data...
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Tài liệu Báo cáo khoa học: Effect of ionic strength and oxidation on the P-loop conformation of the protein tyrosine phosphatase-like phytase, PhyAsr docx
... Protein Data Bank: 3D1O), 400 mm (PhyAsrI400; Protein Data Bank: 3D1Q), and 500 mm (PhyAsrI500; Protein Data Bank: 3D1H), and with the catalytic cysteine (Cys252) oxidized (PhyAsrox; Protein Data Bank: ... Bank: 1U24) and with Cys252 fully oxidized (gray) (Protein Data Bank: 2PT0) with 100 lm H2O2 for 45 and solved the structure of the oxidized protein (PhyAsrox; Protein Data Bank: 2PT0) The P-loop ... ionic strengths of: (A) 200 mm (Protein Data Bank: 2PSZ); (B) 300 mm (Protein Data Bank: 3D1O); (C) 400 mm (Protein Data Bank: 3D1Q); and (D) 500 mm (Protein Data Bank: 3D1H) Fig S2 Sigma-weighted...
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Tài liệu Multiple Vulnerabilities qualitave data for the stydy of orpharns and vulnerable children in South Africa ppt
... where the project is being done, found that the loss of either parent put strain on the child, as the loss of the mother often means loss of the direct carer, while the loss of the father puts the ... fall in profitability and closure of many of the gold mines in the district The economy of the area has been reducing in size over the last few years Central to this is the recession in the mining ... Kopanong given the small towns and distances between them However, despite these problems, there is hope and commitment to improving the lives of OVC and services offered to them The HSRC and NMCF...
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Tài liệu Báo cáo khóa học: Mutations in the hydrophobic core and in the protein–RNA interface affect the packing and stability of icosahedral viruses doc
... found with other dissociated capsid proteins, the lack of elution of the proteins can be explained by non-specific binding of the denatured coat proteins to the gel [34,35] The elution of some D11N ... Structure of the whole capsid of bacteriophage MS2 and of the coat protein dimer bound to RNA (A) The MS2 bacteriophage capsid is colored according to the asymmetric units (B) The coat protein of MS2 ... middle of the central b-strand of the coat protein dimer and its side-chain projects into the protein s interior (Figs 1B and 8) The two Met88 residues are in close proximity to one another at the...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25