... CPB was instituted with a perfusion index of 2.7 l/min/m of body surface area Hypothermia was obtained by cooling the priming solution within the extracorporeal circuit and the circulating blood ... development of junctional arrhythmias, as indicated by the increased risk for junctional tachycardias following interventions that were remote from the atrioventricular node (including resection of subaortic ... postoperative arrhythmias following cardiopulmonary bypass (CPB), using continuous dual lead Holter monitoring We also aimed to examine whether certain surgical procedures present riskfactors for specific...
... HIFa activity by regulating protein–protein interactions; hydroxyproline provides a docking site for VHL binding while hydroxyasparagine prevents binding of the coactivator p300 Finally, the long ... 2-His1-carboxylate motif (His-X-Asp/Glu…His), responsible for coordinating the binding of the iron atom [92] By using a combination of protein database mining, and genetic and biochemical assays, three novel ... hydroxylase inhibitor dimethyloxalylglycine (DMOG), or iron antagonists, when the putative FIH-1 binding region is removed [89] A region spanning the FIH-1 binding site in HIF-1a contains an arginine-dileucine...
... transferring eIF4E to the nucleus: this again involves a binding site on eIF4E that is occluded by 4E-BP1 A number of agents increase the phosphorylation of 4E-BP1 including amino acids and insulin ... but without a rise in plasma insulin concentration [35] This again underlines the primary role of leucine in regulating protein synthesis In mice with defective insulin signalling (with similarities ... Regulation of protein kinase B and glycogen synthase kinase by insulin and b-adrenergic agonists in rat epididymal fat cells Activation of protein kinase B by wortmannin-sensitive and-insensitive...
... residential settings which could explain this trend [8] This conclusion reinforces the importance of preventing initial MRSA colonisation in this high riskgroupby judicious use of prophylactic ... ‘bug-bear’ of a surgical practice: reducing the incidence of MRSA surgical site infections Annals of the Royal College of Surgeons of England 2006, 88(2):222-3 Gray JW, George RH: Is the incidence of ... Francesc Marco, Martinez JA, et al: “Influence of Vancomycin Minimum Inhibitory Concentration on the Treatment of MethicillinResistant Staphylococcus aureus Bacteremia” Clinical Infectious Diseases...
... distribution by high risk groups High risk groups were those who were at higher riskof suffering from severe condition, complication that could result in die of the disease of interest According to WHO, ... association between some factors and riskof getting infection with pH1N1/2009 (univariate analysis) Infected by Non-infected by 2009 pandemic 2009 pandemic OR Riskfactors influenza influenza (95% CI) ... occur in the elderly group 5 1.3.2 Riskfactors and high -risk groups Currently, there is not much research related to identifying riskfactors for influenza infections, especially for influenza...
... implementation of the CCM and communication among staff and clinicians; and 3) to advance the science of translational research in primary care settings by examining the sustainability of the intervention ... auditor who is blinded to assignment of clinics to intervention or control groups The abstraction will take place at baseline, after the conclusion of the delayed intervention in the control clinics ... trial with 20 clinics in the intervention arm and 20 in the control arm (see Additional File 1) Because the intervention will be implemented in groups of five clinics at three-month intervals, a...
... predominantly in immunosuppressed patients [2] Asymptomatic shedding of HSV in healthy individuals has been reported to occur in 2–10% of infected individuals [4,5] HSV-1 can be detected in the ... TW participated in the interpretation of data and drafting of the manuscript TFS participated in the study design, interpretation of the data and drafting of the manuscript FM initiated the study, ... molecular typing Sequencing of the hypervariable region of the viral glycoprotein G revealed that patients' viruses fell into two groups, with viral sequences of patients C2 and C3 grouping together...
... more binding sites; of these approximately 180 composite elements, 15 are synergistic combinations of homotypic TFs Interestingly, of these known combinations are in the 51 selected TFs, including ... distance of 20 bp Also listed are the numbers of conserved E2F1 binding site(s) detected by phylogenetic footprinting (PF) Asterisks indicate promoters of genes with experimentally proven E2F1 binding ... alignment, our approach of enriching TFBS combinations involved first obtaining all potential TFBSs on a genome-scale and then looking for TFBS combinations based on the pattern of binding site arrangement...
... than log10 inactivation was achieved within a UV dose of mJ/cm2 in both suspending media Also, it appears that the extent and kinetics of inactivation of G lamblia cysts by LP UV in both media ... more effective – in inactivating G lamblia cysts in real field waters Meanwhile, the inactivation kinetics of G lamblia cysts by MP UV in this study is somewhat faster than those in previous studies ... number of Giardia lamblia cysts dosed into each animal 2: Infectivity Response is the number of animals with living stages of Giardia present/total number of animals infected The results of this...
... rate of HIV coinfection in many of the studies, ranging from 26% in Tanzania to 73% in Malawi [7,8] Generally, the prevalenceof TB in SSA prisons is estimated to be 6–30 times higher than that in ... distribution of TB against duration of cough, timing of cough occurrence, history of Table TB positivity as detected by LED microscopy among different socio-demographic factorsof prison inmates in North ... periodic surveillance of TB and quarantine of the inmates with TB and linking them to the nearby public health institutions Health education for inmates so as to reduce delay in seeking TB diagnosis...
... trade fell in twelve, rose in eight and remained stable in Finland The largest decreases were observed in Romania (-3.2%), Spain (-2.2%) and Slovenia (-2.1%), and the highest increases in Luxembourg ... Monthly comparison In December 2012, compared with November 2012, “Food, drinks and tobacco” fell by 0.8% in the euro area and by 0.6% in the EU27 The non-food sector declined by 1.0% and 0.7% ... Annual comparison In December 2012, compared with December 2011, “Food, drinks and tobacco” fell by 2.1% in the euro area and by 1.8% in the EU27 The non-food sector dropped by 4.2% and 1.7% respectively...
... participating countries byWHO region and byincomegroup level As indicated in the table, 13 are low -income countries (LICs), 24 are lower-middle -income countries (LMICs), and are upper-middle -income ... availability of medicines in primary care show an increase byincome level, suggesting a greater integration of mental health into primary care at higher income levels Only 15% of the participating LICs ... absent in almost all the participating countries of the Eastern Mediterranean (2%) Table 2.1 Summaryof outpatient facility indicators, by country incomegroup (median) Incomegroup Number of facilities...
... observed by doctors in the DOTS clinics during the diagnosis of childhood pulmonary TB Weight gain was usually, seen to be the first indication of recovery during treatment This finding underlines ... the diagnosis of pulmonary tuberculosis in resource poor and TB endemic setting where the TB case finding has become problematic The pattern of ranking of symptoms by those working in DOTS centre ... caused by the presence of nontuberculous mycobacteria species, routine BCG vaccine to children and poor reaction to tuberculoprotein in malnourished children in this setting The finding in this...
... demonstration of intracellular transglutaminase-catalyzed protein cross-linking in vivo Experimental procedures Collection of sperm Specimens of A pectinifera were collected, during their breeding season, ... transglutaminase Occurrence of transglutaminase in sperm chromatin We next examined whether nuclear transglutaminase is present in the chromatin fraction by carrying out an immunoblot analysis using ... H4 of an adjacent nucleosome core Incorporation of DCA into histones We next addressed the issue of whether transglutaminase is involved in the formation of an Ne(c-glutamyl)lysine bridge of...
... detected in an individual of the Uygur ethnic minority We did not find the 309-kb deletion of GJB6 in any of the 212 patients with monoallelic GJB2 coding region mutation or in any of the 105 ... 10.8%(767/7133) of the 7133 nonsyndromic hearing loss patients is postlingual and in 89.2% (6366/ 7133) is preligual The percent of postlingual hearing loss in the 212 nonsyndromic hearing loss patients group ... mutation in the coding region of GJB2 is 6.6%(14/212) and that of preligual is 93.4% (198/212) The percent of postlingual hearing loss in the 262 nonsyndromic hearing loss patients group without...
... however, studies in South Africa had found a higher rate of HIV infection among women who migrate to urban settings.[6] US-MEXICO BORDER We believe that our finding of high HIV seroprevalence among ... preventive interventions throughout Mexico Further research is needed in other at risk populations in Tijuana and other border cities throughout the US-Mexico border Funding Information Figure Map of ... Information Figure Map of Mexico Map of Mexico States of origin of migrating pregnant women, Tijuana General Hospital 2003 indicates Baja California; 2, Sinaloa; 3, Jalisco; 4, Michoacan; and...
... (Fig 5) Examining the sensitivity in uncertainty of the BEF by ignoring the uncertainty in stand age increased the error in young and old age-classes Having the uncertainty in stand age included ... work of Laasasenaho [10], who derived RSEs of 7–8% for prediction of stem volume of Scots pine, Pinus sylvestris L in Finland with selected values of D and H Each simulation round was started by ... Impact of different sources of uncertainty on the overall uncertainty of BEFs, when 60% of the intraplot variance is fixed (residual errors of model predictions) In default, all sources of uncertainties...