the basics of receptor binding and the use of octreotide
Báo cáo khoa học: Analysis of the region for receptor binding and triggering of oligomerization on Bacillus thuringiensis Cry1Aa toxin potx
... mutant toxins and the analysis of their binding activity to the receptor to investigate the role of mutated amino acid residues; (b) the analysis of the influence of the modification of the cysteine ... of the toxin conformation caused by the mutation introduced distant from the receptor- binding site Indeed, mutations in the region distant from the binding site cause unsuspected changes in binding ... FEBS Receptor binding ⁄ oligomerization of Cry1Aa mutants F Obata et al Analysis of the binding ability of synthetic peptides To evaluate the binding capability of the loop regions of Cry1Aa toxins...
- 11
- 588
- 0
Báo cáo y học: " Cellular receptor binding and entry of human papillomavirus" pdf
... not the natural host of HPVs [10] And the consistent results from Evander et al showed that the human laminin, the natural ligand for the a6b4 complex, was capable of blocking the binding of VLPs ... endocytosis was the major cellular entry for many viruses The binding of ligand to a specific receptor is widely recognized to result in the clustering of the ligand -receptor complexes in the coated ... conformational forms, the closed and open, the former the predominant species in solution, from which the binding of the surface receptors cause a transition in the virion to the latter, which might initiate...
- 7
- 328
- 0
Differential global effects of selective estrogen receptor modulators on estrogen receptor binding and transcriptional regulation
... understand the mechanisms of regulation by estrogen receptor and how it is modulated by SERMS This is mainly achieved by eliciting and examining the modulation of the global ER binding sites and the ... to profile ER binding The customised nimblegen array put together all true and putative ER binding sites from various sources The arrays were utilised to profile the ER binding sites and their ... receptor, the receptor dissociates from its cytoplasmic chaperones, the receptor- associated proteins The hormone– Lee Yew Kok PhD Thesis receptor complex then moves to the nucleus, binds to the...
- 214
- 203
- 0
Báo cáo y học: " Potent and persistent antibody responses against the receptor-binding domain of SARS-CoV spike protein in recovered patients" doc
... average ND50 of 0.05 μg/ml (Figure 3B) Discussion The sudden emergence of SARS-CoV shocked the world and impacted the public health seriously The pandemic Figure Neutralization of SARS pseudovirus ... contributions ZLC, LFL, LYD and CZ mainly carried out the experiments and data analysis SBJ, TSL and YXH conceived the studies and wrote the manuscript All authors read and approved the final manuscript ... reported that the average OD values dropped to 0.25 by year and gave a positive rate of 55.56% [35], consistent with the present results Therefore, the clinical application of the viral lysate-based...
- 6
- 267
- 0
Báo cáo y học: " Intrahost variations in the envelope receptor-binding domain (RBD) of HTLV-1 and STLV-1 primary isolates" pot
... samples and corrected the final draft of the manuscript JLB participated to the design of the study, helped with the interpretation of the data and corrected the manuscript MS initiated the project, ... set up the initial design and experiments and participated to the writing of the manuscript ML performed some of the PCR, cloning and sequencing experiments AG and SG provided some of the DNA ... shown to contain the HTLV Env receptor binding domain (RBD) and to direct binding to the glucose transporter GLUT1 shown to be a HTLV-1 and receptor [28,31,32] This binding involves the carboxy terminal...
- 6
- 343
- 0
Refusals to invitations the use of vietnamese learners of english and the use of native speakers of english a comparison
... the reasons or excuses, the Turkish subjects refused a bit less than the others The Turkish and American subjects used pause fillers and then statements of gratitude and appreciation, while the ... that the frequency of the use of the speech act of refusal by the Australian NSs of English was different from that by the VLEs Although the VLEs and the Australian NSs of English employed the ... of the language group and listed in order in a table Then, the similarities and differences of the order of semantic formulas used by the VLEs and the NSEs were analysed For example, E.g Refuser...
- 44
- 1,183
- 4
The Use of Selected Medicinal Herbs for Chemoprevention and Treatment of Cancer, Parkinson’s Disease, Heart Disease, and Depression
... aspects of study design, performance, and analysis, with a focus on randomization of the study subjects, blinding of the investigators and study subjects, and the handling of dropouts and withdrawal ... and Holroyd, 2000), a member of the Hypericaceae family Its yellow flower has been gathered for the feast of St John the Baptist and the word “wort” is the Old English word for plant (Gaster and ... intervals measure the robustness and stability of the estimate of the response rate ratio, and if the confidence interval excludes 1.0, then there is a statistically significant association In the larger...
- 57
- 683
- 0
Tài liệu TREES OF THE NORTHERN UNITED STATES THEIR STUDY, DESCRIPTION AND DETERMINATION FOR THE USE OF SCHOOLS AND PRIVATE STUDENTS doc
... acquainted with all the useful and ornamental woods used in a region; the differences in the color of the heart-wood, the character of the annual layers, and the size and the distribution of the medullary ... The last of the four kinds of parts is found in the center of the flower, and is called the pistil It is this part which forms the fruit and incloses the seed The stamens and the pistil are the ... etc The taste and odor of the bark are characteristics worthy of notice: the strong, fragrant odor of the Spice-bush; the fetid odor of the Papaw; the aromatic taste of the Sweet Birch; the bitter...
- 295
- 569
- 0
Tài liệu THE USE OF STUDENTS AND TRAVELLERS pptx
... settle the soil, they at once laid the bricks upon the surface When the house was finished, the scraps of mortar, the broken bricks, and all the accumulated refuse of the work, made a bed of eight ... fortified their houses, their towns, and the villages upon their domains which commanded either the mountain passes or the narrow parts of the river, against their king or their neighbours The oldest ... Plan of the town of Kahỷn, Twelfth Dynasty Plan of house, Medinet Habỷ, Twentieth Dynasty Plan of house, Medinet Habỷ, Twentieth Dynasty Faỗade of house of Second Theban Period Plan of house of...
- 591
- 394
- 0
Tài liệu The Basics of Social Marketing - How to Use Marketing to Change Behavior docx
... grandmothers as the appropriate source for the intervention The grandmothers who participated in formative research developed the chitterlings cleaning method for their peers Having the grandmothers ... anything we offer is real and true? What is the competition offering? Are we offering something the audience wants more? What is the best time and place to reach members of our audience so that they ... to do, and how it affects the desired change? ® Taken together, will the overall mix of interventions reach enough of the target audience often enough to have the desired impact? ® Is the overall...
- 25
- 605
- 0
Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx
... complex of the pro-peptide and BMP-9 can bind to the type I receptor Alk1 [17], the latencyassociated polypeptide of TGFb inhibits the interaction of TGFb isoforms with type II and III receptors ... pro-peptide of GDF-8 impairs interaction of the mature part with its receptors [16] In the case of BMP-9, the pro-peptide appears not to alter significantly the activity of the mature part [17] For the ... induction of alkaline phosphatase The second binding mode is characterized by ligand binding to pre-formed receptor complexes (PFC), which consist of two type I and two type II receptors By binding of...
- 13
- 892
- 0
Tài liệu Báo cáo khoa học: Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen-related receptor c pptx
... environments of BPA in the ligand -binding pocket of the ERRc The proximity of each amino acid residue (within a ˚ distance of A) to BPA is shown in the boxes depicting the a-helices The portrait ... that of the parent wild-type receptor ERRc Collectively, these results indicated that Arg316 is the most important structural element for the binding of BPA and 4-OHT to the binding pocket of ERRc-LBD ... Given that the roles of these residues definitely confirm each other, the difference in their significance might be attributable to the importance and ⁄ or necessity of the receipt of the phenol-hydroxyl...
- 12
- 583
- 0
Tài liệu Báo cáo khoa học: "Exploring the Use of Linguistic Features in Domain and Genre Classification" potx
... feature selection and evaluation and give a brief description of the algorithms used We then report on the results of the two suites of experiments 5.1 Feature S e l e c t i o n The set of all potential ... (because of this) are especially frequent in texts from law and science, both of which tend to contain texts of argumentative types The frequency of infinitives of auxiliaries reflects both the use ... text The frequencies were standardised using z-scores, so that the resulting random variables have a mean of and a variance of The z-scores were rounded Proceedings of EACL '99 down to the next...
- 8
- 689
- 1
The Use of Mushroom Glucans and Proteoglycans in Cancer Treatment potx
... surgery and long-term chemotherapy By the early 1980s, once more reinforced by the results of Kodama et al,27 the use of PSK as the immuno-component of chemoimmunotherapy consistently doubled the ... retrospective analysis of their success with combined radiation, chemotherapy, and immunotherapy in 133 cases.38 They concluded the addition of immunotherapy to the regimen using either PSK or OK-432 ... none of these criteria for effectiveness was met in a patient at the end of the trial period (six months), the treatment was judged ineffective Once the code was broken at the end of the trial and...
- 24
- 541
- 0
Báo cáo khoa học: Estrogen-related receptor a and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria potx
... lines used here, i.e FTC-133, XTC.UC1 and RO 82 W-1, the expression of PRC and ERRa was correlated with the mitochondrial mass, the expression of mitochondrial genes and the activity of the COX and ... the ERRa– PRC complex is involved in the control of the early phase of the cell cycle This is in accordance with the role played by PRC and ERRa in the transition from the G1 to the S phase of ... with the apparent independence of the mtDNA copy number and expression of the respiratory chain subunits reported by Vercauteren et al [29] They modulated the expression of PRC and found the regulation...
- 13
- 503
- 0
Báo cáo khoa học: The ATPase activities of sulfonylurea receptor 2A and sulfonylurea receptor 2B are influenced by the C-terminal 42 amino acids doc
... nucleotide -binding sites (site and site 2) that comprise the Walker A and Walker B motifs of one NBD and the linker domain of the other In the absence of Mg2+, there is little difference in ATP block of ... the Michaelis–Menten equation using a Km of 460 lM, a Vmax of 2.52 nmol PiÆminÆmg)1 and an offset of 0.1 nmol PiÆminÆmg)1 for SUR2A, and a Km of 41 lM, a Vmax of 0.73nmol PiÆminÆmg)1 and an offset ... part of the catalytic site Thus, these amino acids may interact with the NBDs to modulate binding affinity This interaction appears to require the TMDs of SUR2, as the Km values of NBD2 and the...
- 9
- 620
- 0
Théorie des Fonctions Elliptiques, by Charles Briot and Jean Claude Bouquet This eBook is for the use of anyone anywhere at no cost and with almost no restrictions whatsoever docx
... Andrew D Hwang, Amy Cunningham, Colin Bell, and the Online Distributed Proofreading Team at http://www.pgdp.net (The original copy of this book was generously made available for scanning by the ... copy of this book was generously made available for scanning by the Department of Mathematics at the University of Glasgow.) Ce livre ộlectronique est dộdiộ la mộmoire de Laura Wisewell, notes ... fonction, et, quand la variable a dộcrit une courbe fermộe et que la valeur de la fonction a changộ, dindiquer ce changement par un indice Pour ộtudier la variation de la fonction, quand la variable...
- 636
- 823
- 0
Báo cáo khoa học: The N-terminal hybrid binding domain of RNase HI from Thermotoga maritima is important for substrate binding and Mg2+-dependent activity pot
... significantly changed either in the presence or absence of the metal cofactor By contrast, the substrate binding affinity of the RNase H domain probably increases in the presence of the metal cofactor compared ... on removal of the HBD Binding to substrate To examine whether the HBD of Tma-RNase HI is important for substrate binding, the binding affinities of Tma-RNase HI, Tma-CD and Tma-ND to the 29 bp ... similar to the interaction of the HBD of Hsa-RNase H1 The mutation of Trp43 to Ala greatly reduces both the substrate binding affinities and enzymatic activities of Hsa-RNase H1 [22,26] and mouse RNase...
- 16
- 459
- 0
Democratic Accountability and the Use of Force in International Law docx
... Accountability and the Use of Force in International Law The spread of democracy to a majority of the world’s states and the legitimization of the use of force by multilateral institutions such as NATO and ... reminder that the use of force to destroy is still very much a part of life The instruments of war may have changed and the field of battle been redefined, but the use of force to change the existing ... enter the territory of the state where they operate with the consent of that state, and the number and types of military personnel involved.26 The missions cover a range of uses of military forces...
- 468
- 5,885
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25