sulfur in the alleviation of cadmium induced oxidative stress in plants
Báo cáo khoa học: Cyclosporin A-induced oxidative stress is not the consequence of an increase in mitochondrial membrane potential doc
... Cyclosporin A -induced oxidative stress M van der Toorn et al calcineurin therefore play a role in cyclosporin A -induced oxidative stress and disturbed Ca2+ homeostasis ... concentrations of CsA and its analogs on the Ca2+-dependent induction of opening of the MPTP The data are representative of four experiments A concentration of mM Ca2+ was used to induce opening of the ... P-glycoprotein Unlike CsA, both NIM811 and PSC833 not inhibit calcineurin Together, these results suggest that neither mitochondria, inhibition of calcineurin nor blockage of P-glycoprotein play a role in...
- 10
- 455
- 0
Báo cáo khoa học: Inhibition of PI3K/Akt partially leads to the inhibition of PrPC-induced drug resistance in gastric cancer cells pdf
... indicate that inhibition of the PI3K/Akt signaling pathway may lead to inhibition of the MDR induced by PrPC in gastric cancer cells The mechanism underlying PI3K/Akt-mediated PrPC -induced MDR in gastric ... immunoreactivity (IR) The staining was semiquantitatively evaluated by assigning a score for the intensity of the IR and for the proportion of cells positively stained The intensity of IR (intensity score) ... PrPC -induced MDR in gastric cancer cells, partly by decreasing the transcriptional activation of P-gp Continuing from our previous work, it further reveals the function of PrPC in the MDR of cancers...
- 10
- 448
- 0
Báo cáo khoa học: Photodynamic treatment and H2O2-induced oxidative stress result in different patterns of cellular protein oxidation ppt
... Matching the blot with the protein map shows that PDT caused labeling of a-tubulin and b-tubulin (spots and 2) The minor spot probably reflects labeling of a small fraction of actin The rest of the ... fingerprints of trypsin digests of the spots of interest obtained with MALDI-TOF, followed by a database search with the Mascot software for peptide mapping result) and matching of our protein maps ... accumulate in the cell Irradiation of rat fibroblasts, loaded with both Hypocrellin A and acetylTyr-Fluo, resulted in the labeling of cellular proteins, as shown in Fig PDT -induced protein labeling was...
- 7
- 292
- 0
Báo cáo khoa học: "Comparative study of PM2.5 - and PM10 - induced oxidative stress in rat lung epithelial cells" pptx
... Western Blotting The lower shows the ratio of Nrf2/actin using calculatging by densitometor In the cell treated with PM2.5, the level of Nrf2 was much highly increased than in the cell treated ... PM10 to oxidative stress repair enzyme, we used RT-PCR analysis Figure shows the expression level of catalase mRNA induced by Comparative study of PM2.5 - and PM10 - induced oxidative stress in rat ... suggesting that PM2.5 induced more oxidative stress than PM10 In the single strand breakage assay using pBR322 DNA, the ratio of changed form II/total plasmid DNA (form Comparative study of PM2.5...
- 8
- 442
- 1
Báo cáo y học: "Role of Leukotriene Receptor Antagonists in the Treatment of Exercise-Induced Bronchoconstriction: A Review" pot
... discussion of the mediators involved in EIB and their cellular sources are beyond the scope of this review.) 61 activity in individuals with underlying airway hyperresponsiveness.4 The occurrence of ... for the treatment of EIB.12 Results are varied; routine use of these types of pharmacologic intervention is not recommended as primary treatment of EIB.12 Other therapies are still being investigated.12 ... expiratory volume in second LTRA administration Another group reproduced these findings by showing similar protection against EIB during the first days of treatment with either montelukast or...
- 5
- 663
- 0
Báo cáo khoa học: "SemiPro-inflammatory cytokines play a key role in the development of radiotherapy-induced gastrointestinal mucositis" pptx
... general, there was weak-moderate IL-1b staining in the jejunal crypts There was predominantly weak staining of the villi The intensity of IL-1b staining fluctuated throughout six weeks of radiotherapy ... in the intestinal epithelium of rats receiving radiotherapy Previous research into expression at the protein level has shown conflicting findings In one study, proinflammatory cytokine protein ... later time points of radiotherapy suggesting that these cytokines can ultimately induce more tissue injury and inflammation in the intestine with increasing total doses of radiotherapy Expression...
- 8
- 335
- 0
Báo cáo khoa học: "The use of caspase inhibitors in pulsed-field gel electrophoresis may improve the estimation of radiation-induced DNA repair and apoptosis" pdf
... efficiently determine rejoining without the inference of the apoptosis Figure illustrates the effect of abrogating apoptosis in NP18 cells from a xenograft, showing clear differences between initial and ... were seen in the NP18 cell line (data not shown) In sharp contrast, in irradiated cell-plugs the initial DNA extraction was higher than in unirradiated cell-plugs indicating that radiation -induced ... environment (Figure 2B) To further confirm that the origin of apoptosis was the encapsulation in agarose, we investigated the activation of caspase-3 in cells growing as monolayer (in a physiological environment)...
- 8
- 469
- 0
báo cáo khoa học: " High resolution melting analysis for the detection of EMS induced mutations in wheat SbeIIa genes" doc
... SBEIIa-D(A201T) the amino acid change induced by the EMS treatment is located in the region of the N-terminal domain of the glycogen branching enzyme family, reported to be essential for the size of the ... product showed the inclusion of the intron V, whereas the smaller one was found to contain a deletion of the first seven nucleotides of exon VI The presence of the intron V in the longer transcript ... caused the loss of two of the seven amino acids involved in the binding and catalytic activity in normal SBEIIa protein, respectively Arg465 and Asp467 Analysis of SBEIIa-transcripts in the knock...
- 14
- 487
- 0
Báo cáo y học: "New insights into the pathogenesis of glucocorticoid-induced avascular necrosis: microarray analysis of gene expression in a rat model" potx
... than other endothelial cells in the body In keeping with the theory of endothelial cell activation having a role in ANFH, coagulation-related gene expression in particular serine (or cysteine) ... development of early steroid -induced ANFH Determination of whether A2M over-expression in our study is either the result or the cause of the apoptosis found in our rats developing early ANFH following ... apoptosis is involved in the early stages of steroid -induced osteone- crosis [26] Weinstein et al reported that the number of apoptotic bone cells increased significantly in mice after steroid administration...
- 12
- 312
- 0
Báo cáo y học: "Further cautions for the use of ventilatory-induced changes in arterial pressures to predict volume" docx
... but these swings should be minimally responsive to volume infusion because they are minimally related to right heart filling Based on the above analysis, how can the poor predictive values of PPV ... change in stroke volume The use of percentage change could thus have obscured what was happening, especially considering that there were progressive increases in the stroke volumes Two other factors ... might be involved First, dUp probably accounted for a significant part of the PPV dUp is related to the decrease in afterload with a positive pressure breath and the squeezing of blood out of the lungs...
- 2
- 220
- 0
Effects of anti malaria drug artesunate in the treatment of rhinovirus induced asthma exacerbation
... have been shown to be the binding sites of the receptors and thus block the binding of the neutralizing binding sites of antibodies (Kim, Smith et al 1989) Blockage of the binding site with several ... control the symptoms None of them are able to eliminate the disease The major unmet in this area include better management of the severe forms of the disease and development of curative therapies Therefore, ... reduced the binding activity of NF-κB Artesunate attenuated the exacerbation of RV on asthma, and our findings implicated a potential value of artesunate in the treatment of rhinovirus-induced...
- 172
- 712
- 0
The influence of the xin repeat containing proteins on the development of pressure induced cardiac hypertrophy in mice
... Xin repeat-containing proteins as part of the cardiac cytoskeleton As the function of the Xin repeat-containing proteins (XIRPs) in the heart will be in the center of this study, their role in ... to the elastic properties of the sarcomere In the center of the sarcomere the myosin filaments are connected by the proteins of the M-band (M) e.g myomesin and M-protein The region in which the ... proteins XIRP1 Xin repeat containing protein XIRP2 Xin repeat containing protein Introduction 1.1 The heart - an overview 1.1.1 Physiological function of the heart The function of the heart is to...
- 148
- 466
- 0
Báo cáo khoa học: Fasting-induced oxidative stress in very long chain acyl-CoA dehydrogenase-deficient mice pdf
... mice (Fig 3A) Interestingly, the MCT diet also induced AOX gene expression in WT mice After 24 h of fasting, both genotypes showed a significant increase in the expression of AOX with the MCT diet ... approval of the Heinrich-Heine-University Institutional Animal Care and Use Committee The care of the animals was in accordance with the Heinrich-Heine-University Medical Center and Institutional ... observed in human VLCADD [5] In fact, in both mice and humans, clinical symptoms become mainly evident as a consequence of triggers such as fasting, resulting in the accumulation of long-chain acylcarnitines,...
- 10
- 381
- 0
Báo cáo khoa học: Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice pdf
... at and months of age, representing the early stage of DCM (data not shown); therefore, we propose that the up-regulated expression of CYP2E1 was involved in the pathogenesis of DCM in cTNTR141W ... longitudinal sections are shown in (A) (magnification ·20; scale bars = mm) The hemotoxylin and eosin-stained sections of the left ventricle are shown in (B) and Masson’s trichrome stained sections of ... observations made in rat liver [21] The expression of CYP2E1 is increased in the human ischemic and dilated heart [12] and in left ventricular tissue of the spontaneously hypertensive rats [13] In the present...
- 9
- 404
- 0
Báo cáo hóa học: "The toxicity of cadmium and resulting hazards for human health" ppt
... by the skin: binding of a free cadmium ion to sulfhydryl radicals of cysteine in epidermal keratins, or an induction and complexing with metallothionein [15] Handling Of cadmium in the body Once ... transporting complexes, endocytosis of proteins Cd-MT, Cd-Protein Figure Handling of cadmium in human body Handling of cadmium in human body Figure legend text: Metabolism, storage and excretion of cadmium ... by the blood, the majority of cadmium is transported bound to proteins, such as Albumin and Metallothionein The first organ reached after uptake into the GI-blood is the liver Here cadmium induces...
- 6
- 736
- 0
Báo cáo hóa học: "Biocompatible micro-sized cell culture chamber for the detection of nanoparticle-induced IL8 promoter activity on a small cell population" pot
... allows quantification of the fluorescence intensity and thus the inflammatory status of single cells The determination of the effect of miniaturization on nanoparticle -induced inflammatory cell responses ... Quantification of pIL8-GFP induction For quantification of an induced inflammatory reaction, the reporter cells pIL8-GFP A549 were used The induction of the promoter is linked to the production of the inflammatory ... in the microcavity One advantage of the miniaturized method is the recording of the complete cell culture area in one image Hence, every individual cell response is involved in the assessment of...
- 14
- 632
- 0
Báo cáo lâm nghiệp: "An integrated analysis of 33 Eucalyptus trials linking the onset of competition-induced tree growth suppression with management, physiographic and climatic factors" pptx
... barrier, reducing the rate of seed germination thereby delaying the onset of inter-specific competition The interaction between the site related variables (PC1 and 2) and method of site preparation ... Description of the 33 trial sites included in the multivariate analyses to link physiographic, climatic and site management factors to weed -induced Eucalyptus suppression in South Africa Competition -induced ... DISCUSSION The results of the PCA and multiple linear regression analyses indicated that there were variables in the data set that could be used to estimate the time at which competition-induced...
- 7
- 372
- 0
Báo cáo khoa học: " Effect of dihydrotestosterone on mouse embryonic stem cells exposed to H2O2-induced oxidative stress" pdf
... attenuate the activation of MAPKs signaling [29,58], thereby indicating that the MAPK signaling pathway is an important target of ROS The levels of intracellular ROS were increased as the result of the ... H2O2 to investigate the mechanisms of cell injury resulting from acute oxidative stress in various cells and tissues [18,59] Therefore, the purpose of this study was to determine the effect of DHT ... which supports the role of DHT in this process In addition, H2O2 activated NF-κB is one of the key regulatory molecules in oxidative stress -induced cell injury and the activation of NF-κB has an...
- 10
- 263
- 0
Báo cáo y học: "THR0921, a novel peroxisome proliferator-activated receptor gamma agonist, reduces the severity of collagen-induced arthritis" pps
... from the bark of plants of the Pterocarpus genus Plant extracts from this origin have long been used in the Indian Ayurvedic system of medicine [20,21] Given the potential role of PPARγ in inflammatory ... production of TNF-α, IL-1β, and INF-γ from isolated spleen cells induced by LPS As the involvement of each of these cytokines in the pathogenesis of arthritis is well Available online http://arthritis-research.com/content/8/1/R7 ... a critical role in the pathogenesis of RA, we monitored the production of the proinfammatory cytokines TNF-α, IL-1β, and INF-γ as well as anti-inflammatory IL-4 and IL-10 in the spleen cell supernatants...
- 8
- 339
- 0
Báo cáo y học: "Morphological characterization of intra-articular HMGB1 expression during the course of collagen-induced arthritis" docx
... cells Original magnification ×800 of clinical disease In addition, at the time point of arthritis onset, a substantial number of the infiltrating inflammatory cells expressed HMGB1 in their cytoplasm, ... scores of the cytokine expression appeared to be very similar within the group with reproducible results in at least three staining experiments A substantial number of the first infiltrating inflammatory ... bone (Figure 3) At these time points, the number of TNF-expressing cells dominated quantitatively throughout the synovial tissue, the most abundant expression being within the lining layer Both spatial...
- 10
- 265
- 0
Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25