t2 relaxation time mapping of articular cartilage at ultra high fields
Báo cáo y học: "Fluvoxamine may prevent onset of psychosis: a case report of a patient at ultra-high risk of psychotic disorde" ppt
... presentation The patient was a 19-year-old Japanese unmarried office worker with no personal or familial history of psychiatric problems On presentation he complained of deterioration of his ... Masaomi Iyo1,3 Department of Psychiatry, Chiba University Graduate School of Medicine, Chiba, Japan Department of Psychiatry, Sodegaura Satsukidai Hospital, Chiba, Japan Division of Clinical Neuroscience, ... defined as patients at ultra- high risk (UHR) of psychotic disorder, from transitioning to psychosis However, the mechanism of such an effect is still unknown Methods: We report the case of a 19-year-old...
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báo cáo hóa học:" Study of the collagen structure in the superficial zone and physiological state of articular cartilage using a 3D confocal imaging technique" pptx
... magnifications at a field view of 50 μm × 50 μm (low magnification) and 33 μm × 33 μm (high magnification) are used in this study to produce optimal observations of the collagen orientation Using ... prevention of the initial lesion of AC surface and increase of the durability of the AC This is consistent with the fact that loss of the most superficial layer of AC accelerates worn off AC [13] ... chondrocytes near the articular surface to the joint cavity, Fig 2(F) In spite of increase of age, approximately 50% of the cartilage specimens demonstrate little surface disruption (approximate ICRS grade...
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Báo cáo hóa học: " Research Article A Note on the Relaxation-Time Limit of the Isothermal Euler Equations" pdf
... “Systems of equations of hyperbolic-parabolic type with applications to the discrete Boltzmann equation,” Hokkaido Mathematical Journal, vol 14, no 2, pp 249–275, 1985 Jiang Xu: Department of Mathematics, ... independent of τ,T,U Proof The proof of Proposition 4.1 is divided into two steps First, we estimate the L∞ ([0,T],H σ+ε ) norm of U, and the L2 ([0,T],H σ+ε ) one of u Then, we estimate the L2 ... limit of the multidimensional isothermal Euler equations,” Transactions of the American Mathematical Society, vol 359, no 2, pp 637–648, 2007 [2] S Junca and M Rascle, “Strong relaxation of the...
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Báo cáo y học: "More intrinsic parameters should be used in assessing degeneration of articular cartilage with quantitative ultrasound" doc
... Measurement of depth-dependence and anisotropy of ultrasound speed of bovine articular cartilage in vitro Ultrasound Med Biol 2004, 30:953-963 Suh JK, Youn I, Fu FH: An in situ calibration of an ultrasound ... quantitation of superficial degradation of articular cartilage Ultrasound Med Biol 2004, 30:783-792 Zheng YP, Mak AF: An ultrasound indentation system for biomechanical properties assessment of soft tissues ... evaluation of articular cartilage degeneration using a novel ultrasound water jet indentation system Ann Biomed Eng 2008 Nov 15 [Epub ahead of print] Zheng YP, Mak AF, Lau KP, Qin L: An ultrasonic...
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Báo cáo y học: "Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis" pptx
... aliquots of cDNA were amplified by PCR, with initial denaturation at 94°C for min, followed by cycles of 30 s of denaturation at 94°C, 30 s annealing at variable primer specific temperatures (Table ... number of samples evaluated However, the standard deviation of the MTP samples was similar to that of the LTP, suggesting that the lower number of MTPs studied did not contribute to the lack of statistical ... highly differentiated cells of cartilage, are responsible for maintaining a homeostatic balance between production and degradation of cartilage ECM [14,15] The metabolic status of the chondrocyte...
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Báo cáo y học: " Major biological obstacles for persistent cell-based regeneration of articular cartilage" pps
... different aspects of transplant integration with cartilage and bone have to be appreciated With respect to integration of cartilage with cartilage, the nature and status of the tissue that comprises ... Although the fabrication of neocartilage with an appropriate zonal organization has been attempted [204,205], exact reproduction of the different zones of native articular cartilage, including ... challenges associated with cellbased cartilage repair procedures is integration of the graft tissue with the host Depending on the nature of the cartilage Page of 15 (page number not for citation purposes)...
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Báo cáo y học: "Bonding of articular cartilage using a combination of biochemical degradation and surface cross-linking" pdf
... transplantation The objective of this study was to investigate the initiation of immediate bonding of articular cartilage blocks by means of combining cartilage degradation and cross-linking reagents ... combination with degrading pre-treatment The combinations of EDC/NHS Page of 11 (page number not for citation purposes) Transglutaminase, a naturally occurring enzyme in articular cartilage, catalyses ... Biomechanics of integrative cartilage repair Osteoarthritis Cartilage 1999, 7:29-40 McGowan KB, Sah RL: Treatment of cartilage with beta-aminopropionitrile accelerates subsequent collagen maturation...
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Báo cáo y học: "Ultrasound properties of articular cartilage in the tibio-femoral joint in knee osteoarthritis: relation to clinical assessment (International Cartilage Repair Society grade)" pptx
... cartilage at site B was greater than that at site E (Figure 4) Cartilage at site B is located on the lateral condyle, and site E cartilage is located on the lateral tibial plateau exposed by the lateral ... evaluation Before ultrasound evaluation, cartilage at the seven sites was evaluated macroscopically using the ICRS articular cartilage Figure Anatomical location of the knee Site A, femoral lateral ... between signals of grade cartilage was significantly less than that of grade cartilage (Figure 3e), but that of grade cartilage and grade cartilage did not differ from that of grade cartilage Although...
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Báo cáo y học: "Role of hypoxia-inducible factor 1alpha in the integrity of articular cartilage in murine knee joints" potx
... massive degenerative changes culminating in a complete loss of articular cartilage tissue and degeneration of the menisci The cartilage of the lateral compartment and the patellofemoral joint ... The formation of osteophytes was present at the margins of the articular surface in all joint compartments The articular cartilage showed signs of degeneration, with fissuring and loss of superficial ... destruction of Page 10 of 12 (page number not for citation purposes) the articular cartilage differed between DMOG-treated joints and control joints Degeneration of the articular cartilage and...
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Báo cáo y học: "More intrinsic parameters should be used in assessing degeneration of articular cartilage with quantitative ultrasound" ppt
... Measurement of depth-dependence and anisotropy of ultrasound speed of bovine articular cartilage in vitro Ultrasound Med Biol 2004, 30:953-963 Suh JK, Youn I, Fu FH: An in situ calibration of an ultrasound ... quantitation of superficial degradation of articular cartilage Ultrasound Med Biol 2004, 30:783-792 Zheng YP, Mak AF: An ultrasound indentation system for biomechanical properties assessment of soft tissues ... evaluation of articular cartilage degeneration using a novel ultrasound water jet indentation system Ann Biomed Eng 2008 Nov 15 [Epub ahead of print] Zheng YP, Mak AF, Lau KP, Qin L: An ultrasonic...
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Báo cáo y học: "Ultrasound has the potential to detect degeneration of articular cartilage clinically, even if the information is obtained from an indirect measurement of intrinsic physical characteristics" pdf
... Ikeuchi K, Tsutsumi S, Nakamura T: Estimation of the mechanical property of meniscus using ultrasound: examinations of native meniscus and effects of enzymatic digestion J Orthop Res 2007, 25:884-893 ... Mori K, Hattori K, Habata T, Yamaoka S, Aoki H, Morita Y, Takakura Y, Tomita N, Ikeuchi K: Measurement of the mechanical properties of regenerated articular cartilage using wavelet transformation ... Vol 11 No Kuroki et al that the ultrasound information our technique provides will help clinicians to understand degeneration of articular cartilage – even if the information is obtained from an...
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Báo cáo y học: "Prostaglandin E2 receptor type 2-selective agonist prevents the degeneration of articular cartilage in rabbit knees with traumatic instability" pptx
... intra -articular administration of gelatin hydrogel containing 0, 80, and 400µg of the specific EP2 agonist, ONO-8815Ly, respectively) Degeneration of the articular cartilage was evaluated at or ... at the concentration of 0.1 µM Discussion The effect of PGE2 on the progression of OA is still a matter of debate In some reports, PGE2 was shown to destroy articular cartilage by degrading cartilage ... defects The purpose of the current study is to analyze the effect of this agonist on articular cartilage in a model of traumatic degeneration Methods: The model of traumatic degeneration was established...
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Tài liệu Báo cáo khoa học: Hypoxic resistance to articular chondrocyte apoptosis – a possible mechanism of maintaining homeostasis of normal articular cartilage pdf
... of OA and may be beneficial in the detection of patients at risk of rapidly progressing disease Articular cartilage is an avascular tissue that functions at an oxygen tension lower than that of ... inhibition of cartilage and chondrocyte degeneration Results Macroscopic and radiographic examination of the articular cartilage after experimentally induced OA Articular cartilage of the femoral ... combined treatment with ALLN and TRAIL caused a significant dissipation of MTP relative to negative controls When ROS generation was examined, the results showed that pretreatment of the cells...
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Taxation of European Companies at the Time of Establishment and Restructuring docx
... Christiane Malke Taxation of European Companies at the Time of Establishment and Restructuring GABLER RESEARCH Christiane Malke Taxation of European Companies at the Time of Establishment and ... examination 1.3 Organization of the thesis Relevance of the European Company in practice 2.1 Basic features of the European Company 2.2 Examination of statistical data ... practice 13 ber states which had not transposed the directive in time. 53 When looking at the ratio of SEs and the population of the member states,54 the rather small member state Luxembourg is...
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báo cáo hóa học:" Fourier-transform infrared anisotropy in cross and parallel sections of tendon and articular cartilage" pptx
... transitional moments of one pair of amide bonds at one location in the triple helix (a) The transitional moments of one pair of amide bonds at one location in the triple helix The distribution of numerous ... small concentration of connecting fibrils in cartilage' s radial zone [27] Further experiments have been planned to investigate the nature of the 3D fibril orientation in articular cartilage Conclusion ... experiments were repeated at these three orientations Figure shows the anisotropy profiles of amide I and amide II for these three orientations It is clear that both amide vibrations have distinct...
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Báo cáo hóa học: " Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed β-propeller domain of the HIV-1 cellular interactor EED" pptx
... host chromatin At the late steps of the virus replication cycle, we found that overexpression of isoforms EED3 and EED4 had a significant negative effect on virus production, and that virus assembly ... 29.2 Figure Crystallogenesis of histidine-tagged isoform of EED Crystallogenesis of histidine-tagged isoform of EED (A), Platelet-like crystals of EED3-H6 protein of 441 residues, obtained in ... 2-Methyl-2,4-pentanediol (MPD) at a temperature of 292 K A 1:1 ratio of protein to reservoir solution was used Protein purification Isolation of His-tagged proteins from bacterial cell lysates was carried...
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Báo cáo y học: "Differential recovery of glycosaminoglycan after IL-1-induced degradation of bovine articular cartilage depends on degree of degradation" pot
... spatial information because the destructive nature of the [GAG] measurements required that time course information be inferred from averages of separate animals/samples harvested at different time ... at a given time point was computed as the mean [GAG] calculated across all cartilage- containing pixels of the image The rate of [GAG] accumulation (i.e the tissue’s recovery rate) was calculated ... of the capacity of cartilage to repair osteoarthritis-like degradation The rate of GAG replenishment observed in this study compares well with published synthesis data Using sulfate incorporation...
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Báo cáo y học: "α Does protein kinase R mediate TNF-α- and ceramide-induced increases in expression and activation of matrix metalloproteinases in articular cartilage by a novel mechanism" pps
... up-regulation of PACT at the onset of osteoarthritis [15], we investigated whether PKR mediates TNF-α-induced degradative pathways in chondrocytes Our data demonstrate that TNF-α treatment of bovine ... PKR that may be important in cartilage degradation Others have shown that ceramide stimulates aggrecanase-mediated degradation of proteoglycans in articular cartilage, but the mechanism of action ... potential role of PKR in cartilage degradation Results from the current study have led us to hypothesise that TNF-α-induced degradative pathways in cartilage may be mediated via activation of PKR TNF-α...
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Báo cáo y học: "Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury" potx
... embryonic tissues indicate that the activation of the canonical β catenin pathway plays an important role in joint specification [30,42] and in the regulation of chondrocyte differentiation inhibiting ... explants treated with NaCl (Figure 6c,d) To test the effects of the activation of the canonical WNT pathway in adult human articular cartilage, we determined the expression of the cartilage markers ... a response of the articular cartilage to different types of injuries In addition to the upregulation of BMP-2 mRNA, we have documented a consistent injury-associated down-regulation of the secreted...
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Báo cáo y học: "Reactive oxygen species induce expression of vascular endothelial growth factor in chondrocytes and human articular cartilage explants" pps
... annealing at a temperature of 60°C for 30 seconds, elongation at 72°C (the elongation time depended on the size of the fragment, that is the number of bp divided by 25 yielded the time in seconds) ... with 100 ng of total RNA in an i-Cycler (Biorad, Munich, Germany) The temperature profile included an initial denaturation for 15 minutes at 95°C, followed by 37 cycles of denaturation at 95°C for ... promotes catabolic pathways in the cartilage itself, thereby leading to a progressive breakdown of the ECM of articular cartilage Recent investigations have revealed the participation of free radicals...
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