study of the anti photoaging effect of noni morinda citrifolia
Báo cáo y học: "The PI3K–NF-κB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis" pdf
... inflammation was induced, thus confirming the role of adenosine and of the A3AR in the regulation of the anti- inflammatory response [13] The A3AR belongs to the family of the Gi-protein-associated cell ... BN: Reversal of the antiinflammatory effects of methotrexate by the nonselective adenosine receptor antagonists theophylline and caffeine: evidence that the antiinflammatory effects of methotrexate ... arthritis Effect of IB-MECA in themanifestations absence of MRS 1220 on the clinical and pathological manifestations of adjuvant-induced arthritis (a) Effect of IB-MECA on the pathological features of...
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Báo cáo y học: "Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A3 adenosine receptor expression" doc
... compared with the control group and each of the other treatment groups (Figure 1a) In the therapeutic treatment study, in which all of the treatments were initiated at the onset of disease, clinical ... explore the mechanism underlying the efficacy of the combined treatment, we first examined the mode of action of MTX It acts as an antagonist of folic acid, subsequently inhibiting the synthesis of ... chain of events results in intracellular accumulation of adenosine, which is then released into the extracellular environment [19] The working hypothesis of the present study was that the increase...
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Báo cáo y học: "Transcriptional regulation of matrix metalloproteinase-1 and collagen 1A2 explains the anti-fibrotic effect exerted by proteasome inhibition in human dermal fibroblasts" docx
... conclusion, the effect of PI dominates the influence of TGF-β in controlling the binding of both SP1 to COL1A2 and c-Jun to MMP-1 Discussion The major finding of our work is that the overall antifibrotic ... binding of c-Jun to the AP-1 site in the promoter of MMP-9 This may be due to the influence of sequences adjacent to the AP-1 site or to the composition of the AP-1 complex that binds there, and ... whether the inhibitory effect of PI on SP1 binding to COL1A1 could be due to its effects on Smad2 signaling We therefore studied the fate of Smad2 in fibroblasts cultured in the presence of TGF-β...
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Báo cáo y học: " Inhibition of SOC/Ca2+/NFAT pathway is involved in the anti-proliferative effect of sildenafil on pulmonary artery smooth muscle cells" pps
... Results were quantified by densitometry, and the densities of immunoblotting were analyzed by scanning X-ray film with Quantitative One software The value of the relative density of the TRPC1 band ... normalized to the density of the β-actin band to Page of 14 (page number not for citation purposes) Respiratory Research 2009, 10:123 represent the amount of TRPC1 protein The ratio of normoxia ... hyperpolarization, all of which contributed to remodeling of the pulmonary artery [13] The present study further demonstrates that hypoxia induces NFAT nuclear translocation via the up-regulation of TRPC1,...
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A study on the anti tumor activity of LY303511, an inactive analogue of a p13k inhibitor, LY294002
... demonstrated the inhibitory effect of other types of ROS on receptor mediated apoptosis The superoxide anion has been implicated in the prevention of CD95 mediated apoptosis either via increase of intracellular ... PI3K-independent anti tumor activity implied that there were potential side effects associated with the use of LY29 It also further corroborated the role of H2O2 as an apoptotic effector, whereby ... downregulate activity of the complex (Jimenez et al., 1998), were the first to describe the cloning and characterization of p65-PI3K, a mutant of the regulatory subunit of PI3K, which includes the initial...
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Báo cáo y học: "Methotrexate therapy associates with reduced prevalence of the metabolic syndrome in rheumatoid arthritis patients over the age of 60- more than just an anti-inflammatory effect? A cross sectional study" pptx
... of the MetS had a non-significant association (data not shown) In addition to the originality of most of the findings, this study has several other strengths These include the use of all of the ... higher rates of the MetS [40] This discrepancy may be a consequence of the ongoing inflammatory burden in the RA population, altering some of the components of the metabolic syndrome The factors ... leflunomide, anti- tumour necrosis factor therapy, glucocorticoid use and NSAID use the odds of having the MetS, independently of any of these factors, suggesting the possibility of a drug-specific...
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A study into the different mechanisms of anti cancer effect of docosahexanoic acid in colon cancer cells
... nomenclature of fatty acid molecules, PUFAs are classified into different groups on the basis of the position of the first double bond from the methyl terminus of the hydrocarbon chain of the molecule ... accumulation of ROS prolonged the activation of JNK when NF-κB is inhibited This may be due to either the decreased expression of the antioxidant enzymes or the increased expression of the p450 genes ... proliferation and viability of colon cancer cell lines (2) To study the apoptotic effects of the n-3 PUFA, DHA in the colon cancer cell line, HT-29 (3) To elucidate the effect of the MAPK signaling pathways...
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REINCARNATION AND THE LAW OF KARMA A STUDY OF THE OLD-NEW WORLD-DOCTRINE OF REBIRTH, AND SPIRITUAL CAUSE AND EFFECT potx
... the builders of the Pyramids the people of the Sphinx Whether these people were the direct descendants of the people of destroyed Atlantis, the home of the Ancient Wisdom—or whether they were a ... Reincarnation, and to the ideas of the complex soul As the survivors of Atlantis are believed to have been the ancestors of the Egyptians on the one hand, and of the Ancient Peruvians on the other the two ... among the vanished peoples of the past, we find ourselves irresistibly borne toward that ancient land of mystery the home of the mystics and occultists of the past the land of Isis the home of the...
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the effect of monetary incentive on effort and task performance a study of vietnamese company
... duties in the company All of them are utility maximizes; therefore, there is no ground to believe that they will act on the interest of the company On the other hand, it is not easy to mediate these ... the importance of influencing workers to accomplish task performances Many years later, this was the premise of the appearance of the term “motivation” and then it has rapidly become one of the ... For owners, they should be especially aware of the importance of motivation because only if they understand the importance of it, then can they implement incentive policy to motivate their employees...
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báo cáo hóa học:" Protective versus pathogenic anti-CD4 immunity: insights from the study of natural resistance to HIV infection" potx
... diseases The depletion of the CD4 T lymphocytes is the hallmark of the progression of HIV infection and, in the absence of antiviral treatment, the main contributor to the development of opportunistic ... distinct monoclonals, two of them preventing, the third one accelerating the development of the disease [40] The effect of each reagent on the signaling activated by CD4 via the p56lck interacting ... revitalization of the anti- CD4 treatment notion with new, humanized anti- CD4 mAbs [33] Indeed, the usage of this approach has been hampered by the complexity of its effects on the immune system...
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Báo cáo hóa học: " Transcriptional responses in the adaptation to ischaemia-reperfusion injury: a study of the effect of ischaemic preconditioning in total knee arthroplasty patients" docx
... patients A comparison of the gene expression profiles of the control and IPC groups indicated that the effect of ischaemic preconditioning was correlated with increased expression of genes involved ... carried out the experimental work including the extraction of RNA, validation of microarray data by real-time PCR and the analysis of serum samples The microarray experiment and the analysis of array ... therefore, was excluded from the study Preconditioning protocol All patients had a tourniquet placed on the upper thigh of the operative limb after the administration of spinal anaesthesia as per normal...
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báo cáo hóa học:" Multi-modal-analgesia for pain management after Hallux Valgus surgery: a prospective randomised study on the effect of ankle block" doc
... partial meniscectomy [11] The power of the study was based on the assumption that 70 % of the control group of patients would experience pain to that extent that intake of further analgesic after ... 15 cc of saline The performance of the ankle block was; "the posterior tibial nerve" by cc posterior to the medial malleoli, "the peroneal nerve, superficial and deep" by cc on dorsum of the foot ... of Anesthesiology functional classes 1–2 patients undergoing elective Hallux Valgus surgery ad modum Turan were studied [4] The study protocol, a prospective randomised study of the effects of...
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Báo cáo hóa học: " A study on the effect of different chemical routes on functionalization of MWCNTs by various groups (-COOH, -SO3H, -PO3H2)" potx
... on the outer walls of MWCNTs The presence of the different chemical groups (-COOH, -SO H, and -PO3H2) on the walls of the MWCNTs and their quantitative amounts have also been studied by EDX The ... upon the chemical route followed In the present study, different chemical routes have been used for the functionalization of CNTs with the -COOH, -SO3H, and -PO3H2 groups, and their effects on the ... band) in the graphene sheet The ratio of the intensities of the D and G bands (ID/IG) is generally taken as a measure of the defect concentration This ratio has been calculated for the different...
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Báo cáo khoa học: " The Antinociceptive and Anti-inflammatory Effect of Ethylacetate Extracts from Bang-Poong (Radix ledebouriellae) on the Freund’s Adjuvant-Induced Arthritis in Rats" pot
... this study Although the significant suppressive effect of BPE on arthritis in rats was demonstrated in this study, the most effective component of whole BP is still unknown To find the most effective ... (3) These results indicate that the Fos protein can be used as a neuronal marker of nociception Therefore reduced spinal Fos expression by the treatment of BP in this study suggested that the antinociceptive ... inflamed soft tissue] － [area of normal soft tissue] (3) Area of bone proliferation = [area of proliferated bone] － [area of normal bone] S erum concentration of interleukin-6 At the end of whole...
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Báo cáo lâm nghiệp: "Effect of contrasting water supply on the diameter growth of Norway spruce and aspen in mixed stands: a case study from the southern Russian taiga" pot
... different proportions and with admixture of some other deciduous species are typical in the region of the southern European taiga The area of the southern European taiga is characterised by moderate ... forest (at the same elevation as previous and at place which was 0.4 m higher), and the last hole was bored at the highest point of the plot 0.9 m above the well level The depth of the last hole ... half of summer and reached maximum in middle of July The stem growth of the spruce had maximum in early July and was significant since early May to the late August The mean growth rate of the...
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Báo cáo toán học: "Iodine Alters Gene Expression in the MCF7 Breast Cancer Cell Line: Evidence for an Anti-Estrogen Effect of Iodine" doc
... changes in the estrogen receptor have been found in the breasts of iodine deficient rats compared to normal euthyroid animals suggesting that the iodine pathway may augment the synthesis of the estrogen ... As the body of evidence builds, the importance of iodine on the maintenance of healthy breast tissue and its role in carcinogenesis becomes clearer Unveiling iodine’s mechanism of action is of ... or enhancements of current therapies In this study we provide the first gene array profiling of an estrogen responsive breast cancer cell line demonstrating that the combination of iodine and iodide...
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Báo cáo y học: "The anti-inflammatory effects of levocetirizine - are they clinically relevant or just an interesting additional effect" pptx
... considerable interest in the effect of anti- inflammatory drugs on the pro-inflammatory processes responsible for the manifestations of allergic disease Antiinflammatory effects independent of H1-receptor ... parameters Furthermore, use of rescue therapy (cromolyn and salbutamol) was significantly lower in the levocetirizine group The authors concluded that their findings further support the theory of "united ... investigating the mechanisms underlying the effects of H1-antihistamines have indicated that, in addition to their being a potent antihistamine, levocetirizine exhibits anti- allergic/antiinflammatory effects,...
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Báo cáo khoa học: "The in vivo study on the radiobiologic effect of prolonged delivery time to tumor control in C57BL mice implanted with Lewis lung cancer" pdf
... Page of Figure The effects of different interfraction interval time on the TGDT The mean ± SE of tumor growth time in the group of the control is 8.09 ± 0.61 days P < 0.05 as compared with the ... means ± SEM The level of significance used for all comparisons was P < 0.05 Results The effect of the total interfraction interval time on the growth of tumor tissues Figure shows the tumor growth ... elongation of the intervals, but not significantly [16,17] They contributed the confiliction of the results in vitro and in vivo to reoxygenation In this study, we attempt to evaluate the impact of prolonged...
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Báo cáo khoa học: "Delineation in thoracic oncology: a prospective study of the effect of training on contour variability and dosimetric consequences" potx
... adapt the CTV to the natural anatomical borders of tissue, The first family of indices is based on volume ratios: the volume ratio (VR) between the volume of the student and the volume of the expert, ... by the expert was mm.13 The volume of the CTV obtained by the expert was 214.3 cm3 The average volume of the CTV for the residents was 242.3 cm3 (162.9 to 495.7 cm3) before the course After the ... OV and KI indices was applied on the contours of the expert Then, the different indices for the tumor became: 1.04, 1.04, and 53% The study of the dosimetric effect on organs at risk was also...
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Báo cáo y học: "Persistence with anti-tumour necrosis factor therapies in patients with psoriatic arthritis: observational study from the British Society of Rheumatology Biologics Register" pps
... 'the length of time from initiation to discontinuation of therapy' [18] Patients were censored at the date therapy was stopped, the date the patient was switched to another anti- TNF therapy, the ... rates There were no significant associations between any of the other potential predictors Persistence with the second anti- TNF therapy A total of 178 patients received a second course of therapy ... date at the end of follow-up or the date the patient died, whichever came first As patients may often stop treatment during an infection or elective surgery, any gaps in the use of the same anti- TNF...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25